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TECHNION - RAPPAPORT FACULTY OF MEDICINE

Curriculum Vitae

January 2017

1. PERSONAL DETAILS

Full Name Mogher Khamaisi

Date and place of birth: 08/15/1971, Nazareth, Israel

2. ACADEMIC DEGREES

1990-1993 B.Sc. in Biology, Faculty of Life Science, Ben-Gurion

University of the Negev, Beer-Sheva, Israel.

Graduated with honors.

1994-1995 M.Sc. in Clinical Biochemistry, Faculty of Health Sciences,

Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Supervisor: Prof. Nava Bashan.

Graduated with honors.

1996-2001 Ph.D. in Clinical Biochemistry, Faculty of Health Sciences,

Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Supervisor: Prof. Nava Bashan.

Thesis title: "The effect of the antioxidant lipoic acid on

glucose homeostasis in muscle and liver in diabetic animals".

1995- 2002 M.D. Medical School, the Faculty of Health Sciences, Ben-

Gurion University of the Negev, Beer-Sheva, Israel.

2002- 2004 Post Doctoratal fellowship. in Endocrinology, Diabetes

Center, Hebrew University-Hadassah Hospital, Jerusalem,

Israel.

Mentor: Prof. Itamar Raz.

Thesis title: "The role of Endothelin Converting Enzyme in

the development of diabetic kidney disease: in vitro and in

vivo study".

2003-2004 Internship. Medical internship, Bikur Cholim Hospital,

Jerusalem, Israel.

2004-2008 Residency in Internal Medicine. Specialty in Internal

Medicine, Internal Medicine B, Hadassah University Hospital,

Jerusalem, Israel.

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2009-3/2012 Senior in Internal Medicine. Internal Medicine C, Rambam

Medical Center, Haifa, Israel.

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2009-2011 Sub specialty in Adult Endocrinology. Institute of

Endocrinology, Diabetes & Metabolism, Rambam Medical

Center, Haifa, Israel.

04/20012

8/2015

Research Fellowship (Post. Doctorate) in Endocrinology.

Section of Vascular Cell Biology, Joslin Diabetes Center,

Harvard Medical School, Boston, MA.

Mentor: Dr. George King.

02/2017–to

date

Director of Internal Medicine D. Rambam Medical Center,

Haifa, Israel

3. ACADEMIC APPOINTMENTS

2010-4/2012 Assistant Professor, Rappaport Faculty of Medicine,

(January 2016) Technion-Institute of Technology, Haifa, Israel.

2007

Instructor of Medicine, Hebrew University Hadassah Medical

School, Jerusalem, Israel.

4. PROFESSIONAL EXPERIENCE

1999 Summer research program with Prof. M. J. Charron in Albert Einstein

College of Medicine, NY.

2002 Summer research program with Prof. Allan Flyvbjerg in Aarhus

University Hospital, Denmark.

2003 Summer course, the 3rd

Oscar Minkowski Advanced Postgraduate

Course in Clinical Diabetes and its Complications, Kaunas, Lithuania.

2008

Chief Resident in Internal Medicine, Hadassah Medical Center,

Jerusalem, Israel.

5. RESEARCH INTERESTS

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1. Inducible Pluripotent stem cells (iPSC). Programming methods, culturing,

proliferation and differentiation to endothelial cells.

2. Mechanisms involved in wound healing in diabetes.

3. Molecular basis of diabetes complications (oxygen species, hypoxia inducible

factor's, protein kinase C pathway, p53, STAT-3, the mitogen-activated protein

kinase family, and the phosphatidylinositol 3-kinase).

4. Regulation of intra-renal hemodynamic in diabetes: role of endothelin,

endothelin converting enzyme and nitric oxide systems in the diabetes-associated

vascular dysfunction.

5. Pathophysiology and prevention of radio-contrast nephropathy.

6. TEACHING EXPERIENCE

Courses:

2009- 2012 Coordinator and lecturer for third year students in Medical School, in the

course "Endocrinology". Rappaport Faculty of Medicine, Technion,

Haifa, Israel.

2003-2007 Lecturer for second year students in Pharmacy, in the course "Human

Nutrition in Health and Disease". Faculty of Medicine, Hebrew

University, Jerusalem, Israel.

2003-2007 Lecturer for second year students in Nurse Schools, in the course

"Nutrition". Faculty of Medicine, Hebrew University, Jerusalem, Israel.

1995-1999 Teaching assistant and laboratory instructor for the course "Clinical

Biochemistry" for medical students and students at the school for Medical

Laboratory. Faculty of Health Sciences, Ben-Gurion University, Beer-

Sheva, Israel.

1995-1996 Teaching assistant for the course "Chemistry for medical students",

Faculty of Health Sciences, Ben-Gurion University, Beer-Sheva, Israel.

1996-2000 Coordinator and lecturer of a basic course "Diabetes: classification,

complications and therapy " for Ashel Hanasi high school.

Clerkships:

2015-to date Lecturer for the American students in the third year of medical school

during the Internal Medicine round (Internal Medicine D). Rappaport

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Faculty of Medicine, Technion, Haifa, Israel.

2009-2012 Lecturer for students in the sixth year of medical school during the

endocrinology rounds. Rappaport Faculty of Medicine, Technion,

Haifa, Israel.

2009-2012 Lecturer for students in the fourth year of medical school during the

internal medicine departmental rounds. Rappaport Faculty of

Medicine, Technion, Haifa, Israel.

2004-2008 Lecturer for students in the fourth and sixth year of medical school

during the internal medicine departmental rounds. The Faculty of

Medicine, Hebrew University, Jerusalem, Israel.

7. PUBLIC PROFESSIONAL ACTIVITIES

2016- to date

20015-to date

Reviewers for Diabetes/Metabolism and Reasearch Reviews

Reviewers for the Israeli Science Foundation (ISF).

20015-to date Ad-hoc reviewers in Journal of Dental Research.

20014-to date Ad-hoc reviewers in Journal of Clinical Endocrinology and

Metabolism (JCEM).

20014-to date Ad-hoc reviewers in Endocrinology.

2006-to date Ad-hoc reviewers in Kidney International.

2005-to date Ad-hoc reviewers in Nephrol Dial & Transpl.

2006-to date Ad-hoc reviewers in Vascular Disease Prevention.

8. MEMBERSHIP IN PROFESSIONAL SOCIETIES

- NATIONAL

2002-current Israeli Medical Association

2004-current

2011-current

Israeli Society of Internal Medicine

Israeli Endocrinology Society

2016-current Clinical Research Institute at Rambam (CRIR)

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- INTERNATIONAL

1997-1998 European Association for the Study of Diabetes (EASD)

2004-2011 American Physiology Society

2012-current American Diabetes Association (ADA)

9. HONORS

1991 Ben-Gurion University dean’s award for an excellent Arab student.

1999-2001 Ministry of Sciences award for an excellent young scientist.

2001-2002 The Israel Diabetes Association, small research grant for young

scientist.

2002-2003 The Golda Meir Fellowship for postdoctoral studies, Hebrew

University of Jerusalem.

2005 Hebrew University, Faculty of Medicine, Excellent Lecturer in Internal

Medicine.

2006-2007 The Israeli Society of Internal Medicine- a fellowship for young

internist.

2006-2009 Ma'of Fellowships established by the Kahanoff Foundation, planning

and grants committee of the Council of Higher Education.

2008 Hebrew University, Faculty of Medicine, Excellent Lecturer in Internal

Medicine

2010 Israel Endocrine Society Chowers Award.

2011 Technion, Faculty of Medicine, Excellent Lecturer in Endocrinology.

2012 Rambam Medical Center Fellowship Award.

2013 The American Physicians and Friends (APF) for Medicine in Israel

fellowship grant.

2014 Rappaport Faculty of Medicine, Technion-Israeli Institute of Technology

for supervising the best research project (Dr. Shira Molcho).

2014 The William Randolph Hearst Fellowship. Harvard Medical School,

Boston, MA

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10. PATENT

2015 Wound healing in diabetes (co-inventor with Dr. George King): US Patent

Pending 62/133,222.

11. STUDENTS AND INSTRUCTION

POST.DOC

2017- to date Hiba Yaseen. Title: " Role of stem cells in wound healing"

PH.D.

2017-to date Atili Mosseri. Title: " Role of insulin and insulin signaling in wound

healing in diabetes".

2010-2014 Nairuz Abu-Saleh. Title: "Effect of Increased Intra-Abdominal Pressure on

Kidney Function in Health and Disease".

(Co-supervisor with Prof. Zaid Abassi).

M.Sc.

2011- 2014 Hala Toukan, M.Sc. student. Title: Detection and localization of endothelin

converting enzyme (ECE)-1 in the human diabetic kidney.

(Co-supervisor with Prof. Zaher Azzam).

2005-2007 Vitali Shiloh, M.Sc. student. Title: Diabetes, ECE and predisposition to ATN

(Co-supervisor with Prof. Samuel Heyman).

2005-2007 Hatem Swaed, M.Sc. student. Title: The metabolic syndrome in the Arab

community.

2003-2005 Rachel Dahan, M.Sc. student. Title: The role of endothelin converting

enzyme in the development of vascular dysfunction in diabetes.

(Co- supervisor with Dr. Rafel Nesher and Prof. Itamar Raz).

Basic Science

2003 Jack Mesholam, Title: The relation between abdominal to peripheral fat

tissues and the development of diabetes: surgery as strategy for diabetes

treatment (Co-supervisor with Prof. Itamar Raz).

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2004 Vladimir Michalivsky, Title: The relation between abdominal to

peripheral fat tissues and the development of diabetes: surgery as

strategy for diabetes treatment (Co-supervisor with Prof. Itamar Raz).

MD Thesis 2014 Lourdes Ramirez, Title: Characterization of iPS cells for Wound Healing in

Diabetic Patients. Joslin Diabetes Center, Harvard Medical School,

Boston, MA, USA.

2013 Maher S. Budron, Title: Characterization of Human iPS Cells to

Endothelial cells. Joslin Summer Research Internship, Mitchem

Fellows Program, CIRRUS; Joslin Diabetes Center, Harvard Medical

School, Boston, MA, USA.

2009-2012 Shira Molcho, Title: Role of vascular dysfunction in the pathogenesis of

jaw osteonecrosis. Technion, Haifa, Israel.

12. RESEARCH GRANTS

2004-2007 The Russell Berrie Foundation and D-Cure, Diabetes Care in Israel. "The

role of endothelin converting enzyme in vascular dysfunction in diabetes".

(PI) (140,000$).

2008-2009 The Cabakoff Research Endowment Fund Grant. "Development of an

animal model for bisphosphonate-related osteonecrosis of the jaws". (PI,

together with Dr. Sharon Elad, Department of Oral Medicine, Hadassah

Hospital, Ein-Kerem) (16,000 $).

2008-2012 The Israel Science Foundation (ISF). "Regional renal hypoxia and altered

hypoxia adaptation in diabetes: risk factors for development of chronic

and acute renal failure". (PI, together with Prof. Samuel N Heyman,

Hadassah Hospital, Mt. Scopus) (NIS 628,000).

2015-to date

2016-to date

Ruth and Bruce Rappaport Faculty of Medicine grant "The potential effect

of smoking on renal hypoxia and Endothelin Converting Enzyme in

diabetic and non –diabetic rats: in vivo and in vitro study".

Clinical Research Institute at Rambam (CRIR)" Using human inducible

stem cells for wound healing in patients with diabetes".

13. PUBLICATIONS

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Theses

1. Ph.D. thesis: Effect of the antioxidant Lipoic acid on glucose homeostasis in

muscle and liver of diabetic animals. Faculty of Health Sciences, Department of

Clinical Biochemistry, Ben-Gurion University of the Negev, Beer - Sheva, Israel,

2001.

Refereed papers in professional journals

1. Basic research

1. Khamaisi M, Potashnik R, Tritschler H, Wessel K, and Bashan N: Effect of Lipoic acid

on glucose homeostasis and muscle glucose transporters in diabetic rats. Diabetes and

Metabolism-Journal for Applied Diabetology 5:50-54, 1996.

2. Khamaisi M, Potashnik R, Tirosh A, Demshchak E, Rudich A, Tritschler H, Wessel K,

and Bashan N: Lipoic acid reduces glycemia and increases muscle GLUT 4 content in

streptozotocin-diabetic rats. Metabolism, Clinical and Experimental 46: 763-768, 1997.

3. Wiznitzer A, Ayalon N, Hershkovitz R, Khamaisi M, Trischler H, and Bashan N:

Lipoic acid reduces occurrence of neural tube defects in offspring of streptozotocin-

induced diabetic rats. American Journal of Obstetrics and Gynecology 180:188-193, 1999.

4. Khamaisi M, Rudich A, Potashnik R, Tritschler H, Gutman A, and Bashan N: Lipoic

acid acutely induces hypoglycemia in fasting non diabetic and diabetic rats. Metabolism,

Clinical and Experimental 46:763-768, 1999.

5. Rudich A, Tirosh A, Potashnik R, Khamaisi M, and Bashan N: Lipoic acid protects

against oxidative stress induced impairment in insulin stimulation of protein kinase B and

glucose transport in 3T3-L1 adipocytes. Diabetologia 42:949-957, 1999.

6. Khamaisi M, Rudich A, Beeri I, Pessler D, Friger M, Gavrilov V, Trishler H, and

Bashan N: Metabolic effects of linilenic acid- a lipoic acid conjugate in streptozotocin

diabetic rats. Antioxidants and Redox Signaling 4: 523-535, 1999.

7. Khamaisi M, Kavel O, Rosenstock M, Porat M, Yuli M, Kaiser N, and Rudich A:

Effect of inhibition of glutathione synthesis on insulin action: in vivo and in vitro studies

using buthionine sulfoximine. Biochemical J 349:579-586, 2000.

8. Shafrir E, Spielman S, Nachliel I, Khamaisi M, Bar-On H, and Ziv E: Treatment of

diabetes with vanadium salts-general overview and amelioration of nutritionally diabetes

in the Psammomys obesus gerbil. Diabetes Metab Res Rev 17:55-66, 2001.

9. Khamaisi M, Flyvbjerg A, Haramati Z, Raz G, Wexler I, and Raz I: Effect of mild

hypoinsulinemia on the growth hormones/insulin like factor I system in experimental

diabetes. International Journal Experimental Diabetes Research 3:257-264, 2002.

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10. Raz I, Wexler I, Weiss O, Flyvbjerg A, Segev Y, Rauchwerger A, Raz D, and

Khamaisi M: The role of insulin in inducing diabetes nephropathy: Renal hypertrophy and

the IGF system in the diabetic sand rat. Nephrology Dialysis Transplantation 18:1-6, 2003.

11. Keynan S, Khamaisi M, Dahan R, Barnes K, Jackson CD, Turner AJ, and Raz I:

Increased expression of endothelin converting enzyme -1c isoform in response to high

glucose in endothelial cell line. Journal of Vascular Research 41:131-40, 2003.

12. Khamaisi M, Keynan S, Dahan R, Burstyn M, Reinhartz E, Raz I: Nitric oxide

production in the chronic phase of STZ diabetic rats. Nephron Physiology 102:72-80,

2005.

13. Khamaisi M, Søndergaard M, Dagnaes-Hansen F, Jensen TG, Segev Y, Landaw D,

and Flyvbjerg A: Normalization of kidney and liver growth by non-viral hGH producing

vector in hypophysectomized mice. Growth Hormone & IGF Research 17(4): 279-287,

2007.

14. Khamaisi M, Regev E, Yarom N, Avni B, Leitersdorf E, Raz I, and Elad S: Diabetes

as a Risk Factor for Bisphosphonate-Induced Jaw Osteonecrosis. The Journal of Clinical

Endocrinology & Metabolism 92(3):1172-5, 2007.

15. Rosenberger C, Khamaisi M, Abassi Z, Shilo V, Weksler-Zangen S, Goldfarb M,

Shina A, Zilberstat F, Eckardt KU, Rosen S, and Heyman SN: Adaptation to hypoxia in the

diabetic rat kidney. Kidney Int. 73(1):34-42, 2008.

16. Khamaisi M, Raz I, Shilo V, Shina A, Rosenberger C, Dahan R, Meidan R, Abassi Z,

and Samuel N Heyman: The effect of diabetes and radiocontrast media on renal

expression of endothelin converting enzyme-1. Kidney Int. 74(1):91-100, 2008.

17. Rosenberger C, Khamaisi M, Goldfarb M, Shina A, Shilo V, Rosen S, and Heyman SN:

Acute Tubular Injury in the Diabetic Rat: Studies in the Isolated Perfused and Intact kidney.

American Journal of Nephrology 28(5):831-839, 2008.

18. Khamaisi M, Dahan R, Hamed S, Abassi Z, Heyman S, and Raz I: Role of Protein

Kinase C in the Expression of Endothelin Converting Enzyme-1 in Endothelial Cell.

Endocrinology 150 (3):1440-1449, 2009.

19. Skarzinski G*, Khamaisi M*, Bursztyn M, Mekler J, Evdokimov P, Lan D, Ariel I:

Intrauterine growth restriction and shallower implantation site in rats with maternal

hyperinsulinemia are associated with altered NOS expression. Placenta 30(10):898-906,

2009. * These authors contributed equally to this work.

20. Karram T*, Khamaisi M*, Heyman S, Abassi Z: Urinary excretion of endothelin

receptors ETA and ETB in hypertensive patients and normotensive subjects. Kidney &

Blood Pressure Research 32(4):293-303, 2009. * These authors contributed equally to this work.

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21. Khamaisi M, Skarzinski G, Mekler J, Farid A, Shay S, Damouni R, Ariel I, Bursztyn

M: Hyperinsulinemia increased placenta Endothelin Converting Enzyme-1 expression in

trophoblasts. Am J Hypertens 25(1):109-14, 2012.

22. Yarnitsky D, Granot M, Nahman-Averbuch H, Khamaisi M, Granovsky Y:

Conditioned pain modulation (CPM) predicts duloxetine efficacy in painful diabetic

neuropathy. Pain 153(6):1193-8, 2012.

23. Abu-Saleh N, Ovcharenko E, Awad H, Goltsman I, Khamaisi M, Hoffman A,

Heyman SN, Winaver J, Abassi Z: Involvement of the endothelin and nitric oxide systems

in the pathogenesis of renal ischemic damage in an experimental diabetic model. Life Sci

91(13-14):669-75, 2012.

24. Nechemia-Arbely Y*, Khamaisi M*, Rosenberger C*, Koesters R, Shina A, Shriki A,

Klaus S, Rosen S, Rose-John S, Galun E, Axelrod J, Heyman SN: In Vivo Evidence of

HIF and STAT3 Cross-Talk in the Kidney in Response to Hypoxic and Non-Hypoxic

Stimuli. Clin Exp Pharmacol Physiol 40(4):262-72, 2013.

* These authors contributed equally to this work.

25. Molcho S, Peer A, Berg T, Futerman B, Khamaisi M: Diabetes Microvascular

Disease and the Risk for bisphosphonate-related Osteonecrosis of the Jaw: A Single Center

Study. J Clin Endocrinol Metab 98(11):E1807-12, 2013.

26. Abu Saleh N, Awad H, Khamaisi M, Armaly Z, Karram T, Heyman SN, Kaballa

A,Ichimura T, Holman J, Abassi ZA: Nephroprotective Effects of TVP1022, a non-MAO

inhibitor S-Isomer of Rasagiline, in Experimental Model of Diabetic Renal Ischemic

Injury. Am J Physiol Renal Physiol. 306(1):F24-33, 2014.

27. Ariel I, Skarzinski G, Kossovsky T, Belzer V, Knigin D, Khamaisi M, Abassi Z,

Bursztyn M. Ex vivo endothelin dependent contraction of the remodeled rat spiral artery.

Placenta. 35(9):702-8, 2014.

28. Lahoud Y, Hussein O, Shalabi A, Nativ O, Awad H, Khamaisi M, Matar I, Nativ O,

Abassi Z: Effects of Phosphodiesterase-5 Inhibitor on Ischemic Kidney Injury During

Nephron Sparing Surgery: Quantitative Assessment by NGAL and KIM-1. World J Urol.

2015 May 16. [Epub ahead of print]

29. Khamaisi M, Toukan H, Axelrod JH, Rosenberger C, Skarzinski G, Shina A, Meidan

R, Koesters R, Rosen S, Walkinshaw G, Mimura I, Nangaku M, Heyman SN: Endothelin-

converting enzyme is a plausible target gene for hypoxia-inducible factor. Kidney Int.

87(4):761-70, 2015.

30.He ZH, D’Eon SA, Tinsley LJ, Fitzgerald S, Hastings SM, Khamaisi M, Sun JK,

Turek

SJ, Schaefer EJ, King GL, Keenan HA: Cardiovascular Disease Protection in Long

Duration Type 1 Diabetes and Gender Differences. Diabetes Care. 38(5):e73-4, 2015.

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31. Bhatt S, Gupta MK, Khamaisi M, Martinez R, Gritsenko MA, Wagner BK, Guy Pe,

Busskamp V, Takatani T, Wu G, El Ouaamari A, Dirice E, Liew CW, Keenan HA, Smith

RD, Church G, Wagers AJ, Weiss R, Qian WJ, King GL, Kulkarni RN: Preserved DNA

Repair Pathway Protects From Complications in Long-standing Type 1 Diabetes. Cell

Metabolism 4;22(2):239-52, 2015.

32. Heyman SN, Leibowitz D, Mor-Yosef Levi I, Liberman A, Eisenkraft A, Elcalai R,

Khamaisi M, Rosenberger C: Adaptive Response to Hypoxia and Remote Ischemia

Preconditioning: A New HIF Era in Clinical Medicine. Acta Physiol (Oxf) 216(4):395-

406, 2016.

33. Khamaisi M, Keenan H, Katagiri S, Park K, Li Q, Yasutaka M, Qi W, Rask- Madsen

C, Orgill DP, Huang C, King GL: Persistent activation of PKC and inhibition of insulin

actions in fibroblasts from type 1 diabetes with CVD impaired wound healing. J Clin

Invest 126(3):837-53, 2016.

34. Kridin K, Bergman R, Khamaisi M, Weltfriend S: Tendencies in the prevalence of

chromate allergy in northern Israel and exposure to cement and detergents. Dermatitis

27(3):131-6, 2016.

35. Park K, Mima A, Li Q, Rask-Madsen C, He P, Mizutani K, Katagiri S, Maeda Y, Wu

IH, Khamaisi M, Preil SR, Maddaloni E, Sørensen D, Rasmussen LM, Huang PL, King

GL: Identification of Insulin’s Novel Pathway to Activate eNOS via Endothelin Receptor

B Expression and Ameliorate Atherosclerosis. JCI Insight. 2016 ;1(6). pii: e86574.

36. Katagiri S, Park K, Maeda Y, Rao TN, Khamaisi M, Li Q, Mima A, Lancerotto L,

Orgill DP, King GL: Augmenting Insulin Signaling in Endothelial Cells via IRS1

Overexpression Improves Angioblast Differentiation and Wound Healing in Diabetes and

Insulin Resistance. Diabetes 65(9):2760-71, 2016.

37. Kridin K, Khamaisi M, Weltfriend S: Cement-induced chromate occupational allergic

contact dermatitis: epidemiology, clinical characteristics and prognosis. Dermatitis

27(4):208-14, 2016.

38. Kridin K, Zelber-Sagi S, Khamaisi M, Cohen AD, Bergman R: Remarkable

differences in the epidemiology of pemphigus among two ethnic populations in the same

geographic region. J Am Acad Dermatol 75(5):925-930, 2016.

39. Qi W, Li Q, Liew CW, Rask-Madsen C, Lockhart SM, Rasmussen LM, Xia Y, Wang

X, Khamaisi M, Croce K, King GL. SHP-1 activation inhibits vascular smooth muscle

cell proliferation and intimal hyperplasia in a rodent model of insulin resistance and

diabetes. Diabetologia. 2016 Dec 9. [Epub ahead of print]

40. Kridin K, Khamaisi M, Grifat R. Is there an ethnic variation in the epidemiology of

Gonorrhea? A retrospective cross-sectional population-based study from northern Israel

over 15 years. Accepted in British Medical Journal, December 2016.

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41. Heyman SN, Khamasi M, Rosen S, Rosenberger C, Abassi Z. Potential Hypoxic

Renal Injury in Diabetics on SGLT-2 Inhibitors: Caution Regarding Concomitant Use of

NSAIDs and Iodinated Contrast Media. Diabetes Care. 2017 Jan 27. pii: dc162200. doi:

10.2337/dc16-2200. [Epub ahead of print]

2. Review papers

42. Khamaisi M, Wexler I, Skrha J, Strojek K, Raz I and Milicevic Z: Cardiovascular

disease in Type 2 diabetics. The Israel Medical Association Journal 5: 801-6, 2003.

43. Khamaisi M, Weinshtein C, Hancu N, Milicevic Z, and Raz I: Role of hyperglycemia

and insulin in the pathogenesis of diabetic cardiovascular complications. The Israel

Medical Association Journal 5:116-119, 2003.

44. Khamaisi M, Schrijvers BF, De Vriese AS, Raz I, and Flyvbjerg A: The emerging

role of VEGF in diabetic kidney disease. Nephrology Dialysis Transplantation 18:1427-30,

2003.

45. Khamaisi M, and Itamar Raz I: Mechanisms of endothelial dysfunction in diabetes-

The role of protein kinase C. Vascular Disease Prevention 4:305-312, 2006.

46. Heyman SN, Khamaisi M, Rosen S, and Rosenberger C: Renal parenchymal hypoxia:

a key role in the progression of chronic kidney disease. American Journal of Nephrology

18:998-1006, 2008.

47. Khamaisi M, Heyman SN: The role of hypoxia and HIF-mediated hypoxia adaptation

response in the progression of chronic kidney disease. Harefuah 148: 721-726, 2009.

48. Heyman SN, Rosen S, Khamaisi M, Idée JM, Rosenberger C: Reactive Oxygen

Species and the Pathogenesis of Radiocontrast-Induced Nephropathy. Investigative

Radiology 45: 188–195, 2010.

49. Heyman SN, Khamaisi M, Rosen S, Rosenberger C. In vivo models of acute kidney

injury. Drug Discovery Today: Disease Models 6: 51-56, 2010.

50. Heyman SN, Rosenberger C, Rosen S, Khamaisi M: Why is diabetes mellitus a risk

factor for contrast nephropathy. Biomed Res Int 1-8, 2013.

51. Peer A, Khamaisi M: Diabetes as a Risk Factor for Medication-Related

Osteonecrosis of the Jaw. Journal of Dental Research 94(2):252-260, 2015.

52. Khamaisi M, Balanson S. Stem cells for diabetes complications: a future potential

cure. Accepted in Rambam Maimonides Medical Journal, December 2016.

3. Books and book chapters

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53. Khamaisi M, Rudich A, and Bashan N: Effect of

transporters in streptozotocin-induced diabetic rat. In Jurgen Fuchs, Lester Packer, Guido

Zimmer. Lipoic Acid in Health and Disease. Marcel Dekker, New York, 269-278, 1996.

54. Khamaisi M, Wexler I, and Raz I: Cardiovascular disease in Type 2 diabetes. In:

Diabetes: From Research to Diagnosis and Treatment. Edited by Raz I, Shafrir E.

Publisher: M. Dunitz and Francis Associates U.K. 2002.

55. Khamaisi M, Symmer L, and Raz I: Thiazolidinediones in Cardiovascular Risk in

Type 2 Diabetes Mellitus, In: Cardiovascular risk in Type 2 diabetes mellitus: assessment

and control. Edited by Hancu N, Springer-Verlag, NY, 193-203, 2002.

56. Heyman SN, Rosen S, Khamaisi M, Rosenberger C: Hypoxia, Oxidative Stress and

the Pathophysiology of Contrast-Media-Induced Nephropathy. For: Oxidative Stress in

Basic Research and Clinical Practice: Studies on Renal Disorders. Miyata T, Eckardt KW,

Nangaku M (Eds), 2010.

57. Khamaisi M, Park K, Li Q, King GL. Pathophysiology of Microvascular

Complications, In: Diabetes Complications, Comorbidities and Related Disorders. Enzo

Bonora, Ralph A. DeFronzo, 2017.

Research reports

58. Khamaisi M, Regev E, Yarom N, Avni B, Leitersdorf E, Raz I, and Elad S: Diabetes

link to bisphosphonat related jaw osteonecrosis. Endocrine News, page 5, March 2007.

Other publications

Editorial

59. Khamaisi M, and Raz I: Diabetes epidemic and the thrifty gene. The Israel Medical

Association Journal 4:720-721, 2002.

Case Reports

60. Khamaisi M, Shoenfeld Y, and Orbach H: Guillain-Barre’ syndrome following

hepatitis B vaccination: a case report and summary of the literature. Clin Exp Rheumatol.

22: 767-70, 2004.

61. Abu Fanne R, Khamaisi M, Mevorach D, Leitersdorf E, Berkman N, Laxer U, and

Maly B: Spontaneous rupture of lung Echinococcal cyst causing an anaphylactic shock

and respiratory distress syndrome. Thorax 61(6):550, 2006.

62. Khamaisi M, Anner H, Marincheva G, Leitersdorf E, and Bogot N: Stent Graft in

Treatment of Penetrating Aortic Ulcer. Journal of the American Society of

Echocardiography 835:e4-e6, 2006.

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63. Fridlender ZG, Khamaisi M, and Leitersdorf E: Cytomegalovirus infection associated

with thromboembolic events - a new indication for anticoagulation? The American Journal

of the Medical Sciences 334(2):111-4, 2007.

64. Khamaisi M and Lietersdorf E: Severe hypoglycemia from clarithromycin-repaglinide

drug interaction. Pharmacotherapy 28 (5):682-4, 2008.

65. Khamaisi M: Severe Hypoglycemia from Repaglinide-Brotizolam Drug Interaction: a

case report and literature review. Diabet Med 29(9):1214-5, 2012.

66. Naccache DD, Nseir WB, Herskovitz MZ, Khamaisi M. Diabetic neuropathic

cachexia: a case report. J Med Case Rep. 8:20, 2014.

67. Abu Arisha M, Levy Y, and Khamaisi M. Thoracic aortic aneurysm in patient with

brucellosis. Accepted in The American Journal of the Medical Sciences. January 2017.

68. Shuker O, Khamaisi M. When patient/family expectations and hospital protocol

conflict. J Clin Med Res. 2017 Feb;9(2):176-177.

Images

69. Khamaisi M, Medina A, Mazouz B, and Boher M: Imaging coronary sinus infection

in pacemaker electrode with [18

F]-Fluorodeoxyglucose Positron Emission Tomography.

The Journal of Cardiovascular Electrophysiology 19(12):1327-8, 2008.

Commentaries

70. Khamaisi M, Elad S. Re: Intravenous Bisphosphonate Therapy and Inflammatory

Conditions or Surgery of the Jaw: A Population-Based Analysis. J Natl Cancer Inst. 16;

100(2):155, 2008.

71. Elad S, Yarom N, Khamaisi M. Re: Implant placement with or without simultaneous

tooth extraction in patients taking oral bisphosphonates: postoperative healing, early

follow-up, and the incidence of complications in two private practices. J Periodontol.

79(4):584-5, 2008.

72. Heyman SN, Khamasi M, Rosen S, Rosenberger C, Abassi Z. IncreasedHematocrit

During Sodium-Glucose Cotransporter 2 Inhibitor Therapy. Accepted in Journal of

Clinical Medicine Research, December 2016.

Publications in Hebrew

באלף השלישי'. חלום או מציאות. בספר 'סוכרת-, איתמר רז: השתלת תאי בטאמור'יר ח'מאיסי. 1

, 17-22עריכת טומי הירשקוביץ, איתמר רז, חוליו וינשטיין. פורסם ע"י האגודה הישראלית לסוכרת, 2002 .

בהופעת סיבוכי סוכרת Protein kinase Cאיתמר רז: תפקיד החלבון ,מור'יר ח'מאיסי .2

יו וינשטיין. פורסם מקרו וסקולרים. בספר 'סוכרת'. עריכת יאיר יודפת, איתמר רז, חול-מיקרו . 2007, 194-199ע"י האגודה הישראלית לסוכרת,

15

בספר המדריך : הטיפול בסיבוכי סוכרת: מכף רגל ועד הראש. מור'יר ח'מאיסיאביבית כהן, .3לטיפול בסוכרת. עריכת אביבית כהן, עופרי מוסנזון, איתמר רז. פורסם ע"י המועצה

2017הלאומית לסוכרת,

: תאי גזע הומניים לטיפול בסיבוכי סוכרת: מציאות או חלום ? עריכת סימור'יר ח'מאי .4 2017אביבית כהן, עופרי מוסנזון, איתמר רז. פורסם ע"י המועצה הלאומית לסוכרת,

Paper under considerations

1. Pober DM*, Khamaisi M*, Hastings S, D’Eon S, Tinsley L,. King GL, and

Keenan HA: Lower Mortality in Insulin Pump Users with Type 1 Diabetes of

Chronic Duration. Under review in Journal of Clinical Endocrinology and

Metabolism, November 2015.

2. Qi W, Li Q, Liew CW, Yu E, Rask-Madsen C, Park K, Khamaisi M, Maeda Y,

Croce K, King GL: Modulation of SHP-1 Expression to Inhibit Enhanced Vascular

Smooth Muscle Cell Mitogenesis and Restenosis in Insulin Resistance. Submitted

to Diabetes, January 2016.

3. Granovsky Y; Nahman-Averbuch H; Khamaisi M; Yarnitsky D; Granot M: Pro-

nociceptive pattern of pain modulation characterizes patients with painful diabetic

neuropathy. Submitted to Pain, December 2016.

4. Maddaloni M, D’Eon S, Hastings S, Tinsley L, Khamaisi M, Bouxsein ML,

Napoli N, Fouda SMR, KeenanHA: Protective frm low bone mineral density in

extreme duration type 1 diabetes. Submitted to Lancet, January 2016.

14. CONFERENCES

1. Bashan N, Khamaisi M, Vaknin U, and Potashnik R: Effect of lipoic acid on glucose-

Homeostasis and muscle glucose transporters in diabetic rats. The 30th

annual meeting of

the European Association for the Study of Diabetes, Düsseldorf, Germany, 1994.

(Diabetologia 37: A60-A60, 1994) (Talk).

16

2. Khamaisi M, Potashnik R, Peleg N, Barnea E, Tritschler H, Wessel K, and Bashan N:

Effects of lipoic acid on muscle GLUt-4 protein and messenger RNA in streptozotocin

diabetic rats. The 30th

annual meeting of the European Association for the Study of

Diabetes, Düsseldorf, Germany, 1994. (Diabetologia 38, A9-A9, 1995) (Poster).

3. Khamaisi M, Tirosh A, Demshchak E, Rudich A, Tritschler H, Potashnik R, and

Bashan N: Hypoglycemic effect of lipoic acid: mode of action in normal and

streptozotocin diabetic rats. The 32th

annual meeting of the European Association for the

Study of Diabetes, Vienna, Austria, 1996. (Diabetologia 39, A139, 1996) (Poster).

4. Potashnik R, Ayalon N, Khamaisi M, Wiznitzer A, and Bashan N: Lipoic acid

treatment decreases neural tube defects in fetuses of diabetic rats. The 33th

annual meeting

of the European Association for the Study of Diabetes, Helsinki, Finland, 1997.

(Diabetologia 40, 2301-2301, 1997) (Poster).

5. Rudich A, Tirosh A, Khamaisi M, Pessler D, Potashnik R, and Bashan N: Putative role

for oxidative stress in adipocyte and skeletal muscel insulin resistance. The 34th

annual

meeting of the European Association for the Study of Diabetes, Barcelona, Spain, 1998.

(Diabetologia 41 (Supp 1), A34, 1998) (Poster).

6. Khamaisi M, Gutman A, Rudich A, Potashnik R, Tritshler HJ, and Bashan N:

Inhibition of hepatic glucose production by lipoic acid is associated with increased acyl-

carnitine production. The 34th

annual meeting of the European Association for the Study of

Diabetes, Barcelona, Spain, 1998. (Diabetologia 41 (Supp 1), A203, 1998) (Poster).

7. Bashan N, Rudich A, Tirosh A, Potashnik R, and Khamaisi M: Lipoic acid protects

against oxidation-induced inuslin resistance in 3T3-L1 adipocytes. The 59th

annual

meeting of the America Diabetes Association, San Diego, CA, 1999. (Diabetes 48 (Supp

1), A261, 1999) (Poster).

8. Rudich R, Khamaisi M, Tirosh A, Kavel O, Potashnik R, and Bashan N: Lipoic acid

protects against oxidation -induced insulin resistance through a GSH independent

mechanism. FASEB Summer Course on Glucose Transporter Biology, Snowmass, CO,

1999.

9. Rudich A, Khamaisi M, Tirosh A, Kavel O, Potashnik R, and Bashan N: The

antioxidant lipoic acid protects against insulin resistance both in-vitro and in-vivo. The 3rd

congress of the European Association for Clinical Pharmacology and Therapeutics

(EACPT), Jerusalem, Israel, 1999. (Br. J. Clin. Pharmacol. p6, 1999) (Poster).

10. Khamaisi M, Kavel O, Rosenstock M, Porat M, Yuli M, Kaiser N, and Rudich A: The

effect of glutathione depletion on glucose homeostasis and insulin action. The 36 th

annual

symposium of the European Association for the Study of Diabetes, Jerusalem, Israel, 2000.

(Diabetologia Supp 1, A151:586, 2000) (Poster).

11. Khamaisi M, Keynan S, Dahan R, Turner A, and Raz I: Increased expression of

endothelin converting enzyme-1c isoform in response to high glucose in endothelial cell

17

line. The 63th

annual congress of the American Diabetes Association, New Orleans,

Louisiana, 2003. (Diabetes 52 (Supp 1): A176-A176, 2003) (Poster).

12. Khamaisi M, Keynan S, Bursztyn M, Dahan R, and Raz I: Nitric oxide production in

the subacute phase in diabetic rats. The 63th

annual congress of the American Diabetes

Association, New Orleans, Louisiana, 2003 (Diabetes 52(Supp 1); A187, 2003) (Poster).

13. Heyman S, Abassi Z, Khamaisi M, Shina A, Goldfarb M, and Rosen S: Diabetes

predisposes to Medullary Hypoxia with activation of hypoxia inducible factors (HIF) and

upregulation of endothelin B receptor (ETB). The 37 th

annual meeting of the American

Society of Nephrology, St. Louis, MO, USA, 2004. (J. Am. Soc. Nephrol. 15:468A, 2004)

(Poster).

14. Khamaisi M, Shilo V, Rosenberger C, Goldfarb M, Shina A, Meidan R, Raz I, and

Heyman SN: Diabetes and radiocontrast medium induce converting enzyme (ECE)-1 in

vitro and in the renal medulla: a plausible novel mechanism for elevated endothelin. The

40th

annual meeting of the American Society of Nephrology, San Francisco, California,

2007. (Poster).

15. Khamaisi M, Raz I, Rozenberger C, Meidan R, Abassi Z, Shilo V, and Heyman SN:

The effect of diabetes and radiocontrast media on renal expression of endothelin

converting enzyme-1. Tenth International Conference on Endothelin, Bergamo, Italy,

2007. (Poster).

16. Skarzinski G, Khamaisi M, Bursztyn M, and Ariel I: Could the placenta of the

maternal hyperinsulinemia intrauterine growth restriction (IUGR) rat be a model for

human growth restriction?. The 54th

Annual Meeting of the Paediatric Pathology Society,

Helsinki, Finland, 2008. (Poster).

17. Skarzinski G, Khamaisi M, Bursztyn M, Ariel I: IUGR and smaller

implantation site in the maternal hyperinsulinemia rat model are associated with

altered NOS expression. In the International Placenta Conference: Across the

Endometrium and into the Promised Land of the Placenta. Jerusalem, Israel, 2009.

(Talk).

18. Khamaisi M, Axelrod J, Karry R, Shina A, and Heyman SN: Endothelin converting

enzyme (ECE)-1: a plausible target gene for hypoxia inducible factor (HIF). Eleven

International Conferences on Endothelin, Montreal, Canada, 2009. (Poster).

19. Nechemia-Arbely Y, Rosenberger C, Khamaisi M, Koesters R, Shina A, Klaus S,

Shriki A, Rosen S, Axelrod J, and Heyman SN: Renal Hypoxia Inducible Factors (HIF)

and STAT3 Cross-Talk In Vivo. The American Society of Nephrology (ASN) conference,

San Diego, California, 2009. (Talk).

20. Bursztyn M, Skarzinski G, Ariel I, Mekler J, Khamaisi M: Hyperinsulinemia

Increases Placenta Endothelin Converting Enzyme -1 Expression in Trophoblasts. The

18

Second Annual Meeting of the Israeli Society for Placenta Research, Weizmann Institute

of Science, Rehovot, 16th Spet. 2010. (Talk).

21. Bursztyn M, Skarzinski G, Ariel I, Azran F, Mekler J, Khamaisi M:Hyperinsulinemia

increases placenta endothelin converting enzyme-1 expression in trophoblasts. The High

Blood Pressure Research Conference, Washington, DC, Oct 2010 (Poster).

22. Granovsky Y, Nahman-Averbuch H, Granot M, Khamaisi M, Yarnitsky D.

Less efficient conditioned pain modulated pain modulation associated with greater pain

relief to duloxetine among neuropathic pain patients. The 7th

congress of the International

Association for the Study of Pain. Hamburg, September 2011.

23. Khamaisi M, Mimura I, Toukan H, Axelrod JH, Rosenberger C, Skarzinski G, Shina

A, Koesters R, Walkinshaw G, Rosen S, Nangaku M, Heyman SN. Endothelin converting

enzyme (ECE)-1: a plausible target gene for hypoxia inducible factor (HIF). The American

Society of Nephrology annually meeting, San Diego, November 2012 (Poster).

24. Khamaisi M, Wu IH, Hastings S, Keenan HA, King GL. Characterization of

persistent defects in insulin activation, migration, and VEGF production in fibroblast from

type 1 diabetic patients of extreme duration. The 73th annually conference of the

American Diabetes Association (ADA), Chicago, June 2013.

25. Khamaisi M, Rosenberger C, Toukan H, Shina A, Skarjinski G, Axelrod J,

Abramowitz R, Millman Z, Rosen S, Mimura I, Nangaku, Heyman SN. On Renal Hypoxia,

Cyclosporine and Edothelin Converting Enzyme (ECE)-1. The Israeli Society of

Nephrology and Hypertension, Tel-Aviv, April 2013.

26. Naccache DD, Hershkovits M, Nsseir W, Khamaisi M. Diabetic Neuropathic

Cachexia: Challenges and Priorities of Clinical Practice; A case report. The Israeli

Endocrine Society annually conference, Tel-Aviv, April 2013.

27. Abu-saleh N, Khamaisi M, Awad H, Assady S, Cohen R, Armaly Z, Abassi Z.

Involvement of Nitric Oxide and Endothelin Systems in the Pathogenesis of Endothelial

Dysfunction in Diabetic Nephropathy. American Society of Nephrology Kidney Week

2013, November 5-10, Atlanta, USA. (Talk).

28. Abu-saleh N, Awad H, Khamaisi M, Cohen R, Heyman SN, Armaly Z, Abassi Z.

Nephroprotective Effects of TVP1022 in Experimental Model of Diabetic Renal Ischemic

Injury. American Society of Nephrology Kidney Week 2013, November 5-10, Atlanta,

USA. (Poster).

29. Khamaisi M, Wu IH, Katagiri S, Hastings H, Keenan HA, Orgill DP, KING GL.

Persistent Activation of PKC And Inhibition of Insulin Actions in Fibroblasts from Type

1 Diabetes with CVD Impaired Wound Healing. The 74th annually conference of the

American Diabetes Association (ADA), San Francisco, June 2014.

19

30. Katagiri S, Maeda Y, Park K, Li Q, Khamaisi M, Lancerotto L, Orgill DP, King GL.

Demonstration of insulin’s critical rolein angioblasts formation and re-vascularization in

wound healing with and without diabetes. The 74th annually conference of the American

Diabetes Association (ADA), San Francisco, June 2014.

31. Keenan, HA, Fitzgerald, S, He ZH, Hastings SM, Sun JK, Khamaisi, M, King GL.

Differential Factors for Diabetic Nephropathy and Retinopathy. The 74th annually

conference of the American Diabetes Association (ADA), San Francisco, June 2014.

32. Peer A, Molcho S, Berg T, Futerman B, and Khamaisi M. Diabetes Microvascular

Disease and the Risk for Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ).

Israeli society for clinical oncology and radiation therapy (ISCORT), 13 annual

meeting, Eilat, Israel, Jan 2013,

33. Budron M, Khamaisi M, King GL. Characterization of Human iPS Cells to

Endothelial cells. DePaul Symposium on Chicago University, November 2013.

34. Keenan HA, Fitzgerald S, Khamaisi M, Turek SJ, Hastings SM, King GL, Bouxsein,

ML. Protection from Fracture Risk in Long Term Type 1 Diabetes: 50- Year Medalist

Study

35. Ramirez L, Khamaisi M, King GL. Characterization of iPS cells for Wound Healing

in Diabetic Patients. NIDDK Medical Student Research Symposium, Vanderbilt

University, Nashville TN, August 2014.

36. Granovsky Y, Nahman-Averbuch H, Khamaisi M, Yarnitsky D, Granot M. Pro-

Nociceptive pattern of pain modulation characterizes patients with painful diabetic

neuropathy. Yom Mehkar, Rambam Health Care Campus, Haifa, Israel, November 2014.

45. Khamaisi M, Keenan HA, Park K, Qi W, Li Q, Yasutaka M, Maddaloni E, and King

FL. Abnormal Insulin Signaling and Actions Persisted in Stem Cells and Fibroblasts from

Type 1 Diabetic Patients of Chronic Duration. The 75th annually conference of the

American Diabetes Association (ADA), Boston, June 2015.

46. Pober D*, Khamaisi M*,Hastings S, D’Eon S, Tinsley L, King GL, and Keenan HA:

Lower Mortality in Insulin Pump Users with Type 1 Diabetes of Chronic Duration. The

75th annually conference of the American Diabetes Association (ADA), Boston, June

2015.

47. Maddaloni E, Hernandez SL, Khamaisi M, King GL, and Keenan HA. Correlation of

Circulating Endothelial Progenitor Cells to Preservation of Glomerular Filtration Rate in

Type 1 Diabetes of Chronic Duration. The 75th annually conference of the American

Diabetes Association (ADA), Boston, June 2015.

48. Qian L, Weier QI, Kyoungmin P, Khamaisi M, and King GL. Differential outcome of

restenosis and atherosclerosis in mice with deletion of inulin receptor in vascular smooth

20

muscle cells. The 75th annually conference of the American Diabetes Association (ADA),

Boston, June 2015.

49. Kyoungmin P, Qian L, Khamaisi M, Evcimen N, Rask-Madsen C, and King GL.

Reduction of atherosclerosis by exogenous-induced hyperinsulinemia in high fat diet

induced insulin resistance and diabetes in apolipoprotein in E-/- mice. The 75th annually

conference of the American Diabetes Association (ADA), Boston, June 2015.

50. Maeda Y, Hernandez S, Sun B, Kyoungmin P, Katagiri S, Khamaisi M, Ishikado A,

Clemont A, Hastings S, Avery R, Feener E, Sun JK, Aiello LP, Kern TS, Keenan HA,

King GL. Identification of retinol-binding protein 3 (RBP3): A protective factor against

diabetic retinopathy using retina from people with extreme duration of diabetes. The 75th

annually conference of the American Diabetes Association (ADA), Boston, June 2015.

51. Qi W, Qian L, Liew CW, Khamaisi M, Rasmussen LM, Rask-Madsen C, Croce K,

King GL. Novel regulatory role of SHP1 on the inflammatory response in VSMC and

restenosis in insulin resistance and diabetes. The 75th annually conference of the

American Diabetes Association (ADA), Boston, June 2015.

52. Maeda Y, Ishikado A, Kyoungmin P, Khamaisi M, Qi W, Hasting S, Pober D,

Keenan HA, Stillman IE, King GL. Characterization of podocyte dipeptidyl peptidase-4

expression in glomeruli after 50years of diabetes. The 75th annually conference of the

American Diabetes Association (ADA), Boston, June 2015.

53. Keenan HA, Tinsley L, D’eon S, Hastings S, Khamaisi M, Sun JK, King GL. After

50 years, C-peptide does not protect from diabetic neuropathy. The 75th annually

conference of the American Diabetes Association (ADA), Boston, June 2015.

54. Keenan H, D'Eon S, Hastings S, Khamaisi M, King G, Pober D, Sun J, Tinsley L.

Protection from diabetic retinopathy, but not nephropathy. The 51th

annual meeting of the

European Association for the Study of Diabetes, Stockholm, Sweden, 2015.

15. SPECIAL PROFESSIONAL ACTIVITIES

2005-2008 Member of admission committee, School of Medicine, Hebrew

University, Jerusalem, Israel.

21

2009-to date Member in the admission committee, Rappaport Faculty of

Medicine, Technion, Israel

16. Invited seminar presentations at Universities and Institutions:

2007 Institute of Endocrinology, Metabolism and Hypertension, Sourasky

Medical Center, Tel Aviv, Israel.

2007 Endocrine seminar for post graduate students, Department of

Pharmacology, Technion, Israel Institute of Technology, Haifa, Israel.

2009 Endocrine seminar for post graduate students, Department of

Pharmacology, Technion, Israel Institute of Technology, Haifa, Israel.

2011 Joslin Diabetes Center, Harvard Medical School, Boston, MA.

2016 Institute of Endocrinology, Metabolism and Hypertension, Sourasky

Medical Center, Tel Aviv, Israel.

17. Invited talks in scientific meetings:

- The 4th

Russell Berrie International Diabetes Symposium, Tel Aviv, Israel, March

2009.

- A Multi-disciplinary Scientific Meeting on Bisphosphonate Induced Osteonecrosis

of the Jaws (ONJ): Pathophysiological and Clinical Aspects. Haifa, Israel, June

2009.

- The annually Israel Diabetes association conference, Tel Aviv, Israel, Jun 2009.

- The 39th Annual conference of the Israel Endocrine Society, Airport city, April

2010.

- The 46th

Annual conference of the Israeli Society of Nephrology and Hypertension,

Kfar Bloom, April 2010.

- A Multi-disciplinary Scientific Meeting on diabetes and obesity in the Israeli Arab

population. Nazareth, Israel, April 2011.

- Wyss Annual Diabetes Symposium: Lower Extremity Innovations and Discovery,

Harvard Medical School, Boston, March 2015.

22

- 2015 Latin American conference on cardio metabolic diseases management.

Lecture title" Cardiometabolic implications of thyroid dysfunction". 3-4 July,

2015, Huatulco, Mexico

- 2016 Asia Pacific conference on cardiometabolic diseases management. Lecture

title" The role of insulin resistance in the development of vascular complications".

23-24 April 2016, Ho Chi Minh, Vietnam

- 2016 The 45th Annual Meeting of The Israeli Endocrine Society. Lecture title"

What is New in Diabetic Wound Treatment: A Potential Use of Human Inducible

Stem Cells, April 12-14, Jerusalem, Israel