1) ethanol 2) ethane -...
TRANSCRIPT
Complete combustion of
which produces more energy?
1) Ethanol
2) Ethane
H2C CH3
H2C C
H2
OH
H2C C
O
H2C C
O
OH
H
C OO
R
R
R
R
R CH3
More
oxid
ized
2.5C C
H
H
H
2.1
2.1
2.1
C C
O
H
H
H
2.5
3.5
2.1
2.12.5
C C
O
H2.5
2.1
3.5
C C
O
O H2.5
3.5
3.5
2.5
2.5
2.5
C OO2.5
3.53.5
H2C CH3
H2C C
H2
OH
H2C C
O
H2C C
O
OH
H
C OO
R
R
R
R
R CH3
More
oxid
ized
-1561 k
J/m
ol
-1368 k
J/m
ol
-1167 k
J/m
ol
-875 k
J/m
ol
Heats of combustion (R=H)
xx + mO2 2CO2 + nH2O
Which reaction ismost favorable?
P
O
P
O O
OH
P
O
O
OH
P
O
OH
P
HO
P
O O
O
P
HO
O
O
P
O
O
1)
2)
3)
-O-O
-O
-O -O
-O
-O -O
Which reaction ismost favorable?
P
O
P
O O
OH
P
O
O
OH
P
O
OH
P
HO
P
O O
O
P
HO
O
O
P
O
O
1)
2)
3)
-O-O
-O
-O -O
-O
-O -O
ATP - can “phosphorylate” alchohols
-O
P
O
P
O O
OH
R
-O
P
O
O
R
-O-O
-O
O
P
O-O
N
NN
N
NH2
O
HOH
HH
HH
O
-O
P
O-O
O
P
O-O
N
NN
N
NH2
O
HOH
HH
HH
O
ATP - hydrolysis VERY favorable
-O
P
O
P
O O
H2O
-O-O
O
P
O-O
N
NN
N
NH2
O
HOH
HH
HH
O
-O
P
O
P
O O-O
-O
-O
P
O-O
N
NN
N
NH2
O
HOH
HH
HH
OO-
ATP - Two uses
Phosphorylate things
Hydrolysis coupled to unfavorable reactions
Oh, and it’s a part of RNA and DNA
Coenzyme A(not an enzyme)
O
P
O-O
O
P
O-O
N
NN
N
NH2
O
HOH
HH
HH
O
HN
HN
HS
OH
OO
Coenzyme A(not an enzyme)
O
P
O-O
O
P
O-O
N
NN
N
NH2
O
HOH
HH
HH
O
HN
HN
HS
OH
OO
O
P
O-O
O
P
O-O
N
NN
N
NH2
O
HOH
HH
HH
O
HN
HN
S
OH
OO
O
O
O
R
R
OH
Acetyl CoA
HS-CoA
Glycolysis
Combustion (“burning”) of sugars (carbohydrates)
G°’ (kJ/mol) (kcal/mol)
Activate
Isomerize
Cleave C-C
Activate
Oxidize and
phosphorylate
Phospho-
anhydride is
High Energy
Transfer P
to ADP
Intramolec
xfer of P
Dehydrate
enol ester
Transfer P
to ADP
This time,
reaction of 1,3-bisphosphoglycerate to
3-phosphoglycerate is more favorable
than hydrolysis of ATP
So the reaction drives hydrolysis
backwards - makes ATP from ADP
Energy has been STORED.
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