1. coronary artery flow towards the heart should be lamiar contrary artery are hidden deep within...

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Visual flow characteristics of plaque accumulation in diseased coronary artery Bryan M. Gonzales Undergrad Chemistry Major Grad year: May 2014 Grad Interest :PhD. Inorganic Chemistry Mentor: Dr. Bhaganagar and Carlos Moreno 1

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Page 1: 1. Coronary artery  Flow towards the heart  Should be lamiar  Contrary artery are hidden deep within chest, constantly moving and 5mm in length Diseased

Visual flow characteristics of plaque accumulation in diseased coronary artery

Bryan M. GonzalesUndergrad Chemistry MajorGrad year: May 2014Grad Interest :PhD. Inorganic Chemistry Mentor: Dr. Bhaganagar and Carlos Moreno

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Page 2: 1. Coronary artery  Flow towards the heart  Should be lamiar  Contrary artery are hidden deep within chest, constantly moving and 5mm in length Diseased

Coronary artery Flow towards the heart Should be lamiar Contrary artery are hidden deep within

chest, constantly moving and 5mm in length

Diseased coronary artery• Is the plaque build up inside the coronary

arteries • Block flow leads to blood clots causing

heart attacks• Percentage stenosis relates condition

Flow characteristics in contrary artery

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Page 3: 1. Coronary artery  Flow towards the heart  Should be lamiar  Contrary artery are hidden deep within chest, constantly moving and 5mm in length Diseased

Use and understand fluid flow patterns in relation with diseased coronary arteries.

Construct 3D model types of plaque buildup Type I Bump Type II Rising climb Type III Normal

Graphs and simulators will show the pulsating nature of the 3 buildup types

Objective

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Page 4: 1. Coronary artery  Flow towards the heart  Should be lamiar  Contrary artery are hidden deep within chest, constantly moving and 5mm in length Diseased

Problem:How does the height of the stenosis effected the flow patterns and pressure differences?

Significance:Observations and research data can characterize the effects of plaques buildup base on the flow in coronary artery and understand factors of turbulence.

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Page 5: 1. Coronary artery  Flow towards the heart  Should be lamiar  Contrary artery are hidden deep within chest, constantly moving and 5mm in length Diseased

Constructing 3d models and classify them by three 3 types of plaque accumulation (bump, rising, and normal flow) using solid works programing

Preforming flow simulations with ANSYS programing

Generate 3D contour graphs with visual turbulences patterns.

Methodologies

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Page 6: 1. Coronary artery  Flow towards the heart  Should be lamiar  Contrary artery are hidden deep within chest, constantly moving and 5mm in length Diseased

Type 1(bump) plaque buildup

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Page 7: 1. Coronary artery  Flow towards the heart  Should be lamiar  Contrary artery are hidden deep within chest, constantly moving and 5mm in length Diseased

What have I completed to data? Collect of data, 3d model, velocity and turbulence plots

What more do I need to do? Working with ANSYS programing to generate detail simulations

What do you expect to present at the end of the summer? Visual simulations of plaque types and effects of turbulences, 3D model of artery

What unexpected problems have you encountered? Working with engineer programing and mathematical functions

What advice would you give to others who embark on the summer program? Revise your work and methods, make an effort to attend lab every day and work with your

mentor. How has the project changed your perception of research and possible

graduate school or career pursuit? Gives first hand experiences and a insight of what to expect on the next level improving

research. Other comments about the project?

Fluid dynamics can be useful in understanding the vapor pressure of gases and liquids

Progress Report

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