Research outputsListing of Research outputs

Genetic and Inflammatory Biomarkers Classify Small Intestine Inflammation in Asymptomatic First-degree Relatives of Patients With Crohn's DiseaseTaylor, K. M., Hanscombe, K. B., Prescott, N. J., Iniesta, R., Traylor, M., Taylor, N. S., Fong, S., Powell, N., Irving, P. M., Anderson, S. H., Mathew, C. G., Lewis, C. M. & Sanderson, J. D., 14 Jun 2019, In : Clinical Gastroenterology and Hepatology : the official clinical practice journal of the American Gastroenterological Association.Research output: Contribution to journal › Article

Prevalence of Advanced Liver Fibrosis in Patients With Severe PsoriasisMaybury, C. M., Porter, H. F., Kloczko, E., Duckworth, M., Cotton, A., Thornberry, K., Dew, T., Crook, M., Natas, S., Miquel, R., Lewis, C. M., Wong, T., Smith, C. H. & Barker, J. N., 5 Jun 2019, In : JAMA dermatology.Research output: Contribution to journal › Article

UKBTools: An R package to manage and query UK Biobank dataHanscombe, K. B., Coleman, J. R. I., Traylor, M. & Lewis, C. M., 31 May 2019, In : PLoS ONE. 14, 5, p. 1-6 6 p., e0214311.Research output: Contribution to journal › Article

Genome-wide survey of copy number variants finds MAPT duplications in progressive supranuclear palsyNNIPPS and BBBIPPS Study Groups, 6 May 2019, In : Movement Disorders.Research output: Contribution to journal › Article

Evidence of causal effect of major depression on alcohol dependence: Findings from the psychiatric genomics consortiumPolimanti, R., Peterson, R. E., Ong, J. S., MacGregor, S., Edwards, A. C., Clarke, T. K., Frank, J., Gerring, Z., Gillespie, N. A., Lind, P. A., Maes, H. H., Martin, N. G., Mbarek, H., Medland, S. E., Streit, F., Agrawal, A., Edenberg, H. J., Kendler, K. S., Lewis, C. M., Sullivan, P. F. & 3 othersWray, N. R., Gelernter, J. & Derks, E. M., 1 May 2019, In : Psychological Medicine. 49, 7, p. 1218-1226 9 p.Research output: Contribution to journal › Article

Progressing Polygenic Medicine in Psychiatry Through Electronic Health RecordsLewis, C. M. & Hagenaars, S. P., 1 May 2019, In : JAMA Psychiatry. 76, 5, p. 470-472 3 p.Research output: Contribution to journal › Editorial

The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control studyEU-GEI WP2 Group, 1 May 2019, In : The Lancet Psychiatry. 6, 5, p. 427-436 10 p.Research output: Contribution to journal › Article

Polygenic risk for circulating reproductive hormone levels and their influence on hippocampal volume and depression susceptibilitySmeeth, D. M., Dima, D., Jones, L., Jones, I., Craddock, N., Owen, M. J., Rietschel, M., Maier, W., Korszun, A., Rice, J. P., Mors, O., Preisig, M., Uher, R., Lewis, C. M., Thuret, S. & Powell, T. R., 20 Apr 2019, In : Psychoneuroendocrinology. 106, p. 284-292 9 p.Research output: Contribution to journal › Article

Uncovering the Genetic Architecture of Major DepressionMcIntosh, A. M., Sullivan, P. F. & Lewis, C. M., 3 Apr 2019, In : Neuron. 102, 1, p. 91-103 13 p.Research output: Contribution to journal › Review article

Genome-wide association study identifies 30 Loci Associated with Bipolar DisorderStahl, E. A., Breen, G. D., Coleman, J. R. I., Lewis, C. M. & Sklar, P., 18 Mar 2019, (Accepted/In press) In : Nature Genetics.Research output: Contribution to journal › Article

Genome-wide burden of rare short deletions is enriched in Major Depressive Disorder in four cohortsZhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L., McGuffin, P. & 13 othersMors, O., Owen, M. J., Preisig, M., Rietschel, M., Rice, J. P., Rivera, M., Uher, R., Gejman, P. V., Sanders, A. R., Boomsma, D., Penninx, B. W. J. H., Breen, G. & Levinson, D. F., 13 Mar 2019, In : Biological psychiatry.Research output: Contribution to journal › Article

Transforming Summary Statistics from Logistic Regression to the Liability Scale: Application to Genetic and Environmental Risk ScoresGillett, A. C., Vassos, E. & Lewis, C. M., 13 Mar 2019, In : Human Heredity. 83, 4, p. 210-224 15 p.Research output: Contribution to journal › Article

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regionsHoward, D. M., Adams, M. J., Clarke, T., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., Wigmore, E. M., Alloza, C., Shen, X., Barbu, M. C., Xu, E. Y., Whalley, H. C., Marioni, R. E., Porteous, D. J., Davies, G., Deary, I. J., Hemani, G. & 18 othersBerger, K., Teismann, H., Rawal, R., Arolt, V., Baune, B. T., Dannlowski, U., Domschke, K., Tian, C., Hinds, D. A., Trzaskowski, M., Byrne, E. M., Ripke, S., Smith, D. J., Sullivan, P. F., Wray, N. R., Breen, G., Lewis, C. M. & Mcintosh, A. M., Mar 2019, In : Nature Neuroscience. 22, 3, p. 343-352 10 p.Research output: Contribution to journal › Article

Association of genetic variants in CHEK2 with oesophageal squamous cell carcinoma in the South African Black populationChen, W. C., Bye, H., Matejcic, M., Amar, A., Govender, D., Khew, Y. W., Beynon, V., Kerr, R., Singh, E., Prescott, N. J., Lewis, C. M., Babb de Villiers, C., Parker, M. I. & Mathew, C. G., 12 Feb 2019, In : Carcinogenesis.Research output: Contribution to journal › Article

Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scoresMullins, N. A., Coleman, J. R. I., Breen, G. D. & Lewis, C. M., 4 Feb 2019, (Accepted/In press) In : The American Journal of Psychiatry.Research output: Contribution to journal › Article

Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorderMajor Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Feb 2019, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics.Research output: Contribution to journal › Article

Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEPWigmore, E. M., Hafferty, J. D., Hall, L. S., Howard, D. M., Clarke, T-K., Fabbri, C., Lewis, C. M., Uher, R., Navrady, L. B., Adams, M. J., Zeng, Y., Campbell, A., Gibson, J., Thomson, P. A., Hayward, C., Smith, B. H., Hocking, L. J., Padmanabhan, S., Deary, I. J., Porteous, D. J. & 4 othersMors, O., Mattheisen, M., Nicodemus, K. K. & McIntosh, A. M., 31 Jan 2019, In : The pharmacogenomics journal.Research output: Contribution to journal › Article

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorderGeneration Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J. R. I., Eley, T. C., Gaspar, H. A., McGuffin, P., Mullins, N., O'Reilly, P. F., Lewis, C. M. & Breen, G., 20 Dec 2018, In : PLoS ONE. 13, 12, e0209160.Research output: Contribution to journal › Article

The polygenic nature of telomere length and the anti-ageing properties of lithiumCoutts, F., Palmos, A. B., Duarte, R. R. R., de Jong, S., Lewis, C. M., Dima, D. & Powell, T. R., 18 Dec 2018, In : Neuropsychopharmacology.Research output: Contribution to journal › Article

Telomere length as a predictor of emotional processing in the brainPowell, T. R., De Jong, S., Breen, G., Lewis, C. M. & Dima, D., 4 Dec 2018, In : Human Brain Mapping.Research output: Contribution to journal › Article

Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP)Ren, H., Fabbri, C., Uher, R., Rietschel, M., Mors, O., Henigsberg, N., Hauser, J., Zobel, A., Maier, W., Dernovsek, M. Z., Souery, D., Cattaneo, A., Breen, G., Craig, I. W., Farmer, A. E., McGuffin, P., Lewis, C. M. & Aitchison, K. J., 1 Dec 2018, In : Translational psychiatry. 8, 1, 150.Research output: Contribution to journal › Article

Genome-wide association study of treatment-resistance in depression and meta-analysis of three independent samplesFabbri, C., Kasper, S., Kautzky, A., Bartova, L., Dold, M., Zohar, J., Souery, D., Montgomery, S., Albani, D., Raimondi, I., Dikeos, D., Rujescu, D., Uher, R., Lewis, C. M., Mendlewicz, J. & Serretti, A., 23 Nov 2018, In : British Journal of Psychiatry. 214, 1, p. 36-41Research output: Contribution to journal › Article

Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disordersO'Brien, H. E., Hannon, E., Hill, M. J., Toste, C. C., Robertson, M. J., Morgan, J. E., McLaughlin, G., Lewis, C. M., Schalkwyk, L. C., Hall, L. S., Pardiñas, A. F., Owen, M. J., O'Donovan, M. C., Mill, J. & Bray, N. J., 12 Nov 2018, In : Genome Biology. 19, 1, 1 p.Research output: Contribution to journal › Article

Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African AmericansHanscombe, K. B., Morris, D. L., Noble, J. A., Dilthey, A. T., Tombleson, P., Kaufman, K. M., Comeau, M., Langefeld, C. D., Alarcon-Riquelme, M. E., Gaffney, P. M., Jacob, C. O., Sivils, K. L., Tsao, B. P., Alarcon, G. S., Brown, E. E., Croker, J., Edberg, J., Gilkeson, G., James, J. A., Kamen, D. L. & 16 othersKelly, J. A., McCune, J., Merrill, J. T., Petri, M., Ramsey-Goldman, R., Reveille, J. D., Salmon, J. E., Scofield, H., Utset, T., Wallace, D. J., Weisman, M. H., Kimberly, R. P., Harley, J. B., Lewis, C. M., Criswell, L. A. & Vyse, T. J., 1 Nov 2018, In : Human Molecular Genetics. 27, 21, p. 3813-3824 12 p., 27(21).Research output: Contribution to journal › Article

Genetic risk for psychiatric disorders and telomere lengthPalmos, A. B., Breen, G., Goodwin, L., Frissa, S., Hatch, S. L., Hotopf, M., Thuret, S., Lewis, C. M. & Powell, T. R., 16 Oct 2018, In : Frontiers in Genetics. 9, OCT, 468.Research output: Contribution to journal › Article

Transdiagnostic dimensions of psychopathology at first episode psychosis: findings from the multinational EU-GEI studyQuattrone, D., Di Forti, M., Gayer-Anderson, C., Ferraro, L., Jongsma, H. E., Tripoli, G., La Cascia, C., La Barbera, D., Tarricone, I., Berardi, D., EU-GEI WP2 Group, Szöke, A., Arango, C., Lasalvia, A., Tortelli, A., Llorca, P-M., de Haan, L., Velthorst, E., Bobes, J., Bernardo, M. & 18 othersSanjuán, J., Santos, J. L., Arrojo, M., Del-Ben, C. M., Menezes, P. R., Selten, J-P., Jones, P. B., Kirkbride, J. B., Richards, A. L., O'Donovan, M. C., Sham, P. C., Vassos, E., Rutten, B. P., van Os, J., Morgan, C., Lewis, C. M., Murray, R. M. & Reininghaus, U., 4 Oct 2018, In : Psychological Medicine. p. 1-14 14 p.Research output: Contribution to journal › Article

Conference Report: Psychiatric Genomics Consortium Meeting: Pathways to Drugs, London, March 2017Gaspar, H. A., Collier, D. A., Geschwind, D. H., Lewis, C. M., Li, Q., Roth, B. L., Sullivan, P. F. & Breen, G., 15 Sep 2018, In : Biological psychiatry. 84, 6, p. e49-e50Research output: Contribution to journal › Article

Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disordersGenetic Risk and Outcome of Psychosis (GROUP) consortium, Sep 2018, In : The British journal of psychiatry : the journal of mental science. 213, 3, p. 535-541 7 p.Research output: Contribution to journal › Article

Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseasesChen, J. A., Chen, Z., Won, H., Huang, A. Y., Lowe, J. K., Wojta, K., Yokoyama, J. S., Bensimon, G., Leigh, P. N., Payan, C., Shatunov, A., Jones, A. R., Lewis, C. M., Deloukas, P., Amouyel, P., Tzourio, C., Dartigues, J. F., Ludolph, A., Boxer, A. L., Bronstein, J. M. & 3 othersAl-Chalabi, A., Geschwind, D. H. & Coppola, G., 8 Aug 2018, In : Molecular Neurodegeneration. 13, 1, 41.Research output: Contribution to journal › Article

Genetic disposition to inflammation and response to antidepressants in major depressive disorderZwicker, A., Fabbri, C., Rietschel, M., Hauser, J., Mors, O., Maier, W., Zobel, A., Farmer, A., Aitchison, K. J., McGuffin, P., Lewis, C. M. & Uher, R., 7 Aug 2018, In : Journal of psychiatric research.Research output: Contribution to journal › Article

Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studiesFabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Lee, S-H., Newhouse, S., Patel, H., O'Donovan, M., Lewis, G., Jenkins, G., Weinshilboum, R. M., Farmer, A. & 7 othersAitchison, K. J., Craig, I., McGuffin, P., Schruers, K., Biernacka, J. M., Uher, R. & Lewis, C. M., 28 Jun 2018, In : European Neuropsychopharmacology.Research output: Contribution to journal › Article

DNA methylation and inflammation marker profiles associated with a history of depressionCrawford, B., Craig, Z., Mansell, G., White, I., Smith, A., Spaull, S., Imm, J., Hannon, E., Wood, A., Yaghootkar, H., Ji, Y., Mullins, N., Lewis, C. M., Mill, J. & Murphy, T. M., 22 May 2018, In : Human Molecular Genetics. 27, 16, p. 2840-2850 11 p.Research output: Contribution to journal › Article

New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputationFabbri, C., Tansey, K., Perlis, R., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 othersBiernacka, J., Weinshilboum, R., Farmer, A., Aitchison, K., Craig, I., McGuffin, P., Uher, R. & Lewis, C., 22 May 2018, In : The pharmacogenomics journal. 18, p. 413-421Research output: Contribution to journal › Article

Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancerTraylor, M., Walker, J. L., Corrigan, A. A., Hernandez, M. A., Newhouse, S. J., Folarin, A. A., Patel, H., Ross, P. J., Sanderson, J. D., Spicer, J., Prescott, N. J., Mathew, C. G., Marinaki, A. M. & Lewis, C. M., 1 May 2018, In : PLoS ONE. 13, 5, 11 p., e0188911.Research output: Contribution to journal › Article

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressionThe Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S., Bækvad-hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-grauholm, J. & 32 othersCai, N., Castelao, E., Christensen, J. H., Clarke, T., Coleman, J. I. R., Colodro-conde, L., Couvy-duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Eley, T. C., Gaspar, H. A., Hansen, T. F., Li, Y., Mcguffin, P., Mill, J., Mullins, N., Purcell, S. M., Riley, B. P., Smith, D. J., Tansey, K. E., Traylor, M., Uher, R., Lewis, C. M., Breen, G. & O'Reilly, P. F., 1 May 2018, In : Nature Genetics. 50, 5, p. 668-681Research output: Contribution to journal › Article

Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathwaysHoward, D. M., Adams, M. J., Shirali, M., Clarke, T. K., Marioni, R. E., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X., Barbu, M. C., Wigmore, E. M., Gibson, J., Hagenaars, S. P., Lewis, C. M., Ward, J., Smith, D. J., Sullivan, P. F., Haley, C. S., Breen, G., Deary, I. J. & 1 othersMcIntosh, A. M., 16 Apr 2018, In : Nature Communications. 9, 1, p. 1-3 1 p.Research output: Contribution to journal › Article

Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variablesIniesta, R., Hodgson, K., Stahl, D. R., Malki, K., Maier, W., Rietschel, M., Mors, O., Hauser, J., Henigsberg, N., Dernovšek, M. Z., Souery, D., Dobson, R. M., Aitchison, K. J., Farmer, A. E., McGuffin, P., Lewis, C. M. & Uher, R., 3 Apr 2018, In : Scientific Reports.Research output: Contribution to journal › Article

116 independent genetic variants influence the neuroticism personality trait in over 329,000 UK Biobank individualsLuciano, M., Hagenaars, S. P., Lewis, C. M. & Deary, I., Jan 2018, In : Nature Genetics.Research output: Contribution to journal › Article

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathwaysHoward, D. M., Adams, M. J., Shirali, M., Clarke, T-K., Marioni, R. E., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X., Barbu, M. C., Wigmore, E. M., Gibson, J., Hagenaars, S. P., Lewis, C. M., Ward, J., Smith, D. J., Sullivan, P. F., Haley, C. S., Breen, G., Deary, I. J. & 1 othersMcIntosh, A. M., 2018, In : Nature Communications. 9, 1, 1470.Research output: Contribution to journal › Article

Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic DysregulationsMilaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., Dehghan, A., Forstner, A. J., Grabe, H. J., Homuth, G., Kan, C., Lewis, C., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rivera, M., Rietschel, M., Streit, F., Strohmaier, J., Teumer, A. & 4 othersVan der Auwera, S., Wray, N. R., Boomsma, D. I. & Penninx, B. W. J. H., 1 Dec 2017, In : JAMA Psychiatry. 74, 12, p. 1214-1225 12 p.Research output: Contribution to journal › Article

New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputationFabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 othersBiernacka, J. M., Weinshilboum, R. M., Farmer, A., Aitchison, K. J., Craig, I., McGuffin, P., Uher, R. & Lewis, C. M., 21 Nov 2017, In : The pharmacogenomics journal.Research output: Contribution to journal › Article

Prospects for using risk scores in polygenic medicineLewis, C. M. & Vassos, E., 13 Nov 2017, In : Genome medicine. 9, 1, 3 p., 96.Research output: Contribution to journal › Comment/debate

Advancing psychiatric genetics through dissecting heterogeneityHodgson, K., McGuffin, P. & Lewis, C. M., 1 Oct 2017, In : Human Molecular Genetics. 26, R2, p. R160-R165Research output: Contribution to journal › Review article

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics ConsortiumPeyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C. V., Madden, P. AF., Sullivan, P. F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M. G., Mullins, N., Montgomery, G. W., Henders, A. K., Heat, A. C., Fisher, H. L., Dunn, E. C., Byrne, E. M., Air, T. A. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 21 Sep 2017, In : Biological psychiatry.Research output: Contribution to journal › Article

Interaction between childhood maltreatment on immunogenetic risk in depression: discovery and replication in clinical case-control samplesCohen-Woods, S., Fisher, H. L., Ahmetspahic, D., Douroudis, K., Stacey, D., Hosang, G. M., Korszun, A., Owen, M., Craddock, N., Arolt, V., Dannowski, U., Breen, G., Craig, I. W., Farmer, A., Baune, B. T., Lewis, C. M., Uher, R. & McGuffin, P., 1 Sep 2017, In : Brain, Behavior, and Immunity. 67, p. 203-210Research output: Contribution to journal › Article

A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domainsRanlund, S., Calafato, S., Thygesen, J. H., Lin, K., Cahn, W., Crespo-Facorro, B., de Zwarte, S. M. C., Díez, Á., Di Forti, M., Iyegbe, C., Jablensky, A., Jones, R., Hall, M. H., Kahn, R., Kalaydjieva, L., Kravariti, E., Mcdonald, C., Mcintosh, A. M., Mcquillin, A., Picchioni, M. & 13 othersPrata, D. P., Rujescu, D., Schulze, K., Shaikh, M., Toulopoulou, T., van Haren, N., van Os, J., Vassos, E., Walshe, M., Lewis, C., Murray, R. M., Powell, J. & Bramon, E., 29 Aug 2017, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 177, 1, p. 21-34Research output: Contribution to journal › Article

Genome-wide gene-environment interaction in depression: A systematic evaluation of candidate genes: The childhood trauma working-group of PGC-MDDVan der Auwera, S., Peyrot, W. J., Milaneschi, Y., Hertel, J., Baune, B., Breen, G., Byrne, E., Dunn, E. C., Fisher, H., Homuth, G., Levinson, D., Lewis, C., Mills, N., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rietschel, M., Ripke, S., Sullivan, P. & 6 othersTeumer, A., Völzke, H., Boomsma, D. I., Wray, N. R., Penninx, B. & Grabe, H., 8 Aug 2017, (Accepted/In press) In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 177, 1, p. 40-49Research output: Contribution to journal › Article

Genetic and environmental risk factors for rheumatoid arthritis in a UK African ancestry population: the GENRA case-control studyTraylor, M., Curtis, C., Patel, H., Breen, G., Hyuck Lee, S., Xu, X., Newhouse, S., Dobson, R., Steer, S., Cope, A. P., Markus, H. S., Lewis, C. M. & Scott, I. C., 1 Aug 2017, In : Rheumatology. 56, 8, p. 1282–1292Research output: Contribution to journal › Article

Interaction between the FTOgene, body mass index and depression: meta-analysis of 13701 individualsRivera, M., Locke, A. E., Corre, T., Czamara, D., Wolf, C., Ching-Lopez, A., Milaneschi, Y., Kloiber, S., Cohen-Woods, S., Rucker, J., Aitchison, K. J., Bergmann, S., Boomsma, D. I., Craddock, N., Gill, M., Holsboer, F., Hottenga, J-J., Korszun, A., Kutalik, Z., Lucae, S. & 18 othersMaier, W., Mors, O., Müller-Myhsok, B., Owen, M. J., Penninx, B. W. J. H., Preisig, M., Rice, J., Rietschel, M., Tozzi, F., Uher, R., Vollenweider, P., Waeber, G., Willemsen, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Breen, G. & McGuffin, P., 1 Aug 2017, In : British Journal of Psychiatry. 211, 2, p. 70-76 7 p.Research output: Contribution to journal › Article

Validating a two-dimensional bipolar spectrum model integrating DSM-5's mixed features specifier for Major Depressive DisorderFerentinos, P., Fountoulakis, K. N., Lewis, C. M., Porichi, E., Dikeos, D., Papageorgiou, C. & Douzenis, A., 1 Aug 2017, In : Comprehensive Psychiatry. 77, p. 89-99 11 p.Research output: Contribution to journal › Article

Genetics of Depression: Progress at LastMullins, N. & Lewis, C. M., Aug 2017, In : CURRENT PSYCHIATRY REPORTS. 19, 8, p. 1-7 43.Research output: Contribution to journal › Article

The Relationship Between Mental Health, Disease Severity, and Genetic Risk for Depression in Early Rheumatoid ArthritisEuesden, J., Matcham, F., Hotopf, M., Steer, S., Cope, A. P., Lewis, C. M. & Scott, I. C., Jul 2017, In : Psychosomatic Medicine. 79, 6, p. 638-645Research output: Contribution to journal › Article

Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individualsRivera, M., Locke, A. E., Corre, T., Czamara, D., Wolf, C., Ching-Lopez, A., Milaneschi, Y., Kloiber, S., Cohen-Woods, S., Rucker, J., Aitchison, K. J., Bergmann, S., Boomsma, D. I., Craddock, N., Gill, M., Holsboer, F., Hottenga, J-J., Korszun, A., Kutalik, Z., Lucae, S. & 18 othersMaier, W., Mors, O., Müller-Myhsok, B., Owen, M. J., Penninx, B. W. J. H., Preisig, M., Rice, J., Rietschel, M., Tozzi, F., Uher, R., Vollenweider, P., Waeber, G., Willemsen, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Breen, G. & McGuffin, P., 22 Jun 2017, In : The British journal of psychiatry : the journal of mental science.Research output: Contribution to journal › Article

Pharmacogenetic testing through the direct-to-consumer genetic testing company 23andMeLu, M., Lewis, C. M. & Traylor, M., 19 Jun 2017, In : BMC GENOMICS. 1, 1Research output: Contribution to journal › Article

Cost-effectiveness of pharmacogenetic-guided treatment: are we there yet?Verbelen, M., Weale, M. E. & Lewis, C. M., 13 Jun 2017, In : The pharmacogenomics journal. 17, 5, p. 395-402Research output: Contribution to journal › Article

MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genesLopez, J. P., Fiori, L. M., Cruceanu, C., Lin, R., Labonte, B., Cates, H. M., Heller, E. A., Vialou, V., Ku, S. M., Gerald, C., Han, M-H., Foster, J., Frey, B. N., Soares, C. N., Müller, D. J., Farzan, F., Leri, F., MacQueen, G. M., Feilotter, H., Tyryshkin, K. & 16 othersEvans, K. R., Giacobbe, P., Blier, P., Lam, R. W., Milev, R., Parikh, S. V., Rotzinger, S., Strother, S. C., Lewis, C. M., Aitchison, K. J., Wittenberg, G. M., Mechawar, N., Nestler, E. J., Uher, R., Kennedy, S. H. & Turecki, G., 22 May 2017, In : Nature Communications. 8, 15497.Research output: Contribution to journal › Article

Pharmacogenetics of antidepressant response: A polygenic approach Major Depressive Disorder Working Group of the Psychiatric Genomic Consortium, 3 Apr 2017, In : Progress in Neuro-Psychopharmacology & Biological Psychiatry. 75, p. 128-134 7 p.Research output: Contribution to journal › Article

Genetics of stroke in a UK African ancestry case-control study: South London Ethnicity and Stroke StudyTraylor, M., Rutten-Jacobs, L., Curtis, C., Patel, H., Breen, G., Newhouse, S., Lewis, C. M. & Markus, H. S., Apr 2017, In : Neurol Genet. 3, 2, p. e142Research output: Contribution to journal › Article

Genetic effects influencing risk for major depressive disorder in China and EuropeBigdeli, T. B., Ripke, S., Peterson, R. E., Trzaskowski, M., Bacanu, S-A., Abdellaoui, A., Andlauer, T. F. M., Beekman, A. T. F., Berger, K., Blackwood, D. H. R., Boomsma, D. I., Breen, G., Buttenschøn, H. N., Byrne, E. M., Cichon, S., Clarke, T-K., Couvy-Duchesne, B., Craddock, N., de Geus, E. J. C., Degenhardt, F. & 77 othersDunn, E. C., Edwards, A. C., Fanous, A. H., Forstner, A. J., Frank, J., Gill, M., Gordon, S. D., Grabe, H. J., Hamilton, S. P., Hardiman, O., Hayward, C., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Hottenga, J-J., Ising, M., Jansen, R., Kloiber, S., Knowles, J. A., Lang, M., Li, Q. S., Lucae, S., MacIntyre, D. J., Madden, P. A. F., Martin, N. G., McGrath, P. J., McGuffin, P., McIntosh, A. M., Medland, S. E., Mehta, D., Middeldorp, C. M., Milaneschi, Y., Montgomery, G. W., Mors, O., Müller-Myhsok, B., Nauck, M., Nyholt, D. R., Nöthen, M. M., Owen, M. J., Penninx, B. W. J. H., Pergadia, M. L., Perlis, R. H., Peyrot, W. J., Porteous, D. J., Potash, J. B., Rice, J. P., Rietschel, M., Riley, B. P., Rivera, M., Schoevers, R., Schulze, T. G., Shi, J., Shyn, S. I., Smit, J. H., Smoller, J. W., Streit, F., Strohmaier, J., Teumer, A., Treutlein, J., Van der Auwera, S., van Grootheest, G., van Hemert, A. M., Völzke, H., Webb, B. T., Weissman, M. M., Wellmann, J., Willemsen, G., Witt, S. H., Levinson, D. F., Lewis, C. M., Wray, N. R., Flint, J., Sullivan, P. F. & Kendler, K. S., 28 Mar 2017, In : Translational psychiatry. 7, 3, p. e1074Research output: Contribution to journal › Article

An Examination of Polygenic Score Risk Prediction in Individuals with First Episode PsychosisVassos, E., Di Forti, M., Coleman, J., Iyegbe, C., Prata, D., Euesden, J., O'Reilly, P., Curtis, C., Kolliakou, A., Patel, H., Newhouse, S., Traylor, M., Ajnakina, O., Mondelli, V., Marques, T. R., Gardner-Sood, P., Aitchison, K. J., Powell, J., Atakan, Z., Greenwood, K. E. & 10 othersSmith, S., Ismail, K., Pariante, C., Gaughran, F., Dazzan, P., Markus, H. S., David, A. S., Lewis, C. M., Murray, R. M. & Breen, G., 15 Mar 2017, In : Biological psychiatry. 81, 6, p. 470-477 8 p.Research output: Contribution to journal › Article

A bidirectional relationship between depression and the autoimmune disorders – New perspectives from the National Child Development StudyEuesden, J., Danese, A., Lewis, C. M. & Maughan, B., 6 Mar 2017, In : PLOS One. p. NA 0173015.Research output: Contribution to journal › Article

Genetic variation at 16q24.2 is associated with small vessel strokeTraylor, M., Malik, R., Nalls, M. A., Cotlarciuc, I., Radmanesh, F., Thorleifsson, G., Hanscombe, K. B., Langefeld, C., Saleheen, D., Rost, N. S., Yet, I., Spector, T. D., Bell, J. T., Hannon, E., Mill, J., Chauhan, G., Debette, S., Bis, J. C., Longstreth, W. T., Ikram, M. A. & 47 othersLauner, L. J., Seshadri, S., Hamilton-Bruce, M. A., Jimenez-Conde, J., Cole, J. W., Schmidt, R., Słowik, A., Lemmens, R., Lindgren, A., Melander, O., Grewal, R. P., Sacco, R. L., Rundek, T., Rexrode, K., Arnett, D. K., Johnson, J. A., Benavente, O. R., Wasssertheil-Smoller, S., Lee, J. M., Pulit, S. L., Wong, Q., Rich, S. S., de Bakker, P. I. W., McArdle, P. F., Woo, D., Anderson, C. D., Xu, H., Heitsch, L., Fornage, M., Jern, C., Stefansson, K., Thorsteinsdottir, U., Gretarsdottir, S., Lewis, C. M., Sharma, P., Sudlow, C. L. M., Rothwell, P. M., Boncoraglio, G. B., Thijs, V., Levi, C., Meschia, J. F., Rosand, J., Kittner, S. J., Mitchell, B. D., Dichgans, M., Worrall, B. B. & Markus, H. S., 1 Mar 2017, In : Annals of Neurology. 81, 3, p. 383-394 12 p.Research output: Contribution to journal › Article

Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

Hinney, A., Kesselmeier, M., Jall, S., Volckmar, A. L., Föcker, M., Antel, J., Heid, I. M., Winkler, T. W., Grant, S. F. A., Guo, Y., Bergen, A. W., Kaye, W., Berrettini, W., Hakonarson, H., Herpertz-Dahlmann, B., De Zwaan, M., Herzog, W., Ehrlich, S., Zipfel, S., Egberts, K. M. & 529 othersAdan, R., Brandys, M., Van Elburg, A., Boraska Perica, V., Müller, T. D., Tschöp, M. H., Zeggini, E., Bulik, C. M., Collier, D., Scherag, A., Müller, T. D., Hebebrand, J., Perica, V. B., Franklin, C. S., Floyd, J. A. B., Thornton, L. M., Huckins, L. M., Southam, L., Rayner, N. W., Tachmazidou, I., Klump, K. L., Treasure, J., Lewis, C. M., Schmidt, U., Tozzi, F., Iezebrink, K., Hebebrand, J., Gorwood, P., Adan, R. A. H., Kas, M. J. H., Favaro, A., Santonastaso, P., Fernández-Aranda, F., Gratacos, M., Rybakowski, F., Dmitrzak-Weglarz, M., Kaprio, J., Keski-Rahkonen, A., Raevuori-Helkamaa, A., Van Furth, E. F., Slof-Op’t Landt, M. C. T., Hudson, J. I., Reichborn-Kjennerud, T., Knudsen, G. P. S., Monteleone, P., Kaplan, A. S., Karwautz, A., Hakonarson, H., Berrettini, W. H., Guo, Y., Li, D., Schork, N. J., Komaki, G., Ando, T., Inoko, H., Esko, T., Fischer, K., Männik, K., Metspalu, A., Baker, J. H., Cone, R. D., Dackor, J., DeSocio, J. E., Hilliard, C. E., O’Toole, J. K., Pantel, J., Szatkiewicz, J. P., Taico, C., Zerwas, S., Trace, S. E., Davis, O. S. P., Helder, S., Bühren, K., Burghardt, R., de Zwaan, M., Egberts, K., Ehrlich, S., Herpertz-Dahlmann, B., Herzog, W., Imgart, H., Scherag, A., Scherag, S., Zipfel, S., Boni, C., Ramoz, N., Versini, A., Brandys, M. K., Danner, U. N., de Kove, C., Hendriks, J., Koeleman, B. P. C., Ophoff, R. A., Strengman, E., van Elburg, A. A., Bruson, A., Clementi, M., Degortes, D., Forzan, M., Tenconi, E., Docampo, E., Jiménez-Murcia, G. E. S., Lissowska, J., Rajewski, A., Szeszenia-Dabrowska, N., Slopien, A., Hauser, J., Karhunen, L., Meulenbelt, I., Slagboom, P. E., Tortorella, A., Maj, M., Dedoussis, G., Dikeos, D., Gonidakis, F., Tziouvas, K., Tsitsika, A., Papezova, H., Slachtova, L., Martaskova, D., Kennedy, J. L., Levitan, R. D., Yilmaz, Z., Huemer, J., Koubek, D., Merl, E., Wagner, G., Lichtenstein, P., Breen, G., Cohen-Woods, S., Farmer, A., McGuffin, P., Cichon, S., Giegling, I., Herms, S., Rujescu, D., Schreiber, S., Wichmann, H. E., Christian, D., Sladek, R., Gambaro, G., Soranzo, N., Julia, A., Marsal, S., Rabionet, R., Gaborieau, V., Dick, D. M., Palotie, A., Ripatti, S., Widén, E., Andreassen, O. A., Espeseth, T., Lundervold, A., Reinvang, I., Steen, V. M., Le Hellard, S., Mattingsdal, M., Ntalla, I., Bencko, V., Foretova, L., Janout, V., Navratilova, M., Gallinger, S., Pinto, D., Scherer, S. W., Aschauer, H., Carlberg, L., Schosser, A., Alfredsson, L., Ding, B., Klareskog, L., Padyukov, L., Finan, C., Kalsi, G., Roberts, M., Logan, D. W., Peltonen, L., Ritchie, G. R. S., Barrett, J. C., Estivill, X., Hinney, A., Sullivan, P. F., Collier, D. A., Zeggini, E., Bulik, C. M., Anderson, C. A., Barrett, J. C., Floyd, J. A. B., Franklin, C. S., McGinnis, R., Soranzo, N., Zeggini, E., Sambrook, J., Stephens, J., Ouwehand, W. H., McArdle, W. L., Ring, S. M., Strachan, D. P., Alexander, G., Bulik, C. M., Collier, D. A., Conlon, P. J., Dominiczak, A., Duncanson, A., Hill, A., Langford, C., Lord, G., Maxwell, A. P., Morgan, L., Peltonen, L., Sandford, R. N., Sheerin, N., Vannberg, F. O., Blackburn, H., Chen, W. M., Edkins, S., Gillman, M., Gray, E., Hunt, S. E., Nengut, S. G., Potter, S., Rich, S. S., Simpkin, D., Whittaker, P., Adair, L. S., Ang, W., Atalay, M., van Beijsterveldt, T., Bergen, N., Benke, K., Berry, D. J., Boomsma, D. I., Bradfield, J. P., Charoen, P., Coin, L., Cooper, C., Cousminer, D. L., Das, S., Davis, O. S., Dedoussis, G. V., Elliott, P., Estivill, X., Evans, D. M., Feenstra, B., Flexeder, C., Frayling, T., Freathy, R. M., Gaillard, R., Geller, F., Gillman, M., Grant, S. 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J., Deloukas, P., Döring, A., Davey Smith, G., Easton, D. F., Eiriksdottir, G., Emilsson, V., Eriksson, J., Ferrucci, L., Folsom, A. R., Foroud, T., Garcia, M., Gasparini, P., Geller, F., Gieger, C., Gudnason, V., Hall, P., Hankinson, S. E., Ferreli, L., Heath, A. C., Hernandez, D. G., Hofman, A., Hu, F. B., Illig, T., Järvelin, M. R., Johnson, A. D., Karasik, D., Khaw, K. T., Kiel, D. P., Kilpeläinen, T. O., Kolcic, I., Kraft, P., Launer, L. J., Laven, J. S., Li, S., Liu, J., Levy, D., Martin, N. G., McArdle, W. L., Melbye, M., Mooser, V., Murray, J. C., Murray, S. S., Nalls, M. A., Navarro, P., Nelis, M., Ness, A. R., Northstone, K., Oostra, B. A., Peacock, M., Palmer, L. J., Palotie, A., Paré, G., Parker, A. N., Pedersen, N. L., Peltonen, L., Pennell, C. E., Pharoah, P., Polasek, O., Plump, A. S., Pouta, A., Porcu, E., Rafnar, T., Rice, J. P., Ring, S. M., Rivadeneira, F., Rudan, I., Sala, C., Salomaa, V., Sanna, S., Schlessinger, D., Schork, N. J., Scuteri, A., Segrè, A. V.,

Shuldiner, A. R., Soranzo, N., Sovio, U., Srinivasan, S. R., Strachan, D. P., Tammesoo, M. L., Tikkanen, E., Toniolo, D., Tsui, K., Tryggvadottir, L., Tyrer, J., Uda, M., van Dam, R. M., van Meurs, J. B., Vollenweider, P., Waeber, G., Wareham, N. J., Waterworth, D. M., Weedon, M. N., Wichmann, H. E., Willemsen, G., Wilson, J. F., Wright, A. F., Young, L., Zhai, G., Zhuang, W. V., Bierut, L. J., Boyd, H. A., Crisponi, L., Demerath, E. W., van Duijn, C. M., Econs, M. J., Harris, T. B., Hunter, D. J., Loos, R. J., Metspalu, A., Montgomery, G. W., Ridker, P. M., Spector, T. D., Streeten, E. A., Stefansson, K., Thorsteinsdottir, U., Uitterlinden, A. G., Widen, E., Murabito, J. M., Ong, K. K., Murray, A., Brandt, H., Crawford, S., Crow, S., Fichter, M. M., Halmi, K. A., Johnson, C., Kaplan, A. S., La Via, M., Mitchell, J., Strober, M., Rotondo, A., Treasure, J., Woodside, D. B., Bulik, C. M., Keel, P., Klump, K. L., Lilenfeld, L., Thornton, L. M., Plotnicov, K., Bergen, A. W., Berrettini, W., Kaye, W. & Magistretti, P., 1 Feb 2017, In : Molecular Psychiatry. 22, 2, p. 192-201 10 p.Research output: Contribution to journal › Article

Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive DisorderZeng, Y., Navarro, P., Shirali, M., Howard, D. M., Adams, M. J., Hall, L. S., Clarke, T. K., Thomson, P. A., Smith, B. H., Murray, A., Padmanabhan, S., Hayward, C., Boutin, T., MacIntyre, D. J., Lewis, C. M., Wray, N. R., Mehta, D., Penninx, B. W. J. H., Milaneschi, Y., Baune, B. T. & 19 othersAir, T., Hottenga, J. J., Mbarek, H., Castelao, E., Pistis, G., Schulze, T. G., Streit, F., Forstner, A. J., Byrne, E. M., Martin, N. G., Breen, G., Müller-Myhsok, B., Lucae, S., Kloiber, S., Domenici, E., Deary, I. J., Porteous, D. J., Haley, C. S. & McIntosh, A. M., 16 Dec 2016, In : Biological psychiatry. 10 p.Research output: Contribution to journal › Article

An Analysis of Two Genome-Wide Association Meta-Analyses Identifies a New Locus for Broad Depression PhenotypeDirek, N., Williams, S., Smith, J. A., Ripke, S., Air, T., Amare, A. T., Amin, N., Baune, B. T., Bennett, D. A., Blackwood, D. H. R., Boomsma, D., Breen, G., Buttenschøn, H. N., Byrne, E. M., Børglum, A. D., Castelao, E., Cichon, S., Clarke, T-K., Cornelis, M. C., Dannlowski, U. & 82 othersDe Jager, P. L., Demirkan, A., Domenici, E., van Duijn, C. M., Dunn, E. C., Eriksson, J. G., Esko, T., Faul, J. D., Ferrucci, L., Fornage, M., Geus, E. D., Gill, M., Gordon, S. D., Grabe, H. J., Grootheest, G. V., Hamilton, S. P., Hartman, C. A., Heath, A. C., Hek, K., Hofman, A., Homuth, G., Horn, C., Hottenga, J. J., Kardia, S. L. R., Kloiber, S., Koenen, K., Kutalik, Z., Ladwig, K-H., Lahti, J., Levinson, D. F., Lewis, C. M., Lewis, G., Li, Q. S., Llewellyn, D. J., Lucae, S., Lunetta, K. L., MacIntyre, D. J., Madden, P., Martin, N. G., McIntosh, A. M., Metspalu, A., Milaneschi, Y., Montgomery, G. W., Mors, O., Mosley Jr, T. H., Murabito, J. M., Müller-Myhsok, B., Nöthen, M. M., Nyholt, D. R., O’Donovan, M. C., Penninx, B. W., Pergadia, M. L., Perlis, R., Potash, J. B., Preisig, M., Purcell, S. M., Quiroz, J. A., Räikkönen, K., Rice, J. P., Rietschel, M., Rivera Sanchez, M., Schulze, T. G., Shi, J., Shyn, S., Sinnamon, G. C., Smit, J. H., Smoller, J. W., Snieder, H., Tanaka, T., Tansey, K. E., Teumer, A., Uher, R., Umbricht, D., der Auwera, S. V., Ware, E. B., Weir, D. R., Weissman, M. M., Willemsen, G., Yang, J., Zhao, W., Tiemeier, H. & Sullivan, P. F., 8 Dec 2016, In : Biological psychiatry.Research output: Contribution to journal › Article

Rare genetic variation in UNC13A may modify survival in amyotrophic lateral sclerosisGaastra, B., Shatunov, A., Pulit, S., Jones, A. R., Sproviero, W., Gillett, A., Chen, Z., Kirby, J., Fogh, I., Powell, J. F., Leigh, P. N., Morrison, K. E., Shaw, P. J., Shaw, C. E., van den Berg, L. H., Veldink, J. H., Lewis, C. M. & Al-Chalabi, A., 2 Sep 2016, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration . 17, 7-8, p. 593-599 7 p.Research output: Contribution to journal › Article

Meta-analysis of the Association Between the Level of Cannabis Use and Risk of PsychosisMarconi, A., Di Forti, M., Lewis, C. M., Murray, R. M. & Vassos, E., 1 Sep 2016, In : Schizophrenia Bulletin. 42, 5, p. 1262-1269 8 p.Research output: Contribution to journal › Article

Impact of intensive treatment and remission on health-related quality of life in early and established rheumatoid arthritisScott, I. C., Ibrahim, F., Lewis, C. M., Scott, D. L. & Strand, V., 26 Aug 2016, In : BMJ Open. 2, 2, 10 p., e000270.Research output: Contribution to journal › Article

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosisvan Rheenen, W., Shatunov, A., Dekker, A. M., McLaughlin, R. L., Diekstra, F. P., Pulit, S. L., van der Spek, R. A. A., Võsa, U., de Jong, S., Robinson, M. R., Yang, J., Fogh, I., van Doormaal, P. T., Tazelaar, G. H. P., Koppers, M., Blokhuis, A. M., Sproviero, W., Jones, A. R., Kenna, K. P., van Eijk, K. R. & 31 othersHarschnitz, O., Schellevis, R. D., Brands, W. J., Medic, J., Menelaou, A., Vajda, A., Ticozzi, N., Lin, K., Rogelj, B., Vrabec, K., Ravnik-Glavač, M., Koritnik, B., Zidar, J., Leonardis, L., Grošelj, L. D., Millecamps, S., Salachas, F., Meininger, V., de Carvalho, M., Pinto, S., Fratta, P., Topp, S., Curtis, C., Shaw, C. E., Smith, B. N., Leigh, P. N., Powell, J., Lewis, C. M., Breen, G., Al-Chalabi, A. & PARALS Registry, 25 Jul 2016, In : Nature Genetics.Research output: Contribution to journal › Article

Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral SclerosisFogh, I., Lin, K., Tiloca, C., Rooney, J., Gellera, C., Diekstra, F. P., Ratti, A., Shatunov, A., Van Es, M. A., Proitsi, P., Jones, A., Sproviero, W., Chiò, A., McLaughlin, R. L., Sorarù, G., Corrado, L., Stahl, D., Del Bo, R., Cereda, C., Castellotti, B. & 29 othersGlass, J. D., Newhouse, S., Dobson, R., Smith, B. N., Topp, S., Van Rheenen, W., Meininger, V., Melki, J., Morrison, K. E., Shaw, P. J., Leigh, P. N., Andersen, P. M., Comi, G. P., Ticozzi, N., Mazzini, L., D'Alfonso, S., Traynor, B. J., Van Damme, P., Robberecht, W., Brown, R. H., Landers, J. E., Hardiman, O., Lewis, C. M., Van Den Berg, L. H., Shaw, C. E., Veldink, J. H., Silani, V., Al-Chalabi, A. & Powell, J., 1 Jul 2016, In : JAMA Neurology. 73, 7, p. 812-820 9 p.Research output: Contribution to journal › Article

Combining clinical variables to optimize prediction of antidepressant treatment outcomesIniesta, R., Malki, K., Maier, W., Rietschel, M., Mors, O., Hauser, J., Henigsberg, N., Dernovsek, M. Z., Souery, D., Stahl, D., Dobson, R., Aitchison, K. J., Farmer, A., Lewis, C. M., McGuffin, P. & Uher, R., Jul 2016, In : Journal of psychiatric research. 78, p. 94-102 9 p.Research output: Contribution to journal › Article

Using clinical characteristics to identify which patients with major depressive disorder have a higher genetic load for three psychiatric disordersVerduijn, J., Milaneschi, Y., Peyrot, W. J., Jan Hottenga, J., Abdellaoui, A., de Geus, E. J. C., Smit, J. H., Breen, G., Lewis, C. M., Boomsma, D. I., Beekman, A. T. F. & Penninx, B. W. J. H., 10 Jun 2016, In : Biological psychiatry.Research output: Contribution to journal › Article

Genome-wide Association for Major Depression Through Age at Onset StratificationPsychiatric Genomics Consortium MDD Working Group, 24 May 2016, In : Biological psychiatry.Research output: Contribution to journal › Article

Genetic discovery in multi-ethnic populationsTraylor, M. & Lewis, C. M., 4 May 2016, European journal of human genetics : EJHG, 24, p. 1097-1098 2 p.Research output: Contribution to specialist publication › Letter

Shared genetic contribution to ischemic stroke and Alzheimer's disease: Ischemic Stroke and Alzheimer's DiseaseTraylor, M., Adib-samii, P., Harold, D., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., METASTROKE and International Genomics of Alzheimer's Project (IGAP) investigators, Lovestone, S. H. & Proitsi, P., 1 May 2016, In : Annals of Neurology. 79, 5, p. 739-747Research output: Contribution to journal › Article

A genome-wide test of the differential susceptibility hypothesis reveals a genetic predictor of differential response to psychological treatments for child anxiety disordersKeers, R., Coleman, J., Lester, K. J., Roberts, S. L., Breen, G. D., Thastum, M., Bögels, S., Schneider, S., Heiervang, E., Meiser-Stedman, R., Nauta, M., Creswell, C., Thirlwall, K., Rapee, R. M., Hudson, J. L., Lewis, C. M., Plomin, R. J. & Eley, T. C., 5 Apr 2016, In : Psychotherapy and Psychosomatics. 85, p. 146-158Research output: Contribution to journal › Article

RHEUMATOID ARTHRITIS RISK AND PROGNOSTIC FACTORS IDENTIFIED IN EUROPEAN AND ASIAN POPULATIONS ARE ALSO RELEVANT IN AFRICAN ANCESTRY INDIVIDUALS: THE GENRA STUDYTraylor, M., Curtis, C., Patel, H., Breen, G., Lee, S. H., Xu, X., Newhouse, S., Dobson, R., Steer, S., Cope, A., Markus, H. S., Lewis, C. & Scott, I. C., Apr 2016, In : Rheumatology. 55, p. 89-89Research output: Contribution to journal › Article

Polygenic interactions with environmental adversity in the aetiology of major depressive disorderMullins, N., Power, R. A., Fisher, H., Hanscombe, K. B., Euesden, J., Iniesta, R., Levinson, D. F., Weissman, M. M., Potash, J. B., Shi, J., Uher, R., Cohen-Woods, S., Rivera, M., Jones, L., Jones, I., Craddock, N., Owen, M. J., Korszun, A., Craig, I. W., Farmer, A. E. & 3 othersMcGuffin, P., Breen, G. & Lewis, C. M., Mar 2016, In : Psychological Medicine. 46, 4, p. 759-770 12 p.Research output: Contribution to journal › Article

Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with strokeTraylor, M., Zhang, C. R., Adib-Samii, P., Devan, W. J., Parsons, O. E., Lanfranconi, S., Gregory, S., Cloonan, L., Falcone, G. J., Radmanesh, F., Fitzpatrick, K., Kanakis, A., Barrick, T. R., Moynihan, B., Lewis, C. M., Boncoraglio, G. B., Lemmens, R., Thijs, V., Sudlow, C., Wardlaw, J. & 10 othersRothwell, P. M., Meschia, J. F., Worrall, B. B., Levi, C., Bevan, S., Furie, K. L., Dichgans, M., Rosand, J., Markus, H. S. & Rost, N., 12 Jan 2016, In : Neurology. 86, 2, p. 146-153 8 p.Research output: Contribution to journal › Article

Differences in Common Genetic Predisposition to Ischemic Stroke by Age and SexTraylor, M., Rutten-Jacobs, L. C. A., Holliday, E. G., Malik, R., Sudlow, C., Rothwell, P. M., Maguire, J. M., Koblar, S. A., Bevan, S., Boncoraglio, G., Dichgans, M., Levi, C., Lewis, C. M. & Markus, H. S., 1 Nov 2015, In : Stroke. 46, 11, p. 3042-3047 6 p.Research output: Contribution to journal › Article

Establishing the characteristics of an effective pharmacogenetic test for clozapine-induced agranulocytosisVerbelen, M., Collier, D. A., Cohen, D., MacCabe, J. H. & Lewis, C. M., 24 Oct 2015, In : The pharmacogenomics journal. 15, 5, p. 461-466 6 p.Research output: Contribution to journal › Article

Genetic Architecture of Lacunar StrokeTraylor, M., Bevan, S., Baron, J. C., Hassan, A., Lewis, C. M. & Markus, H. S., 28 Sep 2015, In : Stroke. 46, 9, p. 2407-2412 6 p.Research output: Contribution to journal › Article

Genetic Factors Influencing Coagulation Factor XIII B-Subunit Contribute to Risk of Ischemic StrokeHanscombe, K. B., Traylor, M., Hysi, P. G., Bevan, S., Dichgans, M., Rothwell, P. M., Worrall, B. B., Seshadri, S., Sudlow, C., Williams, F. M. K., Markus, H. S., Lewis, C. M. & METASTROKE Consortium, Aug 2015, In : Stroke. 46, 8, p. 2069-74 6 p.Research output: Contribution to journal › Article

The similarity of the structure of DSM-IV criteria for major depression in depressed women from China, the United States and EuropeKendler, K. S., Aggen, S. H., Li, Y., Lewis, C. M., Breen, G., Boomsma, D. I., Bot, M., Penninx, B. W. J. H. & Flint, J., 1 Jul 2015, In : Psychological Medicine. 45, 9, p. 1945-1954 10 p.Research output: Contribution to journal › Article

How close are we to a pharmacogenomic test for clozapine-induced agranulocytosis?Verbelen, M. & Lewis, C. M., 1 Jun 2015, In : PHARMACOGENOMICS. 16, 9, p. 915-917 3 p.Research output: Contribution to journal › Article

Do Genetic Susceptibility Variants Associate With Disease Severity In Early Active Rheumatoid Arthritis?Scott, I. C., Rijsdijk, F., Walker, J., Quist, J. S., Spain, S. L., Tan, R., Steer, S., Okada, Y., Raychaudhuri, S., Cope, A. P. & Lewis, C. M., 15 May 2015, In : Journal of Rheumatology. 42, 7, p. 1131-1140 10 p.Research output: Contribution to journal › Article

A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorderHung, C-F., Breen, G., Czamara, D., Corre, T., Wolf, C., Kloiber, S., Bergmann, S., Craddock, N., Gill, M., Holsboer, F., Jones, L., Jones, I., Korszun, A., Kutalik, Z., Lucae, S., Maier, W., Mors, O., Owen, M. J., Rice, J., Rietschel, M. & 10 othersUher, R., Vollenweider, P., Waeber, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Müller-Myhsok, B., Preisig, M., McGuffin, P. & Rivera, M., 17 Apr 2015, In : BMC Medicine. 13, 10 p., 86.Research output: Contribution to journal › Article

Pooled Sequencing of 531 Genes in Inflammatory Bowel Disease Identifies an Associated Rare Variant in BTNL2 and Implicates Other Immune Related GenesPrescott, N. J., Lehne, B., Stone, K., Lee, J. C., Taylor, K., Knight, J., Papouli, E., Mirza, M. M., Simpson, M. A., Spain, S. L., Lu, G., Fraternali, F., Bumpstead, S. J., Gray, E., Amar, A., Bye, H., Green, P., Chung-Faye, G., Hayee, BH., Pollok, R. & 10 othersSatsangi, J., Parkes, M., Barrett, J. C., Mansfield, J. C., Sanderson, J., Lewis, C. M., Weale, M. E., Schlitt, T., Mathew, C. G. & UK IBD Genetics Consortium, 11 Feb 2015, In : PL o S Genetics. 11, 2, 19 p., e1004955.Research output: Contribution to journal › Article

Familiality and SNP heritability of age at onset and episodicity in major depressive disorderFerentinos, P., Koukounari, A., Power, R., Rivera, M., Uher, R., Craddock, N., Owen, M. J., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Ising, M., Maier, W., Mors, O., Rietschel, M., Preisig, M., Binder, E. B., Aitchison, K. J., Mendlewicz, J. & 9 othersSouery, D., Hauser, J., Henigsberg, N., Breen, G., Craig, I. W., Farmer, A. E., Müller-Myhsok, B., McGuffin, P. & Lewis, C. M., 2015, In : Psychological Medicine. 11 p.Research output: Contribution to journal › Article

The relationship between schizophrenia and rheumatoid arthritis revisited: Genetic and epidemiological analysesEuesden, J., Breen, G., Farmer, A., McGuffin, P. & Lewis, C. M., 2015, In : American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 8 p.Research output: Contribution to journal › Article

Pharmacogenetics of pemetrexed combination therapy in lung cancer: pathway analysis reveals novel toxicity associationsCorrigan, A., Walker, J. L., Wickramasinghe, S., Hernandez, M. A., Newhouse, S. J., Folarin, A. A., Lewis, C. M., Sanderson, J. D., Spicer, J. & Marinaki, A. M., Oct 2014, In : Pharmacogenomics journal. 14, 5, p. 411-417 7 p.Research output: Contribution to journal › Article

A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed ApproachTraylor, M., Mäkelä, K-M., Kilarski, L. L., Holliday, E. G., Devan, W. J., Nalls, M. A., Wiggins, K. L., Zhao, W., Cheng, Y-C., Achterberg, S., Malik, R., Sudlow, C., Bevan, S., Raitoharju, E., Oksala, N., Thijs, V., Lemmens, R., Lindgren, A., Slowik, A., Maguire, J. M. & 19 othersWalters, M., Algra, A., Sharma, P., Attia, J. R., Boncoraglio, G. B., Rothwell, P. M., de Bakker, P. I. W., Bis, J. C., Saleheen, D., Kittner, S. J., Mitchell, B. D., Rosand, J., Meschia, J. F., Levi, C., Dichgans, M., Lehtimäki, T., Lewis, C. M., Markus, H. S. & METASTROKE, International Stroke Genetics Consortium, Wellcome Trust Case Consortium 2 (WTCCC2), 31 Jul 2014, In : PL o S Genetics. 10, 7, 11 p., e1004469.Research output: Contribution to journal › Article

The correlation between reading and mathematics ability at age twelve has a substantial genetic componentDavis, O. S. P., Band, G., Pirinen, M., Haworth, C. M. A., Meaburn, E. L., Kovas, Y., Harlaar, N., Docherty, S. J., Hanscombe, K. B., Trzaskowski, M., Curtis, C. J. C., Strange, A., Freeman, C., Bellenguez, C., Su, Z., Pearson, R., Vukcevic, D., Langford, C., Deloukas, P., Hunt, S. & 31 othersGray, E., Dronov, S., Potter, S. C., Tashakkori-Ghanbaria, A., Edkins, S., Bumpstead, S. J., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Duncanson, A., Jankowski, J. A. Z., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Rautanen, A., Sawcer, S. J., Trembath, R. C., Viswanathan, A. C., Wood, N. W., Barroso, I., Peltonen, L., Dale, P. S., Petrill, S. A., Schalkwyk, L. S., Craig, I. W., Lewis, C. M., Price, T. S., Plomin, R. & Wellcome Trust Case Control Consortium, 8 Jul 2014, In : Nature Communications. 5, 6 p., 4204.Research output: Contribution to journal › Article

Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: A genome-wide association and polygenic scoring studyMullins, N., Perroud, N., Uher, R., Butler, A. W., Cohen-Woods, S., Rivera, M., Malki, K., Euesden, J., Power, R. A., Tansey, K. E., Jones, L., Jones, I., Craddock, N., Owen, M. J., Korszun, A., Gill, M., Mors, O., Preisig, M., Maier, W., Rietschel, M. & 10 othersRice, J. P., Müller-Myhsok, B., Binder, E. B., Lucae, S., Ising, M., Craig, I. W., Farmer, A. E., McGuffin, P., Breen, G. & Lewis, C. M., Jul 2014, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 165, 5, p. 428-437 10 p.Research output: Contribution to journal › Article

Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation studyHung, C-F., Rivera, M., Craddock, N., Owen, M. J., Gill, M., Korszun, A., Maier, W., Mors, O., Preisig, M., Rice, J. P., Rietschel, M., Jones, L., Middleton, L., Aitchison, K. J., Davis, O. S. P., Breen, G., Lewis, C., Farmer, A. & McGuffin, P., Jul 2014, In : British Journal of Psychiatry. 205, 1, p. 24-28 5 p.Research output: Contribution to journal › Article

A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosisFogh, I., Ratti, A., Gellera, C., Lin, K., Tiloca, C., Moskvina, V., Corrado, L., Sorarù, G., Cereda, C., Corti, S., Gentilini, D., Calini, D., Castellotti, B., Mazzini, L., Querin, G., Gagliardi, S., Del Bo, R., Conforti, F. L., Siciliano, G., Inghilleri, M. & 31 othersSaccà, F., Bongioanni, P., Penco, S., Corbo, M., Sorbi, S., Filosto, M., Ferlini, A., Di Blasio, A. M., Signorini, S., Shatunov, A., Jones, A., Shaw, P. J., Morrison, K. E., Farmer, A. E., Van Damme, P., Robberecht, W., Chiò, A., Traynor, B. J., Sendtner, M., Melki, J., Meininger, V., Hardiman, O., Andersen, P. M., Leigh, N. P., Glass, J. D., Shaw, C. E., Weale, M. E., Lewis, C. M., Al-Chalabi, A., Powell, J. & the SLAGEN Consortium Collaborators, 15 Apr 2014, In : Human Molecular Genetics. 23, 8, p. 2220-2231 12 p., N/A.Research output: Contribution to journal › Article

Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibilityLi, M., Luo, X., Rietschel, M., Lewis, C. M., Mattheisen, M., Mueller-Myhsok, B., Jamain, S., Leboyer, M., Landen, M., Thompson, P. M., Cichon, S., Noethen, M. M., Schulze, T. G., Sullivan, P. F., Bergen, S. E., Donohoe, G., Morris, D. W., Hargreaves, A., Gill, M., Corvin, A. & 33 othersHultman, C., Toga, A. W., Shi, L., Lin, Q., Shi, H., Gan, L., Meyer-Lindenberg, A., Czamara, D., Henry, C., Etain, B., Bis, J. C., Ikram, M. A., Fornage, M., Debette, S., Launer, L. J., Seshadri, S., Erk, S., Walter, H., Heinz, A., Bellivier, F., Stein, J. L., Medland, S. E., Vasquez, A. A., Hibar, D. P., Franke, B., Martin, N. G., Wright, M. J., Su, B., MooDS Bipolar Consortium, Swedish Bipolar Study Group, Alzheimer's Dis Neuroimaging, ENIGMA Consortium & CHARGE Consortium, Apr 2014, In : Molecular Psychiatry. 19, 4, p. 452-461 10 p.Research output: Contribution to journal › Article

A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigationBramon, E., Pirinen, M., Strange, A., Lin, K., Freeman, C., Bellenguez, C., Su, Z., Band, G., Pearson, R., Vukcevic, D., Langford, C., Deloukas, P., Hunt, S., Gray, E., Dronov, S., Potter, S. C., Tashakkori-Ghanbaria, A., Edkins, S., Bumpstead, S. J., Arranz, M. J. & 31 othersBakker, S., Bender, S., Bruggeman, R., Cahn, W., Chandler, D., Collier, D. A., Crespo-Facorro, B., Dazzan, P., de Haan, L., Di Forti, M., Dragović, M., Giegling, I., Hall, J., Iyegbe, C., Jablensky, A., Kravariti, E., Mata, I., McDonald, C., Pariante, C. M., Picchioni, M., Shaikh, M., Toulopoulou, T., Van Os, J., Walshe, M., Mathew, C. G., Plomin, R., Trembath, R. C., Lewis, C. M., Murray, R. M., Powell, J. & Psychosis Endophenotypes International Consortium, 1 Mar 2014, In : Biological psychiatry. 75, 5, p. 386-397 12 p.Research output: Contribution to journal › Article

Investigating the genetic variation underlying episodicity in major depressive disorder: Suggestive evidence for a bipolar contributionFerentinos, P., Rivera, M., Ising, M., Spain, S. L., Cohen-Woods, S., Butler, A. W., Craddock, N., Owen, M. J., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Maier, W., Mors, O., Rietschel, M., Lucae, S., Binder, E. B., Preisig, M., Tozzi, F. & 7 othersMuglia, P., Breen, G., Craig, I. W., Farmer, A. E., Müller-Myhsok, B., McGuffin, P. & Lewis, C. M., Feb 2014, In : Journal of Affective Disorders. 155, N/A, p. 81-89 9 p., N/A.Research output: Contribution to journal › Article

ACPA-positive and ACPA-negative rheumatoid arthritis differ in their requirements for combination DMARDs and corticosteroids: secondary analysis of a randomized controlled trialSeegobin, S. D., Ma, M. H., Dahanayake, C., Cope, A. P., Scott, D. L., Lewis, C. M. & Scott, I. C., 16 Jan 2014, In : Arthritis Research and Therapy. 16, 1, p. N/A 12 p., R13.Research output: Contribution to journal › Article

Genetic susceptibility for bipolar disorder and response to antidepressants in major depressive disorderTansey, K. E., Guipponi, M., Domenici, E., Lewis, G., Malafosse, A., O'Donovan, M., Wendland, J. R., Lewis, C. M., McGuffin, P. & Uher, R., Jan 2014, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 165, 1, p. 77-83 7 p., N/A.Research output: Contribution to journal › Article

A genome-wide association study of anorexia nervosaBoraska, V., Franklin, C. S., Floyd, J. A. B., Thornton, L. M., Huckins, L. M., Southam, L., Rayner, N. W., Tachmazidou, I., Klump, K. L., Treasure, J., Lewis, C. M., Schmidt, U., Tozzi, F., Kiezebrink, K., Hebebrand, J., Gorwood, P., Adan, R. A. H., Kas, M. J. H., Favaro, A., Santonastaso, P. & 31 othersFernández-Aranda, F., Gratacos, M., Rybakowski, F., Dmitrzak-Weglarz, M., Kaprio, J., Keski-Rahkonen, A., Raevuori, A., Van Furth, E. F., Slof-Op 't Landt, M. C. T., Hudson, J. I., Reichborn-Kjennerud, T., Knudsen, G. P. S., Monteleone, P., Kaplan, A. S., Karwautz, A., Hakonarson, H., Berrettini, W. H., Guo, Y., Li, D., Schork, N. J., Davis, O. S. P., Helder, S., Breen, G., Cohen-Woods, S., Farmer, A., McGuffin, P., Kalsi, G., Roberts, M., Collier, D. A., The Wellcome Trust Case Control Consortium 3 & Lord, G., 2014, In : Molecular Psychiatry. N/A, N/A, p. N/A N/A.Research output: Contribution to journal › Article

A genome-wide association study of suicide severity scores in bipolar disorderZai, C. C., Gonçalves, V. F., Tiwari, A. K., Gagliano, S. A., Hosang, G., de Luca, V., Shaikh, S. A., King, N., Chen, Q., Xu, W., Strauss, J., Breen, G., Lewis, C. M., Farmer, A. E., McGuffin, P., Knight, J., Vincent, J. B. & Kennedy, J. L., 2014, In : Journal of psychiatric research. 7 p.Research output: Contribution to journal › Article

Comorbid medical illness in bipolar disorderForty, L., Ulanova, A., Jones, L., Jones, I., Gordon-Smith, K., Fraser, C., Farmer, A., McGuffin, P., Lewis, C. M., Hosang, G. M., Rivera, M. & Craddock, N., 2014, In : The British journal of psychiatry : the journal of mental science. 8 p.Research output: Contribution to journal › Article

Homogeneous case subgroups increase power in genetic association studiesTraylor, M., Markus, H. & Lewis, C. M., 2014, In : European journal of human genetics : EJHG. 7 p.Research output: Contribution to journal › Article

Investigation of blood mRNA biomarkers for suicidality in an independent sampleMullins, N., Hodgson, K., Tansey, K. E., Perroud, N., Maier, W., Mors, O., Rietschel, M., Hauser, J., Henigsberg, N., Souery, D., Aitchison, K., Farmer, A., McGuffin, P., Breen, G., Uher, R. & Lewis, C. M., 2014, In : Translational psychiatry. 4, 4 p., e474.Research output: Contribution to journal › Article

PRSice: Polygenic Risk Score softwareEuesden, J., Lewis, C. M. & O'Reilly, P. F., 2014, In : Bioinformatics (Oxford, England). 2 p.Research output: Contribution to journal › Article

Genome-wide association study of co-occurring anxiety in major depressionSchosser, A., Butler, A. W., Uher, R., Ng, M. Y., Cohen-Woods, S., Craddock, N., Owen, M. J., Korszun, A., Gill, M., Rice, J., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Preisig, M., Craig, I. W., Farmer, A. E. & 2 othersLewis, C. M. & McGuffin, P., Dec 2013, In : The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 14, 8, p. 611-621 11 p., N/A.Research output: Contribution to journal › Article

Genome-wide association analysis identifies 13 new risk loci for schizophreniaRipke, S., O'dushlaine, C., Chambert, K., Moran, J. L., K??hler, A. K., Akterin, S., Bergen, S. E., Collins, A. L., Crowley, J. J., Fromer, M., Kim, Y., Lee, S. H., Magnusson, P. K. E., Sanchez, N., Stahl, E. A., Williams, S., Wray, N. R., Xia, K., Bettella, F., Borglum, A. D. & 15 othersBulik-sullivan, B. K., Cormican, P., Craddock, N., De Leeuw, C., Durmishi, N., Gill, M., Lin, K., Neale, B. M., Powell, J., Riley, B. P., Walters, J. T., Multicenter Genetic Studies of Schizophrenia Consortium, Psychosis Endophenotypes International Consortium, Wellcome Trust Case Consortium 2 & Purcell, S., Oct 2013, In : Nature Genetics. 45, 10, p. 1150-1159 10 p.Research output: Contribution to journal › Article

Predicting outcomes following cognitive behaviour therapy in child anxiety disorders: the influence of genetic, demographic and clinical informationHudson, J. L., Lester, K. J., Lewis, C. M., Tropeano, M., Creswell, C., Collier, D. A., Cooper, P., Lyneham, H. J., Morris, T., Rapee, R. M., Roberts, S., Donald, J. A. & Eley, T. C., Oct 2013, In : Journal of Child Psychology and Psychiatry. 54, 10, p. 1086-1094 9 p.Research output: Contribution to journal › Article

Predicting the Risk of Rheumatoid Arthritis and Its Age of Onset through Modelling Genetic Risk Variants with SmokingScott, I. C., Seegobin, S. D., Steer, S., Tan, R., Forabosco, P., Hinks, A., Eyre, S., Morgan, A. W., Wilson, A. G., Hocking, L. J., Wordsworth, P., Barton, A., Worthington, J., Cope, A. P. & Lewis, C. M., 19 Sep 2013, In : PL o S Genetics. 9, 9, e1003808.Research output: Contribution to journal › Article

A genome-wide association study of a sustained pattern of antidepressant responseHunter, A. M., Leuchter, A. F., Power, R. A., Muthen, B., McGrath, P. J., Lewis, C. M., Cook, I. A., Garriock, H. A., McGuffin, P., Uher, R. & Hamilton, S. P., Sep 2013, In : Journal of Psychiatric Research. 47, 9, p. 1157-1165 9 p.Research output: Contribution to journal › Article

Estimating the heritability of reporting stressful life events captured by common genetic variantsPower, R. A., Wingenbach, T., Cohen-Woods, S., Uher, R., Ng, M. Y., Butler, A. W., Ising, M., Craddock, N., Owen, M. J., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Maier, W., Zobel, A., Mors, O., Placentino, A., Rietschel, M., Lucae, S. & 14 othersHolsboer, F., Binder, E. B., Keers, R., Tozzi, F., Muglia, P., Breen, G., Craig, I. W., Mueller-Myhsok, B., Kennedy, J. L., Strauss, J., Vincent, J. B., Lewis, C. M., Farmer, A. E. & McGuffin, P., Sep 2013, In : Psychological Medicine. 43, 9, p. 1965-1971 7 p.Research output: Contribution to journal › Article

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPsLee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Anney, R., Anttila, V., Arking, D. E., Asherson, P. & 31 othersAzevedo, M. H., Backlund, L., Badner, J. A., Bailey, A. J., Banaschewski, T., Barchas, J. D., Barnes, M. R., Barrett, T. B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen, S. E., Berrettini, W., Breen, G., Collier, D. A., Craig, D. W., Craig, I. W., Day, R., Farmer, A. E., Fombonne, E., Freitag, C. M., Kuntsi, J., Lewis, C. M., Lowe, J. K., McGuffin, P., Parr, J. R., Sonuga-Barke, E. J. S., Young, A. H. & Cross-Disorder Group of the Psychiatric Genomics Consortium, Sep 2013, In : Nature Genetics. 45, 9, p. 984-994 11 p., N/A.Research output: Contribution to journal › Article

Genome-wide association analysis accounting for environmental factors through propensity-score matching: Application to stressful live events in major depressive disorderPower, R. A., Cohen-Woods, S., Ng, M. Y., Butler, A. W., Craddock, N., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Maier, W., Zobel, A., Mors, O., Placentino, A., Rietschel, M., Aitchison, K. J., Tozzi, F., Muglia, P., Breen, G., Farmer, A. E. & 3 othersMcGuffin, P., Lewis, C. M. & Uher, R., Sep 2013, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 162, 6, p. 521-529 9 p., N/A.Research output: Contribution to journal › Article

Residual association at C9orf72 suggests an alternative amyotrophic lateral sclerosis-causing hexanucleotide repeatJones, A. R., Woollacott, I., Shatunov, A., Cooper-Knock, J., Buchman, V., Sproviero, W., Smith, B., Scott, K. M., Balendra, R., Abel, O., McGuffin, P., Ellis, C. M., Shaw, P. J., Morrison, K. E., Farmer, A., Lewis, C. M., Leigh, P. N., Shaw, C. E., Powell, J. F. & Al-Chalabi, A., Sep 2013, In : Neurobiology of Aging. 34, 9, p. 2234.e1-2234.e7 7 p., N/A.Research output: Contribution to journal › Article

Tumor necrosis factor and its targets in the inflammatory cytokine pathway are identified as putative transcriptomic biomarkers for escitalopram responsePowell, T., Schalkwyk, L. C., Heffernan, A. L., Breen, G., Lawrence, T., Price, T., Farmer, A. E., Aitchison, K. J., Craig, I. W., Danese, A., Lewis, C., McGuffin, P., Uher, R., Tansey, K. E. & D'Souza, U. M., Sep 2013, In : European Neuropsychopharmacology. 23, 9, p. 1105-1114 10 p.Research output: Contribution to journal › Article

Predicting treatment response in psoriasis using serum levels of adalimumab and etanercept: a single-centre, cohort studyMahil, S. K., Arkir, Z., Richards, G., Lewis, C. M., Barker, J. N. & Smith, C. H., Aug 2013, In : British Journal of Dermatology. 169, 2, p. 306-313 8 p., N/A.Research output: Contribution to journal › Article

Using Phenotypic Heterogeneity to Increase the Power of Genome-Wide Association Studies: Application to Age at Onset of Ischaemic Stroke SubphenotypesTraylor, M., Bevan, S., Rothwell, P. M., Sudlow, C., Dichgans, M., Markus, H. S. & Lewis, C. M., Jul 2013, In : Genetic Epidemiology. 37, 5, p. 495-503 9 p.Research output: Contribution to journal › Article

Pharmacogenetic variants in the DPYD, TYMS, CDA and MTHFR genes are clinically significant predictors of fluoropyrimidine toxicityLoganayagam, A., Hernandez, M. A., Corrigan, A., Fairbanks, L., Lewis, C. M., Harper, P., Maisey, N., Ross, P., Sanderson, J. & Marinaki, A. M., 25 Jun 2013, In : BJC: British Journal of Cancer. 108, 12, p. 2505-2515 11 p.Research output: Contribution to journal › Article

Incorporating non-genetic risk factors and behavioural modifications into risk prediction models for colorectal cancerYarnall, J. M., Crouch, D. J. M. & Lewis, C. M., Jun 2013, In : Cancer Epidemiology. 37, 3, p. 324-329 6 p.Research output: Contribution to journal › Article

The protective effect of alcohol on developing rheumatoid arthritis: a systematic review and meta-analysisScott, I. C., Tan, R., Stahl, D., Steer, S., Lewis, C. M. & Cope, A. P., May 2013, In : Rheumatology. 52, 5, p. 856-867 12 p.Research output: Contribution to journal › Literature review

Contribution of Common Genetic Variants to Antidepressant ResponseTansey, K. E., Guipponi, M., Hu, X., Domenici, E., Lewis, G., Malafosse, A., Wendland, J. R., Lewis, C. M., McGuffin, P. & Uher, R., 1 Apr 2013, In : Biological psychiatry. 73, 7, p. 679-682 4 p., N/A.Research output: Contribution to journal › Article

Common genetic variation and antidepressant efficacy in major depressive disorder: A meta-analysis of three genome-wide pharmacogenetic studiesUher, R., Tansey, K. E., Rietschel, M., Henigsberg, N., Maier, W., Mors, O., Hauser, J., Placentino, A., Souery, D., Farmer, A., Aitchison, K. J., Craig, I., McGuffin, P., Lewis, C. M., Ising, M., Lucae, S., Binder, E. B., Kloiber, S., Holsboer, F., Müller-Myhsok, B. & 8 othersRipke, S., Hamilton, S. P., Soundy, J., Laje, G., McMahon, F. J., Fava, M., Rush, A. J. & Perlis, R. H., 1 Feb 2013, In : The American Journal of Psychiatry. 170, 2, p. 207-217 11 p.Research output: Contribution to journal › Article

Genome-wide association analysis of copy number variation in recurrent depressive disorderRucker, J., Breen, G., Pinto, D., Pedroso, I., Lewis, C. M., Cohen-Woods, S., Uher, R., Schosser, A., Rivera, M., Aitchison, K. J., Craddock, N., Owen, M. J., Jones, L., Jones, I., Korszun, A., Muglia, P., Barnes, M. R., Preisig, M., Mors, O., Gill, M. & 8 othersMaier, W., Rice, J., Rietschel, M., Holsboer, F., Farmer, A. E., Craig, I. W., Scherer, S. W. & McGuffin, P., Feb 2013, In : Molecular Psychiatry. 18, 2, p. 183-189 7 p., N/A.Research output: Contribution to journal › Article

Fecundity of Patients With Schizophrenia, Autism, Bipolar Disorder, Depression, Anorexia Nervosa, or Substance Abuse vs Their Unaffected SiblingsPower, R., Kyaga, S., Uher, R., MacCabe, J., Långström, N., Landen, M., McGuffin, P., Lewis, C. M., Lichtenstein, P. & Svensson, A. C., Jan 2013, In : JAMA Psychiatry. 70, 1, p. 22-30 9 p.Research output: Contribution to journal › Article

Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disordersLigthart, L., Hottenga, J-J., Lewis, C. M., Farmer, A. E., Craig, I. W., Breen, G., Willemsen, G., Vink, J. M., Middeldorp, C. M., Byrne, E. M., Heath, A. C., Madden, P. A. F., Pergadia, M. L., Montgomery, G. W., Martin, N. G., Penninx, B. W. J. H., McGuffin, P., Boomsma, D. I. & Nyholt, D. R., 2013, In : Human Genetics.Research output: Contribution to journal › Article

REGENT: a risk assessment and classification algorithm for genetic and environmental factorsCrouch, D. J., Goddard, G. H. & Lewis, C. M., 2013, In : European journal of human genetics : EJHG. 21, 1, p. 109-11 3 p.Research output: Contribution to journal › Article

Distinct genetic association at the PLCE1 locus with oesophageal squamous cell carcinoma in the South African populationBye, H., Prescott, N. J., Lewis, C. M., Matejcic, M., Moodley, L., Robertson, B., van Rensburg, C., Parker, M. I. & Mathew, C. G., Nov 2012, In : Carcinogenesis. 33, 11, p. 2155-2161 7 p.Research output: Contribution to journal › Article

Meta-Analysis of the Association of Urbanicity With SchizophreniaVassos, E., Pedersen, C. B., Murray, R. M., Collier, D. A. & Lewis, C. M., Nov 2012, In : Schizophrenia Bulletin. 38, 6, p. 1118-1123 6 p., N/A.Research output: Contribution to journal › Article

Association of the IL-10 gene family locus on chromosome 1 with juvenile idiopathic arthritis (JIA)Omoyinmi, E., Forabosco, P., Hamaoui, R., Bryant, A., Hinks, A., Ursu, S., Wedderburn, L. R., Thomson, W., Lewis, C. M., Woo, P. & Childhood Arthritis Prospective Study (CAPS), 18 Oct 2012, In : PL o S One . 7, 10, p. e47673Research output: Contribution to journal › Article

Dissecting the genetic heterogeneity of depression through age at onsetPower, R., Keers, R., Ng, M. Y., Butler, A. W., Uher, R., Cohen-Woods, S., Ising, M., Craddock, N., Owen, M. J., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Hauser, J., Henigsberg, N., Maier, W., Zobel, A., Mors, O., Placentino, A. S. & 15 othersRietschel, M., Souery, D., Kozel, D., Preisig, M., Lucae, S., Binder, E. B., Aitchison, K. J., Tozzi, F., Muglia, P., Breen, G., Craig, I. W., Farmer, A. E., Mueller-Myhsok, B., McGuffin, P. & Lewis, C. M., Oct 2012, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 159B, 7, p. 859-868 10 p.Research output: Contribution to journal › Article

Genetic Predictors of Response to Serotonergic and Noradrenergic Antidepressants in Major Depressive Disorder: A Genome-Wide Analysis of Individual-Level Data and a Meta-AnalysisTansey, K. E., Guipponi, M., Perroud, N., Bondolfi, G., Domenici, E., Evans, D., Hall, S. K., Hauser, J., Henigsberg, N., Hu, X., Jerman, B., Maier, W., Mors, O., O'Donovan, M., Peters, T. J., Placentino, A., Rietschel, M., Souery, D., Aitchison, K. J., Craig, I. & 10 othersFarmer, A., Wendland, J. R., Malafosse, A., Holmans, P., Lewis, G., Lewis, C. M., Stensbol, T. B., Kapur, S., McGuffin, P. & Uher, R., Oct 2012, In : PL o S Medicine. 9, 10, p. - 10 p., e1001326.Research output: Contribution to journal › Article

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypesWebb, B. T., Guo, A-Y., Maher, B. S., Zhao, Z., van den Oord, E. J., Kendler, K. S., Riley, B. P., Gillespie, N. A., Prescott, C. A., Middeldorp, C. M., Willemsen, G., de Geus, E. J. C., Hottenga, J-J., Boomsma, D. I., Slagboom, E. P., Wray, N. R., Montgomery, G. W., Martin, N. G., Wright, M. J., Heath, A. C. & 15 othersMadden, P. A., Gelernter, J., Knowles, J. A., Hamilton, S. P., Weissman, M. M., Fyer, A. J., Huezo-Diaz, P., McGuffin, P., Farmer, A., Craig, I. W., Lewis, C., Sham, P., Crowe, R. R., Flint, J. & Hettema, J. M., Oct 2012, In : European Journal of Human Genetics. 20, 10, p. 1078-1084 7 p.Research output: Contribution to journal › Article

Non-random dropout and the relative efficacy of escitalopram and nortriptyline in treating major depressive disorderPower, R., Muthén, B., Henigsberg, N., Mors, O., Placentino, A., Mendlewicz, J., Maier, W., McGuffin, P., Lewis, C. M. & Uher, R., Oct 2012, In : Journal of Psychiatric Research. 46, 10, p. 1333-1338 6 p.Research output: Contribution to journal › Article

Visual analysis of geocoded twin data puts nature and nurture on the mapDavis, O. S. P., Haworth, C. M. A., Lewis, C. M. & Plomin, R., Sep 2012, In : Molecular Psychiatry. 17, 9, p. 867-874 8 p.Research output: Contribution to journal › Article

Effect of communicating DNA based risk assessments for Crohn's disease on smoking cessation: randomised controlled trialHollands, G. J., Whitwell, S. C. L., Parker, R. A., Prescott, N. J., Forbes, A., Sanderson, J., Mathew, C. G., Lewis, C. M., Watts, S., Sutton, S., Armstrong, D., Kinmonth, A. L., Prevost, A. T. & Marteau, T. M., 20 Jul 2012, In : British Medical Journal. 345, 7870, 12 p., e4708.Research output: Contribution to journal › Article

Methotrexate polyglutamates as a marker of patient compliance and clinical response in psoriasis: a single-centre prospective studyWoolf, R. T., West, S. L., Arenas-Hernandez, M., Hare, N., van Ton, A. M. P., Lewis, C. M., Marinaki, A. M., Barker, J. N. W. N. & Smith, C. H., Jul 2012, In : British Journal of Dermatology. 167, 1, p. 165-173 9 p.Research output: Contribution to journal › Article

Depressive disorder moderates the effect of the FTO gene on body mass indexRivera Sanchez, M., Cohen-Woods, S., Kapur, K., Breen, G., Ng, M. Y., Butler, A. W., Craddock, N., Gill, M., Korszun, A., Maier, W., Mors, O., Owen, M. J., Preisig, M., Bergmann, S., Tozzi, F., Rice, J., Rietschel, M., Rucker, J., Schosser, A., Aitchison, K. J. & 5 othersUher, R., Craig, I. W., Lewis, C. M., Farmer, A. E. & McGuffin, P., Jun 2012, In : Molecular Psychiatry. 17, 6, p. 604-611 8 p., N/A.Research output: Contribution to journal › Article

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid ArthritisGerlag, D. M., Raza, K., van Baarsen, L. G. M., Brouwer, E., Buckley, C. D., Burmester, G. R., Gabay, C., Catrina, A. I., Cope, A. P., Cornelis, F., Dahlqvist, S. R., Emery, P., Eyre, S., Finckh, A., Gay, S., Hazes, J. M., van der Helm-van Mil, A., Huizinga, T. W. J., Klareskog, L., Kvien, T. K. & 9 othersLewis, C., Machold, K. P., Ronnelid, J., van Schaardenburg, D., Schett, G., Smolen, J. S., Thomas, S., Worthington, J. & Tak, P. P., May 2012, In : Annals of the Rheumatic Diseases. 71, 5, p. 638 - 641 4 p.Research output: Contribution to journal › Article

Therapygenetics: the 5HTTLPR and response to psychological therapyEley, T. C., Hudson, J. L., Creswell, C., Tropeano, M., Lester, K. J., Cooper, P., Farmer, A., Lewis, C. M., Lyneham, H. J., Rapee, R. M., Uher, R., Zavos, H. M. S. & Collier, D. A., Mar 2012, In : Molecular Psychiatry. 17, 3, p. 236 - 237 2 p.Research output: Contribution to journal › Letter

AVPR1A and SLC6A4 Polymorphisms in Choral Singers and Non-Musicians: A Gene Association StudyMorley, A. P., Narayanan, M., Mines, R., Molokhia, A., Baxter, S., Craig, G., Lewis, C. M. & Craig, I., 22 Feb 2012, In : PL o S One . 7, 2, p. - 7 p., e31763.Research output: Contribution to journal › Article

Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP projectPerroud, N., Uher, R., Ng, M. Y. M., Guipponi, M., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Gennarelli, M., Rietschel, M., Souery, D., Dernovsek, M. Z., Stamp, A. S., Lathrop, M., Farmer, A., Breen, G., Aitchison, K. J., Lewis, C. M., Craig, I. W. & McGuffin, P., Feb 2012, In : PHARMACOGENOMICS JOURNAL. 12, 1, p. 68 - 77 10 p.Research output: Contribution to journal › Article

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learnedWray, N. R., Pergadia, M. L., Blackwood, D. H. R., Penninx, B. W. J. H., Gordon, S. D., Nyholt, D. R., Ripke, S., MacIntyre, D. J., McGhee, K. A., Maclean, A. W., Smit, J. H., Hottenga, J. J., Willemsen, G., Middeldorp, C. M., de Geus, E. J. C., Lewis, C. M., McGuffin, P., Hickie, I. B., van den Oord, E. J. C. G., Liu, J. Z. & 12 othersMacgregor, S., McEvoy, B. P., Byrne, E. M., Medland, S. E., Statham, D. J., Henders, A. K., Heath, A. C., Montgomery, G. W., Martin, N. G., Boomsma, D. I., Madden, P. A. F. & Sullivan, P. F., Jan 2012, In : Molecular Psychiatry. 17, 1, p. 36 - 48 13 p.Research output: Contribution to journal › Article

A mega-analysis of genome-wide association studies for major depressive disorderMajor Depressive Disorder Working Group of the Psychiatric GWAS Consortium, 2012, In : Molecular Psychiatry. 18, 4, p. 497-511 15 p.Research output: Contribution to journal › Article

Introduction to genetic association studiesLewis, C. M. & Knight, J., 2012, In : Cold Spring Harbor protocols. 2012, 3, p. 297-306 10 p.Research output: Contribution to journal › Article

Response to the letter from Dr. Maher and colleagues re. Linkage on SuicidalityButler, A. W., Lewis, C. M., Breen, G. & McGuffin, P., Dec 2011, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 156, 7, p. 864-5, 866-7 4 p.Research output: Contribution to journal › Article

Population-specific genetic associations with oesophageal squamous cell carcinoma in South AfricaBye, H., Prescott, N. J., Matejcic, M., Rose, E., Lewis, C. M., Parker, M. I. & Mathew, C. G., 16 Sep 2011, In : Carcinogenesis. 32, 12, p. 1855-1861 7 p.Research output: Contribution to journal › Article

Modelling the Effects of Penetrance and Family Size on Rates of Sporadic and Familial DiseaseAl-Chalabi, A. & Lewis, C. M., Sep 2011, In : Human Heredity. 71, 4, p. 281 - 288 8 p.Research output: Contribution to journal › Article

No Association Between a Common Single Nucleotide Polymorphism, rs4141463, in the MACROD2 Gene and Autism Spectrum DisorderCurran, S., Bolton, P., Rozsnyai, K., Chiocchetti, A., Klauck, S. M., Duketis, E., Poustka, F., Schlitt, S., Freitag, C. M., Lee, I., Muglia, P., Poot, M., Staal, W., de Jonge, M. V., Ophoff, R. A., Lewis, C., Skuse, D., Mandy, W., Vassos, E., Fossdal, R. & 6 othersMagnusson, P., Hreidarsson, S., Saemundsen, E., Stefansson, H., Stefansson, K. & Collier, D., Sep 2011, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 156, 6, p. 633 - 639 7 p.Research output: Contribution to journal › Article

A genome-wide significant linkage for severe depression on chromosome 3: the depression network studyBreen, G., Webb, B. T., Butler, A. W., van den Oord, E. J. C. G., Tozzi, F., Craddock, N., Gill, M., Korszun, A., Maier, W., Middleton, L., Mors, O., Owen, M. J., Cohen-Woods, S., Perry, J., Galwey, N. W., Upmanyu, R., Craig, I., Lewis, C. M., Ng, M., Brewster, S. & 8 othersPreisig, M., Rietschel, M., Jones, L., Knight, J., Rice, J., Muglia, P., Farmer, A. E. & McGuffin, P., Aug 2011, In : The American Journal of Psychiatry. 168, 8, p. 840 - 847 8 p.Research output: Contribution to journal › Article

Precipitating and perpetuating factors of rheumatoid arthritis immunopathology - linking the triad of genetic predisposition, environmental risk factors and autoimmunity to disease pathogenesisScott, I. C., Steer, S., Lewis, C. M. & Cope, A. P., Aug 2011, In : BEST PRACTICE AND RESEARCH CLINICAL RHEUMATOLOGY. 25, 4, p. 447 - 468 22 p.Research output: Contribution to journal › Article

The Neuronal Transporter Gene SLC6A15 Confers Risk to Major DepressionKohli, M. A., Lucae, S., Saemann, P. G., Schmidt, M. V., Demirkan, A., Hek, K., Czamara, D., Alexander, M., Salyakina, D., Ripke, S., Hoehn, D., Specht, M., Menke, A., Hennings, J., Heck, A., Wolf, C., Ising, M., Schreiber, S., Czisch, M., Mueller, M. B. & 19 othersUhr, M., Bettecken, T., Becker, A., Schramm, J., Rietschel, M., Maier, W., Bradley, B., Ressler, K. J., Noethen, M. M., Cichon, S., Craig, I. W., Breen, G., Lewis, C. M., Hofman, A., Tiemeier, H., van Duijn, C. M., Holsboer, F., Mueller-Myhsok, B. & Binder, E. B., 28 Apr 2011, In : Neuron. 70, 2, p. 252 - 265 14 p.Research output: Contribution to journal › Article

Depressive disorder moderates the effect of the FTO gene on body mass index.Rivera, M., Cohen-Woods, S., Kapur, K., Breen, G., Ng, M. Y., Butler, A. W., Craddock, N., Gill, M., Korszun, A., Maier, W., Mors, O., Owen, M. J., Preisig, M., Bergmann, S., Tozzi, F., Rice, J., Rietschel, M., Rucker, J., Schosser, A., Aitchison, K. J. & 5 othersUher, R., Craig, I. W., Lewis, C. M., Farmer, A. E. & McGuffin, P., 1 Apr 2011, In : Molecular Psychiatry. 17, 6, p. 604-611 8 p.Research output: Contribution to journal › Article

EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing unitsKam-Thong, T., Czamara, D., Tsuda, K., Borgwardt, K., Lewis, C. M., Erhardt-Lehmann, A., Hemmer, B., Rieckmann, P., Daake, M., Weber, F., Wolf, C., Ziegler, A., Puetz, B., Holsboer, F., Schoelkopf, B. & Mueller-Myhsok, B., Apr 2011, In : European Journal of Human Genetics. 19, 4, p. 465 - 471 7 p.Research output: Contribution to journal › Article

Convergent Animal and Human Evidence Suggests a Role of PPM1A Gene in Response to Antidepressants

Malki, K., Uher, R., Paya-Cano, J., Binder, E., Rietschel, M., Zobel, A., Mors, O., Hauser, J., Henigsberg, N., Jerman, B., Souery, D., Placentino, A., Ng, M. Y., Cohen-Woods, S., Sluyter, F., Farmer, A., Aitchison, K. J., Craig, I. W., Lewis, C. M., McGuffin, P. & 1 othersSchalkwyk, L. C., 15 Feb 2011, In : Biological psychiatry. 69, 4, p. 360 - 365 6 p.Research output: Contribution to journal › Article

Exome localization of complex disease association signalsLehne, B., Lewis, C. M. & Schlitt, T., 1 Feb 2011, In : BMC GENOMICS. 12, 92.Research output: Contribution to journal › Article

The Cognitive Impact of the ANK3 Risk Variant for Bipolar Disorder: Initial Evidence of Selectivity to Signal Detection during Sustained AttentionRuberto, G., Vassos, E., Lewis, C. M., Tatarelli, R., Girardi, P., Collier, D. & Frangou, S., 31 Jan 2011, In : PL o S One . 6, 1, p. N/A 7 p., e16671.Research output: Contribution to journal › Article

Trial Protocol: Communicating DNA-based risk assessments for Crohn's disease: a randomised controlled trial assessing impact upon stopping smokingWhitwell, S. C. L., Mathew, C. G., Lewis, C. M., Forbes, A., Watts, S., Sanderson, J., Hollands, G. J., Prevost, A. T., Armstrong, D., Kinmonth, A. L., Sutton, S. & Marteau, T. M., 19 Jan 2011, In : BMC PUBLIC HEALTH. 11, 44.Research output: Contribution to journal › Article

Effect of ethnicity on the hypnotic and cardiovascular characteristics of propofol inductionNatarajan, A., Strandvik, G. F., Pattanayak, R., Chakithandy, S., Passalacqua, A. M., Lewis, C. M. & Morley, A. P., Jan 2011, In : Anaesthesia. 66, 1, p. 15 - 19 5 p.Research output: Contribution to journal › Article

Replication of association of 3p21.1 with susceptibility to bipolar disorder but not major depressionBreen, G., Lewis, C. M., Vassos, E., Pergadia, M. L., Blackwood, D. H. R., Boomsma, D. I., Penninx, B., Sullivan, P. F., Pedroso, I., Collier, D. & McGuffin, P., Jan 2011, In : Nature Genetics. 43, 1, p. 3 - 5 3 p.Research output: Contribution to journal › Letter

Association of a deletion of GSTT2B with an altered risk of oesophageal squamous cell carcinoma in a South African population: a case-control studyMatejcic, M., Li, D., Prescott, N. J., Lewis, C. M., Mathew, C. G. & Parker, M. I., 2011, In : PLoS ONE. 6, 12, e29366.Research output: Contribution to journal › Article

From SNPs to Genes: Disease Association at the Gene LevelLehne, B., Lewis, C. M. & Schlitt, T., 2011, In : PL o S One . 6, 6, e20133.Research output: Contribution to journal › Article

Genomewide Association Scan of Suicidal Thoughts and Behaviour in Major DepressionSchosser, A., Butler, A. W., Ising, M., Perroud, N., Uher, R., Ng, M. Y., Cohen-Woods, S., Craddock, N., Owen, M. J., Korszun, A., Jones, L., Jones, I., Gill, M., Rice, J. P., Maier, W., Mors, O., Rietschel, M., Lucae, S., Binder, E. B., Preisig, M. & 10 othersPerry, J., Tozzi, F., Muglia, P., Aitchison, K. J., Breen, G., Craig, I. W., Farmer, A. E., Mueller-Myhsok, B., McGuffin, P. & Lewis, C. M., 2011, In : PL o S One . 6, 7, e20690.Research output: Contribution to journal › Article

A Genomewide Linkage Study on Suicidality in Major Depressive Disorder Confirms Evidence for Linkage to 2p12Butler, A. W., Breen, G., Tozzi, F., Craddock, N., Gill, M., Korszun, A., Maier, W., Middleton, L. T., Mors, O., Owen, M. J., Perry, J., Preisig, M., Rice, J. P., Rietschel, M., Jones, L., Farmer, A. E., Lewis, C. M. & McGuffin, P., Dec 2010, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 158B, 8, p. 1465 - 1473 9 p.Research output: Contribution to journal › Article

The Influence of Duration of Fluid Abstinence on Hypotension During Propofol InductionMorley, A. P., Nalla, B. P., Vamadevan, S., Strandvik, G., Natarajan, A., Prevost, A. T. & Lewis, C. M., Dec 2010, In : Anesthesia and Analgesia. 111, 6, p. 1373 - 1377 5 p.Research output: Contribution to journal › Article

Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association studyShatunov, A., Mok, K., Newhouse, S., Weale, M. E., Smith, B., Vance, C., Johnson, L., Veldink, J. H., van Es, M. A., van den Berg, L. H., Robberecht, W., Van Damme, P., Hardiman, O., Farmer, A. E., Lewis, C. M., Butler, A. W., Abel, O., Andersen, P. M., Fogh, I., Silani, V. & 17 othersChiò, A., Traynor, B. J., Melki, J., Meininger, V., Landers, J. E., McGuffin, P., Glass, J. D., Pall, H., Leigh, P. N., Hardy, J., Brown, R. H., Powell, J. F., Orrell, R. W., Morrison, K. E., Shaw, P. J., Shaw, C. E. & Al-Chalabi, A., Oct 2010, In : Lancet Neurology. 9, 10, p. 986-94 9 p.Research output: Contribution to journal › Article

Risk Categorization for Complex Disorders According to Genotype Relative Risk and Precision in Parameter EstimatesGoddard, G. H. M. & Lewis, C. M., Sep 2010, In : Genetic Epidemiology. 34, 6, p. 624 - 632 9 p.Research output: Contribution to journal › Article

Genome-Wide Association Study of Major Recurrent Depression in the UK PopulationLewis, C. M., Ng, M. Y., Butler, A. W., Cohen-Woods, S., Uher, R., Pirlo, K., Weale, M. E., Schosser, A., Paredes, U. M., Rivera Sanchez, M., Craddock, N., Owen, M. J., Jones, L., Jones, I., Korszun, A., Aitchison, K. J., Shi, J., Quinn, J. P., MacKenzie, A., Vollenweider, P. & 13 othersWaeber, G., Heath, S., Lathrop, M., Muglia, P., Barnes, M. R., Whittaker, J. C., Tozzi, F., Holsboer, F., Preisig, M., Farmer, A. E., Breen, G., Craig, I. W. & McGuffin, P., 1 Aug 2010, In : The American Journal of Psychiatry. 167, 8, p. 949 - 957 9 p., N/A.Research output: Contribution to journal › Article

Penetrance for copy number variants associated with schizophreniaVassos, E., Collier, D. A., Holden, S., Patch, C., Rujescu, D., St Clair, D. & Lewis, C. M., 29 Jun 2010, In : Human Molecular Genetics. 19, 17, p. 3477 - 3481 5 p., ddq259.Research output: Contribution to journal › Article

Meta-analysis of 20 genome-wide linkage studies evidenced new regions linked to asthma and atopyBouzigon, E., Forabosco, P., Koppelman, G. H., Cookson, W. O. C. M., Dizier, M-H., Duffy, D. L., Evans, D. M., Ferreira, M. A. R., Kere, J., Laitinen, T., Malerba, G., Meyers, D. A., Moffatt, M., Martin, N. G., Ng, M. Y., Pignatti, P. F., Wjst, M., Kauffmann, F., Demenais, F. & Lewis, C. M., Jun 2010, In : European Journal of Human Genetics. 18, 6, p. 700 - 706 7 p.Research output: Contribution to journal › Article

Genome-Wide Pharmacogenetics of Antidepressant Response in the GENDEP ProjectUher, R., Perroud, N., Ng, M. Y. M., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Zagar, T., Czerski, P. M., Jerman, B., Larsen, E. R., Schulze, T. G., Zobel, A., Cohen-Woods, S., Pirlo, K., Butler, A. W., Muglia, P. & 8 othersBarnes, M. R., Lathrop, M., Farmer, A., Breen, G., Aitchison, K. J., Craig, I., Lewis, C. M. & McGuffin, P., May 2010, In : The American Journal of Psychiatry. 167, 5, p. 555-564 10 p.Research output: Contribution to journal › Article

Delta-Centralization Fails to Control for Population Stratification in Genetic Association StudiesDadd, T., Lewis, C. M. & Weale, M. E., Apr 2010, In : Human Heredity. 69, 4, p. 285 - 294 10 p.Research output: Contribution to journal › Article

COMT but not serotonin-related genes modulates the influence of childhood abuse on anger traitsPerroud, N., Jaussent, I., Guillaume, S., Bellivier, F., Baud, P., Jollant, F., Leboyer, M., Lewis, C. M., Malafosse, A. & Courtet, P., Mar 2010, In : Genes, Brain and Behavior. 9, 2, p. 193 - 202 10 p.Research output: Contribution to journal › Article

Independent and population-specific association of risk variants at the IRGM locus with Crohn's diseasePrescott, N. J., Dominy, K. M., Kubo, M., Lewis, C. M., Fisher, S. A., Redon, R., Huang, N., Stranger, B. E., Blaszczyk, K., Hudspith, B., Parkes, G., Hosono, N., Yamazaki, K., Onnie, C. M., Forbes, A., Dermitzakis, E. T., Nakamura, Y., Mansfield, J. C., Sanderson, J., Hurles, M. E. & 2 othersRoberts, R. G. & Mathew, C. G., 27 Jan 2010, In : Human Molecular Genetics. 19, 9, p. 1828 - 1839 12 p., ddq041.Research output: Contribution to journal › Article

Genetic Predictors of Increase in Suicidal Ideation During Antidepressant Treatment in the GENDEP ProjectPerroud, N., Aitchison, K. J., Uher, R., Smith, R., Huezo-Diaz, P., Marusic, A., Maier, W., Mors, O., Placentino, A., Henigsberg, N., Rietschel, M., Hauser, J., Souery, D., Kapelski, P., Bonvicini, C., Zobel, A., Jorgensen, L., Petrovic, A., Kalember, P., Schulze, T. G. & 6 othersGupta, B., Gray, J., Lewis, C. M., Farmer, A. E., McGuffin, P. & Craig, I., Nov 2009, In : Neuropsychopharmacology. 34, 12, p. 2517 - 2528 12 p.Research output: Contribution to journal › Article

Searching for Genotype-Phenotype Structure: Using Hierarchical Log-Linear Models in Crohn DiseaseChapman, J. M., Onnie, C. M., Prescott, N. J., Fisher, S. A., Mansfield, J. C., Mathew, C. G., Lewis, C. M., Verzilli, C. J. & Whittaker, J. C., 8 Aug 2009, In : American Journal of Human Genetics. 84, 2, p. 178 - 187 10 p.Research output: Contribution to journal › Article

Genetic predictors of response to antidepressants in the GENDEP projectUher, R., Huezo-Diaz, P., Perroud, N., Smith, R., Rietschel, M., Mors, O., Hauser, J., Maier, W., Kozel, D., Henigsberg, N., Barreto, M., Placentino, A., Dernovsek, M. Z., Schulze, T. G., Kalember, P., Zobel, A., Czerski, P. M., Larsen, E. R., Souery, D., Giovannini, C. & 6 othersGray, J. M., Lewis, C. M., Farmer, A., Aitchison, K. J., McGuffin, P. & Craig, I., Aug 2009, In : PHARMACOGENOMICS JOURNAL. 9, 4, p. 225 - 233 9 p.Research output: Contribution to journal › Article

Meta-analysis of 32 genome-wide linkage studies of schizophreniaNg, M. Y. M., Levinson, D. F., Faraone, S. V., Suarez, B. K., DeLisi, L. E., Arinami, T., Riley, B., Paunio, T., Pulver, A. E., Holmans, P. A., Escamilla, M., Wildenauer, D. B., Williams, N. M., Laurent, C., Mowry, B. J., Brzustowicz, L. M., Maziade, M., Sklar, P., Garver, D. L., Abecasis, G. R. & 61 othersLerer, B., Fallin, M. D., Gurling, H. M. D., Gejman, P. V., Lindholm, E., Moises, H. W., Byerley, W., Wijsman, E. M., Forabosco, P., Tsuang, M. T., Hwu, H-G., Okazaki, Y., Kendler, K. S., Wormley, B., Fanous, A., Walsh, D., O'Neill, F. A., Peltonen, L., Nestadt, G., Lasseter, V. K., Liang, K. Y., Papadimitriou, G. M., Dikeos, D. G., Schwab, S. G., Owen, M. J., O'Donovan, M. C., Norton, N., Hare, E., Raventos, H., Nicolini, H., Albus, M., Maier, W., Nimgaonkar, V. L., Terenius, L., Mallet, J., Jay, M., Godard, S., Nertney, D., Alexander, M., Crowe, R. R., Silverman, J. M., Bassett, A. S., Roy, M-A., Merette, C., Pato, C. N., Pato, M. T., Roos, J. L., Kohn, Y., Amann-Zalcenstein, D., Kalsi, G., McQuillin, A., Curtis, D., Brynjolfson, J., Sigmundsson, T., Petursson, H., Sanders, A. R., Duan, J., Jazin, E., Myles-Worsley, M., Karayiorgou, M. & Lewis, C. M., Aug 2009, In : Molecular Psychiatry. 14, 8, p. 774 - 785 12 p.Research output: Contribution to journal › Article

Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel diseaseSmith, M. A., Marinaki, A. M., Arenas, M., Shobowale-Bakre, M., Lewis, C. M., Ansari, A., Duley, J. & Sanderson, J. D., Aug 2009, In : Alimentary Pharmacology and Therapeutics. 30, 4, p. 375 - 384 10 p.Research output: Contribution to journal › Article

Meta-analysis of linkage studies for Alzheimer's disease-A web resourceButler, A. W., Ng, M. Y. M., Hamshere, M. L., Forabosco, P., Wroe, R., Al-Chalabi, A., Lewis, C. M. & Powell, J. F., Jul 2009, In : Neurobiology of Aging. 30, 7, p. 1037 - 1047 11 p., N/A.Research output: Contribution to journal › Article

Genomewide association studies: history, rationale, and prospects for psychiatric disorders.Psychiatric GWAS Consortium Coordinating Committee & Lewis, C., May 2009, In : The American Journal of Psychiatry. 166, 5, p. 540 - 556 17 p.Research output: Contribution to journal › Literature review

Investigation of Crohn's Disease Risk Loci in Ulcerative Colitis Further Defines Their Molecular RelationshipAnderson, C. A., Massey, D. C. O., Barrett, J. C., Prescott, N. J., Tremelling, M., Fisher, S. A., Gwilliam, R., Jacob, J., Nimmo, E. R., Drummond, H., Lees, C. W., Onnie, C. M., Hanson, C., Blaszczyk, K., Ravindrarajah, R., Hunt, S., Varma, D., Hammond, N., Lewis, G., Attlesey, H. & 13 othersWatkins, N., Ouwehand, W., Strachan, D., McArdle, W., Lewis, C. M., Lobo, A., Sanderson, J., Jewell, D. P., Deloukas, P., Mansfield, J. C., Mathew, C. G., Satsangi, J. & Parkes, M., Feb 2009, In : Gastroenterology. 136, 2, p. 523 - 529 7 p.Research output: Contribution to journal › Article

A Critical Evaluation of Genomic Control Methods for Genetic Association StudiesDadd, T., Weale, M. E. & Lewis, C. M., 2009, In : Genetic Epidemiology. 33, 4, p. 290 - 298 9 p.Research output: Contribution to journal › Article

Advances in the genetics of schizophrenia: will high-copy number variants be useful in clinical gentics or diagnostics?Collier, D. A., Vassos, E., Holden, S., Patch, C., McGuire, P. & Lewis, C., 2009, In : F1000 medicine reports. 1, 6 p., 61.Research output: Contribution to journal › Article

Meta-Analysis of Genome-Wide Linkage Studies in Celiac DiseaseForabosco, P., Neuhausen, S. L., Greco, L., Naluai, A. T., Wijmenga, C., Saavalainen, P., Houlston, R. S., Ciclitira, P. J., Babron, M-C. & Lewis, C. M., 2009, In : Human Heredity. 68, 4, p. 223 - 230 8 p.Research output: Contribution to journal › Article

Meta-analysis of genome-wide linkage studies across autoimmune diseasesForabosco, P., Bouzigon, E., Ng, M. Y., Hermanowski, J., Fisher, S. A., Criswell, L. A. & Lewis, C. M., 2009, In : European Journal of Human Genetics. 17, 2, p. 236 - 243 8 p.Research output: Contribution to journal › Article

Meta-Analysis of Genome-Wide Linkage Scans of Attention Deficit Hyperactivity DisorderZhou, K., Dempfle, A., Arcos-Burgos, M., Bakker, S. C., Banaschewski, T., Biederman, J., Buitelaar, J., Castellanos, F. X., Doyle, A., Ebstein, R. P., Ekholm, J., Forabosco, P., Franke, B., Freitag, C., Friedel, S., Gill, M., Hebebrand, J., Hinney, A., Jacob, C., Lesch, K. P. & 32 othersLoo, S. K., Lopera, F., McCracken, J. T., McGough, J. J., Meyer, J., Mick, E., Miranda, A., Muenkel, M., Mulas, F., Nelson, S. F., Nguyen, T. T., Oades, R. D., Ogdie, M. N., Palacio, J. D., Pineda, D., Reif, A., Renner, T. J., Roeyers, H., Romanos, M., Rothenberger, A., Schaefer, H., Sergeant, J., Sinke, R. J., Smalley, S. L., Sonuga-Barke, E., Steinhausen, H-C., van der Meulen, E., Walitza, S., Warnke, A., Lewis, C. M., Faraone, S. V. & Asherson, P., 5 Dec 2008, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 147B, 8, p. 1392 - 1398 7 p.Research output: Contribution to journal › Article

Methyl-CpG-binding protein 2 polymorphisms and vulnerability to autismLoat, C. S., Curran, S., Lewis, C. M., Duvall, J., Geschwind, D., Bolton, P. & Craig, I. W., Oct 2008, In : Genes, Brain and Behavior. 7, 7, p. 754 - 760 7 p.Research output: Contribution to journal › Article

Power of genetic association studies in the presence of linkage disequilibrium and allelic heterogeneityFisher, S. A. & Lewis, C. M., Oct 2008, In : Human Heredity. 66, 4, p. 210 - 222 13 p.Research output: Contribution to journal › Article

Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel diseaseAnsari, A., Arenas, M., Greenfield, S. M., Morris, D., Lindsay, J., Gilshenan, K., Smith, M., Lewis, C., Marinaki, A., Duley, J. & Sanderson, J., Oct 2008, In : Alimentary Pharmacology and Therapeutics. 28, 8, p. 973 - 983 11 p.Research output: Contribution to journal › Article

Comprehensive association study of genetic variants in the IL-1 gene family in systemic juvenile idiopathic arthritisStock, C. J. W., Ogilvie, E. M., Samuel, J. M., Fife, M., Lewis, C. M. & Woo, P., Jun 2008, In : GENES AND IMMUNITY. 9, 4, p. 349 - 357 9 p.Research output: Contribution to journal › Article

Ectopic Maxillary Canines: Segregation Analysis and a Twin StudyCamilleri, S., Lewis, C. M. & McDonald, F., Jun 2008, In : Journal of Dental Research. 87, 6, p. 580-583 4 p.Research output: Contribution to journal › Article

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's diseaseFisher, S. A., Tremelling, M., Anderson, C. A., Gwilliam, R., Bumpstead, S., Prescott, N. J., Nimmo, E. R., Massey, D., Berzuini, C., Johnson, C., Barrett, J. C., Cummings, F. R., Drummond, H., Lees, C. W., Onnie, C. M., Hanson, C. E., Blaszczyk, K., Inouye, M., Ewels, P., Ravindrarajah, R. & 17 othersKeniry, A., Hunt, S., Carter, M., Watkins, N., Ouwehand, W., Lewis, C. M., Cardon, L., The Wellcome Trust Case Control Consortium, Lobo, A., Forbes, A., Sanderson, J., Jewell, D. P., Mansfield, J. C., Deloukas, P., Mathew, C. G., Parkes, M. & Satsangi, J., Jun 2008, In : Nature Genetics. 40, 6, p. 710-712 3 p.Research output: Contribution to journal › Article

The effect of pre-operative anxiety on induction of anaesthesia with propofolMorley, A. P., Papageorgiou, C. H., Marinaki, A. M., Cooper, D. J. & Lewis, C. M., May 2008, In : Anaesthesia. 63, 5, p. 467 - 473 7 p.Research output: Contribution to journal › Article

Diverse effects of the CARD15 and IBD5 loci on clinical phenotype in 630 patients with Crohn's diseaseOnnie, C. M., Fisher, S. A., Prescott, N. J., Mirza, M. M., Green, P., Sanderson, J., Forbes, A., Lewis, C. M. & Mathew, C. G., Jan 2008, In : European Journal of Gastroenterology and Hepatology. 20, 1, p. 37-45 9 p.Research output: Contribution to journal › Article

An increased frequency of the 5A allele in the promoter region of the MMP3 gene is associated with abdominal aortic aneurysmsDeguara, J., Burnand, KG., Berg, J., Green, P., Lewis, CM., Chinien, G., Waltham, M., Taylor, P., Stern, RF., Solomon, E. & Smith, A., 15 Dec 2007, In : Human Molecular Genetics. 16, 24, p. 3002 - 3007 6 p.Research output: Contribution to journal › Article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variantsBreen, G. D., Collier, D. A., Elkin, A. C., Farmer, A. E., Williamson, R. J., McGuffin, P., Dobson, R. J. B., Fisher, S. A., Lewis, C. M., Onnie, C. M., Prescott, N. J., Sanderson, J., Matthew, C. G. & St Clair, D., Nov 2007, In : Nature Genetics. 39, 11, p. 1329-1337 9 p.Research output: Contribution to journal › Article

Apolipoprotein E polymorphisms influence effect of pravastatin on survival after myocardial infarction in a Mediterranean population: the GISSI-Prevenzione studyChiodini, B. D., Franzosi, M. G., Barlera, S., Signorini, S., Lewis, C. M., D'Orazio, A., Mocarelli, P., Nicolis, E., Marchioli, R. & Tognoni, G., Aug 2007, In : European Heart Journal. 28, 16, p. 1977 - 1983 7 p.Research output: Contribution to journal › Article

Polymorphisms in folate, pyrinidine, and purine metabolism are associated with efficacy and tixicity of methotrexate in psoriasis.Campalani, E., Arenas, M., Marinaki, AM., Lewis, CM., Barker, JNWN. & Smith, CH., Aug 2007, In : Journal of Investigative Dermatology. 127, 8, p. 1860 - 1867 8 p.Research output: Contribution to journal › Article

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibilityParkes, M., Barrett, J. C., Prescott, N. J., Tremelling, M., Anderson, C. A., Fisher, S. A., Roberts, R. G., Nimmo, E. R., Cummings, F. R., Soars, D., Drummond, H., Lees, C. W., Khawaja, S. A., Bagnall, R., Burke, D. A., Todhunter, C. E., Ahmad, T., Onnie, C. M., McArdle, W., Strachan, D. & 11 othersBethel, G., Bryan, C., Lewis, C. M., Deloukas, P., Forbes, A., Sanderson, J., Jewell, D. P., Satsangi, J., Mansfield, J. C., Cardon, L. & Mathew, C. G., Jul 2007, In : Nature Genetics. 39, 7, p. 830 - 832 3 p.Research output: Contribution to journal › Article

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsThe Wellcome Trust Case Control Consortium, 7 Jun 2007, In : Nature. 447, 7145, p. 661 - 678 18 p.Research output: Contribution to journal › Article

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.Zeggini, E., Weedon, MN., Lindgren, CM., Frayling, TM., Elliott, KS., Lango, H., Timpson, NJ., Perry, JR., Rayner, NW., Freathy, RM., Barrett, JC., Shields, B., Morris, AP., Ellard, S., Groves, CJ., Harries, LW., Marchini, JL., Owen, KR., Knight, B., Cardon, LR. & 12 othersWalker, M., Hitman, GA., Morris, AD., Doney, AS., Wellcome Trust Case Control Consortium (WTCCC), McCarthy, MI., Hattersley, AT., Fisher, SA., Lewis, CM., Onnie, CM., Prescott, NJ. & Mathew, CG., 1 Jun 2007, In : Science. 316, 5829, p. 1336 - 1341 6 p.Research output: Contribution to journal › Article

Meta-analysis of genome-wide linkage studies for multiple sclerosis, using an extended GSMA methodHermanowski, J., Bouzigon, E., Forabosco, P., Ng, M. Y., Fisher, S. A. & Lewis, C. M., Jun 2007, In : European Journal of Human Genetics. 15, 6, p. 703 - 710 8 p.Research output: Contribution to journal › Article

A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and 1BD5Prescott, N. J., Fisher, S. A., Franke, A., Hampe, J., Onnie, C. M., Soars, D., Bagnall, R., Mirza, M. M., Sanderson, J., Forbes, A., Mansfield, J. C., Lewis, C. M., Schreiber, S. & Mathew, C. G., May 2007, In : Gastroenterology. 132, 5, p. 1665 - 1671 7 p.Research output: Contribution to journal › Article

Combined evidence from three large British association studies rejects TUCAN/CARD8 as an IBD susceptibility geneFisher, S. A., Mirza, M. M., Onnie, C. M., Soars, D., Lewis, C. M., Prescott, N. J., Mathew, C. G., Sanderson, J., Forbes, A., Todhunter, C., Donaldson, P. & Mansfield, J., May 2007, In : Gastroenterology. 132, 5, p. 2078 - 2080 3 p.Research output: Contribution to journal › Letter

IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel diseaseTremelling, M., Cummings, F., Fisher, S. A., Mansfield, J., Gwilliam, R., Keniry, A., Nimmo, E. R., Drummond, H., Onnie, C. M., Prescott, N. J., Sanderson, J., Bredin, F., Berzuini, C., Forbes, A., Lewis, C. M., Cardon, L., Deloukas, P., Jewell, D., Mathew, C. G., Parkes, M. & 1 othersSatsangi, J., May 2007, In : Gastroenterology. 132, 5, p. 1657 - 1664 8 p.Research output: Contribution to journal › Article

Data acquisition for meta-analysis of genome-wide linkage studies using the genome search meta-analysis methodForabosco, P., Ng, M. Y. M., Bouzigon, E., Fisher, S. A., Levinson, D. F. & Lewis, C. M., Apr 2007, In : Human Heredity. 64, 1, p. 74 - 81 8 p.Research output: Contribution to journal › Article

Investigation of association of the DLG5 gene with phenotypes of inflammatory bowel disease in the British populationPearce, A. V., Fisher, S. A., Prescott, N. J., Onnie, C. M., Pattni, R., Green, P. M., Forbes, A., Mansfield, J., Sanderson, J., Schreiber, S., Lewis, C. M. & Mathew, C. G., Apr 2007, In : International Journal of Colorectal Disease. 22, 4, p. 419 - 424 6 p.Research output: Contribution to journal › Article

Determination of the genetic status of cleavage-stage human embryos by microsatellite marker analysis following multiple displacement amplificationRenwick, P. J., Lewis, C. M., Abbs, S. & Ogilvie, C. M., Mar 2007, In : Prenatal Diagnosis. 27, 3, p. 206 - 215 10 p.Research output: Contribution to journal › Article

Meta-analysis of genome-wide scans provides evidence for sex- and site-specific regulation of bone mass.Ioannidis, JPA., Ng, MY., Sham, PC., Zintzaras, E., Lewis, CM., Deng, HW., Econs, MJ., Karasik, D., Devoto, M., Kammerer, CM., Spector, T., Andrew, T., Cupples, LA., Duncan, EL., Foroud, T., Keil, DP., Koller, DL., Langdahl, B., Mitchell, BD., Peacock, M. & 9 othersRecker, R., Hui, S., Katia, S., Sol Church, K., Spotila, LD., Uitterlinden, AG., Wilson, SG., Kung, AWC. & Ralston, SH., Feb 2007, In : Journal of Bone and Mineral Research. 22, 2, p. 173 - 183 11 p.Research output: Contribution to journal › Article

Meta-analysis of genome-wide linkage studies in BMI and obesitySaunders, C. L., Chiodini, B. D., Sham, P., Lewis, C. M., Abkevich, V., Adeyemo, A. A., de Andrade, M., Arya, R., Berenson, G. S., Blangero, J., Boehnke, M., Borecki, I. B., Chagnon, Y. C., Chen, W., Comuzzie, A. G., Deng, H. W., Duggirala, R., Feitosa, M. F., Froguel, P., Hanson, R. L. & 20 othersHebebrand, J., Huezo-Dias, P., Kissebah, A. H., Li, W. D., Luke, A., Martin, L. J., Nash, M., Ohman, M., Palmer, L. J., Peltonen, L., Perola, M., Price, R. A., Redline, S., Srinivasan, S. R., Stern, M. P., Stone, S., Stringham, H., Turner, S., Wijmenga, C. & Collier, D. A., 2007, In : Obesity. 15, 9, p. 2263 - 2275 13 p.Research output: Contribution to journal › Article

Recruiting first-degree relatives for prevention research: a comparison of clinician and proband-led methods of contact in Crohn's diseaseReid, E. P., Forbes, A., Sanderson, J., Mathew, C. G., Lewis, C. & Marteau, T. M., Dec 2006, In : European Journal of Human Genetics. 14, 12, p. 1263 - 1268 6 p.Research output: Contribution to journal › Article

Meta-analysis of genome-wide linkage studies of systemic lupus erythematosusForabosco, P., Gorman, J. D., Cleveland, C., Kelly, J. A., Fisher, S. A., Ortmann, W. A., Johansson, C., Johanneson, B., Moser, K. L., Gaffney, P. M., Tsao, B. P., Cantor, R. M., arcon-Riquelme, M. E., Behrens, T. W., Harley, J. B., Lewis, C. M. & Criswell, L. A., Oct 2006, In : GENES AND IMMUNITY. 7, 7, p. 609 - 614 6 p.Research output: Contribution to journal › Article

Novel IL10 gene family associations with systemic juvenile idiopathic arthritisFife, M. S., Gutierrez, A., Ogilvie, E. M., Stock, C. J. W., Samuel, J. M., Thomson, W., Mack, L. F., Lewis, C. M. & Woo, P., 7 Sep 2006, In : Arthritis Research and Therapy. 8, 5, R148.Research output: Contribution to journal › Article

Direct or indirect association in a complex disease: The role of SLC22A4 and SLC22A5 functional variants in Crohn diseaseFisher, S. A., Hampe, J., Onnie, C. M., Daly, M. J., Curley, C., Purcell, S., Sanderson, J., Mansfield, J., Annese, V., Forbes, A., Lewis, C. M., Schreiber, S., Rioux, J. D. & Mathew, C. G., Aug 2006, In : Human Mutation. 27, 8, p. 778 - 785 8 p.Research output: Contribution to journal › Article

Sequence variation, linkage disequilibrium and association with Crohn's disease on chromosome 5q31Onnie, C., Fisher, S. A., King, K., Mirza, M., Roberts, R., Forbes, A., Sanderson, J., Lewis, C. M. & Mathew, C. G., Jul 2006, In : GENES AND IMMUNITY. 7, 5, p. 359 - 365 7 p.Research output: Contribution to journal › Article

Testing for genetic heterogeneity in the genome search meta-analysis methodLewis, C. M. & Levinson, D. E., May 2006, In : Genetic Epidemiology. 30, 4, p. 348 - 355 8 p.Research output: Contribution to journal › Article

Associations of allelic variants of the multidrug resistance gene (ABCB1 or MDR1) and inflammatory bowel disease and their effects on disease behavior: A case-control and meta-analysis studyOnnie, C. M., Fisher, S. A., Pattni, R., Sanderson, J., Forbes, A., Lewis, C. M. & Mathew, C. G., Apr 2006, In : Inflammatory Bowel Diseases. 12, 4, p. 263 - 271 9 p.Research output: Contribution to journal › Article

Mutation, selection, and evolution of the Crohn disease susceptibility gene CARD15.King, K., Sheikh, M. E., Cuthbert, A. P., Fisher, S. A., Onnie, C. M., Mirza, M. M., Pattni, R. C., Sanderson, J., Forbes, A., Mansfield, J., Lewis, C. M., Roberts, R. G. & Mathew, C. G., Jan 2006, In : Human Mutation. 27, 1, p. 44 - 54 11 p.Research output: Contribution to journal › Article

GSMA: software implementation of the genome search meta-analysis method.Pardi, F., Levinson, D. F. & Lewis, C. M., Dec 2005, In : BIOINFORMATICS. 21, 24, p. 4430 - 4431 2 p.Research output: Contribution to journal › Article

Genetic variation in the MTHFR gene influences thiopurine methyltransferase activity.Arenas, M., Simpson, G., Lewis, C. M., Shobowale-Bakre, E. M., Escuredo, E., Fairbanks, L. D., Duley, J. A., Ansari, A., Sanderson, J. D. & Marinaki, A. M., Dec 2005, In : Clinical Chemistry. 51, 12, p. 2371 - 2374 4 p.Research output: Contribution to journal › Article

SNP selection for association studies: Maximizing power across SNP choice and study size.Pardi, F., Lewis, C. M. & Whittaker, J. C., Nov 2005, In : Annals of Human Genetics. 69, 6, p. 733 - 746 14 p.Research output: Contribution to journal › Article

A general autoimmunity gene (PTPN22) is not associated with inflammatory bowel disease in a British population.Prescott, N. J., Fisher, S. A., Onnie, C., Pattni, R., Steer, S., Sanderson, J., Forbes, A., Lewis, C. M. & Mathew, C. G., Oct 2005, In : Tissue Antigens. 66, 4, p. 318 - 320 3 p.Research output: Contribution to journal › Article

Meta-analysis of genome scans of age-related macular degeneration.Fisher, S. A., Abecasis, G. R., Yasher, B. M., Zareparsi, S., Swaroop, A., Iyengar, S. K., Klein, B. E. K., Klein, R., Lee, K. E., Majewski, J., Schultz, D. W., Klein, M. L., Seddon, J. M., Santangelo, S. L., Weeks, D. E., Conley, Y. P., Mah, T. S., Schmidt, S., Haines, J. L., Pericak-Vance, M. A. & 5 othersGorin, M. B., Schulz, H. L., Pardi, F., Lewis, C. M. & Weber, B. H. F., 1 Aug 2005, In : Human Molecular Genetics. 14, 15, p. 2257 - 2264 8 p.Research output: Contribution to journal › Article

No association of the NFKB1 promoter polymorphism with ulcerative colitis in a British case control cohort.Mirza, M. M., Fisher, S. A., Onnie, C., Sanderson, J., Forbes, A., Lewis, C. M. & Mathew, C. G., Aug 2005, In : Gut. 54, 8, p. 1205 - 1206 2 p.Research output: Contribution to journal › Letter

Association of DLG5 R30Q variant with inflammatory bowel disease.Daly, M., Pearce, A. V., Farwell, L., Fisher, S. A., Latiano, A., Prescott, N. J., Forbes, A., Mansfield, J., Sanderson, J., Langelier, D., Cohen, A., Bitton, A., Wild, G., Lewis, C. M., Annese, V., Mathew, C. G. & Rioux, J. D., Jul 2005, In : European Journal of Human Genetics. 13, 7, p. 835 - 839 5 p.Research output: Contribution to journal › Article

Corneodesmosin (CDSN) gene association with psoriasis vulgaris in Caucasian but not Japanese populations.Ameen, M., Allen, M. H., Fisher, S. A., Lewis, C. M., Cuthbert, A., Kondeatis, E., Murakami, H., Nakagawa, H., Barker, J. N. W. N. & Vaughan, R., Jul 2005, In : Clinical and Experimental Dermatology. 30, 4, p. 414 - 418 5 p.Research output: Contribution to journal › Article

A common Fanconi anemia mutation in black populations of sub-Saharan AfricaMorgan, N. V., Essop, F., Demuth, I., de Ravel, T., Jansen, S., Tischkowitz, M., Lewis, C. M., Wainwright, L., Poole, J., Joenje, H., Digweed, M., Krause, A. & Mathew, C. G., 1 May 2005, In : Blood. 105, 9, p. 3542 - 3544 3 p.Research output: Contribution to journal › Article

Meta-analysis of genome-wide scans for hypertension and blood pressure in Caucasians shows evidence of susceptibility regions on chromosomes 2 and 3Koivukoski, L., Fisher, S. A., Kanninen, T., Lewis, C. M., von Wowern, F., Hunt, S., Kardia, S. L. R., Levy, D., Perola, M., Rankinen, T., Rao, D. C., Rice, T., Thiel, B. A. & Melander, O., 1 Oct 2004, In : Human Molecular Genetics. 13, 19, p. 2325 - 2332 8 p.Research output: Contribution to journal › Article

Genetics of inflammatory bowel disease: progress and prospectsMathew, C. G. & Lewis, C. M., 1 Apr 2004, In : Human Molecular Genetics. 13, REV. ISS. 1, p. R161 - R168Research output: Contribution to journal › Literature review

Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairsvan Heel, D. A., Fisher, S. A., Kirby, A., Daly, M. J., Rioux, J. D., Lewis, C. M. & Genome Scan Meta-Analysis Group of the IBD International Genetics Consortium, 1 Apr 2004, In : Human Molecular Genetics. 13, 7, p. 763 - 770 8 p.Research output: Contribution to journal › Article

Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase)Marinaki, A. M., Ansari, A., Duley, J. A., Arenas, M., Sumi, S., Lewis, C. M., Shobowale-Bakre, E. M., Escuredo, E., Fairbanks, L. D. & Sanderson, J. D., Mar 2004, In : Pharmacogenetics. 14, 3, p. 181 - 187 7 p.Research output: Contribution to journal › Article

Genetic association between EPHX1 and Crohn's disease: population stratification, genotyping error, or random chance?Cuthbert, A. P., Fisher, S. A., Lewis, C. M., Mathew, C. G., Sanderson, J. & Forbes, A., 2004, In : Gut. 53, 9, p. 1386 - 1386 1 p.Research output: Contribution to journal › Letter

Mutation in the ITPA gene predicts intolerance to azathioprineMarinaki, A. M., Duley, J. A., Arenas, M., Ansari, A., Sumi, S., Lewis, C. M., Shobowale-Bakre, M., Fairbanks, L. D. & Sanderson, J., 2004, In : NUCLEOSIDES NUCLEOTIDES AND NUCLEIC ACIDS. 23, 8-9, p. 1393 - 1397 5 p.Research output: Contribution to journal › Conference paper

SNP subset selection for genetic association studiesByng, M. C., Whittaker, J. C., Cuthbert, A. R., Mathew, C. G. & Lewis, C. M., Nov 2003, In : Annals of Human Genetics. 67, 6, p. 543 - 556 14 p.Research output: Contribution to journal › Article

The-174G allele of the interleukin-6 gene confers susceptibility to systemic arthritis in children - A multicenter study using simplex and multiplex juvenile idiopathic arthritis familiesOgilvie, E. M., Fife, M. S., Thompson, S. D., Twine, N., Tsoras, M., Moroldo, M., Fisher, S. A., Lewis, C. M., Prieur, A. M., Glass, D. N. & Woo, P., Nov 2003, In : Arthritis & Rheumatism. 48, 11, p. 3202 - 3206 5 p.Research output: Contribution to journal › Article

Meta-analysis of 4 coronary heart disease genome-wide linkage studies confirms a susceptibility locus on chromosome 3qChiodini, B. D. & Lewis, C. M., Oct 2003, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 23, 10, p. 1863 - 1868 6 p.Research output: Contribution to journal › Article

Standardization and statistical approaches to therapeutic trials in the R6/2 mouseHockly, E., Woodman, B., Mahal, A., Lewis, C. M. & Bates, G., 30 Sep 2003, In : Brain Research Bulletin. 61, 5, p. 469 - 479 11 p.Research output: Contribution to journal › Article

Genetic variation at the chromosome 16 chemokine gene cluster: Development of a strategy for association studies in complex diseaseFisher, S. A., Moody, A., Mirza, M. M., Cuthbert, A. P., Hampe, J., Macpherson, A., Sanderson, J., Forbes, A., Mansfield, J., Schreiber, S., Lewis, C. M. & Mathew, C. G., Sep 2003, In : Annals of Human Genetics. 67, 5, p. 377 - 390 14 p.Research output: Contribution to journal › Article

Two families with familial amyotrophic lateral sclerosis are linked to a novel locus on chromosome 16qRuddy, D. M., Parton, M. J., Al-Chalabi, A., Lewis, C. M., Vance, C., Smith, B. N., Leigh, P. N., Powell, J. F., Siddique, T., Meyjes, E. P., Baas, F., De Jong, V. & Shaw, C. E., 1 Aug 2003, In : American Journal of Human Genetics. 73, 2, p. 390 - 396 7 p.Research output: Contribution to journal › Article

Genome scan meta-analysis of schizophrenia and bipolar disorder, part I: Methods and power analysisLevinson, D. F., Levinson, M. D., Segurado, R. & Lewis, C. M., 1 Jul 2003, In : American Journal of Human Genetics. 73, 1, p. 17 - 33 17 p.Research output: Contribution to journal › Article

Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: SchizophreniaLewis, C. M., Levinson, D. F., Wise, L. H., DeLisi, L. E., Straub, R. E., Hovatta, I., Williams, N. M., Schwab, S. G., Pulver, A. E., Faraone, S. V., Brzustowicz, L. M., Kaufmann, C. A., Garver, D. L., Gurling, H. M. D., Lindholm, E., Coon, H., Moises, H. W., Byerley, W., Shaw, S. H., Mesen, A. & 33 othersSherrington, R., O'Neill, F. A., Walsh, D., Kendler, K. S., Ekelund, J., Paunio, T., Lonnqvist, J., Peltonen, L., O'Donovan, M. C., Owen, M. J., Wildenauer, D. B., Maier, W., Nestadt, G., Blouin, J. L., Antonarakis, S. E., Mowry, B. J., Silverman, J. M., Crowe, R. R., Cloninger, C. R., Tsuang, M. T., Malaspina, D., Harkavy-Friedman, J. M., Svrakic, D. M., Bassett, A. S., Holcomb, J., Kalsi, G., McQuillin, A., Brynjolfson, J., Sigmundsson, T., Petursson, H., Jazin, E., Zoega, T. & Helgason, T., 1 Jul 2003, In : American Journal of Human Genetics. 73, 1, p. 34 - 48 15 p.Research output: Contribution to journal › Article

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorderSegurado, R., Detera-Wadleigh, S. D., Levinson, D. F., Lewis, C. M., Gill, M., Nurnberger, J. I., Craddock, N., DePaulo, J. R., Baron, M., Gershon, E. S., Ekholm, J., Cichon, S., Turecki, G., Claes, S., Kelsoe, J. R., Schofield, P. R., Badenhop, R. F., Morissette, J., Coon, H., Blackwood, D. & 58 othersMcInnes, L. A., Foroud, T., Edenberg, H. J., Reich, T., Rice, J. P., Goate, A., McInnis, M. G., McMahon, F. J., Badner, J. A., Goldin, L. R., Bennett, P., Willour, V. L., Zandi, P. P., Liu, J. J., Gilliam, C., Juo, S. H., Berrettini, W. H., Yoshikawa, T., Peltonen, L., Lonnqvist, J., Nothen, M. M., Schumacher, J., Windemuth, C., Rietschel, M., Propping, P., Maier, W., Alda, M., Grof, P., Rouleau, G. A., Del-Favero, J., Van Broeckhoven, C., Mendlewicz, J., Adolfsson, R., Spence, M. A., Luebbert, H., Adams, L. J., Donald, J. A., Mitchell, P. B., Barden, N., Shink, E., Byerley, W., Muir, W., Visscher, P. M., Macgregor, S., Gurling, H., Kalsi, G., McQuillin, A., Escamilla, M. A., Reus, V. I., Leon, P., Freimer, N. B., Ewald, H., Kruse, T. A., Mors, O., Radhakrishna, U., Blouin, J. L., Antonarakis, S. E. & Akarsu, N., 1 Jul 2003, In : American Journal of Human Genetics. 73, 1, p. 49 - 62 14 p.Research output: Contribution to journal › Article

Genetic variation in the IGSF6 gene and lack of association with inflammatory bowel diseaseKing, K., Moody, A., Fisher, S. A., Mirza, M. M., Cuthbert, A. P., Hampe, J., Sutherland-Craggs, A., Sanderson, J., MacPherson, A. J., Forbes, A., Mansfield, J., Schreiber, S., Lewis, C. M. & Mathew, C. G., Jun 2003, In : European Journal of Immunogenetics. 30, 3, p. 187 - 190 4 p.Research output: Contribution to journal › Article

Meta-analysis of four rheumatoid arthritis genome-wide linkage studies - Confirmation of a susceptibility locus on chromosome 16Fisher, S. A., Lanchbury, J. S. & Lewis, C. M., 1 May 2003, In : Arthritis & Rheumatism. 48, 5, p. 1200 - 1206 7 p.Research output: Contribution to journal › Article

Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn diseaseMirza, M. M., Fisher, S. A., King, K., Cuthbert, A. P., Hampe, J., Sanderson, J., Mansfield, J., Donaldson, P., Macpherson, A. J. S., Forbes, A., Schreiber, S., Lewis, C. M. & Mathew, C. G., 1 Apr 2003, In : American Journal of Human Genetics. 72, 4, p. 1018 - 1022 5 p.Research output: Contribution to journal › Article

Does the occurrence of certain rare cancers indicate an inherited cancer susceptibility?Levene, S., Scott, G., Price, P., Sanderson, J., Evans, H., Taylor, C., Bass, S., Lewis, C. & Hodgson, S., Apr 2003, In : FAMILIAL CANCER. 2, 1, p. 15 - 25 11 p.Research output: Contribution to journal › Article

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's diseaseHockly, E., Richon, V. M., Woodman, B., Smith, D. L., Zhou, X. B., Rosa, E., Sathasivam, K., Ghazi-Noori, S., Mahal, A., Lowden, P. A. S., Steffan, J. S., Marsh, J. L., Thompson, L. M., Lewis, C. M., Marks, P. A. & Bates, G. P., 18 Feb 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 4, p. 2041 - 2046 6 p.Research output: Contribution to journal › Article

Development of rheumatoid arthritis is not associated with two polymorphisms in the Crohn's disease gene CARD15Steer, S., Fisher, S. A., Fife, M., Cuthbert, A., Newton, J., Wordsworth, P., Lewis, C. M., Mathew, C. G. & Lanchbury, J. S., 1 Feb 2003, In : Rheumatology. 42, 2, p. 304 - 307 4 p.Research output: Contribution to journal › Article

Genetic determinants of the thiopurine methyltransferase intermediate activity phenotype in British Asians and CaucasiansMarinaki, A. M., Arenas, M., Khan, Z. H., Lewis, C. M., Shobowale-Bakre, E. M., Escuredo, E., Fairbanks, L. D., Mayberry, J. F., Wicks, A. C., Ansari, A., Sanderson, J. & Duley, J. A., Feb 2003, In : Pharmacogenetics. 13, 2, p. 97 - 105 9 p.Research output: Contribution to journal › Article

Log odds of carrying an ancestral mutation in BRCA1 or BRCA2 for a defined personal and family history in an Ashkenazi Jewish woman (LAMBDA)Apicella, C., Andrews, L., Hodgson, S. V., Fisher, S. A., Lewis, C. M., Solomon, E., Tucker, K., Friedlander, M., Bankier, A., Southey, M. C., Venter, D. J. & Hopper, J. L., 2003, In : Breast Cancer Research. 5, 6, p. R206 - R216Research output: Contribution to journal › Article

Variance components linkage analysis for adjusted systolic blood pressure in the Framingham Heart Study .Byng, MC., Fisher, SA., Lewis, CM. & Whittaker, JC., 2003, In : BMC GENETICS. 4, p. S4 - S4Research output: Contribution to journal › Conference paper

Genetic association studies: design, analysis and interpretationLewis, C. M., Jun 2002, In : BRIEFINGS IN BIOINFORMATICS. 3, 2, p. 146 - 153 8 p.Research output: Contribution to journal › Article

Association of familial and sporadic rheumatoid arthritis with a single corticotropin-releasing hormone genomic region (8q12.3) haplotypeFife, M., Steer, S., Fisher, S., Newton, J., McKay, K., Worthington, J., Shah, C., Polley, A., Rosenthal, A., Ollier, W., Lewis, C., Wordsworth, P. & Lanchbury, J., 2002, In : Arthritis & Rheumatism. 46, 1, p. 75 - 82 8 p.Research output: Contribution to journal › Article

Environmental enrichment slows disease progression in R61/2 Huntington's disease miceHockly, E., Cordery, P. M., Woodman, B., Mahal, A., van Dellen, A., Blakemore, C., Lewis, C. M., Hannan, A. J. & Bates, G. P., 2002, In : Annals of Neurology. 51, 2, p. 235 - 242 8 p.Research output: Contribution to journal › Article

Relationship between p53 codon 72 polymorphism and susceptibility to sunburn and skin cancerMcGregor, J. M., Harwood, C. A., Brooks, L., Fisher, S. A., Kelly, D. A., O'nions, J., Young, A. R., Surentheran, T., Breuer, J., Millard, T. P., Lewis, C. M., Leigh, I. M., Storey, A. & Crook, T., 2002, In : Journal of Investigative Dermatology. 119, 1, p. 84 - 90 7 p.Research output: Contribution to journal › Article

Sex stratification of an inflammatory bowel disease genome search shows male-specific linkage to the HLA region of chromosome 6Fisher, S. A., Hampe, J., Macpherson, A. J. S., Forbes, A., Lennard-Jones, J. E., Schreiber, S., Curran, M. E., Mathew, C. G. & Lewis, C. M., 2002, In : European Journal of Human Genetics. 10, 4, p. 259 - 265 7 p.Research output: Contribution to journal › Article

The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel diseaseCuthbert, A. P., Fisher, S. A., Mirza, M. M., King, K., Hampe, J., Croucher, P. J. P., Mascheretti, S., Sanderson, J., Forbes, A., Mansfield, J., Schreiber, S., Lewis, C. M. & Mathew, C. G., 2002, In : Gastroenterology. 122, 4, p. 867 - 874 8 p.Research output: Contribution to journal › Article

The risk of subsequent primary cancers after colorectal cancer in southeast EnglandEvans, H. S., Moller, H., Robinson, D., Lewis, C. M., Bell, C. M. J. & Hodgson, S. V., 2002, In : Gut. 50, 5, p. 647 - 652 6 p.Research output: Contribution to journal › Article

Cancer risks in women with 2 breast or ovarian cancers: Clues to genetic cancer susceptibilityEvans, H. S., Lewis, C. M., Robinson, D., Bell, C. M. J., Moller, H. & Hodgson, S. V., 1 Dec 2001, In : International Journal of Cancer. 94, 5, p. 758 - 759 2 p.Research output: Contribution to journal › Article

Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populationsHampe, J., Cuthbert, A., Croucher, P. J. P., Mirza, M. M., Mascheretti, S., Fisher, S., Frenzel, H., King, K., Hasselmeyer, A., MacPherson, A. J. S., Bridger, S., van Deventer, S., Forbes, A., Nikolaus, S., Lennard-Jones, J. E., Foelsch, U. R., Krawczak, M., Lewis, C., Schreiber, S. & Mathew, C. G., 16 Jun 2001, In : The Lancet. 357, 9272, p. 1925 - 1928 4 p.Research output: Contribution to journal › Article

A candidate gene analysis of three related photosensitivity disorders: cutaneous lupus erythematosus, polymorphic light eruption and actinic prurigoMillard, T. P., Kondeatis, E., Cox, A., Wilson, A. G., Grabczynska, S. A., Carey, B. S., Lewis, C. M., Khamashta, M. A., Duff, G. W., Hughes, G. R. V., Hawk, J. L. M., McGregor, J. M. & Vaughan, R., 2001, In : British Journal of Dermatology. 145, 2, p. 229 - 236 8 p.Research output: Contribution to journal › Article

Controlling misdiagnosis errors in preimplantation genetic diagnosis: a comprehensive model encompassing extrinsic and intrinsic sources of errorLewis, C. M., Pinel, T., Whittaker, J. C. & Handyside, A. H., 2001, In : Human Reproduction. 16, 1, p. 43 - 50 8 p.Research output: Contribution to journal › Article

Detecting population outliers and null alleles in linkage data: Application to GAW12 asthma studiesFisher, S. A., Lewis, C. M. & Wise, L. H., 2001, In : Genetic Epidemiology. 21, SUPPL. 1, p. S18 - S23Research output: Contribution to journal › Conference paper

Familial clustering of polymorphic light eruption in relatives of patients with lupus erythematosus: evidence of a shared pathogenesisMillard, T. P., Lewis, C. M., Khamashta, M. A., Hughes, G. R. V., Hawk, J. L. M. & McGregor, J. M., 2001, In : British Journal of Dermatology. 144, 2, p. 334 - 338 5 p.Research output: Contribution to journal › Article

Incidence of multiple primary cancers in a cohort of women diagnosed with breast cancer in southeast EnglandEvans, H. S., Lewis, C. M., Robinson, D., Bell, C. M. J., Moller, H. & Hodgson, S. V., 2001, In : BJC: British Journal of Cancer. 84, 3, p. 435 - 440 6 p.Research output: Contribution to journal › Article

Methods to identify population outliers using genetic markers.Fisher, S. A. & Lewis, C. M., 2001, In : GENESCREEN. 1, 3, p. 125 - 129 5 p.Research output: Contribution to journal › Article

Polymorphic light eruption and the HLA DRB1*0301 extended haplotype are independent risk factors for cutaneous lupus erythematosusMillard, T. P., Kondeatis, E., Vaughan, R., Lewis, C. M., Khamashta, M. A., Hughes, G. R. V., Hawk, J. L. M. & McGregor, J. M., 2001, In : Lupus. 10, 7, p. 473 - 479 7 p.Research output: Contribution to journal › Article

Celiac disease and human leukocyte antigen genotype: Accuracy of diagnosis in self-diagnosed individuals, dosage effect, and sibling riskLewis, C., Book, L., Black, J., Sawitzke, A., Cannon-Albright, L., Zone, J. & Neuhausen, S., Jul 2000, In : Journal of Pediatric Gastroenterology and Nutrition. 31, 1, p. 22 - 27 6 p.Research output: Contribution to journal › Article

Analysis of single-nucleotide polymorphisms in the interleukin-4 receptor gene for association with inflammatory bowel diseaseOlavesen, M. G., Hampe, J., Mirza, M. M., Saiz, R., Lewis, C. M., Bridger, S., Teare, D., Easton, D. F., Herrmann, T., Scott, G., Hirst, J., Sanderson, J., Hodgson, S. V., Lee, J., MacPherson, A., Schreiber, S., Lennard-Jones, J. E., Curran, M. E. & Mathew, C. G., 2000, In : Immunogenetics. 51, 1, p. 1 - 7 7 p.Research output: Contribution to journal › Article

Association of complementation group and mutation type with clinical outcome in Fanconi anemiaEuropean Fanconi Anemia Res Grp, Guardiola, P., Lewis, C., Dokal, I., Ebell, W., Zatterale, Z., Altay, C., Poole, J., Stones, D., Kwee, M. L., van Weel-Sipman, M., Havenga, C., Morgan, N., de Winter, J., Digweed, M., Savoia, A., Pronk, J., de Ravel, T., Jansen, S., Joenje, H. & 2 othersGluckman, E. & Mathew, C. G., 2000, In : Blood. 96, 13, p. 4064 - 4070 7 p.Research output: Contribution to journal › Article

Genetic modeling of abnormal photosensitivity in families with polymorphic light eruption and actinic prurigoMcGregor, J. M., Grabczynska, S., Vaughan, R., Hawk, J. L. M. & Lewis, C. M., 2000, In : Journal of Investigative Dermatology. 115, 3, p. 471 - 476 6 p.Research output: Contribution to journal › Article

Multipoint linkage analysis of a candidate gene locus in rheumatoid arthritis demonstrates significant evidence of linkage and association with the corticotropin-releasing hormone genomic regionFife, M. S., Fisher, S. A., John, S., Worthington, J., Shah, C. J., Ollier, W. E. R., Panayi, G. S., Lewis, C. M. & Lanchbury, J. S., 2000, In : Arthritis & Rheumatism. 43, 8, p. 1673 - 1678 6 p.Research output: Contribution to journal › Article

Power of the TDT to detect association: effect of linkage disequilibrium between genetic markers and an unobserved diease mutationLewis, C. M. & Fisher, S. A., 2000, In : GENESCREEN. 1, 2, p. 69 - 71 3 p.Research output: Contribution to journal › Article

Mutation rates in humans. I. Overall and sex-specific rates obtained from a population study of hemophilia BGreen, P. M., Saad, S., Lewis, C. M. & Giannelli, F., 1999, In : American Journal of Human Genetics. 65, 6, p. 1572 - 1579 8 p.Research output: Contribution to journal › Article

The above report is produced using the following setupOrdered by: null