2010

2010.1.4413 2009

1 413

: Zhang, XB (Zhang, Xiaobin); Zhang, ZJ (Zhang, Zhijun); Sha, WW (Sha, Weiwei); Xie, CM (Xie, Chunming); Xi, GJ (Xi, Guangjun); Zhou, HH (Zhou, Honghui); Zhang, YM (Zhang, Yumei)

: Electroconvulsive therapy increases glial cell-line derived neurotrophic factor (GDNF) serum levels in patients with drug-resistant depression

: PSYCHIATRY RESEARCH, 170 (2-3): 273-275 DEC 30 2009

: English

: Article

: Electroconvulsive therapy; Glial cell-line derived neurotrophic factor; Major depressive disorder

KeyWords Plus: NERVE GROWTH-FACTOR; C6 GLIOMA-CELLS; BIPOLAR DISORDER; MAJOR DEPRESSION; GENE-EXPRESSION; BRAIN; RAT; FAMILY; EPIDEMIOLOGY; STIMULATION

: Electroconvulsive therapy (ECT) can be effective in patients with depression resistant to pharmacologic medication. We report that serum levels of glial cell-line derived neurotrophic factor (GDNF) were increased following ECT of patients with drug-resistant depression. When patients were sub-classified into ECT responders and non-responders, serum GDNF levels were significantly increased (58%) in responsive patients following ECE No significant increase was seen in non-responders. These results suggest that successful ECT may be associated with elevated serum GDNF levels. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

: [Zhang, Xiaobin; Zhang, Zhijun; Xie, Chunming; Xi, Guangjun] Southeast Univ, Affiliated ZhongDa Hosp, Dept Neurol, Nanjing 210009, Peoples R China; [Zhang, Xiaobin; Sha, Weiwei; Zhou, Honghui; Zhang, Yumei] Yangzhou Univ, Dept Psychiat, Affiliated WuTaiShan Hosp, Yangzhou 225003, Peoples R China

: Zhang, ZJ, Southeast Univ, Affiliated ZhongDa Hosp, Dept Neurol, 87 DingJiaQiao Rd, Nanjing 210009, Peoples R China.

: zhangxiaobim@163.com; zhijunzhang838@yahoo.com.cn; sww63723@sohu.com; chmixe@yahoo.com.cn; xiguangjun@163.com; zhh8@yzcn.net; zhangyumei106106@163.com

:

National Nature Science Foundation of China

30770779

30825014

Nature Science Intensive Fund

BK2006708

JiangSu Province and the National Basic Research Program of China

2007CB512308

National HIGH Technique Research and Development Program

2007AA0200Z435

This work was partially supported by the National Nature Science Foundation of China (No: 30770779; 30825014; Zhang ZJ), the Nature Science Intensive Fund (No: BK2006708: Zhang ZJ) of JiangSu Province and the National Basic Research Program of China (973 Program; No: 2007CB512308; Zhang ZJ) and the National HIGH Technique Research and Development Program (863 Program; No: 2007AA0200Z435: Zhang ZJ).

: 31

: 0

: ELSEVIER IRELAND LTD

: ELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELAND

ISSN: 0165-1781

DOI: 10.1016/j.psychres.2009.01.011

29 : PSYCHIAT RES

ISO : Psychiatry Res.

: 3

: Psychiatry

ISI : 533WD

2 413

: Yang, JC (Yang, Jianchang); Zhang, JH (Zhang, Jianhua)

: Grain-filling problem in 'super' rice

: JOURNAL OF EXPERIMENTAL BOTANY, 61 (1): 1-4 JAN 2010

: English

: Article

: Carbohydrate metabolism; grain-filling; inferior spikelets; soil drying; super rice

KeyWords Plus: ORYZA-SATIVA L.; DEVELOPING ENDOSPERM; CARBOHYDRATE STORAGE; YIELD; WHEAT; PANICLE; EXPRESSION; NITROGEN; CULTIVARS; SYNTHASE

: Modern rice (Oryza sativa L.) cultivars, especially the newly bred 'super' rice, have numerous spikelets on a panicle with a large yield capacity. However, these cultivars often fail to achieve their high yield potential due to poor grain-filling of later-flowering inferior spikelets (in contrast to the earlier-flowering superior spikelets). Conventional thinking to explain the poor grain-filling is the consequence of carbon limitation. Recent studies, however, have shown that carbohydrate supply should not be the major problem because they have adequate sucrose at their initial grain-filling stage. The low activities of key enzymes in carbon metabolism may contribute to the poor grain-filling. Proper field practices, such as moderate soil drying during mid- and late grain-filling stages, could solve some problems in poor grain-filling. Further studies are needed by molecular approaches to investigate the signal transport, the hormonal action, the gene expressions, and the biochemical processes in inferior spikelets.

: [Zhang, Jianhua] Hong Kong Baptist Univ, Dept Biol, Hong Kong, Hong Kong, Peoples R China; [Yang, Jianchang] Yangzhou Univ, Key Lab Crop Genet & Physiol Jiangsu Prov, Yangzhou, Jiangsu, Peoples R China

: Zhang, JH, Hong Kong Baptist Univ, Dept Biol, Hong Kong, Hong Kong, Peoples R China.

: jzhang@hkbu.edu.hk

:

National Basic Research Program

2009CB118603

National Natural Science Foundation of China

30771274

30871480

Doctoral Foundation of the Ministry of Education, China

200811170002

Research Grant Council of Hong Kong

HKBU 262809

Hong Kong University Grants Committee

AOE/B-07/99

Hong Kong Baptist University Strategic Development Fund

We are grateful for grants from the National Basic Research Program (973 Program, 2009CB118603), the National Natural Science Foundation of China (30771274, 30871480), the Doctoral Foundation of the Ministry of Education, China (200811170002), the Research Grant Council of Hong Kong (HKBU 262809), the Hong Kong University Grants Committee (AOE/B-07/99), and the Hong Kong Baptist University Strategic Development Fund.

: 28

: 0

: OXFORD UNIV PRESS

: GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND

ISSN: 0022-0957

DOI: 10.1093/jxb/erp348

29 : J EXP BOT

ISO : J. Exp. Bot.

: 4

: Plant Sciences

ISI : 531RU

3 413

: Su, YC (Su, Yuanchang); Hu, JG (Hu, Jingguo)

: New approach to spin dynamics simulation in magnetic system

: PHYSICS LETTERS A, 374 (2): 339-342 DEC 28 2009

: English

: Article

: Spin dynamics simulation; Landau-Lifshitz-Gilbert equation; Magnetic system; Computational time

KeyWords Plus: PARTICLES

: New approach to spin dynamics simulation in magnetic system is presented. In the approach, we substitute new algorithm for Landau-Lifshitz-Gilbert dynamics. which enable us to achieve the final stable state of magnetic system much faster than traditional spin dynamics simulation. A square-shaped sample with 32 x 32 x 4 size under different conditions is calculated. Our results show the new approach can largely reduce the computational time. (C) 2009 Elsevier B.V. All rights reserved.

: [Su, Yuanchang; Hu, Jingguo] Yangzhou Univ, Coll Phys Sci & Technol, Yangzhou 225002, Peoples R China

: Su, YC, Yangzhou Univ, Coll Phys Sci & Technol, Yangzhou 225002, Peoples R China.

: ycsu@yzu.edu.cn

:

National Natural Science Foundation of China

10974170

Natural Science Foundation of College of Jiangsu Province

09KJB140011

This work is supported by the National Natural Science Foundation of China under the grant No. 10974170 and the Natural Science Foundation of College of Jiangsu Province under the grant No. 09KJB140011.

: 17

: 0

: ELSEVIER SCIENCE BV

: PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS

ISSN: 0375-9601

DOI: 10.1016/j.physleta.2009.10.070

29 : PHYS LETT A

ISO : Phys. Lett. A

: 4

: Physics, Multidisciplinary

ISI : 529KP

4 413

: Zhang, QH (Zhang, Qinghua); Li, G (Li, Gang)

: On a class of second order differential inclusions driven by the scalar p-Laplacian

: NONLINEAR ANALYSIS-THEORY METHODS & APPLICATIONS, 72 (1): 151-163 JAN 1 2010

: English

: Article

: Sobolev space; Ordered Banach space; Upper and lower solutions; Upper semicontinuous map; Completely continuous operator; Fixed point; Maximal monotone map; Yosida approximation

KeyWords Plus: BOUNDARY-VALUE-PROBLEMS; PERIODIC-SOLUTIONS; SYSTEMS

: In this paper, we study a class of nonlinear value boundary problems for second order differential inclusions. By using the methods of upper-lower solutions, truncations and penalization, we give some existence results of the extremal (greatest and smallest) solutions. Our approach is based on the theories of fixed points, maximal monotone operators and ordered Banach spaces. (C) 2009 Elsevier Ltd. All rights reserved.

: [Zhang, Qinghua] Nantong Univ, Sch Sci, Nantong 226019, Peoples R China; [Zhang, Qinghua; Li, Gang] Yangzhou Univ, Sch Math Sci, Yangzhou 225002, Peoples R China

: Zhang, QH, Nantong Univ, Sch Sci, Nantong 226019, Peoples R China.

: zhangqh1971@126.com

: 19

: 0

: PERGAMON-ELSEVIER SCIENCE LTD

: THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND

ISSN: 0362-546X

DOI: 10.1016/j.na.2009.06.041

29 : NONLINEAR ANAL-THEOR METH APP

ISO : Nonlinear Anal.-Theory Methods Appl.

: 13

: Mathematics, Applied; Mathematics

ISI : 530FH

5 413

: Zhang, YM (Zhang, Yumei); Lu, H (Lu, Hao); Yuan, Y (Yuan, Yan); Liu, XZ (Liu, Xuezhong); Liu, ZP (Liu, Zongping)

: Neuroprotective effects of combined lead and cadmium, as well as N-acetylcysteine, on cerebral cortical neurons following lipid peroxidation injury

: NEURAL REGENERATION RESEARCH, 4 (11): 907-911 NOV 2009

: English

: Article

: lead; cadmium; cortical neurons; N-acetylcysteine; lipid peroxidation

KeyWords Plus: OXIDATIVE STRESS; RATS; EXPOSURE; BRAIN; ANTIOXIDANTS; INTOXICATION; INVOLVEMENT; DAMAGE

: BACKGROUND: Studies have reported the antioxidant effects of lead and cadmium in the central nervous system, but very few have addressed the combined toxicity of lead and cadmium. The mechanisms by which these combined heavy metals are toxic, as well as how to protect cells from these agents, remains poorly understood.OBJECTIVE: Primary cultured rat cortical neurons were used to determine the effects of combined lead and cadmium on levels of glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), catalase (CAT), and acetylcholinesterase (ACNE), as well as malondialdehyde (MDA), and to evaluate the neuroprotective effects of N-acetylcysteine (NAC).DESIGN, TIME AND SETTING: An in vitro toxicological observation was performed at the Comparative Medicine Center of Yangzhou University from August 2007 to April 2008.MATERIALS: Lead acetate, cadmium acetate, and NAC were purchased from Sigma-Aldrich (St. Louis, USA). Commercial kits of GSH-Px, SOD, CAT, ACNE, and MDA were purchased from Nanjing Jiancheng Bioengineering Institute, Nanjing, China.METHODS: The cerebral cortical neurons were isolated from newborn Sprague dawley rats at 24 hours after birth and primary cultured for 6 days. Thereafter, the cells were treated with a range of cadmium doses (0, 5.0, and 10.0 mu mol/L), lead doses (0, 1.0, and 2.0 mu mol/L), or a combination of the two for 12 hours at 37 degrees C in a 5% CO2 incubator, respectively. In addition, the cells were incubated with different doses of cadmium and/or lead and (0 and 50 mu mol/L) NAC for 12 hours to assess the protective effects on cell survival.MAIN OUTCOME MEASURES: The activity of SOD, GSH-Px, CAT, and ACNE, as well as MDA content, in the cell lysates was detected using commercial kits.RESULTS: At 12 hours after treatment, compared to the control group, activity of GSH-Px, SOD, and ACNE in the lead, cadmium, or combined treated cells was significantly decreased with increasing doses of cadmium/or lead (P < 0.05), but CAT activity and MDA levels were significantly increased (P < 0.05). The combination of cadmium and lead led to higher levels of toxicity than individual exposure.CONCLUSION: The degree of oxidative damage increased when the two heavy metals were combined. NAC protected neonatal cortical neurons by increasing activity of anti-oxidative enzymes, and reducing lipid peroxidation, but the reduction was not statistically significant.

: [Zhang, Yumei; Lu, Hao; Yuan, Yan; Liu, Xuezhong; Liu, Zongping] Yangzhou Univ, Coll Vet Med, Yangzhou 225009, Jiangsu Prov, Peoples R China; [Lu, Hao] NW A&F Univ, Coll Vet Med, Yangling 712100, Shaanxi Prov, Peoples R China

: Liu, ZP, Yangzhou Univ, Coll Vet Med, Yangzhou 225009, Jiangsu Prov, Peoples R China.

: liuzongping@yzu.edu.cn

:

National Natural Science Foundation of China

305713847

Natural Science Foundation of Jiangsu Province

BK2008214

Supported by: the National Natural Science Foundation of China, No. 305713847; Natural Science Foundation of Jiangsu Province, No. BK2008214

: 24

: 0

: SHENYANG EDITORIAL DEPT NEURAL REGENERATION RES

: PO BOX 1234, SHENYANG, LIAONING 110004, PEOPLES R CHINA

ISSN: 1673-5374

DOI: 10.3969/j.issn.1673-5374.2009.11.019

29 : NEURAL REGEN RES

ISO : Neural Regen. Res.

: 5

: Cell Biology; Neurosciences

ISI : 531KR

6 413

: Zhu, JW (Zhu, Junwu); Wang, JD (Wang, Jiandong); Li, B (Li, Bin)

: A formal method for integrating distributed ontologies and reducing the redundant relations

: KYBERNETES, 38 (10): 1870-1879 2009

: English

: Article

: Cybernetics; Integration; Programming and algorithm theory; Semantics

: Purpose - The purpose of this paper is to integrate distribut\ed ontologies on the web system and clarify the structure of the integrated oneDesign/methodology/approach - A formal method based on concept lattices is introduced as a mechanism to form more general semantic level. By checking the extension and the intension of concept, this method extracts the concept pairs satisfying inclusion relations from descartes' set of concepts in distributed ontologies first, and then constructs a concept lattice according to these concept pairs An algorithm to reduce redundant relations is also proposed to clarify the structure of integrated ontology.Findings - The experiments demonstrate the effectiveness of the proposed method to reduce redundant relations, and the Nir-to-Ner ratio inclines to 1 05 from 3 13.Research limitations/implications - Instances of certain concept are not given completely on the web, so it is difficult to check extension of different conceptsPractical implications - A very useful method of integrating distributed ontologies on the webOriginality/value Compared with existing methods, this formal method can be performed by program automatically without any human intervening, and can extract the inclusion relations between concepts from distributed ontologies completely.

: [Zhu, Junwu; Wang, Jiandong] Nanjing Univ Aeronaut & Astronaut, Coll Informat Sci & Technol, Nanjing 210016, Peoples R China; [Zhu, Junwu; Li, Bin] Yangzhou Univ, Coll Informat Engn, Yangzhou, Peoples R China; [Li, Bin] Nanjing Univ, State Key Lab Novel Software Technol, Nanjing 210008, Peoples R China

: Zhu, JW, Nanjing Univ Aeronaut & Astronaut, Coll Informat Sci & Technol, Nanjing 210016, Peoples R China.

:

National 863 Project

2006AA12A106

JSNSF

BK2007074

JSENSF

06KJB520132

This paper is jointly supported by National 863 Project (2006AA12A106), JSNSF with the Project No. BK2007074 and JSENSF with the Project No. 06KJB520132.

: 17

: 0

: EMERALD GROUP PUBLISHING LIMITED

: HOWARD HOUSE, WAGON LANE, BINGLEY BD16 1WA, W YORKSHIRE, ENGLAND

ISSN: 0368-492X

DOI: 10.1108/03684920910994411

29 : KYBERNETES

ISO : Kybernetes

: 10

: Computer Science, Cybernetics

ISI : 531SC

7 413

: Xi, JQ (Xi, Juqun); Guo, R (Guo, Rong)

: Studies on the Interactions Between Genistein and Copolymer F127

: JOURNAL OF SOLUTION CHEMISTRY, 38 (12): 1588-1600 DEC 2009

: English

: Article

: Polymeric micelles; Genistein; Complex; pH dependence; Controlled release

KeyWords Plus: PLURONIC((R)) BLOCK-COPOLYMERS; POLYMERIC MICELLES; TRIBLOCK COPOLYMERS; DRUG CARRIERS; DELIVERY; CANCER; SOLUBILIZATION; COMPATIBILITY; MOLECULES; RELEASE

: In this paper, the interactions of an isoflavone molecule, Genistein (Gen), with Pluronic F127 at different pH values have been investigated using laser light scattering techniques, film analysis methods, UV-vis spectroscopy and transmission electron microscopy. The TEM images and the DSL studies indicate the formation of a Gen/F127 complex induced by the solubilization of Gen in micelles, and the stability of the Gen/F127 complex decreases with the increase of pH. At pH of 6.4, the turbidity of the Gen/F127 complex solution is significantly reduced in the presence of 0.31 mola