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Education

Ph.D–2013DepartmentofGenetics,UniversityofDelhiSouthCampus,NewDelhi,India.

M.Phil–2008DepartmentofZoology,UniversityofDelhi,Delhi,India.

M.Sc-2007DepartmentofZoology,UniversityofDelhi,Delhi,India.

B.Sc-2005SeramporeCollege,UniversityofCalcutta,Kolkata,India.Experience

1. Assistant Professor (Aug 2015 – till date): Department of Human Genetics and Molecular Medicine, Central

UniversityofPunjab,Bathinda,India

Nature of Work: Teaching & mentoring M.Sc and Ph.D students and Research; social and administrative

responsibilities

2. AssistantProfessor(Feb2014–Aug2015):DepartmentofZoology,RamjasCollege,UniversityofDelhi,Delhi,India

NatureofWork:TeachingUnder-graduatestudents

3. VisitingPhDFellow(Mar2011–Sept2011):DepartmentofHumanGenetics,UniversityMedicalCentreGroningen,

UniversityofGroningen,Groningen,TheNetherlands

Nature of Work: Worked with Prof.Cisca Wijmenga’s research group as a visiting PhD fellow. Participated in

InternationalconsortiumforCeliacdiseaseasateammemberfromProf.ThelmaB.K’sGroupatUniversityofDelhi

SouthCampus,NewDelhi,India TeachingAssignments

Presentlyteaching:M.ScHumanGenetics;andM.ScLifeSciences,PhDHumanGenetics,andMolecularMedicine.

MasterofScience:

Semester-I:Biostatistics&ResearchMethodology(LHG.506),ConceptsofGenetics(LHG.512).

Semester-II: Human Embryology & Developmental Genetics (LHG.525), Population Genetics & Genetic Epidemiology

(LHG.526).

Semester-III:BioinformaticsandComputationalBiology(LHG.550),Pharmacogenomics&Nutrigenomics(LHG.553).

Semester-IV:RecombinantDNAtechnologyandTherapeutics(LHG.571).

Ph.DCoursework:ResearchmethodologyandBiostatistics(LHG.701).

SupervisedasMentorM.Sc.=23

PhD:02(ongoing)

ProjectJRF:01

UGCJRF:01

DSTWomenScientist(WOS-A)Fellow:01

ProfessionalRecognition/Awards/Scholarship

SabyasachiSenapatiPhD AssistantProfessor HumanGeneticsandMolecularMedicineSchoolofHealthSciences CentralUniversityofPunjab Bathinda-151001 Emailid:sabyasachi1012@gmail.com,s.senapati@cup.edu.in Phone:+91-164-2864-187(Office);+91-9953643083(Mobile)

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• YoungScientistTravelAward,InternationalCongressofHumanGenetics,April.2016,Kyoto,Japan.• YoungScientistAward,AssociationofBiotechnology&Pharmacy,Oct.2013,NewDelhi,India.• Visitinggraduatestudentfellowship(Mar2011–Sept2011)byUniversityMedicalCentreGroningen,Groningen,The

Netherlands.• CSIRJuniorresearchfellowship(2007,2008)• QualifiedforprestigiousDr.ShyamaPrasadMukherjee(SPM)Fellowship-CSIR,Dec.2007andJune2008

Areaspecializations/ResearchInterestSpecificareasofinterestare:

• Complexdiseasegenetics(Celiacdisease,COPD,Granulomatosiswithpolyangiitis)

• Systemsbiology

• Populationgenomics

Ourresearchgroupaimingtocontributefor improvingpublichealthglobally.Currentlyweare interested inworkingwith

high-throughput“Omics”datato investigatethecauseforonsetof immunemediateddiseases, theirearlypredictionand

identifyprobabledrugtargetsfortheirtreatment.Weareutilizingseveralbiostatistical,bioinformaticsandcomputational

toolstosolvethepuzzleofimmunerelateddiseases.Anotherpartofourresearchisfocusedontrans-ethniccomparisonof

genome-widedatatounderstandevolutionaryaspectofhumandiseases.

Laboratory is presently working on in silico analyses of clinical and epidemiological data, using bioinformatics and

biostatisticaltoolstoaddressmajorpublichealthcrisis,invitrovalidationofidentifieddiseaseassociatedgenes.

Publications

A.ResearchPapers1. Sharma,N.Singh,K.Senapati, S.Celiacdiseaseposes significant risk indevelopingneuropsychiatricdiseases:Ameta-

analysis.Submitted.2. Bhagavatula, S. Banerjee, P. Sood, A. Midha, V. Thelma, BK. Senapati, S. Energy metabolism genes with synergistic

functionsidentifiedinceliacdisease.Submitted.3. Bhattacharya, N.Maurya, SK. Senapati, S. Bhattacharya, A. Drug repurposing: A strategy to treat human coronavirus

disease(COVID-19).Submitted.4. Sharma,N.Bham,K.Senapati,S.HumanAnkyrinsandtheircontributionindiseasebiology:ARecentUpdate.Journalof

Biosciences.2020.(InPress).(IF:1.65)5. Senapati, S. Banerjee, P. Bhagavatula, S. Kushwaha, PP. Kumar, S. Contributions of human ACE2 and TMPRSS2 in

determininghost-pathogeninteractioninCOVID-19.JournalofGenetics.2020.(InPress).(IF:0.99)6. Senapati, S. Kumar, S. Singh, AK. Banerjee, P. Bhagavatula, S. Assessment of risk conferred by coding and regulatory

variantsofTMPRSS2andCD26insusceptibilityofSARS-CoV-2infectioninhuman.JournalofGenetics.2020.99(1):53.(IF:0.99)

7. Gupta, S. Singh, AK. Kushwaha, PP. Prajapati, KS. Shuaib,M. Senapati, S. Kumar S. Identification of potential naturalinhibitors of SARS-CoV2 main protease by molecular docking and simulation studies. Journal of Biomolecular &StructuralDynamics.2020.11:1-12.(IF:3.31)

8. Banerjee,P.Bhagavatula,S.Sood,A.Midha,V.Thelma,BK.Senapati,S.Associationstudyidentifiedbiologicallyrelevantreceptorgeneswithsynergisticfunctionsinceliacdisease.ScientificReports.2019.9(1):13811.doi:10.1038/s41598-019-50120-4.(IF:4.53)

9. Khanna,R.Nandy,D.Senapati,S.Sysematic reviewandmeta-analysis toestablish theassociationofcommongeneticvariationsinvitaminDbindingproteinwithchronicobstructivepulmonarydisease.FrontiersinGenetics.2019.10:413.doi:10.3389/fgene.2019.00413.(IF:4.15)

10. Nandy,D. Sharma,N. Senapati, S. Systematic reviewandmeta-analysis confirms significant contributionof surfactantproteinDinchronicobstructivepulmonarydisease.FrontiersinGenetics.2019.10:339.doi:10.3389/fgene.2019.00339.(IF:4.15)

11. Chaudhary,D.Sharma,N.Senapati,S.Serumhomocysteinecouldbeusedasapredictivemarkerforchronicobstructivepulmonarydisease:AMeta-analysis.FrontiersinPublicHealth.2019.7:69.doi:10.3389/fpubh.2019.0069.(IF:2.03)

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12. Marquez, A. Kerick, M. Coeliac Disease Immunochip Consortium. et al. Meta-analysis of Immunochip data of fourautoimmune diseases releals novel single-disease and cross-phenotype associations.GenomeMed.2018.20;10(1):97.doi:10:1186/s13073-018-0604-8.(IF:8.90)

13. Senapati, S. Sood, A. Midha, V. Sood N. Sharma, S. Kumar, L. Thelma B.K. Shared and unique genetic determinantsbetweenpediatricandadultceliacdisease.BMCMedicalGenomics,2016,9(1):44.(IF:3.32)

14. Senapati,S.Bharti,N.Bhattacharya,A.Modernlifestylediseases:chronicdiseases,awarenessandprevention.IntJCurrResAcadRev.2015;3(3),215-3.(IF:--)

15. Senapati, S. Gutierrez-Achury, J. Sood, A. Midha, V. Szperl, A. Romanos, J. Zhernakova, A. Franke, L. Thelma, B.K.Wijmenga, C. Trynka, G. Evaluation of European coeliac disease risk variants in a North Indian population. EuropeanJournalofHumanGenetics,2015;23(4):530-5.(IF:4.35)

16. Juyal,G.Negi,S.Sood,A.Senapati,S.Gupta,A.Prasad,P.Singh,S.Zaneveld,J.Midha,V.vanSommeren,S.Weersma,R.K.Ott,J.Jain,S.Juyal,R.C.Thelma,B.K.Genome-wideassociationscaninanorthIndiancohortidentifiesthreenovelHLAindependentsusceptibilitylociinulcerativecolitis.Gut,2015;64(4):571-9.(IF:17.02)

17. Senapati, S. Singh,S.Das,M.Kumar,A.Gupta,R.Kumar,U. Jain, S. Juyal,R.C.Thelma,B.K.Genome-wideanalysisofmethotrexate pharmacogenomics in rheumatoid arthritis reveals novel risk variants and leads for TYMS regulation.PharmacogeneticsandGenomics,2014:24(4):211-9.(IF:2.25)

18. Negi,S.Juyal,G.Senapati,S.Prasad,P.Gupta,A.Singh,S.Kashyap,S.Kumar,A.Kumar,U.Gupta,R.Kaur,S.Agrawal,S.Aggrawal,A.Ott, J. Jain, S. Juyal, R.C. Thelma,B.K.A genome-wideassociation study revealsARL15, a novel non-HLAsusceptibilitygeneforRheumatoidarthritisinnorthIndians.Arthritis&Rheumatology,2013;65(12):3026-35.(IF:6.92)

19. Trynka,G.Hunt,K.A.Bockett,N.A.Romanos,J.Mistry,V.Szperl,A.Bakker,S.F.Bardella,M.T.Bhaw-Rosun,L.Castillejo,G.delaConcha,E.G.deAlmeida,R.C.Dias,K.R.vanDiemen,C.C.Dubois,P.C.Duerr,R.H.Edkins,S.Franke,L.Fransen,K.Gutierrez, J.Heap,G.A.Hardlickova,B.Hunt,S.Plaza Izurieta,L. Izzo,V. Joosten,L.A.Langford,C.Mazzilli,M.C.Mein,C.A.Midha, V.Mitrovic,M.Mora, B.Morelli,M. Nutland, S. Nunez, C. Onengut-Gumuscu, S. Pearce, K. Platteel,M.Polanco,I.Potter,S.Ribes-Koninckx,C.Ricano-Ponce,I.Rich,S.S.Rybak,A.Santiago,J.L.Senapati,S.Sood,A.Szajewska,H. Troncone, R. Varadé, J.Wallace, C.Wolters, V.M. Zhernakova, A. Spanish Consortium on the Genetics of CoeliacDisease(CEGEC).PreventCDStudyGroup.WellcomeTrustCaseControlConsortium(WTCCC).Thelma,B.K.Cukrowska,B.Urcelay,E.Bilbao,J.R.Mearin,M.L.Barisani,D.Barrett,J.C.Plagnol,V.Deloukas,P.Wijmenga,C.vanHeel,D.A.Densegenotyping identifies and localizes multiple common and rare variant association signal in celiac diseases. NatureGenetics,2011;6;43(12):1193-201.(IF:27.13)

20. Garima,J.Prasad,P.Senapati,S.Midha,V.Sood,A.Amre,D.Juyal,R.C.Thelma,B.K.Aninvestigationofgenome-widestudiesreportedsusceptibilitylociforulcerativecolitisshowslimitedreplicationinnorthIndians.PLoSONE,2011;6(1):e16565.(IF:2.77)

Viewmypublicationsat:

GoogleScholarCitation:https://scholar.google.co.in/citations?hl=en&user=_QX2EpsAAAAJ

ResearchGate:https://www.researchgate.net/profile/Sabyasachi_Senapati

Linkedin:https://www.linkedin.com/in/sabyasachi-senapati-18a89a39/

B.PopularArticles

1. Personalizedmedicine:Ahopeforbetterpublichealth.October.2015.NEScholarMagazine

2. VaccineDevelopment:Trials,ApprovalProcessandEthicalIssues.2020,October.Dream2047.VigyanPrasar.

C.Books/BookChapter

1. Bhattacharya,A.Sharma,N.Bhattacharya,N.Senapati,S.Insilicotargetsinimmuneresponse.Springer,Singapore.

2019.pp393-402.doi:10.1007/978-981-13-6920-9_21.eISBN:978-981-13-6920-9.

2. Sharma,N.Dhekne,HS.Senapati,S.Immunomodulatorypotentialofphytochemicals:Recentupdates.Springer,

Singapore.2019.pp133-160.doi:10.1007/978-981-13-6920-9_8.eISBN:978-981-13-6920-9.

3. Senapati,S.AlternativePathwaysforGlucoseMetabolism.NovaSciencePublishers.USA.2017.ISBN.978-1-53612-

907-6.

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Workshop/ConferencesA.Attended/Presented

OrientationandRefresherCourses

1. TwoWeekOnlineFacultyDevelopmentProgrammeon“ManagingOnlineClassesandCo-CreatingMOOCS3.0”.July25–August10,2020.PMMMNMTTTeachinLearningCentre,RamanujanCollege,UniversityofDelhi,NewDelhi,India.

2. ScienceAcademies’RefresherCourseon“PlantTaxonomy,PhytogeographyandEcology”.March05–March20,2019.CentralUniversityofPunjab,Bathinda,Punjab,India.

3. UGC-Sponsored “Orientation Programme”. November 13 – December 10, 2018. UGC-HRDC, Punjab University,Chandigarh,India.

Workshops/Trainings:

1. Genetic Epidemiological Research and Data Analysis. May 23-27, 2011. By Graduate School for Drug Exploration.UniversityMedicalCenterGroningen,TheNetherlands.

2. International course on EpidemiologicalMethods. Organized by International Epidemiological Association. April 5-7,2009.Jaipur,India.

3. GeneticEpidemiologicalMethodsforDissectionofComplexHumanTraits.OrganizedbyTCG-ISICentreforpopulationgenetics,KolkataandUniversityofPittsburgh,Pittsburgh,U.S.A.Feb.23-28,2009.Kolkata,India.

ConferencesandSymposiums:

1. International Webinar on “Prospects of Natural Products on Human Health in Current Scenario”. June 24, 2020.DepartmentofBotany,BanarasHinduUniversity,Varanasi,India.

2. “InternationalCOVID-19Conference”.May15,2020.StanfordCenterforContinuingMedicalEducation,Stanford,CA,USA.

3. 44thAnnualConferenceof the IndianSocietyofHumanGeneticson“Genomics forHealthandPrecisionMedicine”.Jan.30th-Feb.1st2019.NIBMG&UniversityofKalyani,WestBengal.India.

4. 1stNationalBiomedicalResearchCompetition.October15.2018.AIIMS,Rishikesh,India.5. RecentAdvances inMlecularGeneticsWithNewBiomedical Insights.An Indi-IsraelMeeting.February 12-13. 2018.

IndianNationalScienceAcademy(INSA),NewDelhi,India.6. 17thInternationalCeliacDiseaseSymposium.Sept.8-10.2017.LeMeridean,NewDelhi,India.7. 42ndAnnualMeetingoftheIndianSocietyofHumangenetics&InternationalSymposiumonTrendsinHumanGenetic

Research&Management.March2-4.2017.IndianInstituteofScience,Bengaluru,India.8. The 13th International Congress of Human Genetics. April 3-7, 2016. Kyoto International Conference Center, Kyoto,

Japan.9. 7th Annual Convention of Association of Biotechnology and Pharmacy&International Conference on Plant

Biotechnology,MolecularMedicine & Human Health. October 18-20, 2013. University of Delhi South Campus. NewDelhi.India

10. NationalScienceDaySymposium-2013.February27-28,2013.UniversityofDelhiSouthCampus,NewDelhi.

11. InternationalconferenceonGenes,GeneticsandGenomics:TodayandTomorrow-HumanconcernsandXXXVIIannualconferenceofTheIndianSocietyofHumanGenetics.March3-5,2012.PanjabUniversity,Chandigarh,India.

12. NationalScienceDaySymposium-2012.February27-28,2012.UniversityofDelhiSouthCampus,NewDelhi.

13. 12th International Congress of Human Genetics & 61st American Society of Human Genetics.October 11-15, 2011.Montreal,Canada.

14. InternationalNetworkingConference: FromDNA toPhenotype.March9–11,2011.ErasmusMC,UniversityMedicalCenterRotterdam,Rotterdam,TheNetherlands.

15. International conference onMolecular and Clinical aspects ofGonadal andNon-gonadal actions ofGonadotropins.February7-9,2008.NewDelhi.India.OrganizedbyDepartmentofReproductiveBiology,AllIndianInstituteofMedical

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Sciences,NewDelhi,India

16. 30th All Indian Cell Biology Conference & Symposium on Molecules to Compartments: Cross-Talk and Networks.February2-4,2007.NewDelhi.India.OrganizedbyDepartmentofZoology,UniversityofDelhiandIndianSocietyofCellBiology.

Meetings:

1. 6th National IBDMeet on IBD. September 15-16, 2018. Convention Centre, Hotel Pullman, NewDelhi. Organized byColitisandCrohn’sFoundation(India).

2. 3rdNational IBDMeet on IBD in different ethnic groups: East vs.West? September 29-30, 2012.Gurgaon,Haryana,India.OrganizedbyColitisandCrohn’sFoundation(India).

3. 2ndNational IBDMeet onUnderstanding the enigmaof IBD in India.May23, 2010.NewDelhi, India.OrganizedbyColitisandCrohn’sFoundation(India).

4. SatellitemeetingofHGM2008onClinicalGenomics.September25,2008.NewDelhi,India.OrganizedbyIndianCouncilforMedicalresearch

B. Organized

Workshops/Trainings:

1. Organizing Member. “Indian Traditional Medicine in Cancer Therapy and Prevention”. February 4th, 2020. CentralUniversityofPunjab,Bathinda.

2. OrganizingMember.“ExpertLecturesonCancerPreventionandAwareness”.February3rd,2020.CentralUniversityofPunjab,Bathinda.

3. OrganizingSecretary.Speciallectureson“GenomicMedicine”&Workshopon“MolecularModelling&DevelopmentalGenetics”.March24-25,2017.CentralUniversityofPunjab,Bathinda,Punjab.

4. Organizing Member. DBT-Sponsored Training Course in Medical Genetics and Bioinformatics. March 9-23, 2016.CentralUniversityofPunjab,Bathinda,India.

5. Organizing Secretary. Workshop on Model Organisms in Molecular Genetic Research. March 21, 2016. CentralUniversityofPunjab,Bathinda,Punjab.

InvitedLecturesandTalks1. Invited talk atNationalSymposiumon“RecentTrendsandEthics inBiologicalResearch”March7,2020.Dyal Singh

College,UniversityofDelhi,NewDelhi2. Invitedtalkat2ndNationalSeminaron“ResponsibleResearchandInnovationsinScience&Technology”(RRIST-2020),

February29,2020.GuruNanakCollege,PunjabiUniversity,Budhlada3. Talk on “Genome-wide association study identified several novel genes and BMP associated pathways with bone

erosioninrheumatoidarthritis”at44thAnnuamConferenceofIndianSocietyofHumanGenetics.Jan31st-1stfeb,2019.KalyaniUniversity,WestBengal.India

4. Lectureon“StrategiesforLinkageandAssociationmapping”,atDBT-SponsoredTrainingCourseinMedicalGeneticsandBioinformatics.March9-23,2016.CentralUniversityofPunjab,Bathinda,India

5. Lectureon“IntroductiontoBiostatistics”,atDBT-SponsoredTrainingCourseinMedicalGeneticsandBioinformatics.March9-23,2016.CentralUniversityofPunjab,Bathinda,India

LaboratoryProjects

Sr.No. OngoingProjects FundedBy&Duration Tenure

1. In silico evaluation of non-coding genome involved inImmune-mediateddiseases(PI)

CentralUniversityofPunjab(ResearchSeedMoney)

(2016-18)

2. Identificationofnon-codingRNAinceliacdisease(PI)

UniversityGrantCommission(BRS)

(2017-19)

3. Investigation of non-coding genome mediated geneexpressionregulationinceliacdisease(PI)

Science&EngineeringResearchBoard(DST)(EarlyCareerResearchGrant)

(2017-20)

4. FunctionalgenomicsofANK3implicatedinceliacdisease DSTWomenScientist-A researchgrant (toMs.Nidhi (2019-21)

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(Mentor) Sharma)

5. Clinical and Molecular Characterization of PrimordialDwarfism(Pd)inIndianPatients(Co-PI)

ICMR(TaskForceforRareDisorders)(2019-2022)

6. An Indian Initiative To Study Granulomatosis WithPolyangiitisThroughClinicalAndGenomicsApproach(PI)

ICMR(TaskForceforRareDisorders)(2019-2022)

AcademicandAdministrativeAssignments1. Member,AcademicandAdministrativeCommittee(AAC),DepartmentofHumanGenetics&MolecularMedicine,CentralUniversityof

Punjab.

2. Member,CurriculumDevelopmentCommittee(CDC),DepartmentofHumanGenetics&MolecularMedicine,CentralUniversityof

Punjab.

3. Member,BoardofStudies(BOS),DepartmentofHumanGenetics&MolecularMedicine,CentralUniversityofPunjab.

4. Member,SchoolBoard,SchoolofHealthSciences,CentralUniversityofPunjab.

5. Member,InstitutionalEthicsCommittee(IEC),CentralUniversityofPunjab.

6. ProgramOfficer,NSS,CentralUniversityofPunjab.

ProfessionalMembership1. LifeMemberofIndianSocietyofHumanGenetics(ISHG),Hyderabad,India.

2. LifeMemberofIndianSocietyofCellBiology(ISCB),Varanasi,India.

3. LifeMemberofInternationalSocietyforStudyofCeliacDisease(ISSCD),Hague,Netherlands.

Collaboration1. Professor.ThelmaB.K,DepartmentofGenetics,UniversityofDelhiSouthCampus,NewDelhi,India

2. Professor.UmaKumar,Head,DepartmentofRheumatology,AIIMS,NewDelhi,India

3. Professor.AjitSoodandDr.VandanaMidha,DepartmentofGastroenterology,DayanandMedicalCollegeand

Hospital,Ludhiana,Punjab,India.

4. Dr.VitullK.Gupta,DepartmentofMedicine.AdeshInstituteofMedicalSciencesandResearch,Bathinda,Punjab.

India.

5. Dr.ChetanaSachidanandan.CSIR-InstituteofGenomicsandIntegrativeBiology.NewDelhi,India.

6. MemberofCoeliacDiseaseImmunochipConsortium,TheNetherlands.

Date:02/9/2020.

Banerjeeetal.2019,Scien

ResearchHighlights

Senapatietal.,2020,JournalofGenetics

Sharmaetal.2020,JournalofBiosciences

Senapatietal.,2020,JournalofGenetics

Senapatietal.,2016,BMCMedicalGenomics

Khannaetal.,2019,FrontiersinGenetics

Banerjeeetal.,2019,ScientificReports