מחלות ממאירות-פורמולות.ppt
TRANSCRIPT
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, (Cl.H), N.D , RH(AHG).. Email:[email protected]
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Antioxidant . (ROS) .
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-:Camellia sinensisSchizandra chinensis/Wu wei ziGanoderma lucidumCurcuma longa
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Antitumour . . . .
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:Larrea mexicanaPhytolacca decandraThuja occidentalisScutellaria barbata
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Anti-inflammatory - . : ; ; ; . ; COX - LOX; ; ; .
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- , , . .
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() Alterative . , -. : , .
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, , . .
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- AlterativesTabebuia impetiginosaArctium lappa
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Lymphatic . . (-) .
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:Galium aparineIris versicolor
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()1. : . , , .
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2. - : , , -/ " .
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3. /: . "", , (,), , .
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1. - : , , , :
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Astragalus membranaseus (1995) 115 ( ). . ' - 15 , , ' - 5 . 82.76% ' 47.37% '. .1
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(2005) ( ) . 72 , . sFas, sFasL, TNF-? - IL-6 - .
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( , ). , . , , , , .4
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(2006) - (). 34 : - 12 (" 940 ) 12 ; - 30 (2472 ) . .5
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Andrographis paniculatae (2007) Andrographolide . T , IL-2 -IFN- T .7,8
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(2007) , Neoandrographolide, -. : NO - TNF-alfa " .9 iNOS -COX-2 , p38 10MAPK.
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Withania somnifera 1980 -58 8-12 60 . . . .1
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3 101 50-59 . , . (ESR). 71 .2
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1985 . 100 mg\kg 8 . .3
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1987 (Cyclophosphamide) .4
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: 1967, 1970, 1976 .Withaferin A Carcinoma Human nasopharyngeal. - ascites Carcinoma cell Erlich.8-12
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(2004) , ( ).5
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Rhodiola rosea - 40 . , -. , . , , , , , .1
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Eleutherococcus senticosus .(5) - 1987 Natural killer cells - T-helper cells .(6)
:Panax Ginseng,Atractylodes.
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2. - :
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Tabebuia impeteginosa - -60 . , .
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Lapachol - , -, . Lapachol DNA , DNA . , .1
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cell line HCT-116 - () -, , -. - NF-kappaB NF-kappaB-DNA . , - NF-kappaB.2
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- Lapachol - , - . 1970 - - Chase Pfizer & Co. inc, Lapachol , "" , "-" .
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" Lapachol , . , , 4.Lapachol
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Arctium lappa (4 ), (0.5 "/ ). , , P-450, NADPH, , . .5
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. 30 SOD ( ), . -MDA -Lipofuscin ( ) . , " ".6
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, ( ), Arctigenin, , .7
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: , ( ). (apoptosis). - Matairesinol, Arctigenin, Didehydroarctigenin , Arctigenin .8
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, Arctigenin . . , (). .9
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. , . (Lignans). (2006) ,Larrea divaricata 0.040.1 mg/l (Helicobacter pylori) clarithromycin - metronidazole.1
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(2006) (Methanolic) L. divaricata - . - . - .2
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(2005) Larrea tridentate . .4
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(2007) NDGA E6 (VPH) . E6 p53 ( ) . E6 p53 .7
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Phytolacca spp.
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Anemarrhena asphodeloides (2007) , , Sarsasapogenin. .
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Scutellaria barbata-Ban zi lian
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Ganoderma lucidum , . " (1999) Mao, T. el al : , , - .
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(1999) Wang, S.Y. et al ' T." (2003) Gao, Y. et al , 1800 " 3 12 . (IL-2) Natural killer.1
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(2004) 720 " 10 .4
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Curcuma longa-Turmeric
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: (OA), (IBD), ( ).
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. , (Curcumin). , 97% . , - . , Lipoxygenase 5 - Cyclooxygenase.
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, .2 (RA) 120 " .3 20 " -18 , 45 . (Lipid peroxide) .4
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- . , : ; - ( ) ; (PKC), .5
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, 6; - - , .7
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Schisandra chinensis-Wu wei zi
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-1996, AFLATOXIN B1 . E . .1
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SCISANDRIN B (CC14) CARBON TERACHLORIDE. -SCISANDRIN B . . .2
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(THA) TACRINE - SCISANDRIN B . TACRINE , .3
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Camellia sinensis-Green tea . , , , , , . 6 , -1.5 .
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. , . . , , . ". , . -16 , -17 . , .
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. , , - . , . .
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( ). : - : benzoic acid, carvacrol, chlorogenic acid, gallic acid, cinnamic acid, salicylic acid, thymol - (3.4-27%): epicatechin, epigallocatechin, epicatechin 3 gallate, epigallocatechin 3 gallate, catechin, gallocatechin, theogallin, trigalloyl glucose, epiafzelichin, tannic acid, thearubigin, theaflavin
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: quercetin, quercitrin, kaempferol, apigenin, hyperoside, rutin, vitexin, astragalin, luteolin : procyanidin-B -2, prodelphinidin-A-2-3'-o-gallate : - : linalool, nerol, neral, citronellol, geraniol, gernial, citral, myrcene, ocimene - : , farnesol, 4-terpineolbeta-sesquiphellandrene - : , , - : -, , , ,
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: (9-27%), (6.5%), (0.5%) : - caffeine (1-5%), theophylline, theobromine, theanine : : : C, B1, B2, B3, B5, ( (E, K : , , , , , , , , , , .
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-, \ , , , , , , , . : ( ), ( ). : , , (), ().
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-2003 \ . (1-6 ). , DNA . , .1
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. () 18,244 45-64, 12 . 190 -42 . 772 -.2
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2001 .3,4 , .5
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13,916 40-69 86.7% . , - HDL .6 .7 .8
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1. :PLM4DE Astragalus 150 mgDE Andrographis 100 mgDE Lonicera 50 mgDE Zingiber 50 mg: 0-3 , 3 2-5 Caps X 3-4
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ONC2DE Ganoderma 100 mgDE Grifola (maitake) 100 mgDE Cordyceps 100 mgDE Glycyrrhiza(DGL) 20 mgDE Zingiber 30 mg: 1-3 , 3 ONC3DE Ganoderma lucidum 350 mg: 1-3 , 1-3
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YU PING FENG SANHuang Qi - Astragalus membranaceus Fang Feng - Ledebouriella seseloides Bai Zhu - Atractylodes macrocephala
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MUSHRUMS " "
Ganoderma-25%Cordyceps-15%Poriacoccus(Fu ling)-30%Polyporus(Zhu ling)-25%Zingiber-5%5-10cc *2
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GAN RAN(SFF)
Ban lan genJin yin huaDa qing yeChuan xin lianBo heChai huSheng jiang
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( ):
BU ZHONG YI QI TANG+BA ZHEN TANG
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( ) Althaea r.1 X 3
Laxy syrup
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FH10Pulv.Elettaria 150 mgDE Zingiber 100 mgDE Glycyrrhiza (DGL) 100 mg: 0-5 ,
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2. :
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- 1Cytotoximix Tinc. Larrea/Iris - 25%Tinc. Tabebuia - 30%Tinc.Scutellaria barbata-30%Tinc. Zingiber- 5%Ext.Glycyrrhiza-10%5-10cc X 4-5
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2
-/ : ONC4FE scutellaria barbata 90%FE zingiber officinale 10% " 1:1 . : 5-10 " , .
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2.ONC5FE Anemarrhena rhizome 80%FE Zingiber officinale 10%FE Atractylodes rhizome 10% " 1:1 . : 5-10 " , .
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. . , , . () ().
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:1. / .2. , .3. .
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, ( ), , ' ( ) -.
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: Galium-
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, ' :PLM4ONC2/ONC3YU PING FENG SAN
' , ( ) 1:2 1:1
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3. : ONC2DE Ganoderma 100 mgDE Grifola (maitake) 100 mgDE Cordyceps 100 mgDE Glycyrrhiza(DGL) 20 mgDE Zingiber 30 mg: 1-3 , 3
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ONC3DE Ganoderma lucidum 350 mg
: 1-3 , 1-3
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MUSHRUMS " "
Ganoderma-25%Cordyceps-15%Poriacoccus(Fu ling)-30%Polyporus(Zhu ling)-25%Zingiber-5%5-10cc *2
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MTB7Comp.Curcuma longa mix (1:1): 5-10 ", 1-3 MTB8 ( )Comp. Curcuma longa caps (95%) - 1000 mg: 1-3 , . ONC1DE Camellia Sinensis(95%) 350 mg: 1-3 , 3
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Comp.Curcuma longa(1:1) Liq-Ext.Curcuma longa(1:1)-95% Liq-Ext.Piper nigrum(1:1)-5%
5-10cc*2
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:
1 .