matlab.iis.u-tokyo.ac.jp overview 3d microvessel model
TRANSCRIPT
Center for International Research on Integrative Biomedical Systems
http: / /mat lab. i is .u-tokyo.ac. jp
An-512
DISEASE
Overview
HEALTHY
Bundled gel as cell scaffold
Y.J. Kim and Y. Takahashi et al., J. Mater. Chem. B, 3, 8154-8161 (2015), Y.J. Kim et al., Biomater. Sci., 4, 1197-1201 (2016).
2.5 mm
200 μm
Colormap imageROI
microvessel
PDMS channel
Fluorescence image
PDMS channel
Bars= 100 µm
OCT image 3D image by OCT
Fluorescence image
leakage
FITC-dextran
Inflammatory factor
Barrier-strengthening compound
Endothelial Barrier
Function Assay
3D microvessel model
Vascular permeability assay
3D imaging of angiogenesis
J. Pauty, R. Usuba et al., Nanotheranostics, 1, 103-113 (2017).
H. Takahashi et al., Sci. Rep., 7, 42426 (2017).