微觀之開放資料 geo
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in course of Health and Bioinformatics
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dna micro array animation.mp4 Microarray Printer.mp4
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基因表現頻譜分析:數万個變項 *千百計的樣本台灣生物資料庫: 64萬以上變項 *23萬計個案
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April 28, 2014 國醫公衛所 6
Y axial presents cluster of 55 genes
X axial presents 1274 samples with normal via blue, adenoma via green, carcinoma and adenocarcinoma via purple and metastasis via black
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April 28, 2014 國醫公衛所 7
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April 28, 2014 國醫公衛所 8
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Gene symbol Model1﹟
(n=1,274)
Model2﹠
(n=759)
Model3||
(n=1,274)
Model4﹢
(n=272)
Model5﹪
(n=722)
Model6@
(n=185)
OR p OR p OR p OR p OR p OR p
AQP8 0.57 *** 0.27 *** 0.58 *** 0.62 *** 0.27 *** 0.17 0.06
CA7 0.29 *** 0.30 *** 0.29 *** 0.38 *** 0.34 *** 0.46 **
CWH43 0.21 *** 0.04 *** 0.20 *** 0.13 *** 0.04 *** 0.07 *
GUCA2B 0.47 *** 0.37 *** 0.48 *** 0.57 *** 0.39 *** 0.41 0.11
IL6R 0.24 *** 0.22 *** 0.20 *** 0.27 *** 0.19 *** 0.05 *
SPIB 0.25 *** 0.34 *** 0.25 *** 0.36 *** 0.35 *** 0.61 *
SPP1 5.55 *** 5.47 *** 8.67 *** 3.46 *** 5.85 *** 2.24 0.13
TCN1 5.16 *** 1.09E+07 * 11.70 *** 3.29 *** 4.03E+3 0.1 4.85E+40 0.48
April 28, 2014 國醫公衛所 9
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April 28, 2014 國醫公衛所 10 10
21基因時,測試樣本 AUC值最高(0.74)
21基因時,測試樣本 AUC值最高(0.74)
Cox-regression analysisCox-regression analysis
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April 28, 2014 國醫公衛所 11
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in course of Health Informatics
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April 28, 2014 國醫公衛所 14
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April 28, 2014 國醫公衛所 15
CPI = Cardiac Output per Heartbeat
15