© 2015 pearson education, inc. figure 5-1 the components of the integumentary system. epidermis...
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© 2015 Pearson Education, Inc.
Figure 5-1 The Components of the Integumentary System.
Epidermis
Cutaneous Membrane
Papillary layer
Reticular layer
Dermis
Hypodermis
Hair shaft
Pore of sweatgland duct
Tactile (Meissner’s)corpuscle
Sebaceous gland
Arrector pili muscle
Sweat gland duct
Hair follicle
Lamellated (pacinian) corpuscle
Nerve fibers
Sweat gland
Artery
VeinCutaneous plexus
Fat
Accessory Structures
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Figure 5-2 The Cutaneous Membrane and Accessory Structures.
Integumentary System
Cutaneous Membrane Accessory Structures
Epidermis Dermis
Papillary Layer Reticular Layer
Hair Follicles Exocrine Glands Nails
FUNCTIONS
Protects the dermis,prevents water loss andthe entry of pathogens,and synthesizes vitaminD3. Sensory receptors
detect touch, pressure,pain, and temperature
Nourishes andsupports epidermis
Has sensory receptors
that detect touch,
pressure, pain, vibration,
and temperature. Blood
vessels assist in
thermoregulation
Hairs protectskull and providedelicate touchsensations ongeneral bodysurface
Assist intemperatureregulation andwasteexcretion
Protect andsupport tipsof fingersand toes
• Physical protection fromenvironmental hazards
• Storage of lipids
• Coordination of immuneresponse to pathogensand cancers in skin
• Sensory information• Synthesis of vitamin D3
• Excretion• Thermoregulation
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The structural relationship andinterface between the epidermisand underlying dermis. Theproportions of the various layersdiffer with the location sampled.
Dermis
Epidermis
Epidermalridge
Dermalpapilla
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Figure 5-2b The Basic Organization of the Epidermis
A micrograph ofthin skin, which covers most ofthe exposedbody surface.
Stratumcorneum
Basementmembrane
Dermis
Thin skin LM 154
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Figure 5-3 The Epidermis (Part 2 of 3).
Surface
Basementmembrane
Stratumcorneum
Stratumlucidum
Dermalpapilla
Epidermalridge Thick skin LM × 200
Epidermis
Stratum corneum
Characteristics
Dermis
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale
• Multiple layers of flattened, dead,interlocking keratinocytes
• Water resistant but not waterproof• Permits slow water loss by insensible
perspiration
• Appears as a glassy layer in thick skinonly
• Keratinocytes produce keratohyalin andkeratin
• Keratin fibers develop as cells becomethinner and flatter
• Gradually the plasma membranes thicken,the organelles disintegrate, and the cells die
• Keratinocytes are bound together bydesmosomes
• Deepest, basal layer• Attachment to basement membrane• Contains basal cells (stem cells),
melanocytes, and tactile cells (Merkel cells)
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Copyright © 2009 Pearson Education, Inc., publishing as Pearson Benjamin Cummings
Figure 5-3 The Structure of the Epidermis
Thick skin LM 210
Surface
Stratumcorneum
Stratumlucidum
Stratumgranulosum
Stratumspinosum
Stratum basale
Basementmembrane
DermisPapillary layer of dermis
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Figure 5-4 The Epidermal Ridges of Thick Skin
Thick skin SEM 25
Epidermalridge
Pores of sweatgland ducts
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Figure 5-5 Melanocytes
Melanocytes LM 600
Melanocytes in stratum basale
Melaninpigment
Basementmembrane
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Figure 5-5 Melanocytes
Basementmembrane
Melanosome
Keratinocyte
Melanin pigment
Melanocyte
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Figure 5-1 The Components of the Integumentary System
Cutaneous MembraneAccessory Structures
Epidermis
Dermis
Papillary layer
Reticular layer
Hypodermis
Hair shaft
Pore of sweatgland duct
Tactile corpuscle
Sebaceous gland
Arrector pili muscle
Sweat gland duct
Hair follicle
Lamellated corpuscle
Nerve fibers
Sweat gland
Artery
Vein
Fat
Cutaneousplexus
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Figure 5-10 Dermal Circulation.
Hair
Papillarylayer
Reticularlayer
Cutaneousplexus
Lymphaticvessel
Subpapillaryplexus
Capillary loop ofsubpapillary plexus
Dermalpapillae
Epidermalridges
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The Epidermal Ridges of Thick Skin
Thick skin SEM 25
Epidermalridge
Pores of sweatgland ducts
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Figure 5-9 Cleavage Lines of the Skin
ANTERIOR POSTERIOR
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Figure 5-12a Hair Follicles and Hairs.
Sebaceousgland
Arrectorpili muscle
Connectivetissue sheath
Hair
Root hairplexus
Hair follicles, showingthe associatedaccessory structures
a
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Figure 5-12b Hair Follicles and Hairs
Cross section through ahair follicle and a hair, nearthe junction between thehair root and hair shaft.
Connective tissue sheath
Hair Structure
Follicle Structure
The medulla, or
core, of the hair
contains a flexible
soft keratin.
The cortex contains thick
layers of hard keratin,
which give the hair its stiff-
ness.
The cuticle, although
thin, is very tough, and
it contains hard keratin.
The internal root sheath surroundsthe hair root and the deeper portion ofthe shaft. The cells of this sheathdisintegrate quickly, and this layer doesnot extend the entire length of the hairfollicle.
The external root sheath extendsfrom the skin surface to the hair matrix.
The glassy membrane is a thickened,clear layer wrapped in the denseconnective tissue sheath of the follicleas a whole.
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Figure 5-12c Hair Follicles and Hairs.
Hair shaft
External root sheath
Connective tissuesheath of hair follicle
Internal root sheath
Glassy membrane
Cuticle of hair
Cortex of hair
Medulla of hair
Matrix
Hair papilla
Subcutaneousadipose tissue
Hair follicle
c Histological section along thelongitudinal axis of hairfollicles
LM × 60
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Figure 5-12d Hair Follicles and Hairs.
Hair papilla
Connective tissuesheath of hair follicle
Glassy membrane
External root sheath
Internal root sheath
Cuticle of hair
Cortex of hair
Medulla of hair
Matrix
Hair bulb
Subcutaneousadipose tissue
d Diagrammatic view of thebase of a hair follicle© 2015 Pearson Education, Inc.
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Figure 5-13 The Structure of Sebaceous Glands and Sebaceous Follicles
Epidermis
Dermis
Subcutaneouslayer
Sebaceous follicle Sebaceous gland
Sebaceous gland LM 150
Basal cells
Mitosis and growth
Breakdown ofcell membranes
Lumen
Discharge ofsebum
Basementmembrane
Lumen(hair removed)
Wall of hair follicle
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Figure 5-14a Sweat Glands
Apocrine sweat glandssecrete a thick, odorousfluid into hair follicles.
LM 459Apocrine sweat gland
Lumen
Myoepithelial cell
Connectivetissue of dermis
Apocrinegland cells
Duct ofapocrine
sweat gland
Sectional planethrough apocrine
sweat gland
A sectionthrough a merocrinesweat gland
Sweat pore
Duct
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Figure 5-14b Sweat Glands
Duct ofapocrine
sweat gland
Sectional planethrough apocrine
sweat gland
A sectionthrough a merocrinesweat gland
Sweat pore
Duct
Merocrine sweat glandsdischarge a watery fluidonto the surface of theskin.
LM 243Merocrinesweat gland
Lumen
Myoepithelialcells
Merocrinegland cells
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Figure 5-15 The Structure of a Nail
A longitudinal section
A superficial view
A cross-sectional viewEponychium
Proximalnail fold
Lunula
Nail body
Lateral nail fold
Free edge
Directionof growth
Nailbody
Lateralnail
groove
Nailbed
Phalanx(bone of
fingertip)
Eponychium
Proximal nail fold
Nail root
Lunula Nail body
Epidermis Dermis Phalanx Hyponychium
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Figure 5-13c The Structure of a Nail
A longitudinal section
Eponychium
Proximal nail fold
Nail root
Lunula Nail body
Epidermis Dermis Phalanx Hyponychium
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Figure 5-16 Repair of Injury to the Integument (Part 1 of 4).
Epidermis
Dermis
Mast cells
Inflammatory Phase1
Bleeding occurs at the siteof injury immediately afterthe injury, and mast cells in the region trigger aninflammatory response.
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Figure 5-16 Repair of Injury to the Integument (Part 2 of 4).
Migratingepithelialcells
Macrophagesand fibroblasts
Granulationtissue
Migratory Phase2
After several hours, ascab has formed and cellsof the stratum basale aremigrating along the edgesof the wound. Phagocyticcells are removing debris,and more of these cellsare arriving with theenhanced circulation inthe area. Clotting aroundthe edges of the affectedarea partially isolates theregion.
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Figure 5-16 Repair of Injury to the Integument (Part 3 of 4).
Fibroblasts
Proliferation Phase3
About a week after the injury, the scab has beenundermined by epidermalcells migrating over thecollagen fiber meshworkproduced by fibroblastproliferation and activity.Phagocytic activityaround the site hasalmost ended, and thefibrin clot is dissolving.
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Figure 5-16 Repair of Injury to the Integument (Part 4 of 4).
Scartissue
Scarring Phase
After several weeks, thescab has been shed, andthe epidermis is complete.A shallow depressionmarks the injury site, butfibroblasts in the dermiscontinue to create scartissue that will graduallyelevate the overlyingepidermis.
4
4
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A Quick Method of Estimating the Percentage of Surface Area Affected by Burns
Head 9%
Upper limb9% each
Trunk 36%(front and back)
Genitalia 1%
Lower limb18% each
Head 15%
Trunk 32%(front and back)
Lower limb17% each
Upper limb 9% each
Genitalia 1%
ADULT CHILD (5-year-old)
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