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X-RAY CRYSTALLOGRAPHY

Presented By, Sharon .J. Roy

Dept. of pharmaceutical Analysis Sub: Modern analytical and Research methods

Grace college of pharmacy, Palakkad

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ELEMENTARY CRYSTALLOGRAPHY

CRYSTALLOGRAPHY : Science of study of crystal study.

CRYSTAL : A homogenous solid formed by repeating 3dimensional pattern of atoms, ions or molecules & having smooth external surface

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ELEMENTARY CRYSTALLOGRAPHY

LATTICE- is a representation of crystal structure as an array of points in space.

UNIT CELL- is defined as the fundamental pattern of minimum number of atoms or molecules which represent the full character of the crystal.

LATTICE PLANES- parallel equidistant planes passing through the lattice points

PREMITIVE CELL : Atoms at the corners but not in the middle of phases , not in the centre of cell..

NON PREMITIVE CELL : 3 Types, Body centred (I) Face centred (F) End centred (C)

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b

a

c

α

β

γ

A UNIT CELL

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CRYSTAL SYSTEMS

ORTHORHOMBIC

RHOMBOHEDRAL

TETRAGONA

LCUBIC

HEXAGONA

L

MONOCLINIC

TRICLINIC

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X-RAY CRYSTALLOGRAPHY

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INSTRUMENTATION Crystals must be…. Small in size Perfect Different substance crystallize differently

Mounting crystal…. Exposing X- Rays…. Reflections…. Electron density map….

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