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Conversion to open procedure: Decision making, treatment, tips & tricks Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery San Raffaele Scientific Institute – Milan, Italy

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Page 1: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Conversion to open procedure:

Decision making, treatment, tips & tricks

Vascupedia@LINC: Endoleaks–case-based solutions

Roberto ChiesaDirector, Dept. of Vascular Surgery

San Raffaele Scientific Institute – Milan, Italy

Page 2: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Conflict of interest

Nothing to disclose

Page 3: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

EVAR vs Open

EVAR has no advantage on survival!

Salata K. et al. JAMA Net Open –Surgery - 2019

Page 4: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

EVAR vs Open

.. but higher need of secondary procedures!

Salata K. et al. JAMA Net Open –Surgery - 2019

Page 5: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Endoleak

Durability

Migration

EVAR unsolved issues

Page 6: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

ACE (299 pts)

DREAM (351 pts)

EVAR1 (1,252 pts)

MEDICARE (45,560 pts)

OVER (881 pts)

SwedVasc (3,777 pts)

ENDO vs OR: long-term

Stather et al, Br J Surg 2013

reinterventions

(OR = 2)

AAA rupture

(OR = 6)

Meta-analysis (52,220 pts)

AAA rupture @ 4 yrs

Reinterventions @ 4 yrs

EVAR

Page 7: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Late ruptured AAA after EVAR

Proximal type I EL with retroperitoneal hematoma

Chiesa R et al. European Vascular Course Text Book & Acta Chir Belg 2006

3 years after EVAR

AneuRX

Page 8: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Trend of open conversion

2010-2015

Growing rate of EVAR

Moulakakis et al J Endovasc Ther 2010

Kouvelos et al J Vasc Surg 2015

Secondary procedures

Late open conversions

1.9%

4 %

Page 9: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

OSR personal experience

2005-2019

1487 EVAR procedures

23 Open conversion *

*1.5 %

Page 10: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Tot. 84 pts

Open conversion after EVAR

23 pts

OSR

*27%

61 pts

other centers

*73%

OSR global experience

2005-2019

Page 11: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Causes of open conversion

Endoleak I - III 45

Endoleak II 21

Occlusion 7

Graft failure 5

Infection 4

Migration 2

Page 12: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

..it’s time for surgical conversion!

When EVAR fails …

Page 13: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Surgical approach after EVAR

Saccotomy

Laparoscopic ligation

Partial endograft removal

Complete endograft removal

Lumbar artery

Page 14: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Saccotomy

Laparoscopic ligation

Partial endograft removal

Complete endograft removal

Surgical approach after EVAR

Page 15: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Surgical approach after EVAR

Saccotomy

Laparoscopic ligation

Partial endograft removal

Complete endograft removal

Page 16: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Surgical approach after EVAR

Saccotomy

Laparoscopic ligation

Partial endograft removal

Complete endograft removal

Page 17: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Technique: surgical accesses

8%

44%

48%

Median laparotomy

Bilateral subcostal laparotomy

Thoraco-phreno-laparotomy

Page 18: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Infrarenal: 47% Suprarenal: 42% Supraceliac:11%

Technique: clamping site

Page 19: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

62 y.o. male

2012: EVAR (Gore Excluder)

Type II endoleak

(IMA and lumbar)

2013-14: Previous embolizations

2015: Rapid sac enlargement

Case #1

Main body complete removal

Page 20: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Case #1

Main body complete removal

Page 21: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

But… endograft configuration

30%

27%43%

No free-flow

Free-flow

Free-flow + barbs

57%

Page 22: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Aortic dissection

Aortic endoarterectomy

Renal dissection

Renal ischemia

Renal embolization

Main body complete removal

may cause…

Page 23: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Complete removal (stent+barbs)

LRA

RRA

Bilateral renal artery bypass Bilateral renal occlusion after conversion

Page 24: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

71 y.o. female

2013: EVAR (Trivascular Ovation)

Type II endoleak

2015: Embolization

2016: Rapid sac enlargement

Case #2

Main body partial removal

Page 25: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Case #2

Main body partial removal

Page 26: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Focus on the technique:

Proximal anastomosis(when stent-graft is partially removed)

“Triple-layer technique”

Page 27: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Pruitt catheters limb occlusion

Focus on the technique:

Distal anastomosis(with iliac limbs preservation)

Page 28: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Case#3

Nellix (EVAS) open conversion

78 y.o. male

2016: EVAS (Nellix)

2018: Graft migration

with sac reperfusion

and abdominal pain

Page 29: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Case#3

Nellix (EVAS) open conversion

Page 30: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Case#3

Nellix (EVAS) open conversion

Polymer disruption

Page 31: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Open conversion: results

Total 84

Renal insufficiency 5 (5.9 %)

Respiratory failure 8 (9.5 %)

In-hospital mortality 2 (2.4 %)

Page 32: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Open conversion: results

Complete removal

Partialremoval

Saccotomy

Patients 38 (45 %) 43(51 %) 3 (3.6 %)

Renal

Insufficiency4 (10 %) 1 (2.3 %) 0

In-hospital

Mortality1(2.6 %) 1 (2.3 %) 0

Page 33: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Conclusions

Page 34: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Open conversion after EVAR

• Technical challenging

• Mortality and morbidity rates acceptable in

high volume centres for open repair

• Partial removal of the stent-graft offers reduced

renal morbidity

• Careful patient selection and follow-up after

EVAR

Page 35: Vascupedia@LINC: Endoleaks case-based solutions · Vascupedia@LINC: Endoleaks–case-based solutions Roberto Chiesa Director, Dept. of Vascular Surgery ... 2010-2015 Growing rate

Conversion to open procedure:

Decision making, treatment, tips & tricks

Vascupedia@LINC: Endoleaks–case-based solutions

Roberto ChiesaDirector, Dept. of Vascular Surgery

San Raffaele Scientific Institute – Milan, Italy