ttopstart academy - getting nih funding as a european researcher or company
TRANSCRIPT
• Webinar• Opportunities for orphan drug
development in Horizon 2020© ttopstart [email protected]
How to get NIH funding as a non-US entity
ttopstart academy
January 2016
Ferdinand Los, PhD – consultant @ ttopstart
For every € 100 from Horizon 2020 for life sciencesthe NIH spends another $ 15 in Europe
$$
This is a guide to NIH grants for non-US entities
Empowering biomedical researchers andentrepreneurs to establish breakthroughs
The National Institutes of Health (NIH) is the primary U.S. agency
responsible for biomedical and health-related research. The NIH provides
major research funding to non-NIH research facilities, including foreign
institutions and international organisations.
The NIH research budget in 2014 was $24B, approximately $1.3B is spent
outside the US and of that, $175M in Europe.
This presentation aims to guide non-US entities to NIH funding:
• How to determine whether you meet the requirements for eligibility
• How to identify which type of NIH grant fits you best
• Where to search for Funding Opportunity Announcements (FOAs) and
specific topics that match your envisioned project
Introduction
NIH
In general,
• eligible institutions can be higher education, government, non-profitand for-profit organisations and institutions.
The NIH usually accepts applications both by individual researchers andby research consortia, for all types of programs and calls.
General criteria on eligibility are provided in sections III.1.A and III.1.B ofeach FOA, describing the suitable type of institutions or individuals
General requirements for applicants
NIH
For non-US applicants the following will be assessed:
• Does the project employ unusual talents, resources, populations, orenvironmental conditions that are not readily available in the U.S.that either facilitate further research or augment existing resources?
• Is the proposed project specifically relevant to the mission andobjectives of the NIH and does it have the potential to significantlyadvance health sciences in the U.S?
Additional information on the requirements for non-US applicants maybe found here.
Specific requirements for non-US applicants
NIH
Types of NIH programs
NIH
R01 specified research project 3-5 years No set budget, typically
$250k a year
R03 limited funding for a short period 2 years $50k a year
R21 early stage research 2 years $275k total
R34 phase III clinical trials 1 year $100k
U01 specified research project, by
investigator(s) in their specific area of
interest and competencies
No set budget
P01 multi-project research projects No set budget
The NIH accepts both unsolicited grant applications as well as responsesto specific calls. Unsolicited programs are investigator-initiated andbottom-up, open to any kind of project. For both types of applications,the NIH has a number of grant programs or instruments. Non-US entitiesare eligible to apply for a subset of these:
• R01 - discrete, specified, circumscribed research projects
• R03 - limited funding for a short period, including: pilot or feasibilitystudies, collection of preliminary data, secondary analysis of existingdata, small, self-contained research projects, development of newresearch technology, etc.
• R21 - exploratory and developmental research projects
• R34 - phase III clinical trials
• U01 - discrete and specified research projects, to be performed byinvestigator(s) in their specific area of interest and competencies
• P01 - integrated, multi-project research projects involving differentindependent investigators. Open to non-US applicants under specificconditions, mentioned in FOAs
Types of NIH programs
NIH
NIH is made up of 27 Institutes and Centers, each with a specificresearch agenda, often focusing on particular diseases or body systems.Based on the research topic, the grant application is send to one of theseinstitutes. For instance the:
• National Cancer Institute (NCI)
• National Institute on Aging (NIA)
• National Institute of Allergy andInfectious Diseases (NIAID)
NIH institutions
NIH
Open calls can be found through different means:
• For unsolicited grant applications there are so-called parent FOAs.
• All U.S. grants are published through this website.
• Relevant NIH-calls can also be found in the ttopstart database, listedby topic.
Certain FOAs describe specific objectives and expected outcomes. Inother cases, there are no specific program requirements, but theproposed research plan must be related to the stated program interestsof one or more of the 27 NIH Institutes and Centers.
Specifics and exceptions are found in the FOA descriptions.
Funding Opportunity Announcements and specific topics
NIH
Generally, NIH grants cycle through three annual deadlines, details ofwhich may be found here. For the relevant programs, the deadlines areoutlined below.
Submission deadlines
NIH
R01, U01 February 5 June 5 October 5
R03, R21, R34 February 16 June 16 October 16
P01 January 25 May 25 September 25
The ttopstart team
NIH
ttopstart is a science and business consulting company thatserves leading researchers and innovative companies in thefields of life sciences and medical technology.
Our excellent track-record is attributable to:
• Our broad technological and scientific knowledge
• Our business development background
• Our in-depth knowledge of subsidy programmes
• Our structured approach
• Our writing skills
About ttopstart
NIH
ttopstart offers a balanced set of funding and business development services, all dedicated to biomedicalresearchers and entrepreneurs.
ttopstart services
NIH
Prepare
Funding strategy
Develop
Proposal writing
PRO-ACTIV• Analysis• Customised strategy• Training & Implementation• Valuation
FFWD• Fit• Framework • Write • Develop
Empower your team to excel Reach a 50% success rate
Execute
Project management
• Management• Dissemination• Exploitation
Focus on the science
Exploit
Business development
Check our funding database:
www.ttopstart.com/subsidies/database
ttopstart BV
P.C. Staalweg 303721 TJ BilthovenThe Netherlands+31 (0)30 73 70 779
Our services• Subsidies• Business development• Project managementFor life sciences and medical technology
The ttopstart team:Patrick de Boer, MScJochem Bossenbroek, MScir. Jasper LevinkSanne Kuijper, PhDMarije aan den Toorn, PhDFerdinand Los, PhDJean-Pierre Sommeijer, PhDMichelle van Wijk, MScAndrée Schram, PhDGeorgia Xouri, PhDAntoin de Weijer, PhDKarlijn Bastiaansen, PhDKarin Bosch-Elberse, PhDJelle Zijlstra, MScAnouk IJlst, MA