transplant in inborn errors of metabolism inborn errors of metabolism • list common metabolic...

Download Transplant in Inborn Errors of Metabolism inborn errors of metabolism • List common metabolic conditions

Post on 21-Oct-2019




0 download

Embed Size (px)


  • Garrod Symposium 2018

    Transplant in Inborn Errors of Metabolism

    May 10 -12, 2018

    In cooperation with


    Fairmont Hotel MacDonald Edmonton, AB



    The meeting will be held at the Fairmont Hotel MacDonald (10065 100 St., Edmonton, AB). A special rate of $229.00 for a standard guest room (Fairmont Room: single/double occupancy) is available for conference delegates. To avoid disappointment, book by calling toll-free: 1.800.257.7544 or Local: +1.780.424.5181, please specify that you are booking under the Garrod Symposium 2018 room block to receive these reduced rates.


    ONLINE: The quickest, most secure method is registering online. Registration is available for Visa/MasterCard holders at the meeting organizer’s website:

    BY FAX: Fax your completed registration form to: 1-604-822-4835

    PHONE REGISTRATION: Toll free within North America: 1-855-827-3112; other callers: 1-604-827-3112

    MAIL: Send the registration form with cheque to this address:

    IN 9580 REGISTRATION, Interprofessional Continuing Education, The University of British Columbia, Room 105-2194 Health Sciences Mall, Vancouver, BC, V6T 1Z3, Canada

    Participants paying by credit card outside of North America: Please inform your credit card company of the transaction as some banks put a block on credit card payments made outside your country.


    Please see the registration form (last page) for details. The tuition fee includes: welcome reception (May 10), breakfast (May 11 & 12), lunch (May 11 & 12), webinars and workshops (May 10-12), Garrod Association membership rate (if selected) and a certificate of attendance. Registration for the dinner event on Friday will also be available at an extra cost. Pre-registration before/on April 6, 2018 is strongly recommended to take advantage of the early-bird rate. To qualify for the Garrod Association member’s rate, one must pay the fee for membership dues during the registration process.

    We will be including presenter slides (if the presenter permits) in our meeting program. We will send this program to you electronically (for free) a few days prior to the meeting but if you wish to purchase the paper copy that will be distributed on-site, please select the $20 option on the registration page.


    Notifications of cancellations must be sent by email to on or before April 6, 2018 in order for registration fees to be refunded. If you have been invoiced but not paid the fees, you are still liable to pay the cancellation charges below:

    • Up to and including April 6, 2018: Registration fee will be refunded less 20% cancellation fee. • After April 6 2018: No refunds on registration fees will be made. Substitutions can be made.

    CREDITS This conference has been approved by the Canadian Association of Genetic Counsellors (CAGC) for 12.58 CECs.

    For additional information and updates regarding credits, please refer to the symposium organizer’s website:

    CONTACT For additional enquiries, please contact Jo at 604-822-0054 or

    G E N E R A L I N F O R M A T I O N


    By the end of the meeting participants will be able to:

    • Understand and outline the indications for different types of transplants in inborn errors of metabolism

    • List common metabolic conditions where transplant is considered a beneficial therapeutic option

    • Describe expected benefits and change in management following a successful transplant in at least 5 metabolic conditions

    • Understand the scope of transplant in metabolic cardiac disorders

    Please note: 25% of the scientific program will be interactive.

  • MAY 10 - 12, 2018 | EDMONTON, AB 3



    The Garrod Association and the Program Committee gratefully acknowledge the generous contributions and financial support from the following organizations:




    12:00 Registration Open

    12:30- 14:30

    CIMDRN Meeting (Invitation Only) (Room: Drawing Room)

    14:30 - 16:00

    Garrod Executive Committee Meeting (Invitation Only) (Room: Cavonagh Boardroom)

    14:30- 16:00

    Nurse/Genetic Counselor Webinar (Room: Drawing Room)

    Advances in Laboratory Diagnosis of Lysosomal Storage Disorders Tim Wood, PhD, FACMG, Director, Metabolic Laboratory, Greenwood Genetic Center, Greenwood, SC, USA

    1. Comprehend the general process of enzymatic assays commonly used for the diagnosis of LSDs

    2. Recognize the limitations of urinary screening assays particularly for the MPS disorders

    3. Compare an enzyme-first testing strategy with the classic screening strategies for identifying patients with a lysosomal storage disorder

    4. Integrate molecular testing into testing for LSDs 5. Assess how novel urinary testing methods can

    improve/enhance treatment monitoring

    14:30- 16:30

    Dieticians’ Webinar (Room: Jasper Room)

    Dietary Management in MMA, PA and MSUD: Focus on Transplantation Gregory Enns, MB, ChB, Director, Biochemical Genetics Program, Department of Pediatrics, Stanford University, Stanford, CA, USA

    1. Discuss perioperative nutrition in liver transplantation for patients with MMA, PA, and MSUD

    2. Describe natural and metabolic protein tolerance pre vs post-transplant in MMA, PA, and MSUD

    The session will conclude with discussion of three case studies to highlight nutritional aspects of liver transplantation in inherited metabolic disorders.

    16:00- 17:15

    Plenary Session I: Bone Marrow Transplant (Room: Empire Ballroom)

    Introduction and Welcome to the Meeting Shailly Jain, MD, FRCPC, FCCMG, Clinical Geneticist & Metabolics Specialist, Associate Professor, Edmonton Medical Genetics Clinic, University of Alberta, Edmonton, AB

    Hematopoietic Cell Therapy for Lysosomal and Peroxisomal Disorders Paul Orchard, MD, Medical Director, Inherited Metabolic & Storage Disease Bone Marrow Transplantation Program; Professor, Division of Pediatric Blood and Marrow Transplantation, Pediatric Blood & Marrow Transplantation Center, University of Minnesota, Minneapolis, MN

    1. Understand the rationale for the use of hematopoietic transplanataion for inborn errors

    2. Recognize the risks and limitations of transplanatation 3. Have an appreciation for emerging issues related to

    newborn screening


    17:15- 18:00

    Platform Presentations (Selected Abstracts) Three abstracts (15 minutes each)

    18:30- 20:00

    WELCOME RECEPTION (Room: Mezzanine Level)

    PROGRAM THURSDAY May 10, 2018

  • MAY 10 - 12, 2018 | EDMONTON, AB 5


    May 11, 2018

    7:00- 8:00

    Registration Open & Breakfast (Provided) (Room: Jasper Room & Drawing Room)

    8:00- 9:30

    Plenary Session II: Liver Transplant (Room: Empire Ballroom)

    Liver Transplantation: The Modern Era Patricia Kawada, Clinical Lecturer, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB

    1. Review Indications for liver transplantation 2. Current liver transplantation listing and allocation in

    Canada 3. Surgical anatomy of liver transplantation 4. Outcomes of liver transplantation

    Transplants in Patients with Inborn Errors of Metabolism Aneal Khan, MD, MSc, FRCPC, FCCMG, Associate Professor, Department of Medical Genetics and Paediatrics, Alberta Children’s Hospital Research Institute, Cumming School of Medicine, University of Calgary, Metabolic Diseases Clinic, Calgary, AB

    1. Understanding diverse use of transplants in patients with inborn errors of metabolism

    2. Understanding that there are continuous medical issues that need to be monitored after transplant

    3. To anticipate future challenges in transplant


    9:30- 10:00

    Refreshment Break & Exhibitors & Posters (Mezzanine Level)

    10:00- 11:50

    Plenary Session III: Liver Transplant in Urea Cycle Disorders (Room: Empire Ballroom)

    Liver transplant experience for Urea Cycle disorders in western Canada Alicia Chan, FRCP (C), FCCMG, Clinical Geneticist and Metabolics Specialist, Associate Professor, Edmonton Medical Genetics Clinic, University of Alberta, Edmonton, AB

    1. Describe the experience of liver transplantation for Urea Cycle disorders in western Canada

    2. Describe the changes in liver transplantation for Urea Cycle disorders in western Canada from past to the present

    The Toronto Experience in Liver Transplantation for Urea Cycle Disorders – Patient Selection and Outcome Yaron Avitzur, MD, Medical Director, Intestinal Rehabilitation and Transplantation, Gastroenterology, Hepatology and Nutrition; Director, Paediatric Gastroenterology Training Program, Gastroenterology, Hepatology and Nutrition; Staff Gastroenterologist, Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children; Associate Professor, Department of Paediatrics, Faculty of Medicine, University of Toronto, Toronto, ON

    1. Describe the experience of liver transplantation for UC


View more >