The Molecular Times.Jonathan Rendón ZMedicine student.

introductionActually scientists are looking for genetic treatments to avoid the disease to happen. This is known as medical genetics and this is exactly as medicine is reaching its future.

All of the recent studies are aiming to a common target, apply genetics (DNA expression, transmission and regulation) to medical care, creating new therapies and predicting disease. 

Scientists Bring Cancer Cells Back Under Control  ScienceDaily January 18, 2011

 

Cancers occur when the mechanisms that control normal cell division are mutated.

The process of cell division is controlled by specific genes and these are turned "on" or "off" depending on their function.

Scientists Bring Cancer Cells Back Under Control

Among the most important of these genes are tumor suppressor genes.

The reactivation of tumor suppressor genes can stop cancer from growing by treating them with Axolotl oocyte extract.

Scientists Bring Cancer Cells Back Under Control

After 60 days there was still no evidence of cancerous growth.

Tumor suppressor genes in many breast cancers are switched off by epigenetic marks, which is the underlying cause of tumors.

Scientists Bring Cancer Cells Back Under Control

Extracts prepared from these oocytes have powerful capacity to change epigenetic marks on the DNA of human cells.

The identification of the proteins responsible for this tumor reversing is a major goal of future research aimed for the cancer treatment. 

Observation.

Scientists are doing their best finding a cure not in the pharmacological field but in the genetic and molecular and trying to avoid any collateral damage known this days due to genetic manipulation and experimentation. 

Genetic Sequencing Alone Doesn't Offer a True Picture of Human Disease, Research Suggests  ScienceDaily January 24, 2011 

 

Right now the paradigm is to sequence a number of patients and see what may be there in terms of variants

Genetic Sequencing Alone Doesn't Offer a True Picture of Human Disease, Research Suggests 

"We have to know the extent to which gene variants in question are detrimental. Every patient has its own set of genetic variants, and most of these will not be found at sufficient frequency in the general population so that anyone could make a clear medical statement about their case."

Genetic Sequencing Alone Doesn't Offer a True Picture of Human Disease, Research Suggests 

"By sequencing genes to identify genetic variation, followed by functional studies with a good experimental model, we can get a much better idea of the architecture of complex inherited disorders"

Genetic Sequencing Alone Doesn't Offer a True Picture of Human Disease, Research Suggests 

"If you can overlay gene sequencing with functional information, then you will be able to increase the fidelity of your findings and it will become more meaningful for patients and families."

Observation.

Genetic diagnosis provides information about the genetic basis of inherited diseases; variants needs to be known, in order to find out predisposition on the patients and mode of inheritance. Once this is done an accurate diagnosis, treatment and prognosis can be made. 

Medical utility

Cancer arises from just a molecular change on one cell started by external and inherited genetic factors. Lung, stomach, liver, colon and breast cancer cause most of deaths each year and about 30% of them can be prevented. 

Medical utility

Certain cancers are caused by some factors that medical genetics should use such as viruses, bacteria and parasites engineering them to be beneficial for human health. 

Medical utility

At long term, genetics will become the most useful diagnosis aid, allowing doctors to find what would be wrong with a patient and preventing each disease, and most important inherited disease (like cancer) or cellular mutations due to molecular changes. 

Bibliography

•Scientists bring cancer cells back under control ScienceDaily. (Jan, 18, 2011)

•Genetic sequencing alone doesn't offer a true picture of human disease, research suggests ScienceDaily (Jan, 24, 2011) 

Thank you!.