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Survey and health assesment of thiourea compounds in chloroprene rubber Survey of chemical substances in consumer products no. 118, 2012

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Page 1: Survey and health assesment of thiourea compounds in ... · Survey and health assesment of thiourea compounds in chloroprene rubber Survey of chemical substances in consumer products

Survey and health assesment of thiourea compounds in chloroprene rubber Survey of chemical substances in consumer products no. 118, 2012

Page 2: Survey and health assesment of thiourea compounds in ... · Survey and health assesment of thiourea compounds in chloroprene rubber Survey of chemical substances in consumer products

2 Survey and health assesment of thiourea compounds in chloroprene rubber

Title:

Survey and health assesment of thiourea

compounds in chloroprene rubber

Authors & contributors:

COWI A/S: Carsten Lassen, Sonja Hagen Mikkelsen og Ulla Kristine

Brandt,

Teknologisk Institut (Danish Technological Institute): Eva Jacobsen

Publisher:

Miljøstyrelsen

Strandgade 29

1401 København K

www.mst.dk

Year:

2012

ISBN no.

978-87-92903-27-3

Disclaimer:

The Danish Environmental Protection Agency will, when opportunity offers, publish reports and contributions relating to

environmental research and development projects financed via the Danish EPA. Please note that publication does not

signify that the contents of the reports necessarily reflect the views of the Danish EPA. The reports are, however,

published because the Danish EPA finds that the studies represent a valuable contribution to the debate on

environmental policy in Denmark.

May be quoted provided the source is acknowledged.

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NP= h~ó~âáåÖ=ÖäçîÉë== U=ÜçìêëLÇ~ó= fí=áë=~ëëìãÉÇ=íÜ~í=íÜÉ=ÖäçîÉë=ïçìäÇ=ÄÉ=ìëÉÇ=çå=Ç~ó=íêáéë=ìé=íç=U=ÜçìêëK=

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ëìÄëí~åÅÉëI=~=ëìÑÑáÅáÉåí=Ç~í~=Ä~ëÉ=çê=éçëëáÄáäáíó=íç=ÇÉíÉêãáåÉ=~=íÜêÉëÜçäÇ=î~äìÉ=

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1 DNEL, Derived No Effect Level, expresses the level of exposure below which no health effects

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threshold below which one can say that there are no health effects.

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Page 60: Survey and health assesment of thiourea compounds in ... · Survey and health assesment of thiourea compounds in chloroprene rubber Survey of chemical substances in consumer products

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Summary

Chloroprene rubber, which is also known as “neoprene”, is a synthetic rubber that is used for both

technical and consumer products. The main application areas are water sports products and bandages.

According to the literature, a number of thiourea compunds are used as accelerators in the

manufacturing of chloroprene rubber products. Six of these have been identified as potentially giving

rise to allergic reactions. DETU was present in concentrations of 33 to 720 mg/kg in 10 of the 14

examined products and is of the same magnitude as the concentrations in products that are

demonstrated to cause contact dermatitis in sensitized individuals.