2019 on a postcardPublications 18

Nights turned into day 73

in SCI/SSCI/PubMed listed journals

DNi

Development(al regression)A prominent warning signal for atypical childhood trajectory | losing abilities and skills that were once mastered | a red flag for parents, teachers, and clinicians | loss of functions | affecting the developing nervous system | paving the way towards a common consensual approach for the interdisciplinary study on developmental regression

Special Issue in Neuroscience and Biobehavioral Reviews 2019 on Regression in Neurodevelopmental and Genetic Disorders [ed. PB Marschik & S Bölte]

Presentations 44

Zika virusWe reported neurodevelopmental outcomes in 216 infants followed since the time of PCR-confirmed maternal Zika virus infection in pregnancy during the Rio de Janeiro epidemic of 2015-2016.Nielsen-Saines K, Brasil P, Kerin T, et al. Delayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children. Nat Med. 2019; 25(8): 1213-1217.

peter.marschik@medunigraz.at www.idn-research.org idn-research idn_research © 2020 iDN

Cerebral palsyOur study demon-strated that use of the Motor Optimal-ity Score (MOS) c o n t r i b u t e s t o understanding later c e r e b r a l p a l s y prognosis, including early markers for type and severity.

Einspieler C, Bos AF, Krieber-Tomantschger M, ..., Marschik PB. Cerebral palsy: Early markers of clinical phenotype and functional outcome. J Clin Med. 2019; 8(10).

Rett syndromeRecent evidence suggests that we are on the right track towards defining new and reliable neurofunctional markers for early detection of Rett syndrome, paving the way for an earlier entry into intervention.Einspieler C, Marschik PB. Regression in Rett syndrome: Developmental pathways to its onset. Neurosci Biobehav Rev. 2019; 98: 320-332. | Sigafoos J, O'Reilly MF, Ledbetter-Cho K, ..., Marschik PB. Addressing sequelae of developmental regression associated with developmental disabilities: A systematic review of behavioral and educational intervention studies. Neurosci Biobehav Rev. 2019; 96: 56-71.

Autism spectrum disorderThe specificity of many environmental risks for autism spectrum disorder remains unknown and control of multiple confounders has been limited. Further understanding of the critical windows of neurodevelopmental vulnerability and investigating the fit of multiple hit and cumulative risk models are likely promising approaches in enhancing the understanding of role of environmental factors in the etiology of autism spectrum disorder.Bölte S, Girdler S, Marschik PB. The contribution of environmental exposure to the etiology of autism spectrum disorder. Cell Mol Life Sci. 2019; 76(7): 1275-1297.

Tracking general movementsWe are excited to launching a new project on clinical reasoning related to general movement assessment: supported by the Austrian Science Fund (FWF).