silver acetate catalyzed asymmetric 1,3-dipolar cycloadditions of imines and chiral acrylamides

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2005 Pyrrole derivatives R 0120 Silver Acetate Catalyzed Asymmetric 1,3-Dipolar Cycloadditions of Imines and Chiral Acrylamides. — Exclusive formation of chiral pyrrolidines (III) is achieved by reaction with acrylamides (II). With acrylamides (IV) and (VII) the cycloadducts are formed with moderate diastereoselectivities. — (NYERGES*, M.; BENDELL, D.; ARANY, A.; HIBBS, D. E.; COLES, S. J.; HURSTHOUSE, M. B.; GROUNDWATER, P. W.; METH-COHN, O.; Tetrahedron 61 (2005) 15, 3745-3753; Dep. Org. Chem. Technol., Tech. Univ. Budapest, H-1521 Budapest, Hung.; Eng.) — Klein 32- 118

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Page 1: Silver Acetate Catalyzed Asymmetric 1,3-Dipolar Cycloadditions of Imines and Chiral Acrylamides

2005

Pyrrole derivativesR 0120 Silver Acetate Catalyzed Asymmetric 1,3-Dipolar Cycloadditions of Imines and

Chiral Acrylamides. — Exclusive formation of chiral pyrrolidines (III) is achieved by reaction with acrylamides (II). With acrylamides (IV) and (VII) the cycloadducts are formed with moderate diastereoselectivities. — (NYERGES*, M.; BENDELL, D.; ARANY, A.; HIBBS, D. E.; COLES, S. J.; HURSTHOUSE, M. B.; GROUNDWATER, P. W.; METH-COHN, O.; Tetrahedron 61 (2005) 15, 3745-3753; Dep. Org. Chem. Technol., Tech. Univ. Budapest, H-1521 Budapest, Hung.; Eng.) — Klein

32- 118