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smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium christopher w. wilson, miao-hsueh chen, pao-tien chuang* cardiovascular…
smoothened joe vukina april 5, 2007 outline introduction and pathway normal function of smoothened and knockouts cancer: when smoothened goes wrong treatments? introduction…
1460 research article introduction primary cilia are filiform structures protruding from the plasma membrane that have been tied to a broad range of genetic disorders (singla…
pbio.1001239 1..15hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in drosophila shuang li1, yongbin chen1, qing shi1, tao yue1,
powerpoint presentation smoothened and the hedgehog (hh) pathway james (jay) lomax biol 445 3/19/13 what is smoothened? (a protein conserved in drosophila and humans) conservation…
smoothened (smo) in basal cell carcinoma thomas edwards biol 445 26 march 2009 hedgehog signaling pathway review active during embryonic development. highly conserved integral…
cellular cholesterol directly activates smoothened in hedgehog signalingin hedgehog signaling triggers hedgehog signaling d stimulation of hedgehog pathway activates smoothened
pnas200910712 9323..9328identification of select glucocorticoids as smoothened agonists: potential utility for regenerative medicine jiangbo wanga, jiuyi lua, michael c.
a novel synthetic smoothened antagonist transiently inhibits pancreatic adenocarcinoma xenografts in a mouse model martin f. strand1*, steven r. wilson3, jennifer l. dembinski1,…
smoothened variants explain the majority of drug resistance in basal cell carcinomalain the majority of drug resistance in basal cell carcinoma graphical abstract d functional
nihal almuraikhi,1 nuha almasoud,1 sarah binhamdan,1 ghaydaa younis,1 dalia ali,2 muthurangan manikandan,1 radhakrishnan vishnubalaji,3 muhammad atteya,1,4 abdulaziz siyal,1
genet61036 2049..2062copyright 2006 by the genetics society of america doi: 10.1534/genetics.106.061036 the contributions of protein kinase a and smoothened phosphorylation
smoothened determines β-arrestin–mediated removal of the g protein–coupled receptor gpr161 from the primary ciliumjcb: article jcb 861 the rockefeller university
4053development 124, 4053-4063 1997 printed in great britain © the company of biologists limited 1997 dev8441 smoothened-mediated hedgehog signalling is required for the…
himmelfarb health sciences library, the george washington university health sciences research commons anatomy and regenerative biology faculty publications anatomy and regenerative…
activation of smurf e3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover shoujun huang1 zhao zhang2 chunxia zhang3 xiangdong lv2…
826 research article introduction hedgehog hh is a secreted protein that patterns and specifies cell fate in several different tissues. in drosophila, response to hh is mediated…
article smoothened variants exp lain the majority of drug resistance in basal cell carcinoma graphical abstract highlights d functional smo mutations are detected in the…
this document is downloaded from dr‑ntu https:dr.ntu.edu.sg nanyang technological university, singapore. structure and function of the smoothened extracellular domain in vertebrate hedgehog…
hedgehog signal transduction by smoothened: pharmacologic evidence for a 2-step activation process rajat rohatgia,b,c,d,1, ljiljana milenkovica,b,c,1, ryan b. corcorana,b,c,…