sds cmg-cmg-1033(lb1)-lysis buffer 1 (component of … cmg-1033_… · · article number:...

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Safety data sheetaccording to 1907/2006/EC, Article 31

Printing date 14.08.2015 Revision: 14.08.2015Version number 13

41.1.0

* SECTION 1: Identification of the substance/mixture and of the company/undertaking

· 1.1 Product identifier

· Trade name: Lysis Buffer 1 (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

· Article number:CMG-1033(LB1)· 1.2 Relevant identified uses of the substance or mixture and uses advised against· Sector of Use- · Application of the substance / the mixtureProduct for analytical use

· 1.3 Details of the supplier of the safety data sheet· Manufacturer/Supplier:PerkinElmer chemagen Technologie GmbHArnold-Sommerfeld-Ring 252499 BAESWEILERDEUTSCHLANDe-mail: [email protected]

· Further information obtainable from:Abteilung Produktsicherheit· 1.4 Emergency telephone number:CHEMTREC (within U.S.) 800 424-9300CHEMTREC (from outside U.S) +1-703-672-3887

* SECTION 2: Hazards identification

· 2.1 Classification of the substance or mixture· Classification according to Regulation (EC) No 1272/2008

d~ GHS07

Acute Tox. 4 H302 Harmful if swallowed.

Acute Tox. 4 H312 Harmful in contact with skin.

Acute Tox. 4 H332 Harmful if inhaled.

· 2.2 Label elements· Labelling according to Regulation (EC) No 1272/2008The product is classified and labelled according to the CLP regulation.

· Hazard pictograms

d~GHS07

· Signal wordWarning

· Hazard-determining components of labelling:guanidinium thiocyanate

· Hazard statementsH302+H312+H332 Harmful if swallowed, in contact with skin or if inhaled.

· Precautionary statementsP261 Avoid breathing dust/fume/gas/mist/vapours/spray.P280 Wear protective gloves/protective clothing/eye protection/face protection.P322 Specific measures (see on this label).P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.P304+P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for

breathing.P501 Dispose of contents/container in accordance with local/regional/national/international

regulations.· Additional information:EUH032 Contact with acids liberates very toxic gas.

(Contd. on page 2) GB

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Trade name: Lysis Buffer 1 (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

(Contd. of page 1)

41.1.0

· 2.3 Other hazards· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.

SECTION 3: Composition/information on ingredients

· 3.2 Mixtures· Description:Mixture of substances listed below with nonhazardous additions.

· Dangerous components:CAS: 593-84-0EINECS: 209-812-1

guanidinium thiocyanated~ Acute Tox. 4, H302; Acute Tox. 4, H312; Acute Tox. 4, H332

60-80%

· Additional information: For the wording of the listed risk phrases refer to section 16.

SECTION 4: First aid measures

· 4.1 Description of first aid measures· General information:Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48hours after the accident.

· After inhalation:Supply fresh air. If required, provide artificial respiration. Keep patient warm. Consult doctor if symptomspersist.In case of unconsciousness place patient stably in side position for transportation.

· After skin contact:Generally the product does not irritate the skin.· After eye contact:Rinse opened eye for several minutes under running water.· After swallowing:Call for a doctor immediately.· 4.2 Most important symptoms and effects, both acute and delayedNo further relevant information available.· 4.3 Indication of any immediate medical attention and special treatment neededNo further relevant information available.

SECTION 5: Firefighting measures

· 5.1 Extinguishing media· Suitable extinguishing agents:CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.

· 5.2 Special hazards arising from the substance or mixture No further relevant information available.· 5.3 Advice for firefighters· Protective equipment:Mouth respiratory protective device.

SECTION 6: Accidental release measures

· 6.1 Personal precautions, protective equipment and emergency proceduresMount respiratory protective device.

· 6.2 Environmental precautions:Dilute with plenty of water.Do not allow to enter sewers/ surface or ground water.

· 6.3 Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).Dispose contaminated material as waste according to item 13.Ensure adequate ventilation.

· 6.4 Reference to other sectionsSee Section 7 for information on safe handling.


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(Contd. of page 2)

41.1.0

See Section 8 for information on personal protection equipment.See Section 13 for disposal information.

SECTION 7: Handling and storage

· 7.1 Precautions for safe handlingEnsure good ventilation/exhaustion at the workplace.Prevent formation of aerosols.

· Information about fire - and explosion protection:No special measures required.

· 7.2 Conditions for safe storage, including any incompatibilities· Storage:· Requirements to be met by storerooms and receptacles: No special requirements.· Information about storage in one common storage facility: Do not store together with acids.· Further information about storage conditions:Keep container tightly sealed.· 7.3 Specific end use(s)No further relevant information available.

SECTION 8: Exposure controls/personal protection

· Additional information about design of technical facilities: No further data; see item 7.

· 8.1 Control parameters· Ingredients with limit values that require monitoring at the workplace:The product does not contain any relevant quantities of materials with critical values that have to bemonitored at the workplace.

· Additional information: The lists valid during the making were used as basis.

· 8.2 Exposure controls· Personal protective equipment:· General protective and hygienic measures:Keep away from foodstuffs, beverages and feed.Wash hands before breaks and at the end of work.Avoid contact with the eyes and skin.

· Respiratory protection:In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposureuse self-contained respiratory protective device.

· Protection of hands:

S̀ Protective gloves

The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/the chemical mixture.Selection of the glove material on consideration of the penetration times, rates of diffusion and thedegradation

· Material of glovesThe selection of the suitable gloves does not only depend on the material, but also on further marks of qualityand varies from manufacturer to manufacturer. As the product is a preparation of several substances, theresistance of the glove material can not be calculated in advance and has therefore to be checked prior to theapplication.

· Penetration time of glove materialThe exact break through time has to be found out by the manufacturer of the protective gloves and has to beobserved.


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(Contd. of page 3)

41.1.0

· Eye protection:Goggles recommended during refilling

* SECTION 9: Physical and chemical properties

· 9.1 Information on basic physical and chemical properties· General Information· Appearance:

Form: FluidColour: Colourless

· Odour: Odourless· Odour threshold: Not determined.

· pH-value: Not determined.

· Change in conditionMelting point/Melting range: Undetermined.Boiling point/Boiling range: Undetermined.

· Flash point: Not applicable.

· Flammability (solid, gaseous): Not applicable.

· Ignition temperature:

Decomposition temperature: Not determined.

· Self-igniting: Product is not selfigniting.

· Danger of explosion: Product does not present an explosion hazard.

· Explosion limits:Lower: Not determined.Upper: Not determined.

· Vapour pressure at 20 °C: 23 hPa

· Density at 20 °C: 1.145 g/cm³· Relative density Not determined.· Vapour density Not determined.· Evaporation rate Not determined.

· Solubility in / Miscibility withwater: Fully miscible.

· Partition coefficient (n-octanol/water):Not determined.

· Viscosity:Dynamic: Not determined.Kinematic: Not determined.

· Solvent content:Organic solvents: 0.0 %Water: 35.0 %

Solids content: 65.0 %· 9.2 Other information No further relevant information available.

SECTION 10: Stability and reactivity

· 10.1 ReactivityNo further relevant information available.· 10.2 Chemical stability· Thermal decomposition / conditions to be avoided:No decomposition if used according to specifications.· 10.3 Possibility of hazardous reactionsNo dangerous reactions known.


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(Contd. of page 4)

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· 10.4 Conditions to avoidNo further relevant information available.· 10.5 Incompatible materials:No further relevant information available.· 10.6 Hazardous decomposition products:No dangerous decomposition products known.

* SECTION 11: Toxicological information

· 11.1 Information on toxicological effects· Acute toxicityHarmful if swallowed, in contact with skin or if inhaled.

· Primary irritant effect:· Skin corrosion/irritation Based on available data, the classification criteria are not met.· Serious eye damage/irritationBased on available data, the classification criteria are not met.· Respiratory or skin sensitisationBased on available data, the classification criteria are not met.· CMR effects (carcinogenity, mutagenicity and toxicity for reproduction)· Germ cell mutagenicityBased on available data, the classification criteria are not met.· CarcinogenicityBased on available data, the classification criteria are not met.· Reproductive toxicityBased on available data, the classification criteria are not met.· STOT-single exposureBased on available data, the classification criteria are not met.· STOT-repeated exposureBased on available data, the classification criteria are not met.· Aspiration hazardBased on available data, the classification criteria are not met.

SECTION 12: Ecological information

· 12.1 Toxicity· Aquatic toxicity:No further relevant information available.· 12.2 Persistence and degradabilityNo further relevant information available.· 12.3 Bioaccumulative potentialNo further relevant information available.· 12.4 Mobility in soilNo further relevant information available.· Additional ecological information:· General notes:Water hazard class 2 (German Regulation) (Self-assessment): hazardous for waterDo not allow product to reach ground water, water course or sewage system.Danger to drinking water if even small quantities leak into the ground.

· 12.5 Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.· 12.6 Other adverse effectsNo further relevant information available.

SECTION 13: Disposal considerations

· 13.1 Waste treatment methods· RecommendationMust not be disposed together with household garbage. Do not allow product to reach sewage system.

· Uncleaned packaging:· Recommendation:Disposal must be made according to official regulations.· Recommended cleansing agents:Water, if necessary together with cleansing agents.

SECTION 14: Transport information

· 14.1 UN-Number· ADR, IMDG, IATA UN2810


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(Contd. of page 5)

41.1.0

· 14.2 UN proper shipping name· ADR 2810 TOXIC LIQUID, ORGANIC, N.O.S. (guanidinium

thiocyanate)· IMDG, IATA TOXIC LIQUID, ORGANIC, N.O.S. (guanidinium

thiocyanate)

· 14.3 Transport hazard class(es)

· ADR, IMDG, IATA

dck|· Class 6.1 Toxic substances.· Label 6.1

· 14.4 Packing group· ADR, IMDG, IATA III

· 14.5 Environmental hazards:· Marine pollutant: No

· 14.6 Special precautions for user Warning: Toxic substances.· Danger code (Kemler): 60· EMS Number: F-A,S-A

· 14.7 Transport in bulk according to Annex II ofMarpol and the IBC Code Not applicable.

· Transport/Additional information:

· ADR· Limited quantities (LQ) 5L· Excepted quantities (EQ) Code: E1

Maximum net quantity per inner packaging: 30 mlMaximum net quantity per outer packaging: 1000 ml

· Transport category 2 · Tunnel restriction code E

· IMDG· Limited quantities (LQ) 5L· Excepted quantities (EQ) Code: E1


· UN "Model Regulation": UN2 8 10 , TOXIC L IQUID , ORGANIC, N.O .S .(guanidinium thiocyanate), 6.1, III

* SECTION 15: Regulatory information

· 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

· Directive 2012/18/EU· Named dangerous substances - ANNEX INone of the ingredients is listed.· 15.2 Chemical safety assessment:A Chemical Safety Assessment has not been carried out.

GB

(Contd. on page 7)

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(Contd. of page 6)

41.1.0

SECTION 16: Other informationThis information is based on our present knowledge. However, this shall not constitute a guarantee for anyspecific product features and shall not establish a legally valid contractual relationship.

· Relevant phrasesH302 Harmful if swallowed.H312 Harmful in contact with skin.H332 Harmful if inhaled.

· Department issuing MSDS:Department of Production· Contact:- · Abbreviations and acronyms:

ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsIATA: International Air Transport AssociationGHS: Globally Harmonised System of Classification and Labelling of ChemicalsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)PBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very BioaccumulativeAcute Tox. 4: Acute toxicity, Hazard Category 4

· * Data compared to the previous version altered. GB

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41.1.0



· Trade name: Binding Buffer 2 (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

· Article number:CMG-1033(BB2)· 1.2 Relevant identified uses of the substance or mixture and uses advised against· Sector of Use- · Application of the substance / the mixtureProduct for analytical use





d~ GHS02 flame

Flam. Liq. 3 H226 Flammable liquid and vapour.

d~ GHS07




d~GHS02

d~GHS07


· Hazard-determining components of labelling:sodium perchlorate

· Hazard statementsH226 Flammable liquid and vapour.H302 Harmful if swallowed.

· Precautionary statementsP210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking.P241 Use explosion-proof electrical/ventilating/lighting/equipment.P280 Wear protective gloves/protective clothing/eye protection/face protection.P240 Ground/bond container and receiving equipment.


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Trade name: Binding Buffer 2 (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

(Contd. of page 1)

41.1.0

P303+P361+P353 IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skinwith water/shower.

P501 Dispose of contents/container in accordance with local/regional/national/internationalregulations.

· 2.3 Other hazards· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.

* SECTION 3: Composition/information on ingredients



ethanol d~ Flam. Liq. 2, H225 50-70%

CAS: 7601-89-0EINECS: 231-511-9

sodium perchlorate d~ Ox. Sol. 1, H271;d~ Acute Tox. 4, H302 30-50%

CAS: 64-19-7EINECS: 200-580-7

acetic acid d~ Flam. Liq. 3, H226;d~ Skin Corr. 1A, H314 1-3%



· 4.1 Description of first aid measures· General information:Immediately remove any clothing soiled by the product.Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48hours after the accident.

· After inhalation: Supply fresh air; consult doctor in case of complaints.· After skin contact:Generally the product does not irritate the skin.· After eye contact:Rinse opened eye for several minutes under running water.· After swallowing:Call for a doctor immediately.· 4.2 Most important symptoms and effects, both acute and delayedNo further relevant information available.· 4.3 Indication of any immediate medical attention and special treatment neededNo further relevant information available.



· 5.2 Special hazards arising from the substance or mixture No further relevant information available.· 5.3 Advice for firefighters· Protective equipment:No special measures required.


· 6.1 Personal precautions, protective equipment and emergency proceduresWear protective equipment. Keep unprotected persons away.

· 6.2 Environmental precautions:Do not allow to enter sewers/ surface or ground water.· 6.3 Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).


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(Contd. of page 2)

41.1.0

Dispose contaminated material as waste according to item 13.Ensure adequate ventilation.

· 6.4 Reference to other sectionsSee Section 7 for information on safe handling.See Section 8 for information on personal protection equipment.See Section 13 for disposal information.



· Information about fire - and explosion protection:Keep ignition sources away - Do not smoke.

· 7.2 Conditions for safe storage, including any incompatibilities· Storage:· Requirements to be met by storerooms and receptacles: No special requirements.· Information about storage in one common storage facility: Not required.· Further information about storage conditions:Keep container tightly sealed.· 7.3 Specific end use(s)No further relevant information available.

* SECTION 8: Exposure controls/personal protection


· 8.1 Control parameters· Ingredients with limit values that require monitoring at the workplace:64-17-5 ethanolWEL Long-term value: 1920 mg/m³, 1000 ppm


· 8.2 Exposure controls· Personal protective equipment:· General protective and hygienic measures:Keep away from foodstuffs, beverages and feed.Immediately remove all soiled and contaminated clothingWash hands before breaks and at the end of work.


· Protection of hands:The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/the chemical mixture.Selection of the glove material on consideration of the penetration times, rates of diffusion and thedegradation




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(Contd. of page 3)

41.1.0




Form: FluidColour: According to product specification

· Odour: Characteristic· Odour threshold: Not determined.

· pH-value at 20 °C: 5.7

· Change in conditionMelting point/Melting range: Undetermined.Boiling point/Boiling range: 78 °C

· Flash point: > 55 °C


· Ignition temperature: 425 °C

· Decomposition temperature: Not determined.


· Danger of explosion: Not determined.

· Explosion limits:Lower: 3.5 Vol %Upper: 15.0 Vol %



· Solubility in / Miscibility withwater: Not miscible or difficult to mix.



· Solvent content:Organic solvents: 45 - 65 %Water: 2.8 %



· 10.1 ReactivityNo further relevant information available.· 10.2 Chemical stability· Thermal decomposition / conditions to be avoided:No decomposition if used according to specifications.· 10.3 Possibility of hazardous reactionsNo dangerous reactions known.


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(Contd. of page 4)

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· 10.4 Conditions to avoidNo further relevant information available.· 10.5 Incompatible materials:No further relevant information available.· 10.6 Hazardous decomposition products:No dangerous decomposition products known.


· 11.1 Information on toxicological effects· Acute toxicityHarmful if swallowed.



· 12.1 Toxicity· Aquatic toxicity:No further relevant information available.· 12.2 Persistence and degradabilityNo further relevant information available.· 12.3 Bioaccumulative potentialNo further relevant information available.· 12.4 Mobility in soilNo further relevant information available.· Additional ecological information:· General notes:Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for waterDo not allow undiluted product or large quantities of it to reach ground water, water course or sewagesystem.




· Uncleaned packaging:· Recommendation:Disposal must be made according to official regulations.




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(Contd. of page 5)

41.1.0

· 14.2 UN proper shipping name· ADR 1993 FLAMMABLE LIQUID, N.O.S. (ETHANOL (ETHYL

ALCOHOL))· IMDG FLAMMABLE LIQUID, N.O.S. (ETHANOL (ETHYL

ALCOHOL))· IATA FLAMMABLE LIQUID, N.O.S. (ETHANOL)


· ADR, IMDG, IATA

dcgx· Class 3 Flammable liquids.· Label 3



· 14.6 Special precautions for user Warning: Flammable liquids.· Danger code (Kemler): 30· EMS Number: F-E,S-E





· Transport category 3 · Tunnel restriction code D/E



· UN "Model Regulation": UN1993, FLAMMABLE LIQUID, N.O.S. (ETHANOL(ETHYL ALCOHOL)), 3, III



· Directive 2012/18/EU· Named dangerous substances - ANNEX INone of the ingredients is listed.· Seveso categoryP5c FLAMMABLE LIQUIDS· Qualifying quantity (tonnes) for the application of lower-tier requirements5,000 t· Qualifying quantity (tonnes) for the application of upper-tier requirements50,000 t


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(Contd. of page 6)

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· 15.2 Chemical safety assessment:A Chemical Safety Assessment has not been carried out.


· Relevant phrasesH225 Highly flammable liquid and vapour.H226 Flammable liquid and vapour.H271 May cause fire or explosion; strong oxidiser.H302 Harmful if swallowed.H314 Causes severe skin burns and eye damage.


ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsIATA: International Air Transport AssociationGHS: Globally Harmonised System of Classification and Labelling of ChemicalsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)PBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very BioaccumulativeFlam. Liq. 2: Flammable liquids, Hazard Category 2Flam. Liq. 3: Flammable liquids, Hazard Category 3Ox. Sol. 1: Oxidising Solids, Hazard Category 1Acute Tox. 4: Acute toxicity, Hazard Category 4Skin Corr. 1A: Skin corrosion/irritation, Hazard Category 1A


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41.1.0



· Trade name: Wash Buffer 3 (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

· Article number:CMG-1033(WB3)· 1.2 Relevant identified uses of the substance or mixture and uses advised against· Sector of Use- · Application of the substance / the mixtureProduct for analytical use





d~ GHS02 flame




d~GHS02

· Signal wordWarning· Hazard statementsH226 Flammable liquid and vapour.

· Precautionary statementsP210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking.P241 Use explosion-proof electrical/ventilating/lighting/equipment.P280 Wear protective gloves/protective clothing/eye protection/face protection.P240 Ground/bond container and receiving equipment.P303+P361+P353 IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin

with water/shower.P501 Dispose of contents/container in accordance with local/regional/national/international

regulations.· 2.3 Other hazards· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.

GB

(Contd. on page 2)

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Trade name: Wash Buffer 3 (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

(Contd. of page 1)

41.1.0





CAS: 7601-89-0EINECS: 231-511-9

sodium perchlorate d~ Ox. Sol. 1, H271;d~ Acute Tox. 4, H302 20-<25%



· 4.1 Description of first aid measures· After inhalation: Supply fresh air; consult doctor in case of complaints.· After skin contact:Generally the product does not irritate the skin.· After eye contact:Rinse opened eye for several minutes under running water.· After swallowing:If symptoms persist consult doctor.· 4.2 Most important symptoms and effects, both acute and delayedNo further relevant information available.· 4.3 Indication of any immediate medical attention and special treatment neededNo further relevant information available.





· 6.1 Personal precautions, protective equipment and emergency proceduresNot required.· 6.2 Environmental precautions:Dilute with plenty of water.Do not allow to enter sewers/ surface or ground water.

· 6.3 Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).



· 7.1 Precautions for safe handlingNo special precautions are necessary if used correctly.· Information about fire - and explosion protection:No special measures required.

· 7.2 Conditions for safe storage, including any incompatibilities· Storage:· Requirements to be met by storerooms and receptacles: No special requirements.· Information about storage in one common storage facility: Not required.


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(Contd. of page 2)

41.1.0

· Further information about storage conditions:None.· 7.3 Specific end use(s)No further relevant information available.





· 8.2 Exposure controls· Personal protective equipment:· General protective and hygienic measures:Wash hands before breaks and at the end of work.· Respiratory protection:Use suitable respiratory protective device in case of insufficient ventilation.· Protection of hands:The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/the chemical mixture.Selection of the glove material on consideration of the penetration times, rates of diffusion and thedegradation






Form: LiquidColour: Colourless



· Change in conditionMelting point/Melting range: Undetermined.Boiling point/Boiling range: > 34 °C

· Flash point: > 55 °C






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(Contd. of page 3)

41.1.0

· Danger of explosion: Not determined.







· Solvent content:Organic solvents: 25 - 45 %Water: 41.7 %

· 9.2 Other information No further relevant information available.


· 10.1 ReactivityNo further relevant information available.· 10.2 Chemical stability· Thermal decomposition / conditions to be avoided:No decomposition if used according to specifications.· 10.3 Possibility of hazardous reactionsNo dangerous reactions known.· 10.4 Conditions to avoidNo further relevant information available.· 10.5 Incompatible materials:No further relevant information available.· 10.6 Hazardous decomposition products:No dangerous decomposition products known.

SECTION 11: Toxicological information

· 11.1 Information on toxicological effects· Acute toxicity· Primary irritant effect:· Skin corrosion/irritation Based on available data, the classification criteria are not met.· Serious eye damage/irritationBased on available data, the classification criteria are not met.· Respiratory or skin sensitisationBased on available data, the classification criteria are not met.· CMR effects (carcinogenity, mutagenicity and toxicity for reproduction)· Germ cell mutagenicityBased on available data, the classification criteria are not met.· CarcinogenicityBased on available data, the classification criteria are not met.· Reproductive toxicityBased on available data, the classification criteria are not met.· STOT-single exposureBased on available data, the classification criteria are not met.· STOT-repeated exposureBased on available data, the classification criteria are not met.· Aspiration hazardBased on available data, the classification criteria are not met.


· 12.1 Toxicity· Aquatic toxicity:No further relevant information available.


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(Contd. of page 4)

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· 12.2 Persistence and degradabilityNo further relevant information available.· 12.3 Bioaccumulative potentialNo further relevant information available.· 12.4 Mobility in soilNo further relevant information available.· Additional ecological information:· General notes:Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for waterDo not allow undiluted product or large quantities of it to reach ground water, water course or sewagesystem.





* SECTION 14: Transport information


· 14.2 UN proper shipping name· ADR 1993 FLAMMABLE LIQUID, N.O.S. (ETHANOL (ETHYL

ALCOHOL))· IMDG FLAMMABLE LIQUID, N.O.S. (ETHANOL (ETHYL

ALCOHOL))· IATA FLAMMABLE LIQUID, N.O.S. (ETHANOL)


· ADR, IMDG, IATA




· 14.6 Special precautions for user Warning: Flammable liquids.· Danger code (Kemler): 30· EMS Number: F-E,S-E



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(Contd. of page 5)

41.1.0







· UN "Model Regulation": UN1993, FLAMMABLE LIQUID, N.O.S. (ETHANOL(ETHYL ALCOHOL)), 3, III





· Relevant phrasesH225 Highly flammable liquid and vapour.H271 May cause fire or explosion; strong oxidiser.H302 Harmful if swallowed.


ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsIATA: International Air Transport AssociationGHS: Globally Harmonised System of Classification and Labelling of ChemicalsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)PBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very BioaccumulativeFlam. Liq. 2: Flammable liquids, Hazard Category 2Flam. Liq. 3: Flammable liquids, Hazard Category 3Ox. Sol. 1: Oxidising Solids, Hazard Category 1Acute Tox. 4: Acute toxicity, Hazard Category 4


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41.1.0



· Trade name: Wash Buffer 4 (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

· Article number:CMG-1033(WB4)· 1.2 Relevant identified uses of the substance or mixture and uses advised against· Sector of Use- · Application of the substance / the mixtureProduct for analytical use





d~ GHS02 flame




d~GHS02

· Signal wordWarning· Hazard statementsH226 Flammable liquid and vapour.

· Precautionary statementsP210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking.P241 Use explosion-proof electrical/ventilating/lighting/equipment.P280 Wear protective gloves/protective clothing/eye protection/face protection.P240 Ground/bond container and receiving equipment.P303+P361+P353 IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin

with water/shower.P501 Dispose of contents/container in accordance with local/regional/national/international


GB

(Contd. on page 2)

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(Contd. of page 1)

41.1.0

* SECTION 3: Composition/information on ingredients




CAS: 7601-89-0EINECS: 231-511-9

sodium perchlorate d~ Ox. Sol. 1, H271;d~ Acute Tox. 4, H302 10-<20%



· 4.1 Description of first aid measures· General information:Immediately remove any clothing soiled by the product.· After inhalation: Supply fresh air; consult doctor in case of complaints.· After skin contact:Generally the product does not irritate the skin.· After eye contact:Rinse opened eye for several minutes under running water.· After swallowing:If symptoms persist consult doctor.· 4.2 Most important symptoms and effects, both acute and delayedNo further relevant information available.· 4.3 Indication of any immediate medical attention and special treatment neededNo further relevant information available.




* SECTION 6: Accidental release measures

· 6.1 Personal precautions, protective equipment and emergency proceduresWear protective equipment. Keep unprotected persons away.


· 6.3 Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).


* SECTION 7: Handling and storage

· 7.1 Precautions for safe handlingNo special precautions are necessary if used correctly.· Information about fire - and explosion protection:Keep ignition sources away - Do not smoke.Protect against electrostatic charges.


/7




(Contd. of page 2)

41.1.0






· 8.2 Exposure controls· Personal protective equipment:· General protective and hygienic measures:Immediately remove all soiled and contaminated clothingWash hands before breaks and at the end of work.

· Respiratory protection:Not required.· Protection of hands:The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/the chemical mixture.Selection of the glove material on consideration of the penetration times, rates of diffusion and thedegradation



· Eye protection:

R̀ Tightly sealed goggles



Form: FluidColour: Clear




/7




(Contd. of page 3)

41.1.0

· Change in conditionMelting point/Melting range: Undetermined.Boiling point/Boiling range: > 78 °C

· Flash point: 23 °C





· Danger of explosion: Product is not explosive. However, formation of explosive air/vapourmixtures are possible.







· Solvent content:Organic solvents: 60 - 80 %Water: 30 %

· 9.2 Other information No further relevant information available.




· 11.1 Information on toxicological effects· Acute toxicity· Primary irritant effect:· Skin corrosion/irritation Based on available data, the classification criteria are not met.· Serious eye damage/irritationBased on available data, the classification criteria are not met.· Respiratory or skin sensitisationBased on available data, the classification criteria are not met.


/7




(Contd. of page 4)

41.1.0

· CMR effects (carcinogenity, mutagenicity and toxicity for reproduction)· Germ cell mutagenicityBased on available data, the classification criteria are not met.· CarcinogenicityBased on available data, the classification criteria are not met.· Reproductive toxicityBased on available data, the classification criteria are not met.· STOT-single exposureBased on available data, the classification criteria are not met.· STOT-repeated exposureBased on available data, the classification criteria are not met.· Aspiration hazardBased on available data, the classification criteria are not met.


· 12.1 Toxicity· Aquatic toxicity:No further relevant information available.· 12.2 Persistence and degradabilityNo further relevant information available.· 12.3 Bioaccumulative potentialNo further relevant information available.· 12.4 Mobility in soilNo further relevant information available.· Additional ecological information:· General notes:Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for waterDo not allow undiluted product or large quantities of it to reach ground water, water course or sewagesystem.





* SECTION 14: Transport information


· 14.2 UN proper shipping name· ADR 1170 ETHANOL (ETHYL ALCOHOL) mixture· IMDG ETHANOL (ETHYL ALCOHOL) mixture· IATA ETHANOL mixture


· ADR, IMDG, IATA



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(Contd. of page 5)

41.1.0



· 14.6 Special precautions for user Warning: Flammable liquids.· Danger code (Kemler): 30· EMS Number: F-E,S-D








· UN "Model Regulation": UN1170, ETHANOL (ETHYL ALCOHOL) mixture, 3, III





· Relevant phrasesH225 Highly flammable liquid and vapour.H271 May cause fire or explosion; strong oxidiser.H302 Harmful if swallowed.


ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsIATA: International Air Transport AssociationGHS: Globally Harmonised System of Classification and Labelling of ChemicalsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)PBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very Bioaccumulative


/7




(Contd. of page 6)

41.1.0

Flam. Liq. 2: Flammable liquids, Hazard Category 2Flam. Liq. 3: Flammable liquids, Hazard Category 3Ox. Sol. 1: Oxidising Solids, Hazard Category 1Acute Tox. 4: Acute toxicity, Hazard Category 4


/5



41.1.0



· Trade name: Magnetic Beads, and Elution Buffer 5 (components of: chemagic Viral DNA/RNA Kitspecial, CMG-1033)

· Article number:CMG-1033(EB5)· 1.2 Relevant identified uses of the substance or mixture and uses advised against· Sector of Use- · Application of the substance / the mixtureProduct for analytical use




· 2.1 Classification of the substance or mixture· Classification according to Regulation (EC) No 1272/2008The product is not classified according to the CLP regulation.

· 2.2 Label elements· Labelling according to Regulation (EC) No 1272/2008Void· Hazard pictogramsVoid· Signal wordVoid· Hazard statementsVoid· 2.3 Other hazards· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.



· Dangerous components:Void· Additional information: For the wording of the listed risk phrases refer to section 16.


· 4.1 Description of first aid measures· General information:No special measures required.· After inhalation: Supply fresh air; consult doctor in case of complaints.· After skin contact:Generally the product does not irritate the skin.· After eye contact:Rinse opened eye for several minutes under running water.· After swallowing:If symptoms persist consult doctor.· 4.2 Most important symptoms and effects, both acute and delayedNo further relevant information available.


/5



Trade name: Magnetic Beads, and Elution Buffer 5 (components of: chemagic Viral DNA/RNA Kit special,CMG-1033)

(Contd. of page 1)

41.1.0

· 4.3 Indication of any immediate medical attention and special treatment neededNo further relevant information available.





· 6.1 Personal precautions, protective equipment and emergency proceduresNot required.· 6.2 Environmental precautions:Dilute with plenty of water.· 6.3 Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).



· 7.1 Precautions for safe handlingNo special measures required.· Information about fire - and explosion protection:No special measures required.

· 7.2 Conditions for safe storage, including any incompatibilities· Storage:· Requirements to be met by storerooms and receptacles: No special requirements.· Information about storage in one common storage facility: Not required.· Further information about storage conditions:None.· 7.3 Specific end use(s)No further relevant information available.





· 8.2 Exposure controls· Personal protective equipment:· General protective and hygienic measures:The usual precautionary measures are to be adhered to when handling chemicals.

· Respiratory protection:Not required.· Protection of hands:The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.


/5




(Contd. of page 2)

41.1.0

Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/the chemical mixture.Selection of the glove material on consideration of the penetration times, rates of diffusion and thedegradation









· Change in conditionMelting point/Melting range: Undetermined.Boiling point/Boiling range: 100 °C









· Density: Not determined.· Relative density Not determined.· Vapour density Not determined.· Evaporation rate Not determined.





/5




(Contd. of page 3)

41.1.0






· 11.1 Information on toxicological effects· Acute toxicity· Primary irritant effect:· Skin corrosion/irritation Based on available data, the classification criteria are not met.· Serious eye damage/irritationBased on available data, the classification criteria are not met.· Respiratory or skin sensitisationBased on available data, the classification criteria are not met.· CMR effects (carcinogenity, mutagenicity and toxicity for reproduction)· Germ cell mutagenicityBased on available data, the classification criteria are not met.· CarcinogenicityBased on available data, the classification criteria are not met.· Reproductive toxicityBased on available data, the classification criteria are not met.· STOT-single exposureBased on available data, the classification criteria are not met.· STOT-repeated exposureBased on available data, the classification criteria are not met.· Aspiration hazardBased on available data, the classification criteria are not met.


· 12.1 Toxicity· Aquatic toxicity:No further relevant information available.· 12.2 Persistence and degradabilityNo further relevant information available.· 12.3 Bioaccumulative potentialNo further relevant information available.· 12.4 Mobility in soilNo further relevant information available.· Additional ecological information:· General notes:Generally not hazardous for water· 12.5 Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.· 12.6 Other adverse effectsNo further relevant information available.


· 13.1 Waste treatment methods· RecommendationSmaller quantities can be disposed of with household waste.


/5




(Contd. of page 4)

41.1.0



· 14.1 UN-Number· ADR, ADN, IMDG, IATA not regulated

· 14.2 UN proper shipping name· ADR, ADN, IMDG, IATA not regulated


· ADR, ADN, IMDG, IATA· Class not regulated

· 14.4 Packing group· ADR, IMDG, IATA not regulated


· 14.6 Special precautions for user Not applicable.


· UN "Model Regulation": -






ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsIATA: International Air Transport AssociationGHS: Globally Harmonised System of Classification and Labelling of ChemicalsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)PBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very Bioaccumulative


/5



41.1.0



· Trade name: Poly(A) RNA (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

· Article number: CMG-1033(PA)· 1.2 Relevant identified uses of the substance or mixture and uses advised against· Sector of Use - · Application of the substance / the mixture Product for analytical use


· Further information obtainable from: Abteilung Produktsicherheit· 1.4 Emergency telephone number:CHEMTREC (within U.S.) 800 424-9300CHEMTREC (from outside U.S) +1-703-672-3887


· 2.1 Classification of the substance or mixture· Classification according to Regulation (EC) No 1272/2008The substance is not classified according to the CLP regulation.

· 2.2 Label elements· Labelling according to Regulation (EC) No 1272/2008 Void· Hazard pictograms Void· Signal word Void· Hazard statements Void· 2.3 Other hazards· Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.


· 3.1 Substances· CAS No. DescriptionPoly (A) RNA


· 4.1 Description of first aid measures· General information: No special measures required.· After inhalation: Supply fresh air; consult doctor in case of complaints.· After skin contact: Generally the product does not irritate the skin.· After eye contact: Rinse opened eye for several minutes under running water.· After swallowing: If symptoms persist consult doctor.· 4.2 Most important symptoms and effects, both acute and delayed No further relevant information available.· 4.3 Indication of any immediate medical attention and special treatment neededNo further relevant information available.

GB

(Contd. on page 2)

/5



Trade name: Poly(A) RNA (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

(Contd. of page 1)

41.1.0



· 5.2 Special hazards arising from the substance or mixture No further relevant information available.· 5.3 Advice for firefighters· Protective equipment: No special measures required.


· 6.1 Personal precautions, protective equipment and emergency procedures Not required.· 6.2 Environmental precautions: Do not allow to enter sewers/ surface or ground water.· 6.3 Methods and material for containment and cleaning up: Pick up mechanically.· 6.4 Reference to other sectionsSee Section 7 for information on safe handling.See Section 8 for information on personal protection equipment.See Section 13 for disposal information.


· 7.1 Precautions for safe handling No special measures required.· Information about fire - and explosion protection: No special measures required.

· 7.2 Conditions for safe storage, including any incompatibilities· Storage:· Requirements to be met by storerooms and receptacles: No special requirements.· Information about storage in one common storage facility: Not required.· Further information about storage conditions: None.· 7.3 Specific end use(s) No further relevant information available.



· 8.1 Control parameters· Ingredients with limit values that require monitoring at the workplace: Not required.· Additional information: The lists valid during the making were used as basis.

· 8.2 Exposure controls· Personal protective equipment:· General protective and hygienic measures:The usual precautionary measures are to be adhered to when handling chemicals.

· Respiratory protection: Not required.· Protection of hands:The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/the chemical mixture.Selection of the glove material on consideration of the penetration times, rates of diffusion and thedegradation

· Material of glovesThe selection of the suitable gloves does not only depend on the material, but also on further marks of qualityand varies from manufacturer to manufacturer.


/5




(Contd. of page 2)

41.1.0


· Eye protection: Not required.



Form: PowderColour: Transparent


· pH-value: Not applicable.



· Flammability (solid, gaseous): Product is not flammable.



· Self-igniting: Not determined.



· Vapour pressure: Not applicable.

· Density: Not determined.· Relative density Not determined.· Vapour density Not applicable.· Evaporation rate Not applicable.

· Solubility in / Miscibility withwater: Insoluble.

· Partition coefficient (n-octanol/water): Not determined.

· Viscosity:Dynamic: Not applicable.Kinematic: Not applicable.

· Solvent content:Organic solvents: 0.0 %VOC (EC) 0.00 %



· 10.1 Reactivity No further relevant information available.(Contd. on page 4)

GB

/5




(Contd. of page 3)

41.1.0

· 10.2 Chemical stability· Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.· 10.3 Possibility of hazardous reactions No dangerous reactions known.· 10.4 Conditions to avoid No further relevant information available.· 10.5 Incompatible materials: No further relevant information available.· 10.6 Hazardous decomposition products: No dangerous decomposition products known.


· 11.1 Information on toxicological effects· Acute toxicity· Primary irritant effect:· Skin corrosion/irritation Based on available data, the classification criteria are not met.· Serious eye damage/irritation Based on available data, the classification criteria are not met.· Respiratory or skin sensitisation Based on available data, the classification criteria are not met.· CMR effects (carcinogenity, mutagenicity and toxicity for reproduction)· Germ cell mutagenicity Based on available data, the classification criteria are not met.· Carcinogenicity Based on available data, the classification criteria are not met.· Reproductive toxicity Based on available data, the classification criteria are not met.· STOT-single exposure Based on available data, the classification criteria are not met.· STOT-repeated exposure Based on available data, the classification criteria are not met.· Aspiration hazard Based on available data, the classification criteria are not met.


· 12.1 Toxicity· Aquatic toxicity: No further relevant information available.· 12.2 Persistence and degradability No further relevant information available.· 12.3 Bioaccumulative potential No further relevant information available.· 12.4 Mobility in soil No further relevant information available.· Additional ecological information:· General notes:Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for waterDo not allow undiluted product or large quantities of it to reach ground water, water course or sewagesystem.

· 12.5 Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.· 12.6 Other adverse effects No further relevant information available.


· 13.1 Waste treatment methods· Recommendation Smaller quantities can be disposed of with household waste.

· Uncleaned packaging:· Recommendation: Disposal must be made according to official regulations.




/5




(Contd. of page 4)

41.1.0











· Directive 2012/18/EU· Named dangerous substances - ANNEX I Substance is not listed.· 15.2 Chemical safety assessment: A Chemical Safety Assessment has not been carried out.


· Department issuing MSDS: Department of Production· Contact: - · Abbreviations and acronyms:

ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsIATA: International Air Transport AssociationGHS: Globally Harmonised System of Classification and Labelling of ChemicalsCAS: Chemical Abstracts Service (division of the American Chemical Society)VOC: Volatile Organic Compounds (USA, EU)PBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very Bioaccumulative


/6



41.1.0



· Trade name: Proteinase K (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

· Article number:CMG-1033(PK)· CAS Number:39450-01-6

· EC number:254-457-8

· 1.2 Relevant identified uses of the substance or mixture and uses advised against· Sector of Use- · Application of the substance / the mixtureProduct for analytical use





d~ GHS08 health hazard

Resp. Sens. 1 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.

d~ GHS07

Skin Irrit. 2 H315 Causes skin irritation.

Eye Irrit. 2 H319 Causes serious eye irritation.

STOT SE 3 H335 May cause respiratory irritation.

· 2.2 Label elements· Labelling according to Regulation (EC) No 1272/2008The substance is classified and labelled according to the CLP regulation.


d~GHS07

d~GHS08

· Signal wordDanger

· Hazard-determining components of labelling:Proteinase, Tritirachium album serine

· Hazard statementsH315 Causes skin irritation.H319 Causes serious eye irritation.H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.


/6



Trade name: Proteinase K (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

(Contd. of page 1)

41.1.0

H335 May cause respiratory irritation.· Precautionary statementsP285 In case of inadequate ventilation wear respiratory protection.P261 Avoid breathing dust/fume/gas/mist/vapours/spray.P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if

present and easy to do. Continue rinsing.P321 Specific treatment (see on this label).P405 Store locked up.P501 Dispose of contents/container in accordance with local/regional/national/international



· 3.1 Substances· CAS No. Description39450-01-6 Proteinase, Tritirachium album serine

· Identification number(s)· EC number:254-457-8


· 4.1 Description of first aid measures· After inhalation: In case of unconsciousness place patient stably in side position for transportation.· After skin contact:Immediately wash with water and soap and rinse thoroughly.· After eye contact:Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.

· After swallowing:If symptoms persist consult doctor.· 4.2 Most important symptoms and effects, both acute and delayedNo further relevant information available.· 4.3 Indication of any immediate medical attention and special treatment neededNo further relevant information available.





· 6.1 Personal precautions, protective equipment and emergency proceduresNot required.· 6.2 Environmental precautions:No special measures required.· 6.3 Methods and material for containment and cleaning up:Dispose contaminated material as waste according to item 13.Ensure adequate ventilation.

· 6.4 Reference to other sectionsSee Section 7 for information on safe handling.See Section 8 for information on personal protection equipment.


/6




(Contd. of page 2)

41.1.0

See Section 13 for disposal information.


· 7.1 Precautions for safe handlingEnsure good ventilation/exhaustion at the workplace.Prevent formation of dust.





· 8.1 Control parameters· Ingredients with limit values that require monitoring at the workplace:Not required.· Additional information: The lists valid during the making were used as basis.

· 8.2 Exposure controls· Personal protective equipment:· General protective and hygienic measures:Keep away from foodstuffs, beverages and feed.Immediately remove all soiled and contaminated clothingWash hands before breaks and at the end of work.Avoid contact with the eyes and skin.





· Material of glovesThe selection of the suitable gloves does not only depend on the material, but also on further marks of qualityand varies from manufacturer to manufacturer.



/6




(Contd. of page 3)

41.1.0

· Eye protection:

R̀ Tightly sealed goggles



Form: PowderColour: White


· pH-value: Not applicable.



· Flammability (solid, gaseous): Product is not flammable.



· Self-igniting: Not determined.



· Vapour pressure: Not applicable.

· Density at 20 °C: 1.1 g/cm³· Relative density Not determined.· Vapour density Not applicable.· Evaporation rate Not applicable.

· Solubility in / Miscibility withwater: Soluble.


· Viscosity:Dynamic: Not applicable.Kinematic: Not applicable.

· Solvent content:Organic solvents: 0.0 %VOC (EC) 0.00 %


GB

(Contd. on page 5)

/6




(Contd. of page 4)

41.1.0




· 11.1 Information on toxicological effects· Acute toxicity· Primary irritant effect:· Skin corrosion/irritationCauses skin irritation.

· Serious eye damage/irritationCauses serious eye irritation.

· Respiratory or skin sensitisationMay cause allergy or asthma symptoms or breathing difficulties if inhaled.

· CMR effects (carcinogenity, mutagenicity and toxicity for reproduction)· Germ cell mutagenicityBased on available data, the classification criteria are not met.· CarcinogenicityBased on available data, the classification criteria are not met.· Reproductive toxicityBased on available data, the classification criteria are not met.· STOT-single exposureMay cause respiratory irritation.

· STOT-repeated exposureBased on available data, the classification criteria are not met.· Aspiration hazardBased on available data, the classification criteria are not met.


· 12.1 Toxicity· Aquatic toxicity:No further relevant information available.· 12.2 Persistence and degradabilityNo further relevant information available.· 12.3 Bioaccumulative potentialNo further relevant information available.· 12.4 Mobility in soilNo further relevant information available.· Additional ecological information:· General notes:Generally not hazardous for water· 12.5 Results of PBT and vPvB assessment· PBT: Not applicable.· vPvB: Not applicable.· 12.6 Other adverse effectsNo further relevant information available.



· Uncleaned packaging:· Recommendation:Disposal must be made according to official regulations.


/6




(Contd. of page 5)

41.1.0

· Recommended cleansing agents:Water, if necessary together with cleansing agents.













· Directive 2012/18/EU· Named dangerous substances - ANNEX ISubstance is not listed.· 15.2 Chemical safety assessment:A Chemical Safety Assessment has not been carried out.



ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)GHS: Globally Harmonised System of Classification and Labelling of ChemicalsEINECS: European Inventory of Existing Commercial Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)VOC: Volatile Organic Compounds (USA, EU)PBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very BioaccumulativeSkin Irrit. 2: Skin corrosion/irritation, Hazard Category 2Eye Irrit. 2: Serious eye damage/eye irritation, Hazard Category 2Resp. Sens. 1: Sensitisation - Respirat., Hazard Category 1STOT SE 3: Specific target organ toxicity - Single exposure, Hazard Category 3


/7



41.1.0



· Trade name: Poly(A) RNA Buffer (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

· Article number:CMG-1033(PAB)· 1.2 Relevant identified uses of the substance or mixture and uses advised against· Sector of Use- · Application of the substance / the mixtureProduct for analytical use





d~ GHS07




d~GHS07


· Hazard-determining components of labelling:guanidinium thiocyanate

· Hazard statementsH302 Harmful if swallowed.

· Precautionary statementsP264 Wash thoroughly after handling.P270 Do not eat, drink or smoke when using this product.P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.P330 Rinse mouth.P501 Dispose of contents/container in accordance with local/regional/national/international

regulations.· Additional information:EUH032 Contact with acids liberates very toxic gas.

· 2.3 Other hazards· Results of PBT and vPvB assessment· PBT: Not applicable.


/7



Trade name: Poly(A) RNA Buffer (component of: chemagic Viral DNA/RNA Kit special, CMG-1033)

(Contd. of page 1)

41.1.0

· vPvB: Not applicable.


· Description:Mixture of substances listed below with nonhazardous additions.


guanidinium thiocyanated~ Acute Tox. 4, H302; Acute Tox. 4, H312; Acute Tox. 4, H332

30-50%



· 4.1 Description of first aid measures· General information:Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48hours after the accident.

· After inhalation:Supply fresh air. If required, provide artificial respiration. Keep patient warm. Consult doctor if symptomspersist.In case of unconsciousness place patient stably in side position for transportation.

· After skin contact:Generally the product does not irritate the skin.· After eye contact:Rinse opened eye for several minutes under running water.· After swallowing:Call for a doctor immediately.· 4.2 Most important symptoms and effects, both acute and delayedNo further relevant information available.· 4.3 Indication of any immediate medical attention and special treatment neededNo further relevant information available.



· 5.2 Special hazards arising from the substance or mixture No further relevant information available.· 5.3 Advice for firefighters· Protective equipment:Mouth respiratory protective device.


· 6.1 Personal precautions, protective equipment and emergency proceduresMount respiratory protective device.


· 6.3 Methods and material for containment and cleaning up:Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).Dispose contaminated material as waste according to item 13.Ensure adequate ventilation.


GB

(Contd. on page 3)

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(Contd. of page 2)

41.1.0




· 7.2 Conditions for safe storage, including any incompatibilities· Storage:· Requirements to be met by storerooms and receptacles: No special requirements.· Information about storage in one common storage facility: Do not store together with acids.· Further information about storage conditions:Keep container tightly sealed.· 7.3 Specific end use(s)No further relevant information available.





· 8.2 Exposure controls· Personal protective equipment:· General protective and hygienic measures:Keep away from foodstuffs, beverages and feed.Wash hands before breaks and at the end of work.Avoid contact with the eyes and skin.







· Eye protection:Goggles recommended during refilling GB

(Contd. on page 4)

/7




(Contd. of page 3)

41.1.0






















· 10.1 ReactivityNo further relevant information available.· 10.2 Chemical stability· Thermal decomposition / conditions to be avoided:No decomposition if used according to specifications.· 10.3 Possibility of hazardous reactionsNo dangerous reactions known.· 10.4 Conditions to avoidNo further relevant information available.· 10.5 Incompatible materials:No further relevant information available.


/7




(Contd. of page 4)

41.1.0

· 10.6 Hazardous decomposition products:No dangerous decomposition products known.


· 11.1 Information on toxicological effects· Acute toxicityHarmful if swallowed.



· 12.1 Toxicity· Aquatic toxicity:No further relevant information available.· 12.2 Persistence and degradabilityNo further relevant information available.· 12.3 Bioaccumulative potentialNo further relevant information available.· 12.4 Mobility in soilNo further relevant information available.· Additional ecological information:· General notes:Water hazard class 2 (German Regulation) (Self-assessment): hazardous for waterDo not allow product to reach ground water, water course or sewage system.Danger to drinking water if even small quantities leak into the ground.








/7




(Contd. of page 5)

41.1.0

· 14.2 UN proper shipping name· ADR 2810 TOXIC LIQUID, ORGANIC, N.O.S. (guanidinium

thiocyanate)· IMDG, IATA TOXIC LIQUID, ORGANIC, N.O.S. (guanidinium

thiocyanate)


· ADR, IMDG, IATA

dck|· Class 6.1 Toxic substances.· Label 6.1



· 14.6 Special precautions for user Warning: Toxic substances.· Danger code (Kemler): 60· EMS Number: F-A,S-A





· Transport category 2 · Tunnel restriction code E



· UN "Model Regulation": UN2 8 10 , TOXIC L IQUID , ORGANIC, N.O .S .(guanidinium thiocyanate), 6.1, III




GB

(Contd. on page 7)

/7




(Contd. of page 6)

41.1.0


· Relevant phrasesH302 Harmful if swallowed.H312 Harmful in contact with skin.H332 Harmful if inhaled.


ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the InternationalCarriage of Dangerous Goods by Road)IMDG: International Maritime Code for Dangerous GoodsIATA: International Air Transport AssociationGHS: Globally Harmonised System of Classification and Labelling of ChemicalsEINECS: European Inventory of Existing Commercial Chemical SubstancesELINCS: European List of Notified Chemical SubstancesCAS: Chemical Abstracts Service (division of the American Chemical Society)PBT: Persistent, Bioaccumulative and ToxicvPvB: very Persistent and very BioaccumulativeAcute Tox. 4: Acute toxicity, Hazard Category 4


sds cmg-cmg-1033(lb1)-lysis buffer 1 (component of … cmg-1033_… · · article number:...

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