scripps 35th annual conference: clinical hematology & oncology brochure 2015

2015Clinical

Hematology & Oncology

s C r i p p s ’ 3 5 t H A n n u A l C O n f e r e n C e :

Saturday, February 14 – Tuesday, February 17, 2015 Hyatt Regency La Jolla at Aventine, San Diego, California

Course OverviewScripps’ 35th Annual Conference: Clinical Hematology and Oncology

2015, is designed for hematologists, oncologists, surgeons, radiation

oncologists, internists, and others desiring an update in these specialty

areas. The primary objective of this course is to bring together clini-

cians and leading experts in diverse areas of hematology and oncolo-

gy, affording them an intimate environment in which to discuss new

clinical developments and significant advances.

The first day of the program will focus on nonmalignant hematology

which will be followed by an update on hematologic malignancies

on the second day. New developments in oncology with a focus on

issues of current interest will be discussed on the third day, while the

final day will review breast cancer. All presenters will discuss their ap-

proaches to challenging but common clinical situations and there will

be ample time for participant interaction.

2015 Course Highlights• Conference presentations will be available via mobile app and conference website.

• Comprehensive presentations of the latest advances in cancer diagnosis and treatment with a strong patient care focus

• Oneofthefeweducationalconferencesaddressingnonmalignant hematology

• Renownedfacultyrepresentingthecountry’s leading institutions chosen for their expertise as well as teaching skills

• Meet the professor breakout sessions examining practical approaches to various controversies in therapies discussed in a highly dynamic, small-group setting

• AudienceResponseSystemusedfor instant feedbackand inter- active learning

• Multiplenetworkingandone-on-onediscussionopportunities

educational ObjectivesAfter attending this course, the attendee should be able to:

• Describe the clinical and molecular facets of pathogenesis, diagnostic approaches and therapeutic modalities available for various hematologic disorders.

• Selectandapplythechangingapproachestohematologicmalig- nancies, particularly as they relate to evidence-based standards of care, including innovations in diagnosis and treatment.

• Choosenewtherapeuticoptionsfor thetreatmentofanumber of common malignancies; understanding appropriate indications and contraindications to these therapeutic approaches.

• Integrate theevolvingapproaches tobreast cancer frombotha diagnostic, prognostic and therapeutic perspective.

• Apply practical expertise gained from the clinical situations discussed in the workshop sessions with an emphasis on data-based approaches to patients with common but serious hematologic conditions.

Cour se i n t roduc t ionAccreditation Physicians (MD, DO) Scripps Health is accredited by the Accreditation Council for ContinuingMedicalEducation(ACCME)toprovidecontinu-ing medical education for physicians.

Scripps Health designates this educational activity for a max-imum of 25.25 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Credit Breakdown:MainConference–25.25Saturday–7 Monday–7.5Sunday–7 Tuesday–3.75

Board of Registered Nurses (BRN)For the purpose of recertification, the American Nurses CredentialingCenteracceptsAMAPRACategory1Credits™ issuedbyorganizationsaccreditedbytheACCME.Forthepurposeofre-licensure,theCaliforniaBoardofRegisteredNursing accepts AMA PRA Category 1 Credits™. Moststates’BoardofRegisteredNursingacceptAMA PRA Cate-gory 1 Credit(s)™ as meeting continuing education require-ments for license renewal. Nurses should check with their stateboardregardinguseofCMEcredit

Physician Assistants (AAPA)AAPAacceptsCategoryIcreditfromAMACategoryICMEorganizationsaccreditedbyACCME.

DisclosureCommercial supportThis course is supported, in part, by educational grants from industry, in accordancewithACCMEaccreditationStandards for Commercial Support. At the time of print-ing, a complete listing of commercial supporters was not available. Appropriate acknowledgement will be given to all supporters at the time of the educational activity.

About scrippsscripps proton therapy Center in San Diego offers advanced radiation therapy for the treatment of cancerous tumors and certain non-cancerous conditions. One of only 15 operating proton treatment centers in the nationandtheonlyprotontherapycenterinSanDiego,thefacility features cancer-fighting technology that draws on decades of research and development in radiation therapy For more information about proton therapy at Scripps visit: www.scripps.org/services/cancer-care__proton-therapy.

scripps Cancer Care is committed to combating cancer. As one of only two Integrated Network CancerPrograms in California (as designated by the American College of Surgeons), we mobilize all the oncology resources of five hospital campuses, a broad network of cancer care specialists, affiliated physicians and renowned Scripps research professionals to help diagnose, treat and support patients facing cancer—in San Diego and be-yond. Working collaboratively toward cancer prevention, early detection and coordinated cancer treatment, our cancer care services are here for you when you need them. Our multidisciplinary approach ensures a compre-hensive treatment plan that pairs leading-edge technol-ogy with an experienced, respectful care staff who are sensitive to the whole person and a range of healing approaches. Patients benefit from a collective array of cancer-specific personnel and services, as well as vigorous dialog between researchers and clinicians that brings the latest medical knowledge bedside.

For more information about cancer care at Scripps visit: www.scripps.org/services/cancer-care.

http://www.scripps.org/services/cancer-care

Jeffrey Andrey, MD DivisionofHematology&Oncology BloodandMarrowTransplantation Scripps Clinic La Jolla, California

Carrie Costantini, MD HematologyandMedicalOncology AssociateDirector InternalMedicineResidencyProgram ScrippsMercyHospital SanDiego,California

Cynthia Crist, DNP, FNP-BC, AOCNP® Supervisor WoltmanFamilyInfusionCenter Scripps Cancer Center ScrippsMercyHospital,SanDiego SanDiego,California

Joan Kroener, MD Director,BreastProgram Scripps Clinic La Jolla, California

Course Director Michael Kosty, MD, FACP, FASCOMedicalDirector Scripps Green Cancer Center Director GraduateMedicalEducation Scripps Clinic/Scripps Green Hospital La Jolla, California

James Mason, MD Director,ScrippsClinicalResearch andContinuingMedicalEducation Director,ScrippsBloodand MarrowTransplantProgram Scripps Clinic La Jolla, California

Marie Shieh, MD DivisionofHematology&Oncology ScrippsMemorialHospital,LaJolla La Jolla, California

Darren Sigal, MD DivisionofHematology&Oncology Scripps Clinic La Jolla, California

James Sinclair, MD MedicalDirector,StevensDivision Scripps Cancer Center La Jolla, California

William Stanton, MD MedicalDirector ScrippsCancerCenterMercyHospital SanDiego,California

Melissa Torrey, MD DivisionofHematology&Oncology Scripps Clinic La Jolla, California

Sabina R. Wallach, MD, FRACP, FACP HematologyandMedicalOncology ChiefofStaffEmeritus ScrippsMemorialHospital,LaJolla La Jolla, California

Marin Xavier, MD HematologyandMedicalOncology MedicalDirector,CancerResearch AssociateDirector InternalMedicineResidencyProgram ScrippsMercyHospital SanDiego,California

Guest facultyDonald Abrams, MDProfessorofClinicalMedicine,University of California, San FranciscoIntegrativeOncology UCSF Osher Center for IntegrativeMedicine Chief of Hematology/Oncology, San Francisco General Hospital San Francisco, California

James Armitage, MD, FASCO Professor,InternalMedicine DivisionofHematology&Oncology UniversityofNebraskaMedicalCenter Omaha, Nebraska

Priscilla Kaliopi Brastianos, MD Director Central Nervous System MetastasisProgram AssistantPhysicianinMedicine MassachusettsGeneralHospital Cancer Center HarvardMedicalSchool Boston,Massachusetts

John Vernon Cox, DO, MBA, FACP, FASCO TexasOncologyMethodist Cancer Center EducationChair ASCOCancerEducationCommittee Editor-in-Chief Journal of Oncology Practice Dallas,Texas

George D. Demetri, MD, FASCO Director,CenterforSarcoma and Bone Oncology Senior Vice President for ExperimentalTherapeutics ProfessorofMedicine HarvardMedicalSchool Dana-FarberCancerInstitute Boston,Massachusetts

Terry Gernsheimer, MD ProfessorofMedicine DivisionofHematology University of Washington SchoolofMedicine MedicalTransfusionServices UniversityofWashingtonMedical Center and Seattle Cancer Care Alliance Seattle, Washington

Morie Gertz, MD, MACP Chair,DepartmentofMedicine MayoClinic Rochester,Minnesota

Stephen M. Hahn, MD Henry K. Pancoast Professor and Chair DepartmentofRadiationOncology PerelmanSchoolofMedicineatthe University of Pennsylvania Philadelphia, Pennsylvania

Arti Hurria, MD Director CancerandAgingResearchProgram Associate Professor, City of Hope Durate,California

J. Randolph Hecht, MD ProfessorofClinicalMedicine DavidGeffenSchoolofMedicineat UCLASchoolofMedicine CarolandSaulRosenzweigChair CancerTherapiesDevelopment Director,UCLAGastrointestinal Oncology Program Los Angeles, California

Maha Hussain, MD, FACP, FASCO CisMaiselProfessorofOncology ProfessorofMedicineandUrology AssociateDirectorforClinicalResearch Co-Leader, Prostate Cancer Program UniversityofMichigan Comprehensive Cancer Center AnnArbor,Michigan

Maxine S. Jochelson, MD DirectorofRadiology,Breast andImagingCenter MemorialSloanKettering Cancer Center New York, New York

Hagop Kantarjian, MD ProfessorofMedicine Chairman,DepartmentofLeukemia MDAndersonCancerCenter University of Texas Houston, Texas

Raj Kasthuri, MD Director,UNCHHTCenter ofExcellence Associate Professor DivisionofHematology/OncologyUNC Chapel Hill Chapel Hill, North Carolina

John Kelton, MD, FRCPC Professor PathologyandMolecularMedicine Dean&Vice-President Faculty of Health Sciences ProfessorofMedicine McMasterUniversity Hamilton, Ontario

Stephanie Lee, MD, MPH Director,Long-TermFollow-UpProgram,Seattle Cancer Care Alliance/Fred Hutchinson Cancer ResearchCenter ProfessorofMedicalOncology University of Washington SchoolofMedicine Seattle, Washington

Alice Ma, MD AssociateProfessorofMedicine DivisionofHematology/Oncology University of North Carolina SchoolofMedicine Chapel Hill, North Carolina

Robert Stephen Makar, MD, PhD Assistant in Pathology AssociateDirector Blood Transfusion Service MassachusettsGeneralHospital Assistant Professor HarvardMedicalSchool Boston,Massachusetts

Stephan Moll, MD ProfessorofMedicine DivisionofHematology/Oncology University of North Carolina SchoolofMedicine Chapel Hill, North Carolina

Susan O’Brien, MD Ashbel Smith Professor DepartmentofLeukemia DivisionofCancerMedicine TheUniversityofTexasMDAnderson Cancer Center Houston, Texas

Thomas Ortel, MD, PhD ProfessorofMedicine&Pathology Chief,DivisionofHematology Director AnticoagulationManagementService Director DukeClinicalCoagulationand PlateletImmunologyLaboratories DukeUniversitySchoolofMedicine Durham,NorthCarolina

Edith A. Perez, MD DeputyDirectoratLarge MayoClinicCancerCenter Group Vice Chair Alliance for Clinical Trials in Oncology SereneM.andFrancesC.Durling ProfessorofMedicine Director,BreastCancer Translational Genomics Program Hematology/Oncology and Cancer Biology MayoClinic Jacksonville, Florida

Faculty Disclosure: In accordance with the ACCME Standards for Commercial Support, course directors, planning committees, faculty and all oth-ers in control of the educational content of the CME activity must disclose all relevant financial relation-ships with any commercial interest that they or their spouse/partner may have had within the past 12 months. If an individual refuses to disclose relevant financial relationships, they will be disqualified from being a part of the planning and implementation of this CME activity. Employees of a commercial inter-est with business lines or products relating to the content of the CME activity will not participate in the planning or any accredited portion of the con-ference. Disclosure will be made to all participants at the conference location, prior to the educational activity commencement.

David L. Porter, MD Jodi Fisher Horowitz Professor in LeukemiaCareExcellence Director BloodandMarrowTransplantation Hospital of the University of Pennsylvania and Abramson Cancer Center Philadelphia, Pennsylvania

Christy Russell, MD AssociateProfessorofMedicine University of Southern California Los Angeles, California

Joshua D. Schiffman, MD Associate Professor, Pediatrics Adjunct Associate Professor Oncological Sciences University of Utah Salt Lake City, Utah

H. Irene Su, MD, MSCE Assistant Professor DivisionofReproductive EndocrinologyandInfertility UniversityofCalifornia,SanDiego La Jolla, California

Theodore (Ted) E. Warkentin, MD Professor,DepartmentofPathologyandMolecularMedicine andDepartmentofMedicine McMasterUniversity Hamilton, Ontario, Canada

Michael E. Williams, MD Chief HematologicMalignanciesSection ByrdS.LeavellProfessorofMedicine Hematology and Oncology UniversityofVirginiaSchoolofMedicine Charlottesville, Virginia

Anas Younes, MD Chief, Lymphoma Service MemorialSloan-Kettering Cancer Center New York, New York

Course planning Committee

facu l t y

saturday, february 14, 2015NoNmaligNaNt Hematology

7 a.m. Registration, Breakfast & View Exhibits

7:50 a.m. Welcome and introduction Michael P. Kosty, MD

Morning Moderator: William Stanton, MD

8 a.m. Challenging Situations in transfusion medicine: indications for Red Cell, Platelet and FFP transfusion Robert Makar, MD, PhD

8:45 a.m. Heparin induced thrombocytopenia - 2015 John Kelton, MD

9:30 a.m. Break & View Exhibits

10 a.m. acquired von Willebrand Syndrome and Cardiovascular Disease Ted Warkentin, MD

10:45 a.m. Venous thromboembolism: Special management issues Thomas Ortel, MD

11:30 a.m. the Patient Who Bleeds after Surgery - What the Hematologist Needs to think about Terry Gernsheimer, MD

12:15 p.m. Lunch

Afternoon Moderator: Marin Xavier, MD

1:15 p.m. less Common Clots Stephan Moll, MD

2 p.m. iron Disorders - iron Deficiency and Hemochromatosis Raj Kasthuri, MD

2:45 p.m. mild Cytopenias: How much Workup to do? Alice Ma, MD

3:30 p.m. Break & View Exhibits

4 p.m. meet tHe PRoFeSSoR

1. Patients with thrombocytopenia John Kelton, MD

2. Consumptive Coagulopathies Ted Warkentin, MD

3. Vte Update Stephan Moll, MD

4. Hemolytic anemias Alice Ma, MD

5. a Practical approach to anemia Raj Kasthuri, MD

5 p.m. Adjourn

5 – Welcome & Networking Reception 6:30 p.m.

sunday, february 15, 2015maligNaNt Hematology

7 a.m. Breakfast & View Exhibits

Morning Moderator: Alan Saven, MD

8 a.m. molecular monitoring and mutations in Chronic myeloid leukemia: How to get the most out of your tyrosine Kinase inhibitor Hagop Kantarjian, MD

8:45 a.m. Surveillance imaging for lymphoma: Pros and Cons James Armitage, MD


10 a.m. incorporating New agents into the treatment of Cll Susan O’Brien, MD

10:45 a.m. mantle Cell lymphoma: Biology, Clinical Presentation, and therapeutic approaches Michael Williams, MD

SCHWaRtz leCtURe 11:30 a.m. genetically engineered t-cells and Beyond: immune modulation in Cll David Porter, MD

12:15 p.m. Lunch

Afternoon Moderator: Jeffrey Andrey, MD

1:15 p.m. is there Still a Role for High-Dose melphalan in the treatment of multiple myeloma? Morie Gertz , MD

2 p.m. Survivorship issues Post transplant Stephanie Lee, MD

2:45 p.m. advances in the treatment of advanced Stage Hodgkin Disease Anas Younes, MD


4 p.m. meet tHe PRoFeSSoR (repeat from Saturday)

1. Patients with thrombocytopenia John Kelton, MD

2. Consumptive Coagulopathies Ted Warkentin, MD

3. Vte Update Stephan Moll, MD

4. Hemolytic anemias Alice Ma, MD

5. a Practical approach to anemia Raj Kasthuri, MD

5 p.m. Adjourn

p rogram

Monday, february 16, 2015UPDateS iN oNCology

7 a.m. Breakfast & View Exhibits

Morning Moderator: Carrie Costantini, MD

8 a.m. Proton therapy of Solid tumors - Point: Counterpoint Stephen Hahn, MD

8:45 a.m. optimal management of CNS metastasis Priscilla Brastianos, MD


loNgmiRe leCtURe 10 a.m. Perioperative management of locally advanced esophagogastric Cancer J. Randolph Hecht, MD

10:45 a.m. Sarcomas: From Chemotherapy to targeted therapy George Demetri, MD

11:30 a.m. Hereditary Cancer Syndromes Joshua Schiffman, MD

12:15 p.m. Lunch

Afternoon Moderator: Sabina R. Wallach, MD , FRACP, FACP

1:15 p.m. genomic Profiling of tumors - What is the standard of care? TBD

2 p.m. is there Currently an established Role for the Use of Predictive or Prognostic molecular markers in the management of Colorectal Cancer Darren Sigal, MD

2:45 p.m. management of early Recurrent or advanced Prostate Cancer Maha Hussain, MD


4 p.m. the Rational Use of Supplements in Cancer Care Donald Abrams, MD

4:45 p.m. Community oncology in an era of Payment Reform John Cox, DO

5:30 p.m. Adjourn

tuesday, february 17, 2015BReaSt CaNCeR UPDate

7 a.m. Breakfast

Morning Moderator: Joan Kroener, MD

7:30 a.m. Fertility Preservation in Breast Cancer Patients Irene Su, MD

8:15 a.m. HeR-2 directed therapy in Breast Cancer Edith Perez, MD

9 a.m. Break

9:15 a.m. imaging in Breast Cancer Patients - What’s appropriate? Maxine Jochelson, MD

10 a.m. adjuvant therapy for older Women with early-Stage Breast Cancer Arti Hurria, MD

10:45 a.m. optimal management of the Pre- menopausal Patient with estrogen Receptor–Positive Breast Cancer Christy Russell, MD

11:30 a.m. Final Adjournment

3777LaJollaVillageDrive

SanDiego,CA92122

Reservations:888-421-1442

HotelDirect:858-552-1234

Web: hyattregencylajolla.com

rates & reservationsWe have obtained a special rate starting at $239 per night(plustax).Thisrateincludes:

• Discounteddayandovernightself-parkingfor$15

• Complimentaryhighspeedwiredinternetinguestroom

Hyatt regency la Jolla at Aventine

Con fe rence loca t ion & Ho te l i n fo rma t ion

Download the scripps CMe AppAll conference information including a detailed agenda, faculty listing, faculty disclosures, industry support, at-tendeelist,andcoursematerialscanbefoundonthefreeScrippsCMEconferenceappforiPhone,iPad,Android,and BlackBerry. To download the app on your smart phone or other device visit the appropriate app store and searchScrippsCME(mustbeoneword).Theappisfreeofchargeandwillbecontinuouslyupdatedduringandafter the course.

To access the site using your cell phone or computer’s web browser:http://www.grupio.com/ScrippsCME

Make your reservations early! A block of rooms is be-

ingheldforScrippsuntilMonday,January12,2015.After

January 12, 2015 reservations will be accepted on a space

and rate availability basis only. Please make your own res-

ervations and be sure to mention the Scripps conference to

receive the reduced rate and conference amenities.

Please note: Attendees who book their room through

an online, third-party service (Hotels.com©, Expedia.

com©, Priceline.com©, etc.) are not eligible to receive

the ameni ties listed under the rate information.

http://hyattregencylajolla.com

http://www.grupio.com/ScrippsCME

F i r s t n a m e , m i , L a s t n a m e D e g r e e ( m D , D O , P h D , r n , e t c )

B a D g e n a m e ( i F D i F F e r e n t F r O m a B O v e ) a F F i L i a t i O n / h O s P i t a L / c O m P a n y s P e c i a L t y

D i r e c t m a i L i n g a D D r e s s

c i t y / s t a t e / z i P c O D e

D i r e c t t e L e P h O n e F a x

e m a i L Ass i s tAnt e -MA i l

Ass i s tAnt nAMe Ass i s tAnt D i reCt t e l e pHOne

Pa y m e n t m e t h o d Check, Please make checks payable to Scripps (in U.S. dollars only).

If paying by credit card, please fill out the information below. visa mastercard amex Discover

c r e D i t c a r D n u m B e r e x P i r a t i O n D a t e s e c u r i t y c O D e O n c a r D (required)

n a m e O n c a r D s i g n a t u r e

B i L L i n g a D D r e s s i F D i F F e r e n t F r O m a B O v e

conference feesIncluded with full conference registration: Course tuition, access to conference materials(viamobileappandconferencewebsite),internetinmeetingspace, breakfasts,breaks,lunchesandtheWelcomeReceptionNot Included:Printedcoursesyllabus(presentationsavailableviamobileappand conferencewebsite),travelcosts,parking,lodginganddinners

Full Conference Thru Jan 2 Jan 3 - Feb 6 On-site

after Feb 6

Physicians $600 $650 $675

Nurses/Nurse Practitioners/Physician Assistants/ $425 $475 $500 Pharmacists/Allied Health Professionals

Fellows and Residents $150 $200 $225

Day Rate: (circle days) Saturday Sunday Monday Tuesday

Thru Jan 2 Jan 3 - Feb 6 On-site after Feb 6

Day Rate $250 $300 $325

saturday welcome reception IwouldliketoattendtheWelcomeReception(cost included in my registration) $0 IwouldliketopurchaseadditionalWelcomeReceptionticketsat$15/each # tickets

conference course materials Access to Conference App, which includes audio recordings and presentations (thisisincludedwiththecostofmainanddayconferenceregistrationrates) $199

Printed Course Syllabus Only - Conference presentations will be available via mobile app and conference website. You are able to download, save and/or print these presentations. Ifyouwouldlikeaprintedversionyoumustpre-orderithere(limitedsupplyavailable). $40

WouldyouliketoreceivetheScrippsConferenceServices&CMEEmailNewsletter? Yes No

By completing this registration form and returning it to Scripps you are acknowledging compliance with all attendance policies.

please pr int c lear ly. Should we have any conference communicat ions or updates please provide your direct contact information.

Ways to registerOnline scripps.org/hemonccme

Fax 858-652-5565

Mail ScrippsConferenceServices&CME Clinical HemOnc 11025NorthTorreyPinesRd. Suite200,Maildrop:SCRC200 LaJolla,California92037

Attendance policiesregistration confirmationA confirmation letter will be e-mailed or mailed to you upon receipt of the con-ference registration form and payment. Ifyou have not received it within two weeks, please contact the Scripps Conference Ser-vices&CMEoffice.

attendee cancellation, substitution, refundThe course tuition is refundable, minus a $100processing fee ($25 for FellowsandResidents), if your cancellation is receivedinwritingnolaterthanFriday,February6,2015. Attendee substitutions are allowed, but notification must be made in writing by February6,2015.Afterthisdate,undernocircumstances will refunds, credits, or sub-stitutions be granted. No refunds or credits will be given to “no shows.”

scripps conference modification or cancellationScripps reserves the right to modify the course’s schedule or program as necessary. Scripps also reserves the right to cancel this conference, in which case a full refund of the registration fee will be provided. We areunabletorefundanytravelcosts(flight, hotel,etc.)inthecaseofScrippscancellation.

p l e A s e i n D i C At e A n y s p e C i A l n e e D s ( i n C l u D i n G D i e tA r y r e s t r i C t i O n s ) Special requests will be considered and accommodated in full compliance with the Americans with Disabilities Act (ADA).

Clinical Hematology & Oncology

f ees & reg i s t ra t i on – february 14 - february 17, 2015

9

f o l l o w u s ! www.facebook.com/ScrippsCME www.twitter.com/scrippshealth www.youtube.com/scrippshealth

2015Clinical




Scripps Conference Services & CME 11025 N. Torrey Pines Rd., Suite 200 La Jolla, California 92037www.scripps.org/conferenceservices

2015Clinical




target Audience• Hematologists/ Oncologists

• MedicalOncologists

• Surgeons

• RadiationOncologists

• Internists

• NursePractitioners

• PhysicianAssistants

• Nursesandothers desiring an update in these specialty areas

Scripps Conference Services & CME

Phone:858-652-5400

Online: www.scripps.org/conferenceservices

mailto: [email protected]