royal medical and chirurgical society. june 27,3848.—j. m. arnott, esq., f.r.s., president

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102 On the Pathology of Asphyxia, and its Removal by Transfusing the Arterial Blood of Animals. By ROBERT BRANDON, Esq., London. ASPFIYYIA is the cessation of the specific vitality of the brain through the partial or total cessation of the heart’s action, and death, from whatever cause produced, is only asphyxia. In asphyxia, there is a want of arterial blood, and the most obvious cure is, the supply of this by means well known to surgeons of former times. Arterial blood was procured from animals, and a communication being established between the artery of the animal and that of the patient, a sufficient quantity was allowed to flow through an elastic tube, until the heart’s action was restored. It has been objected, that there is a difference in the size of the blood globules of animals, as compared with those of the human subject; but surely this can be of no consequence, since the arteries and veins are large enough to allow of the passage of globules twice the size of those contained in the blood of animals. I propose the use of this operation in all cases of approaching death; but we should not hesitate to operate, even when the heart’s action has ceased. The brain dies before the heart, and there is no doubt that life may be recalled, if there be but the minimum amount of pulsation in the heart. But we may even go beyond this, and assert, without fear of contradiction, that the heart’s action may be, and has often been, restored, after it had en- tirely ceased. Again, the heart’s action has sometimes only apparently ceased, only that the pulsations are not visible through the thorax. If you poison a rat, and ’open the chest after all action of the vital functions has ceased, you may witness the truth of what is here insisted on. Pure oxygen gas has been used with success, to restore the heart’s action after it has quite ceased; and so has galvanism, passed through the base of the brain and upper part of the spinal marrow; and so has brandy; and in the case of infants born asphyxiated, artificial respiration and the hot bath are often used to recal the play of the vital functions. In asphyxia, the hot bath should be used at a high temperature, in order to produce the greatest effect in the least time, since the arterialization of the blood, by means of the skin, cannot take place to the full extent when the patient is in the bath. On Suffocation by Drowning, and from Paralysis of the Muscles of the Larynx. By S. GOWER, Esq., Surgeon, Hampstead. IN the instructions of the Humane Society, for the recovery of persons apparently drowned, the popular remedy of hold- ing the drowned person up by the heels is justly condemned. It was no doubt popularly expected, that some pailfuls of water would run out at the mouth and nose in this posture. But it is desirable that, amongst other means used, the mouth should be placed, not retained, in a depending position, to allow of any fluid escaping, by the force of gravitation, from the larynx. A case in point once occurred to me, which made an indelible impression on my mind. It was that of a child, not drowned, but with the muscles which assist in deglutition partially paralyzed. Some castor oil had been given, and, I think, a small dose of calomel, but it was doubtful whether they had passed the pharynx, and whether the epiglottis had proved treacherous. There was difficult respiration, and a guggling sound in breathing. I had the child placed on its side, or rather on its stomach, when some of the oil and a quantity of mucus flowed from the mouth and throat, and the respiration was immediately and entirely relieved. The child died, but died less distressed and more easily than it would otherwise have done, presenting also a much less painful spec- tacle of apparent suffering. An attention to this circum- stance, in cases of apparent drowning, seems to be one of those things, the neglect of which would be an oversight. Medical Societies. ROYAL MEDICAL AND CHIRURGICAL SOCIETY. JUNE 27,3848.—J. M. ARNOTT, ESQ., F.R.S., PRESIDENT. ON THE UTILITY OF TRISNITRATE OF BISMUTH IN THE DIARRHŒA ACCOMPANYING PHTHISIS. By THEOPHILUS THOMPSON, M.D., F.R.S., Physician to the Hospital for Consumption and Diseases of the Chest. THE author considers the trisnitrate of bismuth to surpass in efficacy and safety our most approved remedies for this com- plaint. He has taken every opportunity, during the last twelve months, of testing its powers, and has preserved notes of twenty-one of the cases in which it was administered. Of these, eighteen were phthisis in various stages of progress, and three, bronchitis. In fifteen of the patients the diarrhaea was entirely removed; in four, transient benefit was experienced, and the remedy proved useless only in two instances. The dose administered was about five grains three or four times daily, usually combined with a little magnesia and gum arabic. Dr. Thompson has referred to various authors who have written respecting the properties of bismuth, without being able to collect from them any evidence of its powers in the phthisical variety of diarrhoea, but he entertains a strong conviction of its peculiar appropriateness to this affection, and has obtained important confirmation of his experience in a recent communication from Dr. Lombard, of Geneva. A PLAN OF TREATING OVARIAN DROPSY BY THE ULCERATIVE OPENING OF THE CYST AFTER ITS PERMANENT ADHESION TO THE WALLS OF THE ABDOMEN. By EDWARD JOHN TILT, M.D. The author was led to attempt this mode of cure by ob. serving the process of Nature in some spontaneous and radical cures of ovarian dropsy. His first object is, to establish solid adhesion between the peritonaeal covering of the cyst and the peritonseal lining of the abdominal parietes. His second ob- ject is, to make the smallest possible opening into the cyst, so that it may not be suddenly emptied, but remain always full, and be only relieved per stilicidium of the overplus of liquid distending its cavity, while it gradually contracts. To attain both these objects he adopts the plan which has often been successful in effecting the adhesion of hydatid cysts of the liver to the abdominal walls. It consists in the application of Vienna paste to the appropriate part of the abdomen. He relates one case in which a radical cure of an ovarian cyst was effected by this means. A lady, who had always enjoyed good health, ceased men- struating at forty years of age. Soon afterwards, having been exposed to cold, she was seized with violent pain in the left iliac fossa, followed by shivering and high fever. When these symp. toms were relieved, a tumour of the size of an orange was felt in the situation of the left ovary. This tumour gradually increased, and in a short space of time the patient had the ap. pearance of being advanced nine months in pregnancy. Vienna paste was applied to the pit of the stomach; an eschar was produced, and fell off, and afterwards a small opening was formed by ulceration, through which an albuminous, ropy fluid escaped. The abdomen was supported by moderate pressure. In a few weeks the discharge became purulent and offensive. Tepid water was then injected into the cyst daily for some months; the cyst gradually contracting, so that at length it would receive only an ounce of water. In about a year the patient was in effect well, although for several years a fistulous opening remained at the pit of the stomach. In the course of the case the cyst formed a communication with one of the intestines, and for several days the patient passed purulent stools, while, during that time, no pus escaped from the external wound. CASE OF HYDATID DISEASE OF THE LIVER CURED BY OPERATION. By GEORGE OWEN REES, M.D., F.R.S., Assistant-physician to Guy’s Hospital, and Principal Medical Officer to the Pen- tonville Prison. The case is detailed at some length. The patient was a man aged thirty-one years; admitted into Guy’s Hospital on the 13th of October, 1847. Examination of his abdomen detected a distinct tumour occupying the right hypochondriac and epigastric regions. Fluctuation could be felt in it. On the 4th of December the tumour was tapped by Mr. Hilton, with a trocar and canula not larger than an ordinary exploring needle, straps of plaster having previously been passed round the body, so as to fix the tumour in position, and to exert pressure upwards. Thirty-eight ounces of clear fluid were re- moved. The wound quickly closed. On the 7th of January, the tapping was repeated with the same instrument, and with the same precautions, as before. On this occasion pus of a very offensive odour escaped, and only ten ounces were ob- tained, owing to the canula becoming obstructed. On the 9th of January the tumour was tapped a third time with a full- sized trocar and canula, an elastic gum-tube being passed through the canula. Twenty-four ounces of foetid pus escaped, with membranous flakes, and partially-destroyed hydatids. The opening was maintained, and feetid pus, with, occasionally hydatids, continued to be discharged (the capacity of the sac at the same time diminishing) till the commencement of April. On the llth of April the discharging orifice had closed, and

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102

On the Pathology of Asphyxia, and its Removal by Transfusingthe Arterial Blood of Animals.

By ROBERT BRANDON, Esq., London. ASPFIYYIA is the cessation of the specific vitality of the brain

through the partial or total cessation of the heart’s action, anddeath, from whatever cause produced, is only asphyxia. Inasphyxia, there is a want of arterial blood, and the mostobvious cure is, the supply of this by means well known tosurgeons of former times. Arterial blood was procured fromanimals, and a communication being established between theartery of the animal and that of the patient, a sufficientquantity was allowed to flow through an elastic tube, until theheart’s action was restored. It has been objected, that thereis a difference in the size of the blood globules of animals, ascompared with those of the human subject; but surely this canbe of no consequence, since the arteries and veins are largeenough to allow of the passage of globules twice the size ofthose contained in the blood of animals. I propose the use ofthis operation in all cases of approaching death; but we shouldnot hesitate to operate, even when the heart’s action hasceased. The brain dies before the heart, and there is no doubtthat life may be recalled, if there be but the minimum amountof pulsation in the heart. But we may even go beyond this,and assert, without fear of contradiction, that the heart’saction may be, and has often been, restored, after it had en-tirely ceased. Again, the heart’s action has sometimes onlyapparently ceased, only that the pulsations are not visiblethrough the thorax. If you poison a rat, and ’open thechest after all action of the vital functions has ceased, youmay witness the truth of what is here insisted on. Pureoxygen gas has been used with success, to restore the heart’saction after it has quite ceased; and so has galvanism,passed through the base of the brain and upper part of thespinal marrow; and so has brandy; and in the case of infantsborn asphyxiated, artificial respiration and the hot bathare often used to recal the play of the vital functions. In

asphyxia, the hot bath should be used at a high temperature,in order to produce the greatest effect in the least time, sincethe arterialization of the blood, by means of the skin, cannottake place to the full extent when the patient is in the bath.

On Suffocation by Drowning, and from Paralysis of the Musclesof the Larynx.

By S. GOWER, Esq., Surgeon, Hampstead.IN the instructions of the Humane Society, for the recovery

of persons apparently drowned, the popular remedy of hold-ing the drowned person up by the heels is justly condemned.It was no doubt popularly expected, that some pailfuls ofwater would run out at the mouth and nose in this posture.But it is desirable that, amongst other means used, the mouthshould be placed, not retained, in a depending position, toallow of any fluid escaping, by the force of gravitation, fromthe larynx. A case in point once occurred to me, which madean indelible impression on my mind. It was that of a child,not drowned, but with the muscles which assist in deglutitionpartially paralyzed. Some castor oil had been given, and, Ithink, a small dose of calomel, but it was doubtful whetherthey had passed the pharynx, and whether the epiglottis hadproved treacherous. There was difficult respiration, and aguggling sound in breathing. I had the child placed on itsside, or rather on its stomach, when some of the oil and aquantity of mucus flowed from the mouth and throat, and therespiration was immediately and entirely relieved. The childdied, but died less distressed and more easily than it wouldotherwise have done, presenting also a much less painful spec-tacle of apparent suffering. An attention to this circum-stance, in cases of apparent drowning, seems to be one of thosethings, the neglect of which would be an oversight.

Medical Societies.

ROYAL MEDICAL AND CHIRURGICAL SOCIETY.JUNE 27,3848.—J. M. ARNOTT, ESQ., F.R.S., PRESIDENT.

ON THE UTILITY OF TRISNITRATE OF BISMUTH IN THE DIARRHŒAACCOMPANYING PHTHISIS. By THEOPHILUS THOMPSON, M.D.,F.R.S., Physician to the Hospital for Consumption andDiseases of the Chest.

THE author considers the trisnitrate of bismuth to surpass inefficacy and safety our most approved remedies for this com-plaint. He has taken every opportunity, during the last

twelve months, of testing its powers, and has preserved notesof twenty-one of the cases in which it was administered. Ofthese, eighteen were phthisis in various stages of progress, andthree, bronchitis. In fifteen of the patients the diarrhaea wasentirely removed; in four, transient benefit was experienced,and the remedy proved useless only in two instances. Thedose administered was about five grains three or four timesdaily, usually combined with a little magnesia and gumarabic. Dr. Thompson has referred to various authors whohave written respecting the properties of bismuth, withoutbeing able to collect from them any evidence of its powers inthe phthisical variety of diarrhoea, but he entertains a strongconviction of its peculiar appropriateness to this affection, andhas obtained important confirmation of his experience in arecent communication from Dr. Lombard, of Geneva.

A PLAN OF TREATING OVARIAN DROPSY BY THE ULCERATIVEOPENING OF THE CYST AFTER ITS PERMANENT ADHESION TO THEWALLS OF THE ABDOMEN. By EDWARD JOHN TILT, M.D.The author was led to attempt this mode of cure by ob.

serving the process of Nature in some spontaneous and radicalcures of ovarian dropsy. His first object is, to establish solidadhesion between the peritonaeal covering of the cyst and theperitonseal lining of the abdominal parietes. His second ob-ject is, to make the smallest possible opening into the cyst, sothat it may not be suddenly emptied, but remain always full,and be only relieved per stilicidium of the overplus of liquiddistending its cavity, while it gradually contracts. To attainboth these objects he adopts the plan which has often beensuccessful in effecting the adhesion of hydatid cysts of theliver to the abdominal walls. It consists in the application ofVienna paste to the appropriate part of the abdomen. Herelates one case in which a radical cure of an ovarian cyst waseffected by this means.A lady, who had always enjoyed good health, ceased men-

struating at forty years of age. Soon afterwards, having beenexposed to cold, she was seized with violent pain in the left iliacfossa, followed by shivering and high fever. When these symp.toms were relieved, a tumour of the size of an orange was feltin the situation of the left ovary. This tumour graduallyincreased, and in a short space of time the patient had the ap.pearance of being advanced nine months in pregnancy. Viennapaste was applied to the pit of the stomach; an eschar wasproduced, and fell off, and afterwards a small opening wasformed by ulceration, through which an albuminous, ropyfluid escaped. The abdomen was supported by moderatepressure. In a few weeks the discharge became purulent andoffensive. Tepid water was then injected into the cyst dailyfor some months; the cyst gradually contracting, so that atlength it would receive only an ounce of water. In about a

year the patient was in effect well, although for several yearsa fistulous opening remained at the pit of the stomach. Inthe course of the case the cyst formed a communication withone of the intestines, and for several days the patient passedpurulent stools, while, during that time, no pus escaped fromthe external wound.

CASE OF HYDATID DISEASE OF THE LIVER CURED BY OPERATION.By GEORGE OWEN REES, M.D., F.R.S., Assistant-physician toGuy’s Hospital, and Principal Medical Officer to the Pen-tonville Prison.The case is detailed at some length. The patient was a man

aged thirty-one years; admitted into Guy’s Hospital on the13th of October, 1847. Examination of his abdomen detecteda distinct tumour occupying the right hypochondriac andepigastric regions. Fluctuation could be felt in it. On the4th of December the tumour was tapped by Mr. Hilton, witha trocar and canula not larger than an ordinary exploringneedle, straps of plaster having previously been passed roundthe body, so as to fix the tumour in position, and to exertpressure upwards. Thirty-eight ounces of clear fluid were re-moved. The wound quickly closed. On the 7th of January,the tapping was repeated with the same instrument, and withthe same precautions, as before. On this occasion pus of avery offensive odour escaped, and only ten ounces were ob-tained, owing to the canula becoming obstructed. On the 9thof January the tumour was tapped a third time with a full-sized trocar and canula, an elastic gum-tube being passedthrough the canula. Twenty-four ounces of foetid pus escaped,with membranous flakes, and partially-destroyed hydatids.The opening was maintained, and feetid pus, with, occasionallyhydatids, continued to be discharged (the capacity of the sacat the same time diminishing) till the commencement of April.On the llth of April the discharging orifice had closed, and