ROSTER OF ORGANIZING COMMITTEE. CHAIRMEN. SPEAKERS. AND PARTICIPANTS

Alexander. Nancy J •• NRRC/U.S. Department of Agriculture. Peoria. IL 61604 Andrews. Brenda J •• University of Toronto. Toronto. Ontario. Canada M5S 1A8

Bertrand. Helmut. University of Regina. Saskatchewan. Canada S4S OA2 Birky. C. William. Ohio State University. Columbus. OH 43210 Bozarth. Robert F •• Indiana State University. Terre Haute. IN 47809 Broach. James R •• Princeton University. Princeton. NJ 08544 Brown. Theodore. University of Illinois. Champaign. IL 61820 Burian. Richard M •• Virginia Polytechnic Institute. Blacksburg. VA 24601 Butow. Ronald A •• University of Texas Health Science Center. Dallas. TX

75235

Campbell. Judith L •• California Institute of Technology. Pasadena. CA 91125 Carbon. John A •• University of California. Santa Barbara. CA 93106 Chapman. Jerry L •• Eli Lilly and Company. Indianapolis. IN 46208 Chiu. Wan-Ling. Michigan State University. East Lansing. MI 48824 Collins, Richard A •• University of Toronto. Toronto. Ontario. Canada

M5S 1A1 Colson. Anne-Marie. Universit~ Catholique de Louvain. Louvain-A-Neuve.

Belgium B 1348 Cox, Michael M •• University of Wisconsin. Madison. WI 53706 Cummings. Donald J •• University of Colorado Health Sciences Center. Denver.

CO 80262

Dahlberg. Kurt R., Campbe'll Soup Company. Napoleon. OR 43545 Davis. Ronald W •• Stanford University School of Medicine. Stanford. CA

94305 Deters, Donald W •• Bowling Green State University. Bowling Green. OH 43403 De Vries. Gert E •• University of Leiden. Leiden. The Netherlands 2333 AL De Vries. Hans. University of Groningen. Groningen. The Netherlands

9712 KZ Dieckmann. Carol L •• University of Arizona. Tucson. AZ 85721 Dilts. Judith A •• William Jewell College. Liberty. MO 64068 Dujon. Bernard A •• Centre de G~n~tique MoI~culaire. Gif-sur-Yvette. France

91190 Dutcher. Susan K •• University of Colorado. Boulder. CO 80309-0347

Esposito. Rochelle. University of Chicago. Chicago. IL 60637 Esteban. Rosa. National Institutes of Health. Bethesda. MD 20892

Fearon. Kathleen. University of Massachusetts. Amherst. MA 01003 Fink. Gerald R •• Massachusetts Institute of Technology. Cambridge. MA

02139

557

558 ORGANIZING COMMITTEE, CHAIRMEN, SPEAKERS, AND PARTICIPANTS

Fujimura, Tsutomu, National Institutes of Health, Bethesda, MD Futcher, Bruce, McMaster University, Hamilton, Ontario, Canada

20892 L8N 3Z5

Gaillardin, Claude, Institut National Agronomique, Paris, France 75231-05 Garbutt, Jr., John T., Purdue University, West Lafayette, IN 47907 Gmunder, Hans, University of Bern, Bern, Switzerland 3012 Guarente, Leonard P., Massachusetts Institute of Technology, Cambridge, MA

02139 Gumport, Richard I., University of Illinois, Urbana, IL 61801 Gunge, Norio, Kumamoto Institute of Technology, Kumamoto, Japan 860 Gunsalus, I.C., University of Illinois, Urbana, IL 61801

Hager, Lowell P., University of Illinois, Urbana, IL 61801 Heckman, Joyce E., Indiana University, Bloomington, IN 47401 Heckmann, Klaus H., Universit~t MUnster, MUnster, Federal Republic of

Germany D-4400 Hefta, Laura J.F., Indiana University, Bloomington, IN 47405 Hightower, Robin C., University of California, San Francisco, CA 94143 Hinnebusch, Alan, National Institutes of Health, Bethesda, MD 20892 Ho, Nancy W.Y., Purdue University, West Lafayette, IN 47907 Howe, Gregg A., Sohio Research Center, Cleveland, OH 44128-2837 Huang, H.T., National Science Foundation, Washington, DC 20550 Hughes, Joanne E., Utah State University, Logan, UT 84322

Icho, Tateo, National Institutes of Health, Bethesda, MD 20892 Infanger, Ann, Seton Hall College, Greensburg, PA 15601

Jaehning, Judith A., Indiana University, Bloomington, IN 47401

Kaplan, Samuel, University of Illinois, Urbana, IL 61801 Kapler, Goeffrey, Harvard Medical School, Boston, MA 02135 Karl, Michael R., Indiana University, Bloomington, IN 47405 Kipp, Dawne V., Ohio State University, Columbus, OH 43210 Koduri, Kanaka Raju, Ingene, Inc., Santa Monica, CA ~0404

Koltin, Yigal, Tel Aviv University, Ramat Aviv, Israel 69978 Kuiper, Martin T.R., State University Groningen, Groningen, The Netherlands

9714 ET

Lamb, Mary Rose, University of Puget Sound, Tacoma, WA 98416 Lambowitz, Alan M., Ohio State University, Columbus, OH 43210 Laughnan, John, University of Illinois, Urbana, IL 61801 Lee, Pung-Choo, Michigan State University, East Lansing, MI 48824 Lee, Robert W., Dalhousie University, Halifax, Nova Scotia, Canada B3H 4J1 Leibowitz, M.J., Rutgers Medical School, Piscataway, NJ 08854 Lemieux, Bertrand, Universit~ Laval, Quebec, Quebec, Canada GIK 7P4 Lewin, Alfred S., Indiana University, Bloomington, IN 47405 Ligon, James M., U.S. Department of Agriculture, Peoria, IL 61604

Matsumoto, Yutaka, Purdue University, West Lafayette, IN 47907 Mayer, Stephen A., University of Arizona, Tucson, AZ 85721 Meacock, Peter A., University of Leicester, Leicester, England LEI 7RH Mets, Laurens, University of Chicago, Chicago, IL 60637 Miller, Dennis L., University of Texas at Dallas, Richardson, TX 75080 Morin, Gregg B., University of Colorado, Boulder, CO 80309-0215

Nargang, Frank E., University of Alberta, Edmonton, Alberta, Canada T6G 2E9

ORGANIZING COMMITTEE. CHAIRMEN. SPEAKERS. AND PARTICIPANTS

Neher, James B., Campbell Institute, Napoleon, OH 43515 Newman, Anita M., University of California, Irvine, CA 92717

Oeser, Birgitt, Ruhr-Universitat Bochum, Bochum, Federal Republic of Germany D-4630

Orozco, Buddy, University of Illinois, Urbana, IL 61801

559

Pande, Suchira, University of Alberta, Edmonton, Alberta, Canada T6G 2E9 Perlman, Philip S., Ohio State University, Columbus, OH 43210 Peterson, Celia, Indiana University, Bloomington, IN 47401 Phelps, Lisa G., University of Vermont, Burlington, VT 05405 Plewa, Michael, University of Illinois, Urbana, IL 61801 Podi1a, Gopi K., Indiana State University, Terre Haute, IN 47809 Preer, Jr., John R., Indiana University, Bloomington, IN 47405

Quackenbush, Robert, University of South Dakota Medical School, Vermillion, SD 57069

Queener, Stephen W., Eli Lilly and Company, Indianapolis, IN 46285

Rajbhandary, Uttam L., Massachusetts Institute of Technology, Cambridge, MA 02139

Ratzkin, Barry J., A}IGEN, Thousand Oaks, CA 91320 Richter, Rose1yne, Institut National Agronomique, Paris, France 75231-05 Rietveld, Krijn, Gist Brocades, Delft, The Netherlands Rochet, Michel, Institut National Agronomique, Paris, France 75231-05 Roeder, Shirleen G., Yale University, New Haven, CT 06511 Runge, Kurt W., Frederick Hutchinson-Cancer Research Center, Seattle, WA

98104

Sakaguchi, Kenji, Mitzubishi-Kasei Institute of Life Sciences, Tokyo, Japan 194

Samac, Deborah A., University of Wisconsin, Madison, WI 53706 Schmidt, Udo, T.U. Berlin, Berlin, Federal Republic of Germany 1000-65 Schuler, Mary A., University of Illinois, Urbana, IL 61801 Schulte, Erika, Ruhr-UniversitHt Bochum, Bochum, Federal Republic of

Germany D-4630 Schultz, Philip W., ~ndiana University, Bloomington, IN 47401 Schuster, Frederick L., Brooklyn Co11ege--CUNY, Brooklyn, NY 11210 Scott, John, University of Illinois, Urbana, IL 61801 Seale, Ron, Zymogenetics, Inc., Seattle, WA 98103 Sears, Barbara B., Michigan State University, East Lansing, MI 48824 Serizawa, Nobufusa, St. Louis University School of Medicine, St. Louis, MO

63104 Shepherd, Hurley S., U.S. Department of Agriculture, New Orleans, LA

70179 Sherman, Fred, University of Rochester Medical School, Rochester, NY 14642 Skinner, S.W., University of Chicago, Chicago, IL 60637 Skipper, Nigel, A11e1ix, Inc., Mississauga, Ontario, Canada L4V IPI Slonimski, Piotr P., Centre de G~n~tique Mo1ecu1aire, Gif-sur-Yvette,

France 91191 Soldo, Anthony T., Veterans Administration Medical Center, Miami, FL 33125 Stahl, U1f, T.U. Berlin, Berlin, Federal Republic of Germany 1000-65 Stark, Michael J .R., University of Leicester, Le'icester, England LEI 7RH Stevens, Lori, University of Illinois, Chicago, IL 60680

Thuriaux, Pierre, Centre d'Etudes Nuc1eaires de Sac1ay, Gif-sur-Yvette, France 91191

560 ORGANIZING COMMITTEE, CHAIRMEN, SPEAKERS, AND PARTICIPANTS

Ticho. Baruch S •• University of Chicago. Chicago. IL 60637 Tipper. Donald J •• University of Massachusetts Medical Center. Worchester.

MA 01605 Toh-e. Akio. Hiroshima University. Hiroshima. Japan 742 Tudzynski. Paul W •• Ruhr-UniversitHt Bo chum , Bochum, Federal Republic of

Germany D-4630 Turker. Mitchell S., University of Colorado Health Sciences Center, Denver,

CO 80262 Turmel, Monique. Universite Laval, Quebec, Quebec. Canada G1K 7P4 Tye. Bik-Kwoon, Cornell University. Ithaca, NY 14853

Van Alfen. Neal, Utah State University. Logan, UT 84322 Van Etten, James L •• University of Nebraska, Lincoln, NE 68583

Wade, Michael J., University of Chicago, Chicago. IL 60637 Wahls, Wayne P., University of Illinois Medical Center, Chicago, IL 60607 Weber. Eric R., University of Arizona, Tucson, AZ 85716 Wickner, Reed B., National Institutes of Health, Bethesda, MD 20892 Wilcoxen, Steve E., Indiana University, Bloomington, IN 47401 Williams, Keith L., Macquarie University, Sydney, Australia 2113 Wilson, Claire M., Council for Research Planning in Biological Sciences,

Inc., Washington, DC 20036-2077 Wise, Jo Ann, University of Illinois, Urbana, IL 61801 Wolfson, Ruth, Michigan State University, East Lansing, MI 48824-1312 Wu, Madeline C., University of Maryland, Baltimore County, Catonsville.

MD 21228

Yoder, D.C., Cornell University, Ithaca, NY 14853 Young, Paul G., Queen's University, Kingston, Ontario, Canada K7L 3N6

Zakian, Virginia A., Frederick Hutchinson Cancer Research Center. Seattle, WA 98104

Zallen, Doris T., Virginia Polytechnic Institute, Blacksburg, VA 24061

INDEX

88 357

538

AAG lysine codons, Acanthamoeba, 355, Acetyltransferases, Actinomycin D, 367 Adenosines, 339 Adenosylmethionine decarboxylase,

175 Adenylate cyclase, 450 ADH2, 546 AerObacter aerogenes, 349 Agaricus,

!. bisporus, !. bitorquis,

Agrobacterium,

149 105

446 Alanine, 338 Ala-Pro-Phe-His-Phe-Trp. 62 Algae, 39, 67

Chlorella-like green, 337 PBCV-1, 338 viruses, 337

a Amanitin-resistant mutants, 522 Ameba, 441

Amoeba proteus, 363 cytosol, D and xD, 364 dysentery, 349 eukaryotes, 439

Amebaflagellate, Naegleria, 261 e-Amino-n-caproic acid, 76 Aminopeptidases, 538 Ammonium sulfate precipitation,

249 Anabaena, 133 Aphidicolin. 464 Apocytochrome c, 533, 542 Apoprotein, 39 ARC1. 78 Archaebacteria, 439, 519 Arginine, 538

prototrophy, 68 Argininosuccinate lyase, 68 Arg77 protein, 540 ARS08, 78 ARS plasmids, 378 ASCobolus, 122

A. immersus, 83, 449

Ascomycetes, 63 Asparagine, 538

residues, 216 Aspergillus, 83, lOS, 131, 149

A. amstelodami, 102 A. foetidus, 180 A. giganteus, 254 A. nidulans. 112

Assembly mutants (fla), 303 ATPase, 39 ---AT-rich stretches, 29, 67 AUG codon, 534 AU-rich bubble, 247 Autonomously repeating sequences,

499 ARS elements, 463 specificity of DNA binding

protein, 470 Axenic strains, 443 Axonemal phenotypes, 311

Bacterial transposons, 407 Bacteriophages,

Bacillus, 450 chromosomes, 407 lambda DNA, 450 Md, 407 P1, 407

BamHI, 168 site, 73, 291

561

BamHI/SspI CEN3 fragment, 482 Barley, 249 Basal body, 303

preparations, 311 Base-pairing interactions, 41 Basidiomycetes, 249 Benzamidine, 76 . Brassica, 122, 449, 451 5-Bromo-2'-deoxyuridine (BrdUrd),

354

Caedibacter, 265, 279 C. paraconjugatus, 267, 272 c. pseudomutans, 267, 272 c. taeniospiralis, 267, 268, 279

562

Caedibacter, continued, C. varicaedens, 267, 272, 279

Canavanine-resistant clones, 528 Candida pseudotropicalis, 450 Carboxymethylcellulase

(CM-cellulase), 221 CARGA, 546 CAiGB, 546 castanea dentata Borkh., 227 Cauliflower mosaic virus, 87 CDC genes, -cnC16, 166

iiiU'tations, cdc8, 463 cdc9, 463 CdcI6-1, 167

Cellulase gene, in bacteria, 220 Cellulomonas fimi, 221 Centromeres, 479

binding proteins (CBPs), 481 CBP-CEN DNA interaction sites,

486 CEN, --CEN3, 481, 482, 485

CEN14, 485 Wi'Id=type, 479

of sister chromatids, 321 CGN arginine codons, 88 Chaos carolinensis, 363 Chemoattractant 3'5' cyclic AMP,

444 Chestnut blight, 227

control by hypoviru1ence, 235 Chick embryo fibroblasts, 356 Ch1amydias, 329 Chlamydomonas, 237

C. reinhardtii, 67, 303, 304, - 341 C. sp. strain WXM, 71

Chloramphenicol, 331 Chlorella, algal viruses, 337 Chloroplasts, 67

DNA replication, 67 genes, 40

of algae, 39 Chromosomal genes, 151

affecting double-stranded RNA replication, 165

Chromosomes, 479 VIII, 165

Chromosome-sized DNA, 494 Cis-acting mutations, 533 Claviceps, 119, 122, 451

£. purpurea, 84, 105, 119, 449 Clonal deterioration, 93 Cobalt resistance mutation,

cob-354, 440

INDEX

cob Intron 4, 41 COChliobo1us heterostrophus, 83,

105 Concatemers, 286 Conconava1ine A, 251 Corn, 67

smut, 239 Corynebacterium diphtheriae, 359 Creatine kinase, 76 Creuzfe1dt-Jakob disease, 357 Crossover points, 399 Cryphonectria parasitica, 227 Cryptop1eurine, 176 Cyanobacterium, 133 CYC genes, --CYCl, 513, 542

mRNA initiation region, 514 CYC3, 541, 542 CYc7, 542 iiiUt'ations,

CYC1j239-0, 536 CYC1 + cyc1-x + CYC1-x-y, 537

Cycloheximide, 367 cyt18-1, 61, 64 Cytidines, 339 Cytochrome-deficient "stopper"

variants, 94 Cytochromes,

!!3' 57, 93 b, 57, 93

apoprotein of, 39 gene, 5

c, 533 - heme lyase, 540

iso-I-cytochrome c, iso-2-cytochrome C, oxidase, 39 -

synthesis, in yeast, Cytoduction, 239 Cytoplasms,

[+], 93 [ka1], 93 element, [KIL-b] , 158

Cytosol, 84 ribosomes, 533

dATP, 76 dCTP, 76 Delta sequences, 545 Deoxynuc1eotide, 76 dGTP, 76 Dicistronic mRNA, 61 Dictyoste1ium, 357

513, 533 533

515

D. discoideum, 439, 441 - amebas, 441

axenic strains, 443

INDEX

Dictyostelium. continued. D. discoideum. continued. - transformation. 444

Dikaryon rescue analysis. 306 D-Loops, 67, 71 DNA,

-binding protein, 470 double-stranded circular molecule,

407 ligase, mutants, 463 methyltransferase, 339 polymerase I, 464 topoisomerase I, 166

Double-stranded RNA, 161, 173, 203, 215

dependence of M on L, 174 families of,

L-A, 149, 151 L-BC, 149, 151 M, 149 T, 149 W, 149

genomic segments, 174 replication, 149, 165, 179

Drosophila, 315, 377 ~.melanogaster, 522

Drug inhibition, 464 dTTP, 76

EcoRI-E DNA, 95 Emetin, 367 Endo-1,4-S-D-glucanase, 221 Endosymbionts, 265, 363, 368 Endothia parasitica, 149, 227, 236 Entamoeba histolytica, 349 Enzymes, 408 Epsilon region, in Saccharomyces

cerevisiae, 545, 552 Ergot,

alkaloids, 119 fungus, 449

Escherichia coli, lacZ, 379-­single-stranded

protein, Euglena gracillis, Euplotes,

E. aediculatus, - 332

408

DNA binding 467

67

327, 328, 331,

E. daidaleos, 332 E. eurystomus, 332 E. octocarinatus, 332 E. patella, 332 E. plumipes, 332 E. woodruffi, 332

Excision-amplification, 129, 141 Extrachromosomal DNA, 439

Extrachromosomal elements, 239, 265

563

Extramitochondrial plasmid, 93 Extramitochondrial precursor, 533

Fiji mitochondrial plasmids, 85 Filamentous fungi, 83 Fish lymphocystis disease virus,

345 fla Mutations, fla9, fla10, and - fla19, 307 --FLP recombination system, 377 --riP-DNA complexes, 409

flp mutant 2-micron circle, 383 function of FLP, 430 protein, 383, 403

binding domain, 411 binding sites, 401

Fluorochrome N,N'-diethylpseudo-isocyanin chloride, 328

Frog virus 3, 345 Fungal viruses, 239 Fusarium oxysporum, 123

f. sp. conglutinans, 105

S-Galactosidase, activity, 550 expression, 482, 486, 516

GAL genes, GALl,

--expression, in yeast, 481 -lacZ, 481, 486

GAL~513 GALlO,

-FLP, 383 promoter, 379

Glumannomyces graminis var. tritici, 123, 231

galK Expression plasmid, 75 GC-rich regions, 29 Genes,

cloning, 519 derivatives, 547 expression, 545

Genetic activities, [HOK], [EXL], [NEX], 150

Genomes, organization, 60 segments, 174

(l,6)-S-D-Glucan, 254 Glutamic acid, 538 Glycine, 538 Grasses, 249 G-Rich sequence, 536 Guanine, 40 Guttulinopsis vulgaris, 443

564

HAPl, 515 HAP2, 515 HAP2-beta-galactosidase fusion

protein, 516 HAP3, 515 Heat inactivation, 249 HeLa cells, 46 Helicases, 467 Helminthsporium,

H. car bonum, 248 :E. maydis, 248 H. turcicum, 248 :E. vagans, 248

Heme-activating proteins, 515 hem Mutants, 533 Hepes, 76 Herpes viruses, HSV-l and HSV-2,

393 Heterothallic species, 239 HindIII-HincII fragment, 116 hii4-917 Mutation, 547 Homopyrimidine sequences, 58 Host factors, in nuclear plasmid

maintenance, 499 Human adenovirus genome, 450 Human embryonic brain cells, 356 Human papilloma virus, 345 Hump killing, 266 Hypovirulence, 227, 235

Immunological screening, 522 Incompatibility, 239 Intact target sequence, 409 Intermediate filament protein, 388 Interstrain inhibition, 239 Intracistronic complementation,

249 Introns, 30, 32, 133

Class II, 17 cob, 41 mitochondrial, 5

proteins encoded by, 5 splicing apparatus, 142

Iridoviruses, 345 fish lymphocystis disease virus,

345 frog virus 3, 345

Isogenic, plasmid-free strains, 122

Isoleucine, 538

kalilo, DNA, 84, 105 junctions with mtDNA, 96 senescence factor, 93 strains, 93

Kappa, 262, 265

Kappaphages, 271 [KIL-b], 158

INDEX

Killer paramecia, 265 Killer-phenotype, 327 Killer strains, 239, 241 Killer system, ~39 Killer yeasts (K phenotype), 189 K~netochore, 479 K ,

ionophore, 450 protonophore, 450

Klebsiella, 353 K. pneumoniae, 349

Kluyveromyces, 122 !. fragilis, 5, 15, 450 K. lactis, 452 - IFO 1267, 449

CBS 2359, 449 !. thermotolerans, 17

LaBelle mitochondrial plasmid, 85 lacZ, 379 Large, polyhedral, dsDNA-containing,

chloroform-sensitive viruses, 341

Lariat, 44 LEU2, 201 Leucine, 538 Linkage group XIX, 316

interference on, 319 segregation of, 316

Long-range dyad sequence, 138 Lysine, 538

Magnesium acetate, 76 Magnesium ion, 43 Maize, 108, 315

mitochondrial plasmids, 84 MAK,

genes, MAKI0, 149 MAKll, 165, MAK16, 167 MAK18, 168 MAK31, 149 MAK32, 149

mutations, mak3, 151 maklO, 151

MAL 62,""""20 1

166

Mate killing, 267 Mauriceville mitochondrial plasmids,

84, 85 Meiotic divisions, first and second,

479 Methionine, 538

aminopeptidases, 538

INDEX

6 . 6 N6-Methyldeoxyadenosine ~m dA). 339 5-Methyldeoxycytidine (m dC). 339 N-Methyl-N'-nitro-N-nitroso-

guanidine. 457 Microtubule-like elements. 351 Minichromosomes. 499

maintenance. 500 Miso. 425 Mitochondria.

chromosomes. 93 DNA.

defective. 83 of Neurospora~. 57 petite. 59 sMt. 137 unstability of. 94

gene. 59. 60 complement, 93 expression, 39

translocation, 533 MKT1, 165, 168 Mobile genetic elements. 5, 29, 89 Molecular phenotypes. 313 Morchella, 122

~. conica. 449 Mosaic genes, 39 Multiple sclerosis. 352 Mutagenic treatments, 242 Mycoplasmas. 329 Mycoviruses. 149

NADH-dehydrogenase. 62. 63 Naegleria. 261, 263

N. fowleri. 349. 356 !. gruberi. 349. 356 life cycle, 352

Nectria haematococca, 105 Neurospora, 83. 539

N. crassa. 105 - mitochondrial DNA of. 57

mutants of, ~[E35], 57. 83 strains of. Mauriceville-Ie,

85 N. intermedia, 84. 93. 105. 131

strains of, P405 LaBelle and Fiji N6-b, 85

~. tetrasperma. 85, 105 Nick-translation products,

radioactive, 95 Nitrogen starvation, 176 Nontandem inverted repeats. 376 Nucleus.

chromosomes. 304 lamina and pore complexes. 379,

388 matrix. 388

Nucleases, 249

Nucleotide sequences. 192 Null alleles. 522

Oats, 249 Omega~. 5 Omega. 5 Omikron-like endosymbionts, 327 Open reading frame. 30

of intron. 30 Ovaries, 119

Palindromes, Alu-. 61 dimers, 439 PstI-. 58

Paralysis. 267 Paralyzed mutants (Ef), 303 Paramecia.

endosymbionts of. 265 killer. 265 Paramecium. 279. 358

P. aurelia complex. 329 P. biaurelia. 266, 279 P. bursaria. 337 P. tetraurelia. 266. 279

Paraiiiecin, 281

565

Parauronema acutum, 291, 292. 334 PBCV-1. 338---Pelomyxa palustris. 363 Penicillium. 149

f. chrysogenum. 247 P. stoloniferum. 177, 180

Perivascular macrophages, 352 PET.

genes. PET3. 165, 168 PET18, 149. 189

mutations. pet18. 151, 189

Phagocytosis. 352 Phenyl methylsulfonyl fluoride, 76 Pheromone B factor. 179 Physarum. 439

f. polycephalum. 439 Pichia membranaefaciens. 341 Piericidin A, 62 Plasmids,

ARS. 378 pJDJH, 48 pJDL\2, 48 pKO. 75 pYe arg4. 68 T40. 109 amplification. 375 in eukaryotes. 439 extramitochondrial. 93 galK expression. 75

566

Plasmids, continued, linear DNA, 449 maintenance, effects of nuclear

mutations, 175 2-micron circle, 375, 392, 397,

407 2-micron DNA-like plasmids, 425 mitochondrial, 83

in Cochliobolus heterostrophus, 105

excision-amplification, 129, 141

Fiji, 85 LaBelle, 85 in maize, 84 Mauriceville, 84, 85 Varkud, 84, 85

nuclear, 440 maintenance, 499

Podospora, 83, 102, 105 P. anserina, 102, 109, 124, 129

poll Mutants, 465 Poly(A)-containing RNA, 435 Polyamines, 155 Polygenic primary transcript, 39 Polymorphic region, 67 Polypeptides, 249 Polysaccharides, 254 Porphyrin, 533 Post-translational processing, 533 Preaggregation phase, 444 Prepropolya-factor, in yeast, 221 Preprotoxin, 215, 221

coding region, 216 gene, in M1 double-stranded RNA

of yeast, 215 Primary amebic meningoencephalitis

(PAM), 349, 356 Proteases, 249 Protein toxin, 189 Proteins,

genes, 60 URF2 (ND2), URF3 (ND3),

intron-encoded, ribosomal, 39 toxin, 189

60, 63 60

5

Protozoans, marine, 291 pSB3, 436 Pseudomonas phaseolicola, 176, 179 Pseudorabies virus, 393 PuPuPyPuPu, 514 Putrecine, 175 PYK1, 541

Rat glioma cells, 356 Recombination, 409

Recombination, continued, site, 398

specificity to, 407 Reovirus, 174 Replication, 463

bidirectional, 422 of double-stranded RNA, 179 intramolecular, 430 modes,

rolling circle, 375 theta, 375

sequential nature, 176 Repressor, 481 REP stabilization system, 377 Restriction endonucleases,

BglII, 482 Hpal, 482 map, Rochaix, 69

INDEX

Reverse transcriptase mechanism, 132

Rhizobium, 446 Rhizoctonia solani, 123, 449 Ribosomal RN-A-,----

genes, 439 21S, alleles of, 29

Rickettsias, 329 Rifampicin, 331 RNA,

mRNA initiation region, in CYC1, 514

polymerases, 230, 519 II, 513 subunits A, B, and C, 519 virus-associated, 245

Saccharomyces, S. bisporus, 426 S. carlsbergensis, 375 S. cerevisiae, 5, 59, 149, 173,

189, 215, 245, 341, 375, 4~7, 439, 449, 479

omega, 5 ~. kluyveri, 451

Sall, 168 SChizosaccharomyces,

Sch. pombe, 5, 17 class II intron of, 17

Sclerotia, 119 SDS Tetrads, 318 Secale, 123 senDNAs, 131

Band €, 131, 133 Senescence, 93

cultures, 129 Single-stranded DNA-binding protein,

in Escherichia coli, 467 SSB1, SSB2, and SSBm, 468

INDEX

Sister chromatids. centromeres of. 321

ski Mutations. ski1. 151

ski2. 151 ski3. 151 ski4. 151 ski6. 151 ski7. 151 ski8. 152

Slime mold. Dictyostelium discoideum. 439. 441

Soil amebas. 363 Soil ameboflagellate. 349 Sorghum bicolor. 122 Soy sauce. 425

fermentation. 377 Spermidine. 43. 155. 175 Spermine. 155. 175 Sphacelial mycelium. 119 Spheroplasts. 254 Spin killing. 267 SP012. 168 SstI. 168 STE7. STEll. and STE12. 546 Stem-loop structures:- 75 Stopper (!!2) mutants.

of Neurospora. 57. 83 Streptomyces. 451

S. rochei. 449 Structural genes. 522 SUF8. 168 sun Mutations. 304 Suppressive accumulation. 102 Symbiosis. 261

symbionts. 261 intracellular. 291

TATA box factor. 513 TC PuA. 514 Telomeres. 500

associated sequences. 493 Temperature-sansitive mutants.

465. 528 Terminal inverted repeats. 120.

121 Tetrahymena. 60. 134. 355. 439.

450 !. thermophila~5 42. 439 labeled with [ S]methionine.

366 Tetramitus. 357 Threonine. 538

termini. 538 Thylakoid membrane. 76 Thymidine. 354 Thymidylate kinase. 463

Topoisomerases. topoisomerase I. temperature­

sensitive defect. 175 topoisomerase II.

clone. 165 gene. 168

Toxins. 249

567

specificities. KP1. KP4. and KP6. 247

Trans-acting factors. 515 Translation. 533 Transnuclear structure. 375 Transposable elements. 545 Transposase. 5. 32

intron-encoded. 8 omega. 5. 7

activity. 7 Transposons. 271 Trimethyllysine 77. 539 Tri~let ~icrotubules. 303 TRP URA transformants. 465 Two-micron circle. 375. 392. 397.

407 flp mutant. 383 2-micron DNA-like plasmids.

Ty (!ransposon zeast) elements.

UGG tryptophan codons. 88 uni1. uni2. and uni5. 304 Uracil:--40 ----Uronema. 291 Ustilago. 149

!!. maydis. 239

Valine. 538 var1. 32

425 545

Varkud mitochondrial plasmids. 84 Vimentin. 388 Virions. 245 Viruses.

capsid. 240 disease. suppressors of. 169 functions. mapping of. 246 induction. 353 nucleic acids. 241 particles. 240 subtypes. 243 toxins encoded by. 248

Virus-like particles. 349 cycles of. 155 intracellular. 149 intranuclear development of. 350

Wheat. 249 germ. 539

Yeast. 215. 221. 375

568

Yeast, continued, chromosomes, 479, 500 CYC1, 513 cytochromes,

isocytochromes, 533 synthesis of, 515

epsilon region, 545, 552 GALl expression, 481 gene,

expression, 545 library, 167

karyoskeletal component, 378 kinetochore, 479 non-Saccharomyces, 425 osmophilic, 392 petite mutants, 83 plasmid 2-micron circle, 375,

397, 407 strains, AB972, A364a, YNN281,

DC04, and RDa5, 494

Xenosome, 291, 329 killer, 291 nonkiller, 291

Zea mays, 449, 451 Zygosaccharomyces, 377, 425

Z. bailii, 425, 426 ~. bisporus, 377 ~. fermentati, 425 Z. japonicum Saito, 426 Z. naniwaensis HUT 7185, 426 Z. rouxii, 377, 425, 426

INDEX