Research Advances in Cystic Fibrosis

Expert Interpretations and Clinical Insights

Data on Nebulized Levofloxacin and Guidance on Psychosocial

Support

Nebulized Levofloxacin For Chronic P aeruginosa infection

Results

Results (cont)

Depression and Anxiety in Patients With CF

Best Practice Guidelines: Psychosocial Support

Best Practice Guidelines: Psychosocial Support (cont)

Key Transition Points

An Update on Ivacaftor and the Evolving Role of MRI

Background

KONDUCT Study

KONDUCT Study (cont)

Additional Findings

Additional Findings (cont)

Investigators’ Conclusion

MRI Detection of Lung Ventilation Defects in CF

Additional Results

MRI Assessment of Response to Therapy

Additional Findings

Take-home Points

MRI Evaluation of Pulmonary Blood Flow

Take-home Point

Recommendations For Exercise and For CFTR Modulator Therapy

The Importance of Exercise in CF

Results

Best Practices: CFTR Modulator Therapy

Best Practices: CFTR Modulator Therapy (cont)

Best Practices: CFTR Modulator Therapy (cont)

The Ronan et al Study

Does Ivacaftor Improve Lung Function By Altering Airway

Microbiology?

Effect of Ivacaftor on Mucociliary Clearance

KONNECTION Study

Results

Take-home Points

New Findings on Inhaled Antibiotic Therapies

Once-daily Inhaled Liposomal Amikacin

Study Design

Highlights of Efficacy Results

Highlights of Efficacy Results (cont)

Highlights of Safety Results

Take-home Point

Incorporating a Third Inhaled Antipseudomonal Antibiotic Class

Highlights of Results

Highlights of Results (cont)

Abbreviations

References

References (cont)

References (cont)