reeves lab – level 5 peter reeves gordon stevenson yaoqin hong vincent morales

3
Reeves Lab – Level 5 Peter Reeves Gordon Stevenson Yaoqin Hong Vincent Morales

Upload: clemence-montgomery

Post on 17-Jan-2016

224 views

Category:

Documents


1 download

TRANSCRIPT

Page 1: Reeves Lab – Level 5 Peter Reeves Gordon Stevenson Yaoqin Hong Vincent Morales

Reeves Lab – Level 5 Peter Reeves

Gordon Stevenson

Yaoqin Hong

Vincent Morales

Page 2: Reeves Lab – Level 5 Peter Reeves Gordon Stevenson Yaoqin Hong Vincent Morales

Research interests of Reeves Lab

Bacterial pathogenesis and evolution - Examining evolutionary relationships of pathogens eg. Shigella are clones of E. coli that have multiple unrelated origins Relationships between Vibrio cholerae pandemic and endemic strains

- Genetic and functional basis for bacterial cell surface polysaccharide eg. Genetics and structures of bacterial capsules, O antigens… Roles of O-antigen synthetic proteins, eg. Wzx, Wzy… Protein specificity associated with surface polysaccharide assebmly

Page 3: Reeves Lab – Level 5 Peter Reeves Gordon Stevenson Yaoqin Hong Vincent Morales

Techniques/Tools that we use

Traditional molecular biology tools - cloning - site directed knockout/knock in - 1 D PAGE - Immunoblot Also - Sequencing (sanger, ilumina, 454…) - Radioisotope labeling - bioinformatics - possibly protein related work