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  • Recent Advances in Synthesis& Chemical Biology IX___________________________

    Symposium10th December 2010

    Davenport Hotelat Merrion Square,Dublin 2

  • Recent Advances in Synthesis and Chemical Biology IX10th December 2010

    The Centre for Synthesis and Chemical Biology wishes to thankthe following sponsors for their support for this symposium:

  • Centre for Synthesis & Chemical

    Recent Advances in Synthesis and Chemical Biology IX

    Davenport Hotel, at Merrion Square, Dublin 2, Ireland

    08.50am-9.00am Opening sessionDr. David Lloyd, Dean of Research, Trinity College DublinProfessor Mathias Senge, Trinity College Dublin

    9.00am-09.45am Chairperson: Professor Marek Radomski, Trinity College DublinDRHEA LectureProfessor Itamar Willner,IsraelSensing with Nanoparticles, Quantum Dots and Biomolecular Nanostructures

    09.45am-10.30am Chairperson: Professor Kevin Nolan, Royal College of Surgeons IrelandDRHEA LectureDr. AnneBiochemical Approaches to Biomolecular Networks

    10.30am-11.00am Coffee/Tea Break

    11.00am-11.45am Chairperson: Dr. Wolfgang Schmitt, Trinity College DublinDRHEA LectureProf. Pierre Braunstein, Universit Louis Pasteur, Strasbourg, FranceThe Chemistry of Heterofunctional Ligands: from Homogeneous Catalysts to 1Bimetallic Wires and Clusters

    11.45am-12.30pm Chairperson: Dr. Cormac Murphy, University College DublinInstitut de Recherches ServierProfessor David O'Hagan,The stereoelectronic influence of the C

    12.30pm-1.45pm Lunch Break

    1.45pm-2.30pm Chairperson: Professor Pat Guiry, University College DublinGlaxoSmithKline LectureProfessor Reinhard Brckner, Universitt Freiburg, Freiburg, GermanyEvolution of a Synthetic Strategy Towards the Unnatural Enantiomer of thePolyol/Polyene Antibiotic Nystatin AChemoselective

    2.30pm-4.00pm Poster Session. Coffee/Tea Break

    4.00pm-4.45pm Chairperson:Eli Lilly LectureProfessor Bernhard Krutler, Universitt'News on an Old Puzzle

    4.45pm-5.00pm Closing RemarksProfessor Pat Guiry, Director, Centre for Synthesis and Chemical Biology

    5.00pm-6.00pm Wine Reception in the Restaurant, 1

    Centre for Synthesis & ChemicalBiology

    Recent Advances in Synthesis and Chemical Biology IXFriday, 10th December, 2010

    Davenport Hotel, at Merrion Square, Dublin 2, Ireland

    PRELIMINARY PROGRAMME

    Opening sessionDr. David Lloyd, Dean of Research, Trinity College DublinProfessor Mathias Senge, Trinity College Dublin

    Chairperson: Professor Marek Radomski, Trinity College DublinDRHEA LectureProfessor Itamar Willner, The Hebrew University of JIsraelSensing with Nanoparticles, Quantum Dots and Biomolecular Nanostructures

    Chairperson: Professor Kevin Nolan, Royal College of Surgeons IrelandDRHEA LectureDr. Anne-Claude Gavin, EMBL, Heidelberg, GermanyBiochemical Approaches to Biomolecular Networks

    Coffee/Tea Break

    Chairperson: Dr. Wolfgang Schmitt, Trinity College DublinDRHEA LectureProf. Pierre Braunstein, Universit Louis Pasteur, Strasbourg, FranceThe Chemistry of Heterofunctional Ligands: from Homogeneous Catalysts to 1Bimetallic Wires and Clusters

    Chairperson: Dr. Cormac Murphy, University College DublinInstitut de Recherches Servier LectureProfessor David O'Hagan, University of St. Andrews, St. Andrews, UKThe stereoelectronic influence of the C-F bond for design in organic chemistry

    Lunch Break

    Chairperson: Professor Pat Guiry, University College DublinGlaxoSmithKline LectureProfessor Reinhard Brckner, Universitt Freiburg, Freiburg, GermanyEvolution of a Synthetic Strategy Towards the Unnatural Enantiomer of thePolyol/Polyene Antibiotic Nystatin A1 - The -Lactone Approach to 1,3Chemoselective Hydrogenations of -Ketocarboxylic Acid Derivatives

    Poster Session. Coffee/Tea Break

    Chairperson: Professor Thorfinnur Gunnlaugsson, Trinity College DublinEli Lilly LectureProfessor Bernhard Krutler, Universitt Innsbruck, Innsbruck, Austria'News on an Old Puzzle - Chlorophyll Breakdown in Leaves and Fruit'

    Closing RemarksProfessor Pat Guiry, Director, Centre for Synthesis and Chemical Biology

    Wine Reception in the Restaurant, 1st Floor, Davenport

    Investing in your future

    Recent Advances in Synthesis and Chemical Biology IX

    Davenport Hotel, at Merrion Square, Dublin 2, Ireland

    Chairperson: Professor Marek Radomski, Trinity College Dublin

    The Hebrew University of Jerusalem, Jerusalem,

    Sensing with Nanoparticles, Quantum Dots and Biomolecular Nanostructures

    Chairperson: Professor Kevin Nolan, Royal College of Surgeons Ireland

    Prof. Pierre Braunstein, Universit Louis Pasteur, Strasbourg, FranceThe Chemistry of Heterofunctional Ligands: from Homogeneous Catalysts to 1-D

    Chairperson: Dr. Cormac Murphy, University College Dublin

    University of St. Andrews, St. Andrews, UKF bond for design in organic chemistry

    Chairperson: Professor Pat Guiry, University College Dublin

    Professor Reinhard Brckner, Universitt Freiburg, Freiburg, GermanyEvolution of a Synthetic Strategy Towards the Unnatural Enantiomer of the

    Lactone Approach to 1,3-Diols andKetocarboxylic Acid Derivatives

    Professor Thorfinnur Gunnlaugsson, Trinity College Dublin

    Innsbruck, Innsbruck, AustriaChlorophyll Breakdown in Leaves and Fruit'

    Professor Pat Guiry, Director, Centre for Synthesis and Chemical Biology

    Investing in your future

  • Invited Speakers:

    Profiles

  • Professor Itamar Willner, The Hebrew University of Jerusalem, Jerusalem,Israel

    Itamar Willner obtained his PhD in 1978 in Physical Organic Chemistry. Hemoved on the U.C. Berkeley where he studied as a post1980) and served as Staff Scientist and Adjunct Association Professor (19801981). He was appointed as a Lecturer in the(1981) and later became a Professor in the same University (1986).

    He has co-authored over 580 publications and over 30 patents. His researchactivities include Supramolecular chemistry, Nanotechnology,Nanobiotechnology and Molecular selfawards and honours including the Bergmann award (1986), the Kolthoff Award(1993), the Kaye Innovations Award (1998 and 2004), the Israeli prize inChemistry (2002) and the EMET prize in chemistry (underPrime Minister of Israel) - 2008.

    He served as an Honorary Professor in Osaka University (1991) in TsinghunaUniversity Beijing, China (2005), in the East China University of Science andTechnology, Shanghai, China (2007). He was electAcademy of Science (2002), a member of the European Academy of Scienceand Arts (2004), a fellow of the Royal Society of Chemistry (FRSC) (U.K.)(2009) and a member of the German National Academy of Sciences Leopoldina(2009)

    Dr Anne-Claude Gavin, EMBL, Heidelberg, Germany

    Anne-Claude Gavin obtained her PhD in the University of Geneva, Switzerlandin 1992. She conducted her postBiology Laboratory (EMBL) in Heidelberg and became a director of Molecularand Cell Biology, Cellzome AGat EMBL since 2005.

    She has co-authored over 35 publications, with the most recent beingVisualizing biological data -data for systems biology. She received the Genome Technology AllMost Prolific in Proteomics in 2002 for her work on the "Functional organizationof the yeast proteome by systematic analysis of protein complexes".

    EMBL, one of the world's top research institutions, ismonies from 20 member statesFrance, Germany, Greece, Iceland, Ireland, Israel, Italy, Luxembourg, theNetherlands, Norway, Portugal, Spain, Sweden, Switzerland, The UnitedKingdom and an associate member state, Australia.

    The cornerstones of EMBL's mission are: to perform basic research in molecularbiology, to train scientists, students and visitors at all levels, to offer vitalservices to scientists in the member states, and to devmethods in the life sciences, and technology transfer.

    Professor Itamar Willner, The Hebrew University of Jerusalem, Jerusalem,

    obtained his PhD in 1978 in Physical Organic Chemistry. Hemoved on the U.C. Berkeley where he studied as a post-doctoral fellow (19781980) and served as Staff Scientist and Adjunct Association Professor (19801981). He was appointed as a Lecturer in the Hebrew University in Jerusalem(1981) and later became a Professor in the same University (1986).

    authored over 580 publications and over 30 patents. His researchactivities include Supramolecular chemistry, Nanotechnology,

    d Molecular self-assembly. He has received numerousawards and honours including the Bergmann award (1986), the Kolthoff Award(1993), the Kaye Innovations Award (1998 and 2004), the Israeli prize inChemistry (2002) and the EMET prize in chemistry (under the auspices of the

    2008.

    Professor in Osaka University (1991) in TsinghunaUniversity Beijing, China (2005), in the East China University of Science andTechnology, Shanghai, China (2007). He was elected a member of the IsraeliAcademy of Science (2002), a member of the European Academy of Scienceand Arts (2004), a fellow of the Royal Society of Chemistry (FRSC) (U.K.)(2009) and a member of the German National Academy of Sciences Leopoldina

    Claude Gavin, EMBL, Heidelberg, Germany

    Claude Gavin obtained her PhD in the University of Geneva, Switzerlandin 1992. She conducted her post-doctoral research in the European Molecular

    (EMBL) in Heidelberg and became a director of Molecularand Cell Biology, Cellzome AG in Heidelberg. She has served as a group leader

    authored over 35 publications, with the most recent beingnow and in the future and Visualization of omics

    She received the Genome Technology All-Stars AwardMost Prolific in Proteomics in 2002 for her work on the "Functional organizationof the yeast proteome by systematic analysis of protein complexes".

    EMBL, one of the world's top research institutions, is funded by public researchmonies fro

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