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Research review of the past year (2004-05) [email protected]

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Page 1: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

Research review of the past year (2004-05)

[email protected]

Page 2: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

Scope

• All frequency ranges• Laboratory investigations on cellular,

animal and human models• No epidemiology• No hypersensitivity

Page 3: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

Static: animals

• Hypertensive rats

Page 4: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

Static: animals

• Bird navigation: RPM

Page 5: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

ELF: humans

• PEMF

Page 6: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

ELF: humans

• Cognitive functions

Page 7: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

ELF: cells

• PEMF: neurite outgrowth

Page 8: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

ELF:cells

• DNA damage

Page 9: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

ELF: cells

• Review on genotox

Page 10: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: humans

• Dosimetry

Page 11: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: humans

• Thermophysiology

Page 12: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: humans

• Cognitive functions

Page 13: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: humans

• Cognitivefunctions inChildren

Page 14: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: humans

• Cognitive functions

Page 15: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: humans

• EEG, rCBF,sleep

Page 16: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: animals

Rat bioassay

Page 17: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: animals

• Memory

Page 18: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: animals

• BBB: ongoing replications of the Salford et al. data on BBB leakage and “dark neurons”

• Pim1 transgenic mice lymphoma: Perform-A study negative

• DMBA-induced tumours: ?• Rat and mice bioassays: ?

Page 19: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: animals

• Melatonin

Page 20: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: cells

• Immune system

Page 21: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: cells

• DNA damage

Page 22: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: cells

• ODC activity (replication of the Litovoitz data): negative

• All data from the Perform B programme on genotoxicity negative

Page 23: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

RF: cells

• Endocytosis

Page 24: Research review of the past year fileControversial Cytogenetic Observations in Mammalian Somatic Cells Exposed to Extremely Low Frequency Electromagnetic Radiation: A Review and Future

Conclusion

• Most of the WHO recommendations being addressed

• Continued improvement in the quality of exposure systems

• ca. half of lab investigations are replication studies

• increasing number of papers on therapy (e.g. ns electric pulses)