Pengenalan Preparat Hormon

Reproduksi Sintetis

Drh. Cynthia D. Gaina, MTropVSc

17 Maret 2015

Hormone CIDR-B (Controlled internal drug release (CIDR)

CIDR (Progesterone)

CIDRs contain 1.9g of progesterone

In cattle, CIDR-Bs are often used with synchronization protocols

Eazi-Breed CIDR helps to improve the effectiveness of reproduction programs by tightening estrus

synchronization so groups of cows and heifers come into

heat and can be bred in a narrow window.

Groups of cows also can be synchronized to return to estrus after insemination for potential rebreeding in a

desired time frame.

hCG, chorionic gonadotropin (Chorulon,Intervet, Holland)

Chorulon can be used in the following fertility problems in domestic

animals:

- cases of repeated failure of conception in cows and heifers

- induction of ovulation in mares and bitches

- cases of cystic ovaries in cows and heifers

- anoestrus in mares and bitches

- delayed ovulation, prolonged pro-oestrus in bitches

- deficiency in libido in male dogs

http://www.msd-animal-health.co.uk/Products_Public/Chorulon/090_Product_Datasheet.aspx

Species

Indication

Dosage and administration

Cow, heifer

Repeated failure of conception Cystic ovarian disease (anoestrus, prolonged oestrus, nymphomania) Enhancement of luteal function

1500 iu- i.m. or i.v. at AI or mating 3000 iu - i.v. 1500 iu - i.m. 12 days after insemination or mating

Mare

Suboestrus (follicles > 2 cm in diameter) Induction of ovulation

1500 - 3000 iu - i.m. or i.v., repeat after 2 days if necessary 1500-3000 iu - i.m. or i.v. 24 hours before AI or mating

Bitch

Anoestrus Delayed ovulation, prolonged pro-oestrus

500 iu - i.m. or i.v. at first day of oestrus after pretreatment with PMSG 20 iu/kg s.c. daily for 10 days. 100-800 iu / day i.m., repeating treatment until vaginal bleeding disappears. Mate on behavioural oestrus

Male dog

Deficiency in libido

100-500 iu - i.m. twice weekly for up to 6 weeks, but if this is not possible then 100-500 iu i.m. 6-12 hours before mating may give a temporary effect

(Juramate, synthetic prostaglandin)

Cloprostenol is a synthetic prostaglandin analogue structurally related to Prostaglandin F2 (PGF2).

It causes functional and morphological regression of the corpus luteum in cattle.

This effect on the life span of the corpus luteum usually results in estrus 2 - 5 five days after treatment, followed by ovulation with

normal fertility.

Juramate alone will not increase fertility.

Cloprostenol (Estrumate Inter-Ag, Hamilton, NZ)

Cloprostenol

(Lutalyse TM, Pharmacia & Upjohn Company, Pfizer Inc.).

Capriglandin

Prostavet

Fertagyl

Fertagyl is a sterile solution containing 43 g/mL gonadorelin (GnRH; equivalent to 50 g/mL gonadorelin diacetate tetrahydrate)

Endogenous gonadorelin is synthesized by and/or released from the hypothalamus during various stages of the bovine estrous cycle

following appropriate neurogenic stimuli. It passes via the

hypophyseal portal vessels, to the anterior pituitary to effect the

release of gonadotropins.

Synthetic gonadorelin administered intramuscularly or intravenously also causes the release of endogenous LH and FSH from the

anterior pituitary.

Capritocin

CAPRITOCIN Inj. adalah hormon reproduksi yang mengandung oxytocin dalam bentuk larutan injeksi, bekerja dengan cara

merangsang kontraksi otot polos pada uterus dan kelenjar susu

CAPRITOCIN Inj. sangat baik untuk membantu proses kelahiran, memperlancar dan meningkatkan produksi air susu serta

mempercepat penyembuhan kasus metritis dan retensio

secundinarum

PMSG Intervet

the hormone is commonly used in concert with

progestogen to induce ovulation in livestock

prior to artificial insemination.