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Portable HeartPortable HeartAttack DetectorAttack Detector

(PHAD)(PHAD)Characterization PresentationCharacterization Presentation

April 6, 2005April 6, 2005

Technion – Israel Institute of TechnologyDepartment of Electrical Engineering

High-Speed Digital Systems Lab

SupervisorSupervisorDaniel AlkalayDaniel Alkalay

System architecturesSystem architecturesNir GluzmanNir GluzmanAlexei IolinAlexei Iolin

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Did You Know?Did You Know?More than 1.2 million Americans will suffer a heart attack, where about 502,000 of these people will die!340,000 of them in an ER or BEFORE they reach a hospital.

Surviving a heart attack depends on the treatment that is given within the first hour of the heart attack.

Most common reason for treatment delay is patient unawareness.

Source: American Heart Association, 2004 estimation.

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The SolutionThe Solution

Portable HeartPortable HeartAttack DetectorAttack Detector

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AGENDAAGENDAMedical Background

Project Objective

System Block Diagram

NI/FPGA – Pros & Cons

Project Time-Table

Summary

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Medical BackgroundMedical BackgroundECG = Electrocardiogram

Recording of heart’s electrical activity.

Measures rate and regularity.

Used to diagnose diseases.

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Basic ECG complex

Medical Background Medical Background (cont.)(cont.)

R

P

Q

S

T

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Heart attack(Myocardial Infarction)

An event that results in permanent damage to the heart.

myocardium = heart muscle.

infarct = die.

Medical Background Medical Background (cont.)(cont.)

Q-waves and inverted T-waves are two diagnostic wave forms seen in old heart attacks and new heart attacks respectively.

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ST-Elevation (STEMI)Elevation of ST-segment relative to PR or TP segment.

ST-elevation is a sign for coming heart attack (acute myocardial infarction).

Short PR interval - very difficult for computer algorithms to find the isoelectric reference level.

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Develop a system that measures and displays Develop a system that measures and displays RR-RR-raterate, , ST-elevationST-elevation and and alert to wide-QRSalert to wide-QRS..

Implement the system on National-InstrumentImplement the system on National-Instrument (*)(*) Real-Time FPGA development environment using Real-Time FPGA development environment using LabView graphical language. LabView graphical language.

Project ObjectiveProject Objective

(*)(*) website: http://ni.com

PXI-7831R

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System Block DiagramSystem Block DiagramBiosensors

A/D interface

Detection of ECG characteristic pointswith filter-bank

Detection ofRR-rate, ST-elevation, wide-QRS

Abnormalitiesalert

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Filter-Bank Block DiagramFilter-Bank Block Diagram

Input signal is sampled at 360Hz.Input signal is sampled at 360Hz.

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Abnormalities detectionAbnormalities detection(cont.)(cont.)

RR-rate &wide-QRSdetection

ST-elevationdetection

R-detectionDecomposed

Signal

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Abnormalities detectionAbnormalities detection(cont.)(cont.)

R-detection RR-rate & QRS-duration

ST-elevation

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NI/FPGA – Pros & ConsNI/FPGA – Pros & Cons

ProsRapid prototype system.Dedicated hardware and software.

ConsNI development environment is non-conventional – design extraction to other non NI/FPGA environments is NOT possible.VHDL code is hidden from user.

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Project Time-TableProject Time-Table

Study of NI/FPGA & LabView development environment

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Implementation 5

Design verification 2

Limited clinical experiments (optional) 1

Final report and project summary 2

SubjectTime period

(weeks)

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Summary

Patient need for PHAD.

Detailed design of the system.

Pros & cons of NI development environment.

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Questions?Questions?