photoinduced cytotoxicity

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Bilkent niversitesi. Photoinduced cytotoxicity. - PowerPoint PPT Presentation

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  • Fluorescence microscope images of acridine orange (AO) and propidium iodide (PI) stained K562 cells, incubated in full medium with 500 nM sensitizer 3 in dark (the middle panel); irradiated with red LED at 625 for 4 hours followed by 20 hr incubation in dark at 37 oC in the presence of 500 nM sensitizer 3 (right panel); and incubated in dark for 24 hr (left panel). Live cells were preferentially stained with AO (green) and dead cells with PI (red) due to increased cellular permeability. Photoinduced cytotoxicity

  • CNT-derivatization

  • SWCNTs as carries for PDT reagents

  • SWCNTs as carriers for PDT reagentsAFM image of compound 1-SWNT. (B) AFM 3D topographic view. PSIA XE-100E AFM and Multi75AI tip was used in noncontact mode with resonance frequency 75 KHz and force constant 3.0 N/m.

  • SWCNTs as carriers for PDT reagents

  • 670 nmdye DPSBdye DPSB + H+PDT reagents with pH-modulated activity

  • Moores LawBilkent University

    Gordon Moore made his famous observation in 1965, just four years after the first planar integrated circuit was discovered. The press called it "Moore's Law" and the name has stuck. In his original paper, Moore observed an exponential growth in the number of transistors per integrated circuit and predicted that this trend would continue. Through Intel's relentless technology advances, Moore's Law, the doubling of transistors every couple of years, has been maintained, and still holds true today. Intel expects that it will continue at least through the end of this decade.

    Gordon Moore

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