(Continuedfrm page 1684)

The Prediction of Ionospheric Conditions. G. S.Ivanov-Kholodny and A. V. Mikhailov. Reidel, Dor-drecht, 1986 (U.S. distributor, Kluwer, Norwell, MA).x, 168 pp., illus. $49.95. Geophysics and AstrophysicsMonographs. Translated from the Russian edition (Len-mgarad).

edings of the 1985 Intemational Sympo-sium on Lepton and Photon Interactions at HighEnergies. (Kyoto, Aug. 1985.) Michiji Konuma andKasude Takahashi, Eds. Published by the OrganizingCommittee, Yukawa Hall, Kyoto University, Kyoto,1986 (U.S. distributor, Taylor and Francis, Philadel-phia). viii, 977 pp., illus. $81.Remote Sensing for Resources Development

and Environmental Management. M. C. J. Damen,G. Sicco Smit, and H. Th. Verstappen, Eds. Balkema,Accord, MA, 1986. Vol. 1, Visible and Infrared Data,Microwave Data, Spectral Signatures of Objects, Renew-able Resources in Rural Areas. xvi pp. +pp. 1-548, illus.Vol. 2, Non-renewable Resources, Hydrology, HumanSettlements, Geo Information Systems. x pp. + pp. 549-956, illus. $106, with vol. 3. From a symposium,Enschede, The Netherlands, Aug. 1986.Research in Biology at Private Undergraduate

Institutions. Laura L. Mays Hoopes et al., Eds. CollegeResearch Association of Biologists, Council on Under-graduate Research, Tucson, AZ, 1986. viii, 303 pp.Paper, $30.Response Times. Their Role in Inferring Elemen-

tary Mental Organization. R. Duncan Luce. Clarendon(Oxford University Press), New York, 1986. xvi, 562pp., illus. $8.75. Oxford Psychology Series, 8.Ringmakers of Satum. Norman R. Bergrun. Pent-

land, Edinburgh, 1986. xii, 116 pp., illus. $42.50.Safety Evaluation of Drugs and Chemicals. W.

Eugene Lloyd, Ed. Hemisphere, New York, 1986. xviii,487 pp., illus. $59.95. Based on a symposium, Ames, IA,June 1981.

Safety of Computer Control Systems 1986. (SA-FECOMP '86.) Trends in Safe Real Time ComputerSystems. W. J. Quirk, Ed. Published for the InternationalFederation of Automatic Control by Pergamon, NewYork, 1986. viii, 193 pp., illus. $45. From a workshop,Sarlat, France, Oct. 1986.Spinoza and the Sciences. Marjorie Grene and

Debra Nails, Eds. Reidel, Dordrecht, 1986 (U.S. distrib-utor, Kluwer, Norwell, MA). xx, 336 pp. $54.50. Bos-ton Studies in the Philosophy of Science, vol. 91. Basedon a symposium.

Structural Analysis Systems. Software-Hardware-apability-Compatibility-Applications. A. Niku-Lari

Ed. Pergarnon, New York, 1986. Vol. 4, CAD/CAMand Structural Analysis in Industry. xii, 272 pp., illus.$57.50. Vol. 5, Finite, Boundary Element an ExpertSystems in Structural Analysis. xii, 203 pp., illus. $44.From a conference, Paris, Oct. 1986.Surface Waves in Plasmas and Solids. S. Vuko-

vic, Ed. World Scientific, Singapore, 1986 (U.S. distrib-utor, Taylor and Francis, Phifadelphia). xvi, 692 pp.,illus. $72. From a conference, Ohrnd, Yugoslavia, Sept.1985.Symbiosis. An Introduction to Biological Associa-

tions. Vernon Ahmadjian and Surindar Paracer. Pub-lished for Clark University by University Press of NewEngland, Hanover, NH, 1986. xii, 212 pp., illus.

Synopsis of the Nomenclature of the Fixed Stars.Helmut Werner and Felix Schmeidler. WissenschaftlicheVerlagsgesellschaft, Stuttgart, F.R.G., 1986. xii, 510pp.,illus.DM 138. Text m Gennan and English.Targeting of Drugs with Synthetic Systems.

Gregor Gregoriadis, Judith Senior, and George Poste,Eds. Plenum, Ntw York, 1986. viii, 299 pp., illus.$52.50. NATO Advanced Science Institutes SeTries A,vol. 113. From an institute, Cape Sounion Beach,Greece, June 1985.Theories of Human Evolution. A Century of De-

bate, 1844-9144. Peter J. Bowler. Johns Hopkins Uni-versity Press, Baltimore, 1986. xvi, 318 pp., illus.$32.ZO'The Three-Body Force In the Three-Nucleon Sys-

tem. B. L. Berman and B. F. Gibson, Eds. Springer-Verlag, New York, 1986. xii, 530 pp., illus. $48.40.Lecture Notes in Physics, 260. From a symposium,Washington, DC, April 1986.Tradeoff. Imperatives of Choice in a High-Tech

World. Edward Wenk, Jr. Johns Hopkins UniversityPress, Baltimore, 1986. xiv, 238 pp. $19.95.

Viral Hepatitis. F. Callea, M. Zorzi, and V. J. Des-met, Eds. Springer-Verlag, New York, 1986. x, 110 pp.,illus. $37.40. Proceedings in Life Sciences. From amecting, Brescia, Italy, 1985.

i688

POSITIONS WANTEDAnatomist, Ph.D. seeking tenure-track position in anat-omy or biology department. Four years experience asdirector of gross anatomy course in medical school.Ongoing NIH and private foundation research grantsupport in neurobiology. Box 36, SCIENCE. X

Bioengner/Physiologist, Ph.D. Publications, patents,30 years academic, industrial, government biomedicalR&rD experience, includingbasic and applied research,dinical investigation, tea g, product development,administation, teaching, product development, adminis-tration, patent litigation and contract management. De-sire freeLane professional assignments, long/short term.P.O. Box 9106, La Jolla, CA 92038. Telephone: 619-456-2565. X

Biophysical Chemist with Organic Badkground,Ph.D. (U.K). Many years experience plus pubTicationsin use of liposomes as model membranes or drugintcractions and functional reconstruction of membraneproteins. Familiar with biochemical, spectroscopic(EPR, fluorescence), and synthetic techniques. Literatewith good knowledge of German. Seeks challengingindustrial, academic, or administrativewriting positions.Box 29, SCIENCE. X

Entomologist, Ph.D., 25 years' international experiencein biological control, quarantine, biosystematics, excel-ent crdentials, desires position. Box 42, SCIENCE.

3/27; 4/3Foreign M.D. with background in molecular biologyresearch, seeking postdoctoral or research associate posi-tion. Box 43, SCIENCE. X

POSITIONS OPEN

AREA EXTENSION AGENT, Water Resours,Minnesota Extension Service, University ofMinneso-ta (UM). A multicounty water resources agent in Lakeand Cook counties. Responsible for developing educa-tional programs dealing with the broad range of waterresource issues.

Required qualifications: bachelor's degree with em-phasis in hydrology, geology, environmental engineer-mg, or a related water resources area and 5 years ofexperience in the water resources area or a master'sdegree with the same emphasis.

ipplication deadline: 10 April 1987. Contact: Exten-sion Personnel, 260 Coffey Hail, U of M, St. Paul,MN 55108. Tdelphone: 612-624-3717.

The Univerity of Minnesota is an Equal OpportunityEducator and Emklcrye and pecficaUlly invitcs and encour-ages applictiom women and minonties.

The Department of Physiology, Marshall UniversitySchool ofMedicine, invites applications for the positionofASSISTANT PROFESS OR (tenure track) in physi-ology. This 12-month appointment can begin as early asJuly 1987. Candidates must have a Ph.D. in physiology,and at least 2 years of postdoctoral experience in neuro-physiology. The candidate must be committed to excel-

to the development of a competi-tive, basic research program. Teadiing responsibilitiesare in the School of Medicine and m the GraduateProgram in Biomedical Sciences. Applicants should sendcurnculum vitae, representative publications, a summaryof previous and proposed research, and three letters ofrecommendation to: Dr. L. Howard Aulick, Depart-ment of Physiology, Marshall University School ofMedicne, 1542 Spring Valley Drive, Huntington,WV 25706-2901. Applcations should be submitted by30 April 1987.Mashal University is an Equal Opportuni-ty/Affirnative Action Employer.

ASSISTANT PROFESSOR, VERTEBRATE POP-ULATION BIOLOGY. Available fall 1987. Ph.D.required. Teach population biology and/or biostatistics,general zoology; direct graduate students; maintain ac-tive research program. Special consideration may begiven to wetlands biologists. Curriculum vitae, statementof research goals, three letters of recommendation mustbe received by i May 1987. Send to: Dr. Gary W.Childers, Search Committee Chairman, DepartmentofBiological Sciences, Box 814, Southeastern Louisi-ana University, Hammond, LA 70402. An EqualOpportunity Employer.

Department of Physiologca Chemistry-University

of iM adison. An ASSISTANT PROFES-SOR position will be available 1 September 1987 for aperson with strong biochemical research and teachingintercsts. The abilities of the applicant are more impor-tant than the particular area of research interest. Depart-ment faculty have active basic and applied researchprograms in molecular biology, developmental biology,hormones, protein chemistry, membranes, lipids, and

metabolism, as well as teaching responsibilities for du-ates, medical and health science students. Applicantsshould have at least 2 years of biochemical postdocresearch experience. They should submit curriculumvitae, bibliography, letters of reference from three per-

sons knowledgeable of the candidate's research or teach-

ing abilities, and a one- or two-page statement of futurercsearch interests to: Dr. James Dahlberg, Chairman,

Faculty Search Committee, 587 Medcal ScienceBuilding, 1300 Univcrsity Avenuc, Madison, WI53706 by 1 June 1987. The Univeity ofWisconsin is anEqual Opportunity/AffitwatieAaton Etloyefr.

ASSISTANT PROFESSOR, PHYSIOLOGY. Full-time, tenure-track. The Department of Basic Science,California Colege of Podiatric Medicine, seeks a

Ph.D. to coordinate and teach a course in human physi-ology. Ph.D. in physiology desirable; however, candi-dates with background in endocrinology or neurosci-ences are welcome to apply. Applicant must have a strongcommitment to teaching. Starting salary commensuratewith experience. A complete curriculum vitae and thenames of three references should be sent by 15 April1987 to: BarbaraM. Kriz, Ph.D., Chairperson, SearchCommittee, Department of Basic Science, CaliforniaColle of Podaatric Medicine, P.O. Box 7855; SanFrancsco, CA 94120. AnAffirmativeActionl/Equal Op-portunity Employer.

SCIENCE, VOL. 235

PersonnelPlacement

SCIENCE publishes each Friday, except the last Fridayof the year. Advertising is accepted only in writing; noabbreviations. Any deadline in ad must be at least 2weeks after date of issue in which ad appears. Also,personnel advertising is accepted only with the under-standing that the advertiser does not discriminateamong applicants on the basis of race, sex, religion,age, color, national origin, handicap, or sexual prefer-ence.

UNE CLASSIFIED ADVERTISING DEADUNES:Thursday, 2 weeks prior to issue date (mailed on issuedate).

POSiTIONS WANTED: 40¢ per word, plus $4 for use ofbox number, per week. $10 minimum, per week.Prepayment required. This rate is available only toindividuals seeking jobs.

UNE CLASSIFIED (POSMONS OPEN, COURSES,FELLOWSHIPS, MARKETPLACE, and so forth):$35.00 per line; $350 minimum, per week (minimumcharge covers one inch on a single column; one inchequals 10 lines of 52 characters and spaces per line).No charge for use of box number. No agency commis-sion for ads less than 4 inches. No cash discount.Prepayment required for all foreign ads. Purchaseorders and/or cover letter including billing addressrequired for all other advertising.

Structure ad copy on a separate page, on lines of 52characters and spaces. Include any desired heading.Each line of heading and/or extra spaces, and allpartial lines are counted as full lines. To calculate cost,multiply total lines x $35.00 = total cost of ad.

Send copy for all Positions Wanted ads and UneClassified ads less than 1/6 page in size (39 lines) to:

SCIENCE Classfied Advertising1333 H Street, NW, Room 940

Washington, DC 20005Toelphone: 202-3264555

Send copy for Fractional Display ads, 1/6 page andlarger, and all Marketplae ads to:

Scher7wo , Inc.15-15 Broodwav

New York, NY103Telphone: 212-730-1050

Blind ad replies should be addressed as follows:

Box (give number)SCIENCE

1333 H Street, NWWashington, DC 20005

POSITIONS OPEN

ASSISTANT PROFESSOR OF DEVELOPMEN-TAL BIOLOGY-TENURE-TRACK Pan AmericanUniversity, Edinburg, Texas. A tenure-track position atthe assistant professor rank is open (subject to availabilityof funds) beginning 1 September 1987. The salary

20 per 9-month academic year)depends on the qualifications and experience of thesuccessful candidate. Qualifications mdude: earnedPh.D. from an accredited institution of higher learning,capable of teaching embryology, and at least two of thefolowing: anatomy and physiology, comparative anato-my, mammalian physiology. The successful candidatewill be expected to develop a graduate course in his/herspecialty and participate in the eneral biology program.Normal loads in the biolog departmcnt arc 12 credithours (15 contact hours). e successful candidate willbe expected to obtain extemal funding, develop andmaintain an active research program and participate indirecting the thesis research of students leading to theM.S. in biology. Closing Date: 15 April 198T Appli-cants should submit curriculum vitae, copies of recentrepresentative publications, and arrange to have threeletters of reference sent to: Dr. T. C. Aison, Chairmanofthe Search Committee, -1210 West University, PanAmerican Univmrsity, Edinburg TX 78539. PanAmerican Univenity is an Equa O nityAfrtAction Employer.

ASSISTANT PROFESSORPLANT MOLECULAR BIOLOGIST

Department of biology is seeking applicants for a tenure-track plant molecular biology position. We seek anindividual who wrill complement and strengthen existingplant biology programs. Applicants with bacdrounds intheeof plant-microbe interactions, plant virology, orphotosynthesis are encouraged; however, we welcomeapplicants with interests in other areas of plant molecularbiology or molecular genetics. The expected teachingload iS about one course/quarter, to consist of a mix ofundergraduate and graduate courses and seminars. Toapply, send application with curriculum vitae, statementof research interests, and three letters ofrecommendationby 15 May 1987 to: Dr. Neal Van Alfen, Departmentof Biology, Utah State University, Logan, UT84322-4500. AffirmativeActionlEqual Oppounity Em-plyecrASSISTANT/ASSOCIATE PROFESSOR: Tenuretrack, must have expertise in NMR spectroscopy ofheartand brain. Will coordinate the physiological aspects ofthe NMR research on humans and animals being carriedout at the University of New Mcxico center for Non-Invasive Medical Diagnosis. Expected to develop anindependent research program and provide quality teach-ing of medlical and graduate students. Deadline: 1 July1987. Submit currculum vitae, statement of rchinterests, three references to: Dr. Albert Ratner, ActingChair, Ph siolo Department, University of NewMcxico, School of Medicne, Albuquerque, NM87131. AffirmativeAcionlEqual Opportunity Employer.Morris College, a private 4-year liberal arts college inSumter, South Carolina, is sceking applicants to fill thefollowing positions.ASSISTANT/ASSOCIATE PROFESSOR OF BI-OLOGY, to teach introductory and advanced biologycourses induding botany, genetics, and ecology. Ph.D.mchemistry preferred, master's degree acceptable.ASSISTANT/ASSOCIATE PROFESSOR OFCHEMISTRY, to teach general chemistry and physicalsciences. Ph.D. in chemistry preferred, master's degreeacceptable.ASSISTANT/ASSOCIATE PROFESSOR OFMATHEMATICS, to teach introductory and advancedmathematics courses, methods in the teaching of mathe-matics. Master's degree in mathematics required.Submit letter of application, three letters of recommen-dation and official academic transcripts to: PersonnclOfficer, Morris College, Sumter, SC 29150. Deadlinefor accepting application is 17 April 1987. An EqualOpportunitylAffirmativeAcion Empv er.

BIOMEDICAL ENGINEER Eastern manufacturerof patient monitoning systems seeks individual for con-ceptualdesin, clinical/field testing, and custorner coor-

seek life science rescarch or clinical engi-neerng expenence. Submit r6sum6 to: Box 41, SdI-

The Department of Microbiology, at The OhioStatc University invites applications or a tenure-trackASSISTANT PROFESS OHP IN VIROLOGY.Candidates with interests in an aspect of viral disease ordisease prevention are particularly encouraged to apply;bowever, candidates with expertise in any viral systemwill be considered. The successful candidate must havedemonstrated their research potential by recent publica-tions and will be expected to develop and maintain anindependent research program, teach an undergraduatecourse in general virology, participate in the generalteaching responsibilities of the Department and traingraduate students. Candidates shoufd have a Ph.D. de-gree and at least 2 years of postdoctoral experience.

Candidates should submit curriculum vitae, a summa-ryof research plans and names of three references to: Dr.nieN S. Zwilling, Chairman, Virology Search Com-

mittee, Department of Microbiology, College of Bio-ogical Sciences, The Ohio State University, 484 West12 Avenue, Columbus, OH 43210. The postion isavailabe starting aut 1987; applications receivedbefore 15 Aprif 1987 will be considered in the firstinstance; however, applications will be accepted until theposition is filled.

The Ohio State Univer it an AffirnativeAction/EqualOpportunity Emplqoyr.ASSISTANT/ASSOCIATE PROFESSOR, tenure-tradc to begin 1 July 1987. Interest in microbial patho-genesis is preferred. Duties: teach medical bactenologyto medical and graduate students; develop an indepen-dent research program. Send curriculum vitae and namesof dtree references by 1 May 1987 to: Dr. R S.Desowitz, Chairman Search Committece, DepartmentofTropical Medicine and Medical Microbiolo, Uni-versity of Hawaii School of Mcdicine, 3675.1KautaAvenue, Honolulu, HI 96816. Equal Opportunity Em-ployer.

ASSISTANT RESEARCH PHYSICISTOR ASTRONOMER

EUV INSTRUMENTATION AND PHYSICSThc Space Astophysics Group at the Univerity of

California Bcrkely has an opening for an assistantresearch physicist or astronomer. The position is for 2years beginning 1 June 1987 with a high likelihood ofcxtension. The responsibilities will indude the testing ofgratings, collimators, and other EWV optical compo-nents for NASA's Extreme Ultraviolet Explorer Sateite.The position will also require theoretical and analyicwork in the design and testing of novel instrumentationfor use in the EUV.A Ph.D. in physics or astronomy with experience in

space instrumentation is required. Laboratory experiencewith x-ray and EUV gratings, spectrometers, detectors,and other testing and calibration techniques is required.Send r6sume and three letters of recommendation by

30 April 1987 to:Dr. Roger F. Malina

Space Sciences LaboratoryUJniversity of CaliforniaBerkeley, CA 94720

The Univeri of Calinia an Equal OpportuntlylAffirmativeAction Employer.

BIOMEDICAL ENGINEERING. Worcester Poly-technic Institute (WPI) is continuing to expand itsbiomedical engineering program and a new tenure-trackfaculty position is available. Although the level of ap-pointment and area ofspecialization are open, preferencewill be given to senior-level applicants in either MagneticResonance Imaging (MRI) or the in vivo application ofmagnetic resonance. Clinical and research magnetic reso-nance facilities are available at the Massachusetts Biotech-nology Research Park in Worcester and strong collabora-tive ties with the University of Massachusetts MedicalSchool in Worcester exist. Other areas of particularinterest are: biomechanics, biomaterials, biosensors, ap-

plied neurophysiology, and application of mathematicsand system anal sis techniques to physiology. Candidateswill be expected to develop a vigorous research programwith external funding, and be committed to qualityteaching. Applications should include curriculum vitae,statements of research and teaching interests, repre-sentative reprints/preprints, and names of three or morereferences to be sent to: Dr. Robert A. Peura, Biomedi-cal E3ngineen, WPI, Worcester, MA 01609. Tele-phone: 617-7%3-1447. WPI is an Affirmative AtionlEqual Opportunity Emsployer.

27 MARCH I987

ASSOCIATE RESEARCH SCIENTISTS ANDPOSTDOCTORAL RESEARCH SCIENTISTS

Study cis sequence and transacting protein regulation ofeukaryotic transcription within a gene family. Send cur-riculum vitae and names of references to: Dr. Phili,Feiselaon, Institute of Cancer Research, ColumbiaUniversity, 701 West 168 Strect, New York, NY10032. Columhia University is an Equal Opportunity/Affirmative Action Employer.

CELL BIOLOGY AND PHYSIOLOGYWASHINGTON UNIVERSITYSCHOOL OF MEDICINEST. LOUIS, MISSOURI

The Department of Cell Biology and Physiology,Washington University School of Medicine, St. Louis,Missouri, is expanding its commitment to research in thefollowing areas: (i) membrane protein function andbiogenesis; (ii) assembly, fimction, and movement ofintracellular organelles; (iii) cell motility and contractil-it; and (iv) cell-cell and cell-matrix interactions. Individ-uals who employ novel biophysical and recombinantDNA methodologies are especially encouraged to apply.Tenure-track positions are available for successful candi-dates who will be exped to develop an independentresearch programan to participate ithe traiing ofmedical and graduate students. Ptease submit curriculumvitae and the names of three references to: Dr. PhilipStahl, Department of Cell Biology and PhysioloagyWashington Univcrsity School of Medicne, 660South Euclid Avenue, St. Louis, MO 63110. AnAffirmative ActionlEqual Opportunity Employer.CELL AND MOLECULAR BIOLOGIST IN

NEPHROLOGYAdjunct Assistant Professor I level position available.Requires Ph.D. with at least 4 years of postdoctoralexperience in cell biology of renal and uroepithelial cellswith particular reference to control of cell growth.Expertise in establishment of primary cultures and devel-opment ofmethods for enhancing differentiated functionin vitro. Experience in isolation, purification, and biolo-gy of growth factors. Experience in molecular biologyand recombinant DNA technology. Instruct renal fellowsin laboratory techniques and supervise research projects.Experience m general laboratory management. Demon-strated independent research experience by scientificpublications. Salary: $34,600 per year. UCLA is anEqualOpportunity Etlkyer. Send resume to: Leon G. Fine,M.D., Professor and Chief, Division of Nephrology,UCLA School ofMedicine, Los Angeles, CA 90024-1736.

UNIVERSITY OF QUEENSLANDEqual Opportunity in Etmloyment is University Policy

DIRECTORCOMMUNITY NUTRITION PROGRAM

Applications are invited for the position of Director,Community Nutrition Program.The appointee will be responsible for a master's course

in community nutrition conducted by the University ofQueensland in collaboration with the Institute ofNurtition, Mahidol University and Khon Kaen Uni-versity, in Thailamd, and Universiti Kebangsaan Ma-laysia. The appointee, who will take part in other teach-ing and research activities, will be expected to haveexperience and qualifications in one of the behavioral,health, or agricultural sciences relevant to communitynutrition in developing countries, be committed to aninterdisciplinary approach to training community nutri-tionists, preferably have experience of "marketing" edu-cational programs, have been involved in commrunityprojects, possess good human relations, and have con-tacts in the international nutrition area preferably, butnot essentially, in Southeast Asia.Appointment will be 3 or 5 years from date of

appointment, and will carry university status, title andsalary of Reader/Professor, currently A$49,268 toA$58348 per annum with clinical loading ofA$10,433 ifapplicable; terms and conditions to be negotiated. Refer-ence No. 12887.

Further information may be obtained from: the retir-ing Director, Associate Professor M.S. Gilliland, Uni-versity of Queensland, St. Lucia 4067, Queensland,Alstralia. Telephone: 61-07-377 3837.

Applications, stating earliest date available for com-mencement of duties to: Director, Personnel Services,Univcrsity of Qucensland, St. Lucia 4067, Queens-land, Australia by 29 May 1987.

PERSONNEL PLACEMENT 1689

POSITIONS OPEN POSITIONS OPEN

The Drug Metabolism Department of Smith Kline & FrenchLaboratories, located in suburban Philadelphia, Pennsylvania, isseeking a Postdoctoral Scientist to perform basic research in an arearelevant to Drug Metabolism. This position offers the opportunity tointeract with senior members of the department to facilitateprofessional growth. Candidates will report research results within thecompany and at national scientific meetings and are encouraged topublish these results in leading trade joumals.Our postdoctoral positions are normally of two years duration.The successful candidate is required to have:* a Ph.D. in Biochemistry, Pharmacology or related area.

* experience in the preparation of subcellular fractions for studies ofxenobiotic metabolism.

* working knowledge of bioanalytical techniques such as GC andHPLC.

* demonstrated ability to apply multi-disciplinary techniques tohypothesis testing.

We offer an excellent compensation, benefits and relocation packageas well as opportunities for personal and professional growth. Pleaseforward your C.V. and the names of three references to: Robert F.Obst, R&D Senior Employment Consultant, SmithKline BeckmanCorporation, 1560 Spring Garden Street, Philadelphia, PA 19101. Weare an Equal Opportunity Employer, M/F/H/V.

The Molecular Biology Research Unit of The Upjohn Company is cur-rently building a group to work on molecular approaches to neurobiol-ogy. The successful Research Associate candidate will have a BS or MSdegree plus at least one year of research experience in recombinantDNA techniques. This is a career position. A strong research back-ground in cDNA/gene cloning and DNA sequencing is necessary. Aninterest in working in the area of diseases of the central nervous systemis important, and cns research experience and background will be astrong plus. Familiarity with in vivo expression system, such as Xeno-pus oocytes and transgenic models is preferred but not required. Inaddition to continued work using the candidates' expertise in molecularbiology, the work will also include collaborative projects with other bio-technology units and the CNS Research group at Upjohn.Kalamazoo is a medium-sized Southwestern Michigan community withimmediate access to a rich mix of cultural, educational and recreationalpursuits including numerous lakes and a four-season climate. Upjohnoffers the opportunity for career growth, a competitive salary commen-surate with experence, a comprehensive benefits program and reloca-tion assistance.For confidential consideration, please call, from outside of Michigan.toll free 1-800-253-8600, ext. 3-6767, (inside Michigan call collect 616-323-6767) to request an employment application be sent to you imme-diately. Please refer to ad number 1444-A when calling.

S . 0 - 0

An Equal Opportunity Employer M/F

Protein EngineerTriton Biosciences Inc., an entrepreneurial subsidi-ary of Shell Oil Company, is an emerging biotech-nology company engaged in the development ofdiagnostics and therapeutics for human health care.

Our company is built upon a strong base of researchexpertise, solid support, and responsive management.

An excellent opportunity exists for an innovative re-

searcher in our Protein Chemistry Department. Thesuccessful candidate will apply molecular modelingtechniques to the design of protein and peptideanalogs which may have utility as cancer therapeuticagents. Candidates should have a Ph.D. with 3-5years experience and a strong background in proteincrystallography and computer graphics.

Triton is located in the San Francisco Bay Area andoffers competitive salaries and benefits. For promptconsideration, please forward your C.V. along withsalary requirements and the names of three refer-ences to: Triton Biosciences Inc., Box PE, 1501 Har-bor Bay Parkway, Alameda, CA 94501. An EqualOpportunity Employer.

Triton Biosciences Inc.

The Molecular Biology Research Unit of The Upjohn Company is cur-rently building a group to work on molecular approaches to neurobiol-ogy. The successful candidate will have a Ph.D. in biochemistry, molec-ular biology or related discipline. Significant research accomplishmentwith evidence by publications is important. This position will involve atwo-year appointrment. A strong research background in cDNA cloningand DNA sequencing is necessary. An interest in working in the area ofdiseases of the central nervous system is important and CNS researchexperience and background will be a stronger plus. Familiarity with invivo expression system such as Xenopus oocytes and transgenicmodels is preferred but not required. In addition to continued work us-ing the candidate's expertise in molecular biology, the work will alsoinclude collaborative projects with other biotechnology units and theCNS Research group at Upjohn.Kalamazoo is a medium-sized Southwestern Michigan community withimmediate access to a rich mix of cultural, educational and recreationalpursuits including numerous lakes and a four-season climate.For confidential consideration, please call toll free 1-800-253-8600, ext.3-6767, (inside Michigan call collect 616-323-6767) to request an em-ployment application be sent to you immediately. Please refer to adnumber 21051-F when calling.

S . - . - M0

An Equal Opportunity Employer M/F

AcceleratorPhysicists

The Lawrence Berkeley Laboratorywill shortly enter the constructionphase of the 1-2 Ge SynchrotronRadiation Source Project. Thesource consists of a 1-2 GWV elec-tron storage ring fed by a 15 GeVsynchrotron and a 50 MeW/ linac.We invite applications for 2 posi-tions within the AcceleratorSystem Group for.

Staff Scientist 11The incumbent will assist infinalizing the parameters of thevarious components of the 1-2GWV Synchrotron Radiation Source.Will participate in all aspects ofSource commissioning and willplay an active role in developingthe Source to its fullest potential.The successful candidate musthave demonstrated experience inaccelerator physics and have aproven track record in design orutilization of circular or linearaccelerators. Must have specificexperience in one or more of thefollowing fields: rf design, magnetdesign, diagnostics, lineardynamics, control systems, feed-back systems. Prefer a PhD inPhysics.Staff Scientist IIIReporting to the Head of the Accel-erator Systems Group, the incum-bent will bear primary respon-sibility for defining the detailedspecifications of the storage ringfor the 1-2GV SynchrotronRadiation Source. Will lead inte-gration of the subsystems of thelight source. Will play a lead rolein the commissioning of thesource. Will provide technicaldirection and supervision to pro-ject staff.

The successful candidate will bean experienced AcceleratorPthysicist, with proen expertise inthe design and commissioning ofelectron storage rings or electronsynchrotrons. Will have particularexperience in at least one of thefollowing fields: rf (design, coupledbunch instabilities), magnetdesign, diagnostics, controlsystems, feedback systems.

To apply, send 2 copies of cur-riculum vitae, representativepublications and the names andaddresses of three references to:Lawrence Berkeley Laboratory,#1 Cyclotron Road, EmploymentOffice 90-1042, Berkeley, CA 9420.Refer to Job #N/4091 for StaffScientist II and Job #A/4090 forStaff Scientist Ill. An Equal Oppor-tunity Employer. M/F/H.

LAWRENCEBERKELEY

LABORATORY

U~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

RESEARCHASSOCIATESProteinChemistry/Immunology

An industry leader in advancedbiotechnology, Amgen develops pro-ducts in the human health care areaWe have immediate opportunities forResearch Associates to provide sup-port in our Protein Chemistry andImmunologyDeparments inthecharac-terization of natural and recombinantproteins.

PROTEIN CHEMISTRYQualified candidates for the protein chemistry positons should have a BS/MS inChemistry, Biochemistry, or a related field. Experience in the manipulation andcharacterization and purification of proteins is essential. Additional experience inelectrophoresis and HPLC is desirable. (Dept. 240a)

IMMUNOLOGYQualified candidates should have a BS/MS in Immunology, Biochemistry or a relatedfield, and experience in mammalian cell culture as well as immunoassaydevelopment (Dept. 125)

Amgen is located in an attractive community about an hour northwest of LosAngeles and offers a stimulating and challenging scientific environment as wellas excellent compensation and benefit programs Applicants should direct aresume and the names of 3 references to:

Recruitment (Specify Dept. #)

AMGEN1900 Oak Terrace LaneThousand Oaks, CA 91320

..I.

Eqs -W E

Abbott Laboratories' breakthroughs in research and development have won usthe undisputed world leadership position in medical diagnostics. The potentialof this field is tremendous, a trend which industry experts predict will continueto grow. As the fastest growing division of our S3.8 billion corporation, our

Deagntics Division is aggressively forging ahead, creating the following positions.

M.S./Ph.D. Genetics/Molecular BiologyThese individuals will work with an interdisciplinary team in the research anddevelopment of nudeic acid probes for dincally useful diagnostic assays. Qualifiedcandidates will have either an M.S. or a Ph.D. with at least 1-2 years postdoctoraltraining or equivalent.Ph.D. Biochemists/ImmunochemistryThese individuals will be invoied in protein purification and immunoassaydevelopment in HTLV Ill and Hepatitus B research areas. You will need a Ph.D.in Biochemistry or Immunology, plus at least 2 years related postdoctoralexperience. We would prefer a strong immunological background with somesupervisory experience.Voted one of the five best managed companies in 1986 by Dun's Magazine,Abbott provides excellent salaries and comprehensive benefits including profitsharing and stock retirement plan. We are located in an attractive suburbanarea, just 30 miles north of Chicago. For confidential consideration, sendyour resume with salary history to: Stephanie Mondello, Dept. S/3-27.Abbott is an affirmative action employer.

MEETNG BOUND?Abbott Representatvs will be atthe FASEB meeting In Washington,DC on March 30. Ifyou will not be able to attend, send your resumeto Sepanie Mondello.

ABBOTTABBOTT PARK IL 60064"He-alth Care VWordwide'

mm

POSITIONS OPEN

BIOTECHNOLOGY, RESEARCH ASSISTANT.A challenging position for a protein chemistry specialistis open at the Rockefeller University Biopolymer Facili-ty. Successful applicants will have a B.S. or M.S. andexperience in peptide or DNA synthesis. The facility ispresently equipped with two gas-phase sequencers, apeptide thesizer, and a DNA synthesizer. Salary nego-tiabk, based on qualifications and experience. Excellentbenefits and beautiful working environmcnt. Send resu-mc and letters of recommendation to: Personnel Office,Roceeller Univcrsity, 1230 York Avenue, NewYork, NY 10021. An Equal Opporunity EmploVer.

CHAIRDEPARTMENT OF PHYSICS

EMORY UNIVERSITYApplications and nominations arc invited for the posi-

tion of Professor and Chair ofthe Department ofPhysicsof Emory University. We seek candidates with distin-guished records in research and tcaching, with provenadministrative skills, and with leadership ability to guidcthe Department during a peniod of rapid growth in size,quality, and reputation. The-department, which now hastwelve faculty members, will have the opportunity to addat least five to six new faculty, at both junior and seniorranks, over the next five years. It will movc into highquality space in a new research building in thc summer of1989.The Dcpartmcnt is committed to Emory's liberal arts

tradition, with strong commitment to teaching and tophilosophical breadth; yet it also recognizes the needwithin that context to build graduate training and re-search strength in a few carefuly chosen areas. Growth isexpected to complemcnt the present cmphascs in con-densed matter physics and biophysics, and offers thepossibility of ad7ding a third area of specialization yt tobe chosen.

Persons interested in being considered or in nominat-ing candidates please contact Billy E. Frye, Chair,Physics Scarch Committee, 305 Adm isrationBuilding, Emory Univcrsity, Atlanta, GA 30322.Applications and nominations will be reccived until 1December 1987 or until a suitable candidate has becnfound. Emoty is an Equal OpporunitylAffirmatie AaionEmployer.

CHAIRPERSON, Department ofAnatomy, WestViginia University, seeks a chairperson for its depart-ment of anatomy. The successful candidate must aveM.D. and/or Ph.D. degree, should have a record ofscholarly academic and rescarch achievements, and prov-en leadership ability. We are searching for an individualto administer the rigorous teaching and research missionsin the department and to plan and implement progransin cell and molecular biofogy that will interface with anewly established Regiona[Cancer Center. Applicantsshould send curriculum vitae and names and addrese ofthree references to: Nathaniel F. Rodman, MD., De-partment of Pathology, West Virgnia University,S;chool of Medicne, Morgantown, WV 26506, notlater than 18 May 1987. West Virginia Unierity is anAffirmat Action/Equal Opponuty Emplyr.

CHAIRPERSON DEPARTMENT OFVETERINARY ANATOMY

COLLEGE OF VETERINARY MEDICINETHE OHIO STATE UNIVERSITY

The Ohio State University College of VeterinaryMedicine invites nominations or applications for theposition ofChairperson ofthe Department ofVeterinaryAnatomy. An excellent opportunity exists for growth inthis department with young faculty, positions to befilled, and new office, teaching, and research facilities.The candidate must possess a doctoral degree, demon-

strated excellence in research and teaching, enthusiasm,and leadership ability. The responsibilities indude ad-ministration of the professional and graduate teachingand research programs in veterinary anatomy. Activeparticipation in teaching and research is also expected.

Applications should be accompanied by curriculumvitae and the names of three references. Contact: Dr.Philip W. Murdick, Chair, Search Committee, Col-lege of Veteri y Medicine, 1900 Coffey Road, Co-humbuas, OH 43210. It is suggested that applications besubmitted as soon as possible. Applications will beaccepted until the position is filled.The Ohio State Umversrt is anAffirmaivAction/Equal

Opportunity Employer.

I692

CHAIRDEPARTMENT OF BIOLOGY

EMORY UNIVERSITYEmory University is inviting applications or nomina-

tions for the position of Professor and Chair of theDepartment ofrBiology. We seek candidates with distin-guished records in research and teaching, with adminis-trative ability, and with the lcadership qualitics that willbe needed to help the biology department in its cffort tonse quickly to national distinction. The department,which now has thirteen faculty members representingfour subdisciplines, will have the opportunity to add atleast eight new faculty members over the next 5 years.This growth will indude both junior and senior appoint-ments, and may indude a major endowed chair if asuitabkc candidate is identified. Construction of a newresearch building has just be that will enable thedepartment to move into high qualit research spaceduring the summer of 1989.The Department is committed to a liberal arts tradi-

tion, with strong commitment to teaching and tobreadth, yet recognizes the need within that context tosekct a few carefully chosen fields for emphasis. In thisregard the future of the department could be furtherstrengthened by a divisional orgaization of the biologi-cal seiences, incuding the basic health science depart-ments. This is now under consideration and could permitbuilding ofgreater foci ofstrength in graduate educationand rcsearch.

Persons interested in being considered or in nominat-ing candidates, please contact: Billy E. Frye, Chair,Biology Search Committee, 305 AdministationBuildani Emory University, Atlanta, GA 30322.Applications and nominations will be received until 1December 1987 or until a suitable candidate has beenfound. Emoy is an Equal OpporunityLAffirmative ActionEmployer.

CHAIRPERSON-BIOLOGYApplications and nominations are invited for the posi-

tion of CHAIRPERSON OF THE DEPARITMNTOF BIOLOGICAL SCIENCES, The W-ichita StateUniversity. The University is located in a metropolitanarea of nearly 400,000 people and enrolls more than16,000 students. The department has eleven full-timefaculty and offers the BA, B.S., and M.S. degrees.

Candidates should have the Ph.D., experience in uni-versity teaching, a strong record of scholarly aceve-ment, and evidence of potential for academic and admin-istrative leadership. In addition to administering thedepartment, the successful candidate will be exted tocontinuc his/her research and scholarly activities andparticipatc in the teaching program. Leadership will beexpected in the recruitment of additional faculty, inpromoting faculty research, in solicitation of externalunding, and in strengthening the undergraduate andgraduate programs. Rank and salary will be ccommensu-rate with qualifications. Position begins January 1988 orearlier if possible.Send letters of interest, curriculum vitae, and names of

at least three references by 24 April 1987 to: Chairper-sOn Search Committoe, Department of BiologicalSdcences, Ihe Wichita State University, Wiita,KS 67208. An Equal OpportunitylAffirmative AcionEmployer.

CHAIRPERSON AND PROFESSOROF OBSTETRICS/GYNECOLOGY

The University of Cincinnati Collcge of Medicineinvites applications and/or nominations for the positionof Professor and Chairperson of the Department ofObstetrics and Gynecology. Candidates should havedemonstrated abilities in leadership and administrationwith a strong commitment to cinical excellence andteaching. Increased support and growth in departmentresearch is expected. The successful candidate will also beexpected to recruit new faculty and provide leadership inprogram development in the areas of endocrinology,oncology, and maternal fetal medicine.

Please send nominations and applications with curricu-lum vitae to:

Phillip 0. Bridebaugh, M.D.Chairman, Search CommitteeDepartment of AnesthesiaUniversity of CincinnatiCollee of Medicine

Cincinnati, OH 45267-0531

CHEMICAL ENGINEER. B.S. in chemical engineer-ing with a minimum of 1 year of research experience orM.S. in chemical engineering. Must have experience withFORTRAN and BASIC computer programming lan-guae and experience with commercial spreadsheet anddatbae management software for microcomputers. Willdevelop mass and energy balances for industrial andenvironmental control processes using mass transferprinciples to estimate the transport rate of pollutantsthrough solid, liquid, and gaseous phases. Wil developengineenng cost estimates for processes used to reducepollutant emissions and prepare technical reports de-scribing the work performed for the above purposes.WllR wnte computer programs to solve repetitive, appliedengineenng problems and prepare descriptive technicalreports and use spreadsheet and database managementsuch as LOTUS and DBASE III to manipulate andanalyze test data. Starting salary will be $2200 per monthfor a 40-hour work week. To apply contact: Job Service,516 North Mangum Street, Thrham, NC 28658, orour nearest Job Service office. Refer to: Job OrderNumber NC 6109273, DOT code 008.061-022. AnEqual Opporsunity/AffirmativeAction Etmlryei.

CHEMISTRY AND BIOLOGY-Position openingin mid-August 1987 in small Catholic College Seminaryin east-central Iowa. Responsible for teaching a variety ofundergraduate courses to both majors and non-majors.Qualifications: M.S. or Ph.D. in chemistry and/or biolo-gy. Salary and rank commensurate with qualificationsand experience. Application deadline: 15 April 1987.Send curriculum vitae, three references, salary history,and college placement credentials to: Chair, Depart-mcnt of Science/ath, Divine Word College, Ep-worth, IA 52045. Affimative ActionlEqual OpportunityEmployer.

CLINICAL PHARMACOLOGISTThe University of Texas Medical School at Hous-

ton invites applications for faculty positions as part of anewly created program in clinical pharmacology. Re-sponsibilities include research, teaching, and patient care.Preferred areas of interest include allergy, geriatrics, andvirology, but any clinical specialty or research area will beconsidered. Interested individuals should send a covernngletter outlining future plans, curriculum vitae indudingbibliography and the names ofthree individuals who maybe contacted as references to: Dr. G. Alan Robison,Department of Pharmacology, University of TexasMedical School, P.O. Box 20708, Houston, TX77225. The deadline for the receipt ofapplications is 30April 1987. An Equal Opporunity Employer. Women andmanortes are encouraged to apply.

CLINICAL SCIENTIST for manufacturer of diagnos-tic imagng equipment located in Cleveland, Ohio, area.Will develop and implement advanced techniques forNuclear Magnetic Resonance (NMR) imaging and re-search; work with major universities in technical clinical,and research collaboration, directing a project frominception to completion; work with engineering to in-corporate resulting techniques into machine design; par-ticipate in education and training programs for physi-cians, physicists, and magnetic resonance technicians.Requires Ph.D. in medical physics plus 2 years ofexperience working directly with NMR. Forty hours perweek; $3833 per month. Qualified applicants replyimmediately with resume to: L. llison, JO#3032780, Ohio Bureau of Employment ServicesP.O. Box 1618, Columbus, OH 43216.

The American Paralysis Association (APA) willconsider funding research by doctoral level scientistsaimed at a cure of paralysis resulting from spinal cordinjury, head injury, and stroke.APA s areas of interest are:PHARMACOLOGICAL AGENTS ANDGROWTH FACTORS

EMBRYONIC CELL IMPLANTATIONELECTRICAL, ELECTROMAGNETIC ANDLIGHT STIMULATION

SURGICAL TECHNIQUES AND PROCE-DURES

For information, write or call:Herbert E. Spiegel, Ph.D.

Research DirectorAmerican Paralysis Association55 Morris Avenue, Suitc 309

Springfield, NJ 07081Telephonc: 201-376-8884

SCIENCE, VOL. 235

POSITIONS OPEN POSITIONS OPEN

The Biological Process Sciences Departnent of Smith Kline & FrenchLaboratones, located in suburban Philadelphia, Pennsylvania, is seekingan Assistant Director of its Cell Culture Group. This individual will beresponsible for the scientific leadership of a team of experienced celbiologists who develop cell lines, expression systems, and culturetechnologies suitable for scaling-up to piot plant and manufacturingcapacities. The Group is currently engaged in highly visible assignmentsin major projects in SK&F concerned with tissue plasminogen activator,second generation thrombolytics, and growth factors with therapeuticpotential. The group is expected to conduct self-initiated research withgeneral applications as well as research which impacts specific productopportunities.Applicants should have a Ph.D. in Eukatyotic Cel Biology or BiochemicalEngineering with a solid background in eukaryotic cell biology, and aminimum of six years experience beyond the Ph.D. degree in academiaor industry. Significant experience in the scaling-up of cell cultureprocesses beyond IOL level is required. A working knowledge ofsuspension, microcarrier, and membrane culture systems, GMP, RACguidefines, and FDA guidelines for producing biopharmaceuticals in celllines is desired. The successful candidate will have a strong publicationrecord, outstanding oral and written communication skills, and highleadership potential.We offer an excellent compensation, benefits and relocation packages aswell as opportunities for personal and professional growth. Publication ofresearch resulks is encouraged and supported. For confidential review,please forward your C.V. and names of three references to: Robert F.Obst, R&D Senior Employment Consultant, SmithKline BeckmanCorporation, 1562 Spring Garden Street, Philadelphia, PA 19101. We arean Equal Opportunity Employer, M/F/H/V.

We Said ND.So You Could Say YES!

IGEN, Inc. turned down a major phar-maceutical firm's offer to purchase us becausewe believe IGEN can become one of the majordiagnostics and pharmaceuticals companies ofthe future. If you are a recent Ph.D. graduate witha research thesis in the field of chemistry and en-

zymology of oligonucleotides or an M.S. degreechemist with several years of experience innucleotide chemistry, you may be qualified forthe challenge.

RESEARCH ASSOCIATEThe successful professional will perform

chemical synthesis of oligonucleotides andmodified nucleotides and will develop purifica-tion and analytical procedures for theseproducts.

If you would like to join a dynamicbiotechnology firm dedicated to the develop-ment of proprietary diagnostic systems and phar-maceuticals, send your resume with salaryhistory to: IGEN, Inc., 1530 East Jefferson Street,Rockville, Maryland 20852.

An Emerging

AE OpportunityINC.EmploycrAn Equal Opportunity Employer

(' BIOCHEMISTSMOLECULAR /CELLULAR

BIOLOGISTSMerck Sharp & Dohme Research Laboratories iscurrently seeking individuals for doctoral, post-doctoral, and masters level positions in the Depart-ment of Biological Research. We are expanding ourresearch efforts in two areas: polypeptide growthfactors and molecular biology of ion channels.Selected candidates will contribute to research inthese areas using techniques of molecular andcellular biology and protein biochemistry.

Candidates must possess significant experience ingene cloning, or expertise in membrane biochem-istry, enzymology, and protein purification or profi-ciency in tissue culture.

Excellent salary and benefits programs accompanythese positions at our research facilities located 25miles northwest of Philadelphia.

Reply in confidence to:

Manager, Personnel Relations

MERCK SHARP & DOHMERESEARCH LABORATORIES

west Point, PA 19486EEOIAA/VH/EMPLOYER

U

Join An Emerging Leader in

DNA PRtOBETECHNOLOGY

Life Technologies, Inc. -is expanding its program todevelop new clinical diagnostic products based onnucleic acid detection.

We are seeking:ASSAY DESIGN ENGINEER

*Use your industry experience in designing andformatting of clinical diagnostics assays and systems.

* Coordinate and implement formatting concerns forDNA-based diagnostics.

* Supervise a group of interdisciplirnary scientists.We are a successful biotechnology company with a

strong reputation in the industry. The leadership enjoyedby our GIBCO and BRL products in molecular and cellbiology is evidence of our commitment to excellence.

Our salary and benefits are highly competitive. Ourlocation combines the scenic countryside of suburbanMaryland with the cultural vitality of Washington, D.C.

Other scientific positions are available.Candidates should send resumes to:

Mr. Richard L. Hotaling, Jr.LIFE TECHNOLOGIES, INC.8717 Grovemont CircleGaithersburg, MD 20877An equal opportunity employer, M/F/H/V

p- -

IN

POSITIONS OPEN

DIRECTOR, PUBLIC AFFAIRS OFFICEDirector, Public Affairs Office for the Ecological Soci-

ety of America (ESA). Scientific credentials in ecologyand experience in related environmental areas; graduatedegree preferred. Expericnce in public affairs essential,espall at the state and federal level. Familiarity withother professional societies and national scientific organi-zations. Maturity, judgment, and administrative/organi-zational skills necessary. Applicant must be able to workindependently and effectively, havc good interpersonalabilities, and possess persuasive communication skills.Salary negotiabile basecfupon experience. Job descriptionavailable upon request. Applicants should submit: statc-ment of interest in this position, resume, and three lettcrsof reference emphasizing both scientific credentials andexperience in public affairs-related activitics.

keply to: Dr. David E. Rechle, Chairman, ESAPublic Afirs Committee, Oak Ridge National Labo-ratory, P.O. Box X, Buildn 1505, MS-037, OakRidge, TN 37831-6037 by 17 April 1987.

The Ecological Soety ofAmerica is anAffirmativeAction/Equa Opporunity Employer.

U.S. DEPARTMENT OF AGRICULTUREFOREST SERVICE

SOUTHERN FOREST EXPERIMENTSTATION

ECOLOGIST, Stoneville, Mississippi. The SouthernStation is seeking an ecologist (temporary, 2 years) toconduct research on the impact of man-induced alter-ations on composition of the bottomland hardwoodforests and on their potential for producing fiber andwildlife habitat and for providing flood protection andpollution control. Research will provide increased under-standing of the ecological processes and adaptationswithin unmodified and disturbed bottomland hardwoodecosystems. Drainage, controlled and uncontrolledflooding, and partial and total timber harvest are amongcommon events in the bottomlands. The incumbentmust pull together existing data to develop ecosystemmodels that show the impacts of management practicesand provide guidelines that assure all important func-tions can be maintained without deterioration of bot-tomland ecosystems. REQUIREMENTS: In-depthknowledge of bottomland forest ecosystems; knowledge

of and skill in quantitatively evaluating relationshipswithin forest ecosystems and dynamic simulation model-

ing; and the ability to express ideas effectively orally andin writing are required. Either a master's or Ph.D. orequivalent education and experience are required. U.S.citizenship is required. Salary commensurate with experi-ence, GS-11/12 ($27,172 to $32,567). Information con-cerning the position may be obtained by telephone:504-589-3921- no collect calls. The USDA is an EqualOpportunity/Affirnative Action Employer.ENTOMOLOGIST. Two research positions availableat the assistant scientist II level begignnin 1 July 1987.The Ph.D. is required. Salary, $34, r96. (i) Entomologistto conduct field, laboratory, and greenhouse studies on

the control and biology of insects damraging vegetablecrops; (ii) medical entomologist to conduct field andlaboratory investigations on the control and biology ofticks. Please submit applications, consisting of undcr-graduate and graduate transcripts, a list of three refer-ences, curriculum vitae, reprints of publications, summa-ry of Ph.D. thesis, and a statement of research intercststo: Dr. John F. Anderson, Head, Department ofEntomology, Connecticut Agricultural ExperimentStation, P.O. Box 1106, New Haven, CT 06504. AnEqual OpportunitylAffirmativeActon Etployer.

I694.

ECOLOGIST/PHYSIOLOGIST. Conduct research intree and stand responses to nutrient limitations and waterand other environmental stresses in conjunction withprograms in forest genetics, nutrition, biotechnology,and hardwood management. Associate or experiencedassistant professor. Send resume, transcripts, and threeletters of recomention by 1 May 1987 to: A. W.Cooper, Head, Department of Forestry, North Caro-lina State University, Raleigh, NC 27695-8002.

FACULTY OPENINGSBIOTECHNOLOGY

Faculty positions are available at the full professor,associate professor, and assistant professor levels in TheCenter for Biotechnology at Baylor College ofMedi-cine. This Center is located in an new Baylor building inThe Research Forest of The Woodlands, a 25,000-acrewooded community 30 miles north of Houston. TheCentcr consists of the following divisions: (i) Hybrido-ma Technology, (ii) Recombinant DNA Technology,(iii) Protein Engineering, (iv) Bio-organic Chemistry,(v) Vision Research, and (vi) Cellular and MolecularNcurobiology. Aplicants should have research back-grounds in one of these areas. Exceptional candidatesmay also bc considered for positions as Division Heads.Although academic excellence is the determining factorin the selection process, experience and intcrcst in bio-technological applications are also desirable. Please sendr6sume, names of sevcral references, and a brief descrip-tion of research experience and future goals to:

Dr. Dominic Man-Kit Lam, DirectorIhe Center For BiotechnologyBaylor Collegc of Medicine4000 Research Forest DriveThe Woodlands, Texas 77381

An Equal OppunitylAffirmative AaonEmployer.

Oregon State University announces FOUR FAC-TLTYPOSMONS IN RESEARCH and continuing

education are being established as part of a 10-yearCoastal Oregon Productivity Enhancemcnt (COPE)Research and Development Program. Positions areavailable 1 July 1987, and will bc located in Newport,Oregon. Responsibilities are to develop and conductresearch and continuing education programs in Oregon'sCoast Range in managed second-growth forests as partof a four-person inter3isciplinary team. All positions areassistant professor, 12-month, fied-term appointmentswith annual reappointment potential for the duration ofthis 10-year program. The positions are:

(i) SIILVICULTURIST-reforestation-related silvi-culture.

(ii) SOIL SCIENTIST/HYDROLOGIST-land-slides and terrestrial-aquatic ecosystem interactions.

(iii) FISH HABITAT SCIENTIST-aquatic habitatrelationships in managed forest ecosystems.

(iv) WILDLIFE HABITAT SCIENTIST-wildlifehabitat relationships in managed forest ecosystems.

Ph.D. in specialty area or a dosely related field;experience in subject area research and Pacific Northwestconditions desirable. Salary $28,000 to $30,000 per

annum, dependent upon qualifications. Application dos-ing datc 1 June 1987. More detailed position descrip-tions are available. Send inquiries or letter of applicationresume, three letters of recommendation, and transcriptsto: COPE Search Committee, College of Forestry,Oregon State University, Corvallis, OR 97331. AnEqualEmplvpiene Opportunity/AffirmativeAction Employ-er. Cmple ith Section 501 of the Rehabiitaon Act of1973.

ICHTHYOLOGIST. The National Marine FisheriesService (NMFS) National Systematics Laboratory(located in the National Museum of Natural History)carries out systematic studies on groups of economicalyimportant marine organisms. A position for a systematicichthyologist to revise inportant groups ofmarine fishessuch as dupeids and engraulids should open about 1Scptember 1987. The current starting salary at the GS-11/12 level is $27,172 to $32,567. For further inforna-tion, contact: Dr. Michael Vecchione, NMFS System-atics Laboratory, National Museum of Natural His-tory, Washington, DC 20560. Application informationmay be obtained from: Personnel Division, EasternAdministrative Support Center, 253 Monticello Ave-nue, Room 409, Norfolkz,VA 23510; telphone: 804-441-6880. An Equal Opportunity Emloyf r.

Princeton University-The De¶artnent of Biologyhas an opening for 1 year at the evel of LECTURERbeginning in September 1987. The successful applicantwill teach a fall laboratory course in experimenta

Iverte-brate biology, which is complementary to an existinglecture course, emphasizing neuroendocrine mechanismsof vertebrate reproductive biology. During the springsemester, the lecturer will teach halfof a lecture course in

animal behavior emphasizing mechanism of behavior.Opportunity will bc available to carry out some researchin the area of animal behavior including vertebratereproductive biology. Ph.D. degrec or equivalent re-quired. Submit letter of application, curriculum vitae,and have three letters of recommendation sent to: Mrs.E. Lechner, Secretary to the Search Committee, De-partment of Biology, Princeton University, Prinec-ton NJ 08544.

Deadline for receipt of application material is 13 April1987.Princeton Universty is an Equal OpponitylAffirmative

Acin Employer.

MICROBIOLOGIST: The Department of Micro-biology, University of Alberta, invites applications foran independent research position from qualified individ-uals with demonstrated research abilities in basic orapplied problems in microbiology. Candidates usingbiochemical/molecular approaches will be accorded spe-cial preference. Candidates should have a recent Ph.D.and relevant postdoctoral experience. The position is a 5-year renewable term appointment at the assistant profes-sor level (salary range: 331,612 to $45,340) and will becontingent upon a successful application for a competi-tive award from an external agency. Successful applicantspursuing research of medical relevance may also beeligible for substantial research establishment funding.Duties include development of an independent research

program, graduate student supervision, and some appro-priate classroom teaching. Applications, containing cur-riculum vitae, names, addresses, and tcelphone numbersof three or more referees, and a concise but specificdescription of research interests, and proposed workshould be sent to: Dr. S. E. Jensen, Department ofMicrobiology, University of Alberta, Edmonton, Al-berta, Canada, T6G 2E9. The closing date for applica-tions is 30 June 1987.

The Univerity ofAlberta is an Equal Opportunity Em-ployer, but pnorty will be given to Canadian citzns andpermanent residents ofCanada.

MOLECULAR BIOLOGY AND BIOCHEMIS-TRY: Graduate assistantships in a department emphasiz-ing student-faculty interactions. Research in regulationo gene expression, structure and function of heterochro-matin, protein-nucleic acid interactions, DNA replica-tion, oncogenes, biochemistry of embryonic develop-ment, physical biochemistry, NMR spectroscopy, ascor-bic acid, phosphate structure and mechanisms, and pro-tein folding. Tuition remission, dependency allowance,oood fringe benefits and opportities to teach. Only atewremaming openings. Write Graduate Admissions,Department ofMolecular Biology and Biochemistry,Wesleya University, Middletown, CT 06457 or tele-phonc203-347-9411 cxtension 2796 days or 203-34-90evenings.

NEUROLOGIST-Board Certified. Instructor level.Full-time, nontenure position with training and experi-ence in immunobiology of sleep disorders. Contact: N.A. Vick, M.D., Evanston Hospital, 2650 Ridge Ave-nue, Evanston, IL 60201. An Equal Opportunity Em-ployerMIF.

NEUROPATHOLOGISTThe Department ofPatholo at Cohunbia Univer-

sity, College of Physicians and Sugons, seeks one ormore senior neuropathologists to assume diagnostic,teaching, and research functions at the college and itsaffiliate hospitals.The individuals chosen must have formal training in

biochemistry, Board Certification in pathology and neu-ropathology, and substantial current research support.The appointment is envisioned at the associate profes-

sor leve and the applicant must meet the Columbia

standards for appointment to tenured status. Resume to:Department ofPathology, College of Physicians andSurgeons, 630 West 168 Street, New York, NY10032. AffirmativeActionlEqual Opportunity Employer.

SCIENCE, VOL. 235

DEVELOPMENTAL BIOLOGYThe Salk Institute

The Salk Institute invites applications for Assist-ant Professor positions in developmental biolo-gy, particularly in areas related to neurobiologyand cancer research. Candidates should havePh.D. or M.D. degree and postdoctoral researchexperience. Please send resume, outline of re-search interests, and names of three referencesto:

Faculty ChairThe Salk InstituteP.O. Box 85800

San Diego, CA 92138An Equal Opporunity Employer.

POSITIONS OPEN POSITIONS OPEN

MOLECULAR GENETICSBIOCHEMISTRY

The Henkel Group, a leader in applied oleochemistry, seeks Scientiststo join their expancing biotechnology efforts. Posiqlqs of responsibilityare available at Henkel's U.S. R rch Facility in Santa Rosa,Califomia.

RESEARCH ASSOCIATFThe successful candidate will report to the Director and assist in pro-gram development as well as conduct research. Applicants shouldhave a Ph.D. in Biochemistry, Microbiology or related field and five ormore years experience after postdoctorate in industry or academia. Sci-entific leadership in eukaryotic molecular genetics (yeast, fungi, plants)is essential. Experience in directing Ph.D. scientists is required.

SENIOR RESEARCH SCIENTISTSApplicants should have a Ph.D. in Biochemistry, Microbiology or relatedfield, preferably with postdoctoral experience. Successful candidateswill plan, direct and conduct research in the use of enzymes for newand improved biochemical conversions.For confidential consideration, send your resume, list of references andsalary requirements by April 17, 1987 to:

Ms. Carol SullivanDirctor of Personnel

Honkel Research Corporation2330 Clrcodian Way

Santa Aos, CA 95407An Equal Opportunity Employer M/F

Research Scientist(Neurochemist)

G.D. Searle is a worldwide leader in the pharmaceutical industry. Majornew directions have recently been identified by the Department ofCentral Nervous System Diseases lResearch. An opportunity now

exists for a qualified Research Scientist to join an active research programin the discovery of novel drugs for the treatment of CNS disorders.Responsibilities include:

* Establishing and supervising a biochemical laboratory* Investigating and definino the mechanism of action of novelcompounds using biochemical and pharmacological methodologies

* Collaborating with other investigtors in multidisciplinaryresearch programs

* Participating as an integral member of project teams to determineresearch direction

The qualified candidate will have experience in radioreceptor binding and isolatedtissue assays as means to pharmacologically characterize drugs. Experience inthe measUrement of neurotransmitters and intracellular messengers using HPLC

and radioimmunoassay methods is desired. Required: Ph.D. in BiochemistryPharmacology or Physiology, with minimum 2 years postdoctoral experience.Must have record of publication demonstrating ability to undertake independentand creative research in the neurosciences.This position offers excellent salary and benefits package and is located in anorthern suburb adjacent to Chicago. Our location offers access to a variety ofcultural and recreational facilities, several fine universities and an active neuro-science community. Qualified candidates may respond in strict confidence to:G.D. Searle & Co., R & D, Professional Staffing, A-i, 4QA, 4901 Searle Parkway,Skokie, Illinois 60077. An Equal Opportuni;%mployer.

;EARLE

Applications Are invited for the positionof a

H PLUI O6YCandidates should have a strong re-search background in Plant Sciences atthe cell and/or molecular level, as well asa demonstrated ability to develop an in-dependent research programme a,nd tolead a group. The candidate will be ex-pecteo to carry out research in an areacomplementing the work of five othergroup leaders: Witek Filipowicz (geneexpression and RNA processing), Barba-ra Hohn (genetic flux in plants), ThormasHohn (molecular plant virology), PatrickKing (a genetic approach to plant hor-mones), and Fraderick Meins (plqnt de-velopment). The groups each csist ofpostdoctoral fellows, graduate students

and technical staff, and occupy indepon-dent laboratories.iWe would prefer to make the appoint-ment at the level of a senior group leader,but an appointment at a more junior lovelis not excluded. A curriculum vitae and alist of publications should be' subrpittedbefore April 30, 1987 to: Serch Co4m-mltee (Plant Group Leader), Fredr1thMiescher-instltut, P.O. Box R543,4002Basel, Switzerland.

Enzyma tics, Inc.

Enzymatics is a well.finanoed company develowg a new genQration of cobrimetric diagnosticsfor medical and industrial markets. Highlymotivated scientists are being sought for thefollowing positions:

Resaarch Scientist- Requires a PhD inChemistry or Biochemistry and 2 + yearq postdoctoral experience. A "knack" for syntheticorganic chemistry and enzymology is required.Process Develo et Engineer- This "hands-on" position is rsponsible for establishing andmaintaining our manufacturing processes Re-quires 7+ years of phmaceutical ordiagnosticexperience KnowldgI of plastics or thin filmtechnology is helpful.

mmseech AssImW- Requies an MSIBS with atleast two years of laboratory experience inorganic chemistry or Oiochemistry.

These positions respent a golden opportunityto get in on the ground faorf arapidly growing,dynamic company. Enzymatics offers competi-tive salaries and a stoc* participation plan for allemployees. We will son be relocating tothe Philadelphia area. Pease submit cover letter.resume and referpnces to: Personnel,ENIYMATIT INC, Sidg I, Behbleem Tech--alagyCepel uS n Drv Bethle PAIIt& An Equal Opportunity Employer

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SENIORRRESEARCHThe LILLY RESEARCH LABORATORIES, a Division ofEli Lilly and Company is seeking an established SeniorVirologist to lead our antiviral research programThe applicant should be an accomplished doctoral level

virologist with a drug discovery orientation and prven trackrecord The position requires a scientist familiar with currenttissue culture techniques and animal models, with abackground vvel founded in molecular virology PreferencewAll be given to candidates having knowledge of clinicalvirologyThe Senior Virologist will be responsible for developing

and implementing an innovative antviral progran Broadlybased scientific experience and good communicationskills will be essential for leading our multi-disciplinarydrug discovery group

Qualified candidates should send teir curriculumvitae to:John W. Crookc

- C, owbge RPaUonsEiLily adComipanyUllCoporteCenter

ndianapos Ind 46285Equal Opportuny Employe

CHIEF, RETROVIRUS DISEASES BRANCH, Divisionof Viral Diseases, Center for Infectious Diseases,Centers for Disease Control (CDC). Applicationsand nominations are invited for a scientist to serveas leader of a newly formed laboratory and epidemi-ology research unit in the Division of Viral Diseases.The Branch Chief directs and participates in a basicresearch program to develop better understandingof the human retroviruses, the diseases they cause,and the means for their control. M.D. degreerequired for Medical Officer or an earned doctoraldegree is preferred (Ph.D. or equivalent), distin-guished achievement in basic or applied research inretrovirology or retrovirus diseases, and demon-strated capacity for administrative leadership. Formedically qualified persons, the salary range is$52,347-$70.800 and for non-medically qualified,$45,763-$69,976. The Branch has been newlyformed and the new director is exp,cted to build astrong research program which shall include non-AIDS as well as AIDS retrovirus related research.Diverse areas of research are encouraged as arecollaborations with scientists in the other virologicaldisciplines in the Division and Center.

Interested candidates should send a current curricu-lum vitae, and names of three professional refer-ences to:

Sharlyn L. WilkinsonPersonnel Management OficeCenters for Disease Control1600 Clifton Road, N.E., 1-1058Atlanta, Georgia 30333

Further information about the position can be ob-tained from:

CarIes Lopez, Ph.D.Chairman, Search CommitteeDivision of Viral DiseasesCenters for Disease Control1600 Clifton Road, N.E., 7-206Atlanta, Georgia 30333

CDC is an Equal Opportunity Employer and providesa Smoke-Free Work Environment.

Senior MicrobiologIst(Infectous DiseaseR)

The LILLY RESEARCH LABORATORIES, a division of Eli Lillyand Company is seeking candidates for the position ofSenior Microbiologist in the Department of InfectiousDisease Research.

Applicants must have a doctoral degree. PRstdoctoralexperience is highly desirable. The applicant should haveexpertise in infectious disease research including anextensive understanding of the interaction betweenantimicrobial agents and pathogenic microorganisms. TheSenior Microbiologist filling this position will establish alaboratory dedicated to the discovery and evaluation ofnovel modes of antimicrobial chemotherapy Interdisciplinarycooperation with other investigators, such as medicinalchemists, enzymologists, physiologists, toxicologists,biochemists, immunologists, and physicians will be essential

Qualified candidates should send their curriculum vitae to:John W. Crooks

Goileg fons. - - ~(SM 11DR)

IElI Lilly and CompanyLilly Corporate CenterIndlanapo Is, Indiana 46285Equal Opportunity Emplwr

Applications are invited for a positionof

PROFESSOR OFBIOTECHNOLOGY

at the Insfitute for Biotechnology at theETH Zurich.

Duties of the new professor will in-clude teaching at undergraduate andgraduate levels. In addition to the ex-isting curriculum new courses may beintroduced. In research cooperationwith one or more of the existing groupsworking in gene technology, cell biolo-gy, process engineering and plant mo-lecular biology is expected.

The successful candidate will haveteaching experience and an outstand-ing research record in the area of geneexpression using animal cell systems;experience with transgenic animals isdesirable.

Applicatiors with curniculum vitae andlist of publications (no publications)should be directed before April 30,1987, to the Prsident of the ETHZurich, ETHZentrum, 8092 Zurich,Switerland.

i

Senior ResearchImmunologist

To join a multidisciplinary team of biochemists, cellbiologists, and pharmacologists seeking new therapeuticapproaches for the control of autoimmunity and inflamma-tion. The successful applicant will have primary respon-sibility for the design and development of novel animalmodels of inflammatory and immunologic disease pro-cesses. A Ph.D. in immunology or pharmacology and 2-3years of postdoctoral experience is required. A strongbackground in biochemistry and in vivo models of inflam-mation is highly desirable.

Staff ImmunologistTo participate in a program on the development oftherapeutic human monoclonal antibodies. A strongacademic background (B.S. or M.S. degree) in such areas asbiochemistry, cell biology, and immunology with ex-perience in tissue culture, protein purification, and im-munochemistry is preferred.Merck Sharp & Dohme Research Laboratories are locatedin Rahway, New Jersey approximately 20 miles south ofNew York City. Our salaries, benefits, and growth potentialare excellent. Interested candidates should specify whichposition they are applying for and submit their curriculumvitae and salary requirements to: Ms. Alalna L. Love, Merck& Co., Inc., PO. Box 2000, RSOM-TLI, Rahway, New Jersey07065. Equal Opportunity Employer.

CK

The Universities Space Research Association andThe University of Maryland seek a

DIRECTORfor a

CENTER OF EXCELLENCE INSPACE DATA AND INFORMATION SCIENCES

at theNASA/Goddard Space Flight Center

Applications are invited for a Director to head a new

research consortium of university, industry, and governmentcomputer scientists being established as a Center ofExcellence in Space Data and Information Sciences atNASA's Goddard Space Flight Center in Greenbelt,Maryland. The Center of Excellence will be operated by theUniversities Space Research Association, and the Directorwill hold a fully tenured faculty position in the ComputerScience Department of the University of Maryland, CollegePark. The Center of Excellence will involve term-memberresearchers from leading university and industry computerscience departments across the country through the use ofhigh-bandwidth nctworks, in addition to supporting a

resident and visiting research staff. The charter of theCenter of Excellence will be to carry out state-of-the-artresearch on space data and information sciences in areas ofpotential long-term application to NASA programs in thespace station era. Among the proposed thrusts for theCenter of Excellence are the study of massive data basesystems and architectures, image data compression, highspeed on-line distributed data access systems, parallelprocessing applications, dynamic pattern recognition, expertdata systems and natural querying languages, andautomation and tele-robotics. The staff, including theuniversity and industry members, will have access to NASAsupercomputers, networks, parallel processors, dataarchives, image analysis systems, robots, etc.

Qualifications: The Center of Excellence will be the firstresearch institution in the computer and informationsciences to make extensive use of high band-widthcommunication technology to link together its memberfaculty. We seek a dynamic and visionary scientist to leadthis unique "telecenter". Applicants must be qualified for a

tenured position in the Computer Science Department ofthe University of Maryland; must be knowledgeable inadvanced data management and computational methods;and must have a demonstrated ability to lead collaborativeresearch projects involving industry, university, andgovernment. Salary and benefits are competitive andattractive and will depend on the individual's qualifications.

Apply no later than 15 May 1987 with complete resume on

academic, professional, and personal data, including threereferences, to Dr. Robert Dorfman, Acting Dean, Collegeof Computer, Mathematical and Physical Sciences, Room2300, Mathematics Building, University of Maryland,College Park, Maryland, 20742, (301) 454-4906.

The University ofMaryland and theUniversities Space Research Association are

Equal OpporunityAffirmativeAction Enmployers

AssociateScientistBioanalytica Development Laboratory

Schering-Plough, a $2.4-billion corporation, has estab-lished a worldwide reputation for leadership in the research,manufacture and marketing of pharmaceutical and per-sonal care products.We offer you an opportunity to join our Bioanalytical Lab-oratory research team to participate in the development ofprotein separation projects, including improving gel proce-dures. You will also provide technical support to depart-ment scientists and engineers.This is a hands-on position, requiring in-depth knowledge ofelectrophoresis; iso-electric focusing; and protein blottingtechniques.Credentials must include an MS or BS in Biology, Biochem-istry, or equivalent, plus 1-6 years' (depending on degree)laboratory experience in gel electrophoresis.We offer an attractive salary and benefits package and astimulating, highly supportive research environment. Toexplore this opportunity, forward your resume and salaryhistory, in confidence, to: Ms. I. Connelly, Schering-PloughCorporation, 101 1 Morris Avenue, Union, NJ 07083. We arean equal opportunity employer.

9i3 Schering-Plough

POSITIONS OPEN

MYCOLOGISTIMOLECULAR SYSTEMATICSCareer position as a mycologist/molecular systematistwith the Northern Regional Rescarch Ccnter, Agri-cultural Research Serice (ARS), U.S. Department ofAgriculture (USDA). Research concerns the systemat-ics and genetic relationships of agriculturally inportantaspergill'i and penicillia determined from comparisons ofnucleic acids. The successful applicant will join a tearn ofscientists in the ARS Culture Collection working onmolecular systematics of various taxa. Graduate trainngand postdoctoral or equivalent experience in mycologyand biochemistry/molecular biology are desirable. Somebackground in genetics is considered helpful. The Centerprovides relocation expense assistance. U.S. citizenship isrequired. Salary is commensurate with experience (GS11-12, $27,172 to $42,341 per annum). For informa-tion on the research program, tclephone: Dr. C. P.Kurtzman, 309-6854011, extension 561. For appli-cation procedures and forms, telephone: Mrs. HelenSweeney, 309-685-4011, extension 632. Applicationsin response to this advertisement should be marked7N006 and must be received by 15 June 1987. Mail to:Helen Sweeney, Northern Regional Rescarch Center,ARS, U.S. Department of Agriculture, 1815 NorthUniversity Street, Peoria, IL 61604. The USDA is anEqual Opportunity/Affinnativc Action EVployer.

IN VITRO FERTILIZATION. Position for Ph.D. orM.S. in reproductive physiology, endocrinology, gametebiology to join AFS accredited, IVF Program. Responsi-bilities include clinical laboratory service and basic re-search with the potential for extramural funding. Sendapplication, curriculum vitae, and references to: W. PaulDmowski, M.D., Ph.D., Section ofRE/I, DepartentofObstetrics and Gynecology, Rush Medical College,600 South Paulina, Chicago, IL 60612. Equal Oppor-tunity Emplayer.

PHARMACOLOGY FACULTY POSMONThe Department of Pharmacology and the Cancer

Center ofthe Universit of Rochester invite applica-tions for a tenure-track facultyposition, which ma befilled at the rank of ASSISTANT OR ASSOCIATEPROFESSOR. The successful applicant may hold aprimary appointment in the Department of Pharmacolo-

or joint primary appointments in the Department ofFharmacology and in the Cancer Center. Applicantsshould have a Ph.D. degree in pharmacology, biochemis-try, physiology, or chemistry, or a related field, an M.D.degree, or both, postdoctoral research training, the po-tential to attract research support for an independentresearch program, and an interest in professional andgraduate education. Applications are specifically soughtfrom individuals with expertise in drug and chemicalbiotransformation and bioactivation, induding chemicalcarcinogenesis, and who apply modern techniques ofnuclear magnetic resonance spectrometry, mass spec-trometry, cell and molecular biology, or physiology totheir investigations. The deadline for applications is 8May 1987. Applicants should forward curriculum vitae, alist of publications, three letters of recommendation orthe names of three referees, and a summary of currentand future research interests to: Search Committee,Department of Pharmacology, Box Pharmacology,School of Medicine and Dentistry, 601 ElmwoodAvenue, Rochester, NY 14642. The Univesity ofRoch-ester is an Equal Opportunity Employer, and applicatonsfrom women andfiom minoritygroups are encouragd.

POSTDOCTORAL POSITIONS IN BIOCHEMI-CAL TOXICOLOGY. Two positions are availableimmediately for Ph.D's with a strong background inbiochemistry, organic or medicinal chemistry, drug me-tabolism, or pharmacology. Research projects underinvestigation deal with the biotransformation and bioac-tivation of xenobiotics with a special emphasis on thebiosynthesis, physiological disposition, bioactivation,and cellular toxicity of amino acid S-conjugates. Candi-dates should send curriculum vitae, a brief statement ofresearch experience, and the names ofthree references to:Dr. M. Wt. Anders, Department of Pharmacology,University of Rochester, 601 Elmwood Avenue,Rochester, NY 14642. Equal Opportunity EmployerMIF.

PLANT BIOLOGIST: The College of Arts andSciences ofWidener University invites applications fora tenure-track position as Assistant Professor ofBiolo-

beginning 1 September 1987. Ph.D. (botany orgy) required. Undergraduate education is the

primary emphasis of the position. Application reviewbegins 1 April 1987. Letter of application, completecurriculum vitae, and three letters ofreference should besent to: Robert Morris, Biology Department, Widen-er University, Chester, PA 19013.

POSTDOCTORAL ASSISTANT/INSTRUC-TOR POSMIION available immediately in project us-ing recombinant DNA and monoclonal methods toexamine neural cell surface antigens [see Cole ct al., J.CelUBiol. 103, 1739-1744, (1986) and Williams etal.,J.CeU Biot. 101, 36-42, (1985). Experiments will utilizecell culture models to cxamine expression, regulation,and biologic function of both normal and in vitromutagenized cDNAs. Experience in molecular biology,immunology, and/or cell culture preferred. Salary depen-dent on quilifications: minimum $19,000. Appointmentto faculty title series as Instructor possibkc for qualifiedapplicants. Pleasc send curriculum vitae, statement ofinterests, and names of three refercnces to: Dr. RichardAkeson, Division of Basic Research, Room 629 IDR,Childrens Hospital Research Foundation, Cincinnati,OH 45229.

POSTDOCTORAL FELLOW to work with steroidreceptors/receptor interactions with chromatin/steroidgenc (oncogene) regulation. Rcsearch involves proteinpurification, antibody detection of receptors and chro-matin protein, and some molecular biology (cloning andgene transcription analyses). Will train individuals notexperienced in specific areas. Contact: Thomas C. Spels-berg, Ph.D., Department of Biochenistry and Molec-ular Biology, Mayo Clinic, Rochester,MN 55905.AnEqual Opportunity/Affimate Action Institution.

POSTDOCTORAL FELLOWMOLECULAR NEUROBIOLOGY

Howard Hughes Medical Institute, MassachusettsGeneral Hospital: Applications are invited from scien-tists, preferabl with experience in molecular biology, towork on projects relating to the molecular biology ofdeveloping mammalian neurons. Specific projects con-cern idcntification of proteins related to growth conefunction, investigation oftheir gene structure and regula-tion, and identcation of their cellular mechanisms ofaction. Applications with curriculum vitae should be sentto: Dr. M. Fishman, Howard Hughes Medical Insti-tute, Jackson 902, Massachusetts Gcneral Hospital,Boston, MA 02114.

POSTDOCTORAL POSITIONAvailable after July 1987 for neurobiologists, biochem-ists, and molecular biologists interested in multidis-ciplinary investigations of the basic mechanisms underly-ing diseases of the nervous system. Applicants shouldsend resume and letters of recommendation to: DonaldL. Price, M.D., Neuropathology Laboratory, IheJohns Hopkins University School of Medicine, 509Pathology Building, 600 North Wolfe Street, Balti-more,MD 21205-2182. Affirmative Acion/Equal Op-porunity Employer.

POSTDOCTORAL POSITION: Mechanism and en-

hancement of transdermal drug delivery. The objectivesofthis NIH-supported project (starting spring 1987) are(i) to characterize, using calorimetric and spectroscopictechniques, the biophysical and structural origins of theskin's permeability barrier, and (ii) to apoply this informa-tion to the optimization of steroidal drug deliverv. Theprogram involves collaboration between the Universityof California, San Francisco (UCSF) and Pfizer CentralResearch. The appointee will conduct research, there-fore, in both San Francisco and Groton, Connecticut.Applicants with strong backgrounds in biophysical,pharmaceutical, and/or biological chemistry are encour-aged to apply by sending curriculum vitae and thenames of two references to BOTH: Dr. Richard Guy,Departments of Pharnacy and PharmaccuticalChemistry, UCSF, San Francisco, CA 94143, and Dr.Russell Potts, Pfzer Centrl Research, Groton, CT06340. USCF is an Equal OpportunitylAffirmativeActionEmployer.

I698

POSTDOCTORAL POSITION: Seeking Ph.D.trained in sensory neurophysiology to participate instudies examining the contribution of sensory-limbicinteractions to learning and mcmory. Expericnce inextracellular single-unit recording techniques and work-ing knowledge of computer programmng necessary.Send curricu[um vitae, copies of relevant publications,and the names, addresses, and telephone numbers ofthree references to: Dr. J. E. LeDoux, Division ofNeurobiokigy, Cornml University Medical College(CUMC), 411 East 69 Street, New York, NY 10025CUMC is an Equal Opportunity Employer.

POSTDOCTORAL POSMON-MassachusettsGeneral Hospital and Harvard Medical School, Bos-ton. Postdoctoral position in immunology/biochemistryavailable on or after 1 July 1987 for quafied candidateswith Ph.D. or M.D. degree; minimum term 2 years.Research involves structural and functional characteriza-tion of mutant antibody combining sites at protein andDNA level. Training includes immunochemistry, somat-ic cell fusion, protein and nucleotide sequence analysis,molecular biology in collaboration with interdisciplinaryresearch group. Candidates should send their curriculumvitae, statement of research interests, and names of threereferences to: Dr. Michael N. Margolies, Massachu-setts Gcneral Hospital, 15 Parkinan Street, Boston,MA 02114. Tdelphonc: 617-726-8552.

POSTDOCTORAL POSMIION for experimental ani-mal psychologist. To investigate drug interactions asevidenced by physiological condition responses (par-ticularly heart rate) as well as efects on condtioned tasteaversions (particularly their attenuation). Starting dateflexible but prnor to August 1987. Scnd applications to:Professor Sam Revusky, De ment of1sycholoMemorial University of N f dd, St. John'sNewfoundland, Canada, AIB 3X9. Telephonc 709-737-7584.

POSTDOCTORAL POSITION for 1 year availableimmediately to join a research team working on molecu-lar approaches to study viral diseases. Exerience inbiochemistry, molecular biology, or cell biology re-quired. Salary commensurate with qualifications andexperience. Excellent fringe benefits. Send curriculumvitae, a brief summary of research interests, and threeletters of reference to: Dr. Beatriz G. T. Pogo, Centerfor Expimental Cell Biology, Mount Sinai School ofMedicne, One Gustave L. Levy Place, New York, NY10029. An Equal Opportunity/AffirmativeAction Employe.

POSTDOCTORAL POSMIION is available from July1987 for 3 years to study the neurobiology of specificglycolipid antigens involved in cell-cell interaction in theembryonic developing nervous system. A background incomplex carbohydrate biochemistry, neurochemistry,and cell biology is preferred. Send curriculum vitae withnames of three references to: Dr. Firoze B. Jungalwala,Department of Biochemistry, E. Kennedy ShriverCenter for Mental Retardation, 200 Trapelo Road,Waltham, MA 02254.

TWO POSTDOCTORAL POSTIIONS are availablefor work on ascts of ciguatera research. One positioninvolves the development and improvement of tech-niques and procedures for growth, harvesting and extrac-tion of toxic dinoflagellates and the rapid separation andpurification of toxins using this layer, column, and highpressure liquid chromatography. Experience with cultureof dinoflagellates is essential. The second position in-volves the electrophysiological investigation ofthe effectsof marine toxins on isolated preparations, experimenta-tion to develop new bioassay methods or systems foridentification and quantitation of toxins and elucidationof the mechanism of action of the toxins. Experiencewith voltage clamp is essential and experience with NMRor HPLC is desirable. Twelve-month appointrnents areavailable with possibility ofrenewal. Applications includ-ing curnculum vitae and three reference letters should besent to:

Dr. Donald M. MillerDepartment of Physiology

Southern Illinois University at Carbondale (SIUC)Carbondale, IL 62901

This project is funded by the federal government.SIUC is an Equal Opportunity Employer.

SCIENCE, VOL. 235

POSITIONS OPEN POSITIONS OPEN

Ph.D RESEARCH SCIENTISTSThrough over 60 consecutiveyears of growth, Ayerst Laborator-ies, subsidiary of Fortune 100American Home Products Cor-poration, has maintained its com-mitment to research.Today, more than ever, we viewresearch as the key to the future,the cornerstone for enhancing ourstrong position. To accomodateexpanded research activity, weare seeking Ph.D. Research Sci-entists for positions in "neuro-pharmacology" and "drug me-tabolism".

NEUROSCIENTISTS/CNSPHARMACOLOGIST

The successful candidate shouldpossess a doctorate degree inneurobiology/pharmacology, withpostdoctoral research experienceand demonstrated strength inbehavioral pharmacology and/orneurochemistry. This senior posi-tion is focused towards studying

the effects of anti-senility drugs onlearning/memory performance inanimals. A broad knowledge ofCNS pharmacology is required.Strong communication and com-puter skills are necessary, as isthe desire to be part of a multi-disciplinary team drug discov-ery/research effort. RESPONDTO DEPT KK.

DRUG METABOLISMThe successful candidate shouldhave a Ph.D. in chemistry, phar-macology, pharmacy or biochem-istry with approximately 2 yearspost-doctoral experience in drugmetabolism and/or pharmacoki-netics, the use of radioactivexenobiotics (carbon-14 and/ortritium), chromatographic techni-ques, and the analysis of drugsand their metabolites in biologicalfluids. Experience with laboratoryanimals and/or training in thepurification and structure elucida-

tion of xenobiotic metaboliteswould be additional assets. RES-POND TO DEPT MC.Ayerst offers an excellent salaryand benefits package togetherwith outstanding opportunities forcareer advancement. Our ultra-modern laboratory facilities areconveniently located in a pictures-que central New Jersey setting.Interested candidates should for-ward their curriculum vitae in-dicating their salary history andposition of interest to:

PERSONNEL MANAGER

AYERSTA,si ~LABORATORIESLv iRESEARCH, INC.CN800

Princeton, New Jersey 08543-9990Equal Opportunity Employer M/F/H

MENARINI, a leader in pharmaceutical research, isseeking an experienced, highly qualified SCIENTIST tofill a challenging top management position in its re-

search department.

The successful candidate will be responsible for coordi-nation of research programs at Menarini as well as itsrelated companies and the development of relativeresearch centers.

He will be assisted, whenever necessary, by internation-ally recognized experts, and free to select his collabora-tors. Adequate means will be provided to carry outresearch programs.

The research centers are located in Florence and Pome-zia (Rome). Headquarters are located in Florence.

An attractive salary is offered commensurate to qualifi-cation and experience.

Menarini will also consider the hiring of qualified youngscientists with experience in cardiovascular, CNS, endo-crine, respiratory or genito-urinary areas.

Qualified candidates are requested to submit theircurriculum vitae and a list of recent publications to:

A. Menarini s.a.s.-Pharmaceutical Industries-Via Sette Santi, 350131 Florence, Italy.

Molecular GeneticistThe Molecular Genetics Department of Pfizer CentralResearch has an immediate opening for a laboratoryassistant. Applicants should possess a BS or MS inMolecular Genetics or related field and have experiencein recombinant DNA methodology, preferably in yeast orE. coli.You will bepartofa small multidisciplinaryteam, carryingoutexploratoryprojects. Dutieswill includegenecloning,expressing mammalian genes in yeast and radioisotopelabelling of DNA.In addition to a stimulating scientific environment, wealso offer competitive compensation, benefit packageand the opportunity to live in an attractive Connecticutshore community. Please send resume and descriptionof research experience to: Lorraine C. Corr, PersonnelAssociate, Pfizer Central Research, Eastern Point Road,Groton, CT 06340.

An equal opportunity employer

mIm

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Research

...to build a better tomorrow

GENETICS INSTITUTE, INC., located in Cambridge, MA, is a recog-nized leader in the field of biotechnology. Our research is committedto the development and application of recombinant DNA technologyto human health care, agriculture, and chemicals. Recent expansionof our research and development efforts has created newopportunities:

CELL BIOCHEMISTRYWe currently have an opening for a staff scientist to design and con-duct research in the area of cell biochemistry. The ideal candidatewill have a Ph.D. in Biochemistry or related field with a minimum ofthree years' post doc experience in cellular biochemistry with par-ticular emphasis on the biochemical characterization of proteins andtheir interaction with cellular targets. As a member of amultidisciplinary team, the candidate will be expected to participatein the identification and research planning of new project areas. Re-quisition # 256.

rONA TECHNOWBGYDEVELOPMENT

An opening exists for a staff scientist to develop state-of-the-arttechnology in the area of rDNA research. The ideal candidate willhave a Ph.D. in molecular biology with five years of relevant ex-perience clearly demonstrating the ability to develop novel rDNAtechnology. Requlsitlon # 269.

PROTEIN CHEMISTRYWe have several openings for BS/MS level Research Associates whowill join our structural Protein Chemistry Group which focuses on thebiochemical characterization of recombinant DNA-derived proteins.Candidates should have a general background in either enzymologyor protein biochemistry and a working knowledge of techniques utiliz-ed to examine protein structure such as SDS-PAGE, IEF, enzymeassays or HPLC of peptides and proteins. Individuals possessingspecialized skills in areas such as amino acid analysis, HPLC pep-tide mapping or gas phase sequencing of proteins would be par-ticularly well suited. Requisltlon #482.

PROEIN PHARMACEUTICSCHEMISTRY

We have an immediate opening for a research staff member to workin a rapidly growing group responsible for the formulation andstabilization of protein pharmaceuticals produced via recombinantDNA technology. A Bachelor's degree in biochemistry or relateddiscipline is required, with subsequent work experience (0-5 years)preferably being in the area of physiochemical characterization ofproteins and/or their purification. Knowledge of the theory and prac-tice of a variety of methods used to examine the physical structureof proteins, such as HPLC, SDS-PAGE, fluorescence and CD spec-troscopy, would be helpful. Requistion #499.We oftr a stimulating scientific environment In addition to acompetitive salary, equity participation and comprehensivebenefits packag. Qualified candidats should forward theirresume, In confdtence, to Cindy Molnar, Employment Reptative. Please refer to the appreprite Requisition # when app!yIng for any of the above positions.See our postng at the March FASEB meeting In Washington, D.C.

Genetics Institute87 Cambrdgerk Drlv Cambg MA 02140

An Equal Opportunity/Affirmatv Action Employer

IrNEs H&CMOLPHe[E (COHED.kfy nHKQEXCITING OPPORTUNITIES FOR

QUALIFIED INDIVIDUALS

The CompanyThe Macrophage Company, Inc. isdevelopingcytotoxic factors frommacrophagesand human monocytes for treatmnent ofcancer and otherinfectious and rheumatic diseases.The Company will support a team of scientists at the Univ. of TexasSystem Cancer Center/ M.D. Anderson Hospital and Tumor Institutewho will use recombinant DNA and standard protein purificationtechniques to characterize and purify these factors.Postdoctoral Positions AvailableThe newly formed scientific team is seeking a protein chemist ex-

perienced in small and large scale modem bioseparation techniques(e.g., HPLC and immunoaffinity chromotography).There is also a position for a molecular biologist who has experiencein eukaryotic gene cloning techniques (e.g., cDNA library construc-tion, substraction hybridization, and sequencing).

Compensation for both positions will be commensurate withexperience.Your CommitmentQualified persons with a background or interest in immunology or

willing to make a twoyearcommitment to this exciting project shouldsubmit CV and references to:

Martin P. Sutter, PresidentThe Macrophage Company, Inc.2170 Buckthorne Place, Suite 350-AThe Woodlands, TX 77380(713) 363-7145

MEDICAL UNIVERSITY OF SOUTH CAROLINAPOSTDOCTORAL FELLOWSHIPS IN

CELL AND MOLECULAR PHARMACOLOGYFellowships are available for Ph.D., Ph.D./M.D. or M.D. candidates

in an interdisciplinary environment of basic and clinical scientists study-ing the tissue specific expression and function of gene-protein systemspertinent to the design and actions of new cardiovascular and otherdrugs. Areas of particular interest include: calcium transport proteins inexcitable tissues (G.E. Lindenmayer); cellular roles of kalllkreins andkinins (H.S. Margolius, J. Chao, D. Miller); atriopeptins (M.G. Currie);thromboxane and other eicosanoid receptors (P.V. Halushka, D. Mais);hormones and cell structure (D.A. Baron); adenosine receptors incardiac myocytes (W.H. Newman, J.G. Webb); neural and vascularamine transport and related proteins (T.E. Gaffney, P.J. Privitera, H.B.Daniell, E.E. Bagwell, J.G. Webb); analytical and synthetic chemistry ofendogenous compounds and analogs (eicosanoids, peptides) with par-ticular emphasis on high mass range mass spectrometry of proteins andhigh resolution 2D NMR of calcium binding proteins (D.R. Knapp, J.Oatis, J.J. Vrbanac, T. Williams, S. Martin); estrogenic and otherregulatory mechanisims of hepatic P-450 isoenzymes (T. Walle); roles ofred cell proteins in hemolytic events (D.J. Jollow, V.F. Price); mecha-nisms of steroid regulated gene expression (D. Kurtz).

Recent NIH and other grants for the above indMduals includeapproximately $7,500,000 for: individual research grants; construction ofnew molecular biology, hybridoma and cell cuiure laboratories; clinicalresearch; and for the recruitment of additional cell and molecularbiologists, chemists and other physical scientists interested in innovativeapproaches to therapeutic objectives.

Stipends for U.S. citzens or permanent residents funded through anNIH-supported training grant, and special stipends are available for otherexceptional candidates via the College of Graduate Studies of theMedical University. Minority candidates are strongly encouraged toapply. Send resume, relevant transcripts and reprints, statement ofresearch interests and names of three references to: Dr. H.S, Margo-

lus, Dirctor, Postdoctoral Training Program, Departm of Celland MoWlculr Pharmecolgy and Experimentl Thrapuks, Me&dcal UniverIty of South Carolina, 171 Ashley Avenue, Chl ,

SC 29425. An Equal Opportunity Empioyer/Affirmative Action Employer.I

A driving commitment toward research anddevelopment is a standard by which AbbottLaboratories has become a S3.8 billion leader inthe medical products industry. Our expandingpharmaceutical division is constantly exploringnew areas of health care, developing productsthat are advancing the methods of treatment fora wide variety of disorders. Currentl, we seekthe following professionals:

GROUP LEADER-CARDIOVASCULARPHARMIACOLOGYThe Cardiovascular Research Division has aposition for a senior level pharmacologist withexperience in the area of hypertension as it relatesto drug discovery. The qualified candidate will beexpected to lead a group of 5-7 professionalsstudying the role of atrial peptides and otherpharmacological agents for the treatment ofcardiovascular disease.A Ph.D. specializing in pharmacology orphysiology with 3+ years of experience relatingto the action of antihypertensive agents isrequired. Candidates must possess extensiveknowledge in areas of cardiac physiology,hemodynamics and renal function. A workingknowledge of receptor pharmacology is desirable.Reply to Job # 1.

Ph.D. CARDIQVASCULARPHARMACOLOGISTAn immediate opening exists in the CardiovascularResearch Division for a senior researchpharmacologist with a minimum of 2 yearspostdoctoral experience. The candidate shouldpossess a working knowledge of thecardiovascular system with an emphasis on theAdrenergic Nervous System. Experience inreceptor pharmacology is desirable with someexpertise on the role and utilization of adrenergicagents for the potential treatment of variousdisease states. Reply to Job #2.

BS/MS PHARM.ACOLOGYRESEARCH ASSOCIATESThe individuals we seek will have at least twoyears postgraduate experience in conducting liveanimal hemodynamic experiments as well asgood surgical skills and a familiarity withphysiological recording techniques. A knowledgeof computers and statistical data analysis isdesirable. Reply to Job #3.Recognized by Dun's Magazine as one of thenation's five best managed companies for 1986,Abbott is committed to excellence throughoutthe company. We provide an exceptional salaryand benefits package, which includes profitsharing and stock retirement plan. And we'relocated in an attractive suburban area just 30miles north of Chicago. For confldentialconsideration, please send your resume withsalary history Indicatingjqb number, to:Patricia Handy, Dept. S/3-27. Abbott is anAffirmative Action tmployer.

A IBOTT"HEALTH CARE WORLDWIDE" -

Senior BiomedicalInformation ScientistThe Medical Research Division of American Cyan-amid Company is seeking an individual with aPh.D. in a relevant life science to contribute to theinterdisciplinary research, biomedical develop-ment and marketing efforts related to the biotech-nology and cancer programs.Responsibilities include conducting retrospectiveliterature surveys using modern information re-trieval systems and monitoring current publishedliterature for important research advances.Individuals with prior experience with on-linebiomedical information retrieval systems, substan-tial knowledge of information resources and goodcommunication skills will receive preferential con-sideration.Competitive salary and liberal fringe benefits are of-fered in this desirable suburban location 30 milesfrom New York City. Please reply in confidence to:Ms. Maureen Quigley, Professional EmploymentRepresentative.

American Cyanamid CompanyMedical Research DivisionLederle LaboratoriesPearl River, NY 10965An Equal Opportunity Employer m/f

HEADPEPTIDE SYNTHESIS GROUP

We are a young, dynamic, research-driven,result-oriented company, recognized as aleader in the field of peptide synthesis. Weare looking for an experienced solid-phasepeptide chemist to lead our peplide synthe-sis group at our East coast location.

You have experience and in-depth familiar-Hy with solid-phase peplide synthesis as wellas with peplide purification. You will lead anddirect a group of chemists and be responsi-ble for development and production of newpepfides.

Qualifications must include a Ph.D. and sev-eral years of working experience.

For fully confidential consideration, pleasesend your resume to: BOX 35, SCIENCE.

iI- I

-:-Join our expanding teamiStuart Pharmaceuticals, a division of ICI Americas Inc, is one of thenation's fastest growing pharmaceutical companies. During the pastdecade, we have tripled our sales, increased our product lines, and con-tinued to develop new drugs in our expanding research facility. To keeppace with this growth, we need clinical research professionals with pro-ven experience for the following career positions:Botatlstidlan-MS in Biostatistics or Applied Statistics. Knowledge

of computer applications, SAS and statistical software are a must. (Re-spond to Job '50)* Sr. Clinical Programmer Analyst-BS in Business, ComputerScience or Life Science Must be proficient in the use of SAS and have ex-perience supporting clinical research efforts. (Respond to Job '51)* Clinical Systems Analyst-MS in Biological Sciences or ComputerScience plus knowledge of NDA process and 3-5 years' clinical systemsexperience. (Respond to Job '52)* Clinical Programm-r-BS in Computer Science, Life Science,Business, or Math and programming experience. SAS knowledge pre-ferred. (Respond to Job '53)

Clinical Research Assoclate-BS in Biosciences or Nursing plusexperience in clinical research. Must be available for travel. (Respond toJob '54)* Clinical Data Assoclate-BS in Bioscience, experience in dataanalysis and computer operations. (Respond to Job '55)We offer highly competitive salaries, comprehensive benefits includinga unique investment plan and opportunity for future professional andfinancial growth.Please submit resume and salary history to Manager, ProfessionalEmployment. On the envelope, please indicate the Job ' to which youresponded.E3 Stuart Pharmaceuticals

A division of ICI Americas Inc.Wilmington, DE 19897Equal Opportunity Employer, M/F

SCIENCE, VOL. 235

National Institute of Mental HealthAlcohol Drug Abuse, and Mental Health Administration

Public Health Service

NEuRosCIENCEs RESEARCH BRANCHCenters for Neuroscience and Schizophrenia Program

Position Title: Coordinator, Centers for Neuroscience and SchizophreniaPrograr.

Grade and Salary: GM 13-14; $38,727-59,000. Candidates may be eligible forappointment in the Commissioned Corps of the U.S.Public Health Service.

Location: National Institute of Mental Health, 5600 Fishers Lane,Rockville, MD.

Qualifications: Ph.D. in a neuroscience discipline plus direct experiencein the conduct of neuroscience research, and/or M.D.degree with clinical experience in psychiatric disordersand direct experence in the conduct of neuroscience meacl

Responsibilities: The NIMH Centers for Neuroscience and Schizophrenia(CNS) program will provide for development and support ofresearch centers which combine basic neuroscience researchwith clinical studies of schizophrenia The program will fundmajor research efforts, either at single institutions ormultiple, geographically separate institutions. The coor-dinator will be responsible for planning, developing andadministering the prograrm

Further Information Dr. Ronald Schoenfeldon Program or NIMH, Room 11-105Position: 5600 Fishers Lane

Rockville, MD 20857(301) 443-1504

Further Information I Harrs, Personnel Specialiston Application 5600 Fishers Lane, Room 15C-18Procedures/or Rockville, MD 20857Submit SF-171 to: (301) 443-4826

MIMH IS AN EQUAL OPPOR7hVI7Y EMPLOYER

Universiteit van AmsterdamThe University ofAmsterdam seeks for the Laboratory of Environmental and Toxicological Chemistry applicantsfor the position of

professor ofenvironmenital chemistry (n/f)*Vacancynumber S. 2224.This position requires the candidate to:*teach courses at both BSc and MSc level and hold seminars in Environmental Chemistry*conduct, stimulate and coordinate research in Environmental Chemistry; present research topics ofthedepartment including the behaviour of chlorinated aromatic compounds in the environment-participate in the administration and organisation at departmental and (sub)faculty level*manage graqt and research contract acquisition.The candidate will be expected to have:*a strong teaching record*a distinguished research background proven by a PhD thesis and various publications-considerable organising qualities.The candidate is expected to have a good command ofthe Dutch language within two years of the appointment.

Gross salary depends on age and experiences and ranges from Dfl. 6,854.- to Dfl. 9,495.- per month (Dutch CivilServants Code).Persons interested shoud send their curriculum vitae, including a list of publications, quoting vacancynumber-within 3 weeks -to the Chairman appointments Committee, Prof. Dr. H. Poppe,vakgroep Analytische Chemie,Nieuwe Achtergracht 166,1018 WV Amsterdam, the Netherlands.*Women in particular are invited to apply.

I

1702

esearchScientistsARespnieRsac

Environment

Pioneernew applicationsin Biotehnology,

PathologyandPh&rmacologyfor Cardiovascular&CNS Research.As a research-driven company, Scherng-Ploughcan offer you the project responsibility, support andrecognition to stimulate your best ideas. Joining usin one of these new positions, you'll be part of anexpanding group of bold thinkers. At the forefront ofsome of today's most significant breakthroughs incardiovascular and CNS research.

O Cariovas sPcE01vSR. BIOCHEMIST Your background must includeexperience with growth factor receptor bindingmethods and cell proliferation as well as familiaritywith tissue culture and related atherosclerosis re-search techniques.SR. BIOCHEMIST-Experience in the regulationand measurement of lipoproteins and cholesterol inserum and tissues is required, as is understandingof the latest information on lipoprotein metabolism.SR. EXPERIMENTAL PATHOLOGIST-Requiresexpertise in histological evaluation of the bloodvessel wall in atherosclerosis.SR. VASCULAR BIOLOGIST-You must have astrong background in thie cellular physiology of theblood vessel wall in atherosclerosis arid thoroughfamiliarity with vascular cell culture techniques.SR. PHARMACOLOGIST/PHYSIOLOGIST-Yourexpertise must encompass experimental animal

models of atherosclerosis and evaluation of drugeffects on atherosclerotic processes in vivo.El CNSirm logySR. CNS BIOCHEMIST-You must have compre-hensive knowledge of the application of fundamen-tal methods to new drug discovery. Preference willbe given to candidates with a background in any ofthe following: radioreceptor binding assays, HPLCand RIA assays for neurotransmitters and secondmessengers (cAMP and Pl), enzyme kinetic tech-niques, arid central dopaminergic and cholinergicpharmacological systems.Candidates for all positions must have a Ph.D., orequivalent, and 0-5 years' experience within thearea of interest. The ability to communicate andproduce results in an interdisciplinary environmentis essential.ASSISTANT/ASSOCIATE PHAAMACOLOGISTS(9 positions)-l n addition to the above positions,Schering-Plough is accepting resumesfor Assistant/Associate Scientists, to complement the Seniorpositions listed above. Forthese positions, interviewswill not begin until June or July of this year.We offer a competitive salary and outstanding bene-fits. Please send detailed resume, indicating positionof interest, to: Louis DeMartino, Schering-Research,60 Orange Street, Bloomfield, NJ 07003. We are anequal opportunity employer.

,3 ScherIn o>D~~~~~~Scering-Ploug

.M

POSITIONS OPEN

POSTDOCTORAL POSITIONSNational Institutes of Health

National Institute of Allergy andInfectious Diseases

Laboratory of Persistent Viral DiseasesRocky Mountain Laboratories

Positions available to study pathogenesis ofviral diseases,with particular emphasis on infections of the CNS orhemopoietic system. Models currently being studiedinclude rabies, murnnc, equine, and human retroviruses,Aleutian mink disease, and the scrapie agent. Approachesinclude use ofmolecular biology, genetics, and immunol-ogy. Applicants must have less than 3 years professionallevel relevant postdoctoral research experience and havecompleted their Ph.D., M.D., D.V.M., or equivalentdegree. Beginning salaries range from $20,000 to$23,000. Submit curriculum vitae, bibliography, andnames of three poteniial references to:

Dr. Bmce Chesebro, ChiefLaboratory of Persistent Viral Diseases

Rocky Mountain LaboratoriesHamilton, MT 59840

An Equal Opportunity Employr.

POSTDOCTORAL POSMON INDEVELOPMENTAL BIOLOGY

A position is availabk to study the biochemistry and cellbiology of rodent trophoblast cells Background in pro-tein chemistry and immunological tcchniques is desir-able. Send curriculum vitae and the names and addressesof three references to:

Dr. Michael J. SoaresDeprtent olf Physiolog

University ofKansas Medical Center (IUMC)Kansas City, KA 66103

KUMC is an Affinatv Action/Equal Opportunity Em-ployer

POSTDOCTORAL POSITONIN NEUROBIOLOGY

Available in the Department of Pharmacology, St.Louis University School ofMedicne, St. Lous, Mis-souri. This NIH-funded project will use single electrodcvoltage-damp recordings from neurons within intactautonomic ganglia to study the role of ncuroactivcpeptides in avian oculomotor neurotransmission. Theapplicant must have a strong background in intracrllularelectrophysiological techniqucs, and experience withvoltage-dlamp is preferrcd. Send curriculum vitae along

with names of three references to: Vincent A. Chia

nelli, Ph.D. (on sabbatical leave until September, 1 7)

at MRC Moleclar Neurobiology Unit, Universit of

Cambridge Medical School, Hills Road, Cambrdge

CB2 2QH, Great Britain. St. LouisU ir an

Equal Opportunity Employer. MIFIVIIl.

POSTDOCTORAL POSMIION, YEAST MOLEC-ULAR GENETICS/GENE EXPRESSION, availableimmediately. Recombinant DNA methods are beingused to characterize the DNA binding protein which

activates transcription of the maltose fermentation genesin the Saccharorces yeasts. The work involves mutantisolation, DNA-protem binding studies, antibody prepa-ration and DNA sequencing. Experience in moleculargenetics is required. S4alry range is $18,000 to $20,000(plus benefits), depending upon experience. Please sendcurriculum vitae, copies of relevant reprints and names ofreferences to: Dr. (Cinne Michels, Department OfBioogy, Queens College of the City tTnversit ofNew York, FhPhing, 11367

RESEARCH PROGRAMMER needed to modify,document, develop production codes, and to evaluatealgorithms for scientlfic applications. Initial assignmentwiUl be in molecular modeng and dynamics of biopoly-mers. Experience in this field or in supercomputcr use is aplus. Wide scientific interest, god commumcation skills,and graduate degree require Subnmit resumes to: JohnAndcws, Computer Center n/c 135, Univrusity ofIlinois at Chicago, Chicago, IL 60680-4348. Affir-m&teAction/Equal Opportunity Employer.

1704

POSTDOCTORAL POSMIION available September1987 for a BIOCHEMIST, CELL BIOLOG-IST, orDEVELOPMENTAL BIOLOGIST to study cellularadhesion and membrane proteins as cellular determi-nants. The project will include isolation, purification,and structural analysis of glycoproteins contributing toadhesion of cells in sea urchin embryos. Contact: Dr.Merrill B. Hille, Department of Zoology NJ-15,University of Washingn, Seat WA 98195. Tcle-phone: 206-543-5781

POSTDOCTORAL POSMON availabic for work onthe pathogenesis of neurodegenerative and seizure disor-ders. Experience with modern biochemical and/or(immnuno)histochemical techniques essential. Back-ground in the neurosciences desirable. Starting date onor after 1 July 1987. Send resume and names of at leastthree references to: Robert Schwarcz, Ph.D., MarylandPsychiatric Research Center, P.O. Box 21247, Balt-more, MD 21228.POSTDOCTORAL POSMON to study the cellulrand molecular biology ofthe neuronal cytoskeleton, withemphasis on expression of microtubule-associated pro-teins in brain. ork will involve isolation and analysis ofcDNA, in situ hybridization, and neuronal cultures.Applicants should have a Ph.D. and background inmolecular biology. Experience in neuroscience, or tissueculture is useful. The position carries a Harvard MedicalSchool appointment and is for 3 years beginningin April1987. Send curriculum vitae to: Dr. Itzhak Fischer,Deprtment of Biochemistry, E. K. Shriver Center,200 Trapelo Road, Waltham, MA 02254.POSTDOCTORAL POSMIION to study the molecu-lar biology of cell adhesion proteins and their receptors.The project will focus on new approaches to understand-ing morphogenesis. While experience is desirable, we willgladly train an interested individual in recombinantbNA, solid phase peptide synthesis, and biophysicalmethods. Send sununary of research, curriculum vitae,and references to: Dr. Robert J. Klebe, Department ofCelluar and Stuctural Biology, Univcrsity of TcxasHealth Science Center, San Antonio, TX 78284. AnAffirmatip ActionEqgual Opporunity Etployer.

POSTDOCTORAL POSMIION-available immedi-ately to study the immunosuppressive activity ofStaphy-lococcal Exotoxins. Positions exist for research dealingwith both immunoregulatory cell activity as well asfundamental protein biochemistry. Send curriculum vitaeand three letters of reference by 10 May 1987 to: Dr.Ihomas J. Rogers, Associate Professor, Departmentof Microbiology and Immunology, Temple Universi-tySchoolofMedicin, 3400 North Broad Street,

PA 19140. Equal Opportunity Employr.POSTDOCTORAL POSITIONIN MOLECULAR BIOLOGY

To study the biochemical regulation and interactionsof the c-sn protooncogene product. Studies includerecombinant DNA, tissue culture, and protein analysistechniques. Relevant experience is desirable. Contact:Dr. David Shalloway, Department of Molecalar andCell Biology, Ihe Pennsylvania State University,Room 406 South Frear, Univcrsity Park, PA 16802.Equal OpportunitylAffinnativeAction Employr.POSTDOCTORAL POSITION AVAILABLE

Position available immediately to study the structures ofdamaged DNA and of DNA repair and recombinationenzymes, the action mcchanisms of the repair enzymesusing electron microscopy and genetic engineering tech-niques. Molecular biology background is required. Sendapplication to: Drs. Jack Grith and Azi Sancar,University of North Carolina School of Medicine,

tof Biochemistry 231H, Chapel Hil, NC254 qual Oppotnsey/Affirmativectin Employer.

POSTDOCTORAL POSITION availabk to investi-gate the role of purine receptors in respiratory control inthe newbom rat. Expericnce in small animal surgery,brain anatomy, and knowledge of receptor biochemistryis desirable. A Ph.D. in pharmacology or physiology ispreferred. The yearlyr salary is $18,00 for a period of2½to 3½2 years starting June 1987. Send curriculum vitaeand three letters of reference to: Dr. H. Ronald Ziclke,Pediatric Research, Univcrsity of Maryland, 655West Baltimore Stree, Baltimore, MD 21201. AnEqual OpportunitylAffinative Action Employer.

i| WJug

The Savannah River Plant Offers Two ClearAdvantages: Career Challenge And Our

Location In Aiken, South CarolinaOperated by Du Pont for the United States Department of Energy, the Savan-

nahRiver Plant produces radioactive isotopes for national defense, medicine, andAmerica's space program. While this outstanding environment broadens your pro-fessional horizons, our Aiken, South Carolina location provides access to someof the Southeast's most attractive cultural and recreational resources. Positions areavailable for:

Air Quality EngineerMS/PhD in Meteorology or Engineer-ing, with emphasis on air quality pro-tection, plus a minimum of 2 years ex-perience. Position requires keeping up-to-date on regulations and newtechnologies in air quality monitoringto provide for implementing air quali-ty protection plans.

Aquatic Ecologist MS/PhDin Aquatic Ecology/ Biology, as well as3 or more years experience, includingNPDES permitting, biomonitoringstudies and bioassay testing. Assign-ments would include developingresource management programs forsurface waters and wetlands, and coor-dinating regulatory complianceactivities.

These positions may require physical activity such as climbing ladders and theuse of respiratory protective equipment. U.S. CITIZENSHIP REQUIRED.Salary is commensurate with your training and

expesrence. Our highly regarde efits program _ iincludes relocation assistance. For confidential 00consideration, please send resume, indicatingposition of interest, to: K.L. Mays, EmployeeRelations Department, Room X50654, Du Pont tcus vaTM"Company, Wilmington, DE, 19898. Ant Equial Opportun1ity Employer MIF

POSIlrIONS OPkNPOSITIONS OPEN

APPLICATIONSCIENTIST

Main Responsibilities:Training of and technical sup-port to customers in the use ofa microscope - based medicalimage analysis system.Must have experience andknowledge in the use of com-puters (preferably IBM PC) andbackground in biology or lab-oratory medicine. Some un-derstanding of imaging sci-ence preferred. Excellent inter-personal skills required. Moder-ate travel.Negotiable starting salary de-pending on qualifications.Please send your resume inconfidence to:

Yvonne V. IasaaPeronnel Department

CELL ANALYSIS SYSTEMS261 Eisenhower Lane South

Lombard, IL 60148AN EQUAL OPPORTUNITY EMPLOYER

PAC mmmm--__ BIO

Pacific Biotechnology Ltd. is a newly formed Australian joint venture betweenCalifornia Biotechnology Inc. and the Garvan Institute of Medical Research. Pac Bio willbe located in Sydney and will primarily be concerned with the development of newhuman therapeutics for diseases of aging, especially cardiovascular disease, os-teoporosis and inflammatory disorders. The company will focus on techniques ofmodern molecular and structural biology and chemistry.

Applications are invited from scientists at all levels in any of the following researchareas to fill a variety of new positions:

Receptor cloning and biochemistry

Synthesis of peptide analogues

X-ray crystallography

NMR spectroscopy

Computer modelling

Organic chemistry

Pac Bio intends to commence operations in mid-1987. Interested candidatesshould send a resume and names of two references to: California Biotechnology, Inc.,Human Resources Department, Attn: MF:ebp, 2450 Bayshore Parkway, Mountain View,CA 94043. We are an equal opportunity employer.

The Basic and Applied Science division of Bionefics Research, Inc. isseeking a qualified Ph.D. level Scientist and experienced Technicians tosupport its efforts in the basic research and development of diagnostictools, vaccines and therapeutic agents for HTLV-11l and related humanretroviruses.SCIENTIST 11/111- Molecular virology, Ph.D. in Molecular Biology or Bio-chemistry with a minimum of two years experience in recombinant DNAtechniques including expression of retroviral genes.SENIOR LABORATORY TECHNICIANS- Propagation of retroviruses,tissue culture, immunological and biochemical procedures for characteri-zation of retroviral proteins. MS/BS in Biology, Immunology or Biochemis-try with two or more years experience.Bionetics Research, Inc. is located in suburban Washington, D.C. andprides itself in offering a comprehensive benefits package, which includes401 (K) Savings Plan with company matching funds, health, life and dentalinsurance paid for employees and competitive salaries.Please send Curriculum Vitae including salary history to: HumanResource Office-Pos. A, BIONETICS RESEARCH, INC., 1 330-A PiccardDrive, Rockville, Maryland 20850. BRI is an Equal Opportunity Employer.All applications welcomed.

I BIONETICS RESEARCH, INC.

a

CHAIR, DEPARTMENT OFANATOMICAL SCIENCES

City University ofNew York Medical School

Applications and nominations are invited forthe Chair of a new Department of Anatomi-cal Sciences at CUNY Medical School. TheSchool has a special obligation to empha-size the significant emerging role of primarycare as well as to increase the number ofphysicians in underrepresented minoritiesin the nation's physician pool and to en-hance the availability of medical services tounderserved areas.

Candidates should be recognized as out-standing in research, have strong teach-ing credentials and have administrativestrengths. Salary competitive and commen-surate with experience. Please send lettersof application or nomination, curriculumvitae and the names, telephone numbersand addresses of three references by May1, 1987 to: Dr. Meir Lev, Chair, SearchCommittee for Anatomical Sciences, CityUniversity of New York Medical School

.~.CITY COLLEGE OF CUNY4--Se.R Convent Av & 138 StG 8.INew York, NY 10031

An AAtEO Employer M/F

r

L

NPOSITIONS OPEN

POSTDOCTORAL POSMON available immediate-ly to study initiation of DNA replication in eukaryoticcells. A newly developed technique is being used toidentify and characterize chromosomal replication on-gins in yeast and Droshda, and to explore the relation-ship between replication and transcription in these orga-nisms. Proteins involved in initiation of replication arealso being identified and characterized. A competitivesalary is offered. Please send curriculum vitae and havethree letters ofrecommendation sent before 1 May 1987,to: Dr. Joel A. Huberman, Department of Molecularand Cellular Biology, Roswelf Park Memorial Insti-tute, Buffalo, NY 14263. Telephone: 716-845-3047.An Equal OpportunitylAffirmantve A n Employer.

POSTDOCTORAL POSMIION: Availabk spring1987, University of California, San Francisco(UCSF). To study the structure and function ofpolypep-tide hormone receptors. Requires background and inter-est in protein purification, immunology, and peptidechemistry. Experience with HPLC and hybridoma tech-niques preferred. Send curriculum vitae and names ofthree references to: Dr. Carl Grunfeld, MetabolismSection (1l1F), VA Medical Center, 4150 ClemcntStreet, San Francisco, CA 94121. UCSF is an EqualOpportunity/Affirmative Action Employer; womcn and mi-nonties arc cncouragcd to apply.

GLYCOPROTEIN/CARBOHYDRATEBIOCHEMIST

POSTDOCTORAL POSITION available for persontrained in glycoprotein and/or carbohydrate biochemis-try (particularly chromatographic methods for sugars,oligosaccharides, and glycopeptides) to participate inongoing research concerning the role of protein glycosy-lation in photoreceptor membrane morphogenesis andretinal degenerations. Send curriculum vitae, recent re-

ints, and names of three references to: Dr. Steven J.Pliesler, Bascom Palmer Eye Institute, University ofMiami School of Medicine, P.O. Box 016880, Mi-ami, FL 33101.

POSTDOCTORAL POSMON available immediate-ly to study the molecular biology of novel calcium-binding proteins in African trypanosomes. An interest incellular regulatory pathways and some experience withrecombinant DNA techniques is desirabk. Send curricu-lum vitae to: Dr. Larry Ruben, Department of Biolo-gy, Southern Methodist University, Dallas, TX75275. Equal Opportunit/Affirmative Action Eqployer.

POSTDOCTORAL POSMON now available forperson experienced in recombinant DNA technology orbiochemistry. Opportunity to participate in study oftransmembrane signal transduction involving phosphoinositides. Send curriculum vitac and names of threereferences to: Dr. 0. Hayes Griffith, Institute ofMolecular Biology, University of Oregon, Eugene,OR 97403. UO is an EqZ OpportunitylAffirmativeAction Emplyer.

POSTDOCTORAL POSMON availabk immediate-ly to study the regulation of cnzymcs which mediatestimulus-response coupling in mammalian cells. Projectsinclude the purification, cloning, and expression ofmam-malian intracellular phospholipases and studics on thetranscription, translation, and intracellular processing ofthese enzymes. Candidates should be recent Ph.D.'s withexperience in molecular biology and/or protein chemis-try. Send curriculum vitae and two letters of recommen-dation to: R W. Gross, M.D., Ph.D., Box 8020,Washington University, St. Louis, MO 63110.

POSTDOCTORAL POSMIIONHEPATIC MEMBRANE TRANSPORT

Postdoctoral position available for NIH-funded projectinvolving characterization and isolation of hepatic mcm-brane proteins mediating bile acid and calcium transport.Applicant must have recent Ph.D. and previous experi-cnce in vesicle transport or protein purification tech-niques. Send curriculum vitae and narnes of three refer-ences to: Bennett L Blitzer, M.D., Liver Study Unit,University of Cincinnti College of Medicine, 231Bethcsda Avenue (Room 6560), Cincinnati, OH45267.

POSTDOCTORAL POSMONIN ENDOTHELIAL PATHOPHYSIOLOGY

Available immediately for 2 to 3 years, to study thebehavior and responses of endothelial cells from varioussources under conditions of tissue culture, as part ofongoing studies on micro- and macro-vascular patholo-gy. Candidates should have a Ph.D. in cell biology orbiochemistry, and experience in tissue culture. Pleasesend curriculum vitae and names of three references to:Dr. Guido Manjo, Dcpartment ofPathology, Univer-sity of Massachusett Medical School, 55 Lake Ave-nue North, Worcester, MA 01605.The Unrst ofMassachusetts is an Affirmative AtionlEqual Opportunty Employer.

POSTDOCTORAL-RESEARCH ASSOCIATES.Several positions are available with negotiable startingdates to join an integrated and ongoing research programon growth factors and their mechanism of actions. Wearc seeking candidates with training in one of the follow-ing areas: (i) Pharmacology experience in xcperinentaldesigns for effector and inhibitor for receptor binding.(ii) Immunology experience in RIA/ELISA and meth-ods to purify mono-polydonal antibodies. (iii) Peptideand protein chemistry. Please send curriculum vitae andinqury to: James Tam, Rockefeller University, Box294, 1230 York Avenue, New York, NY 10021. AnEqual Opportunity Employer.

POSTDOCTORAL RESEARCH ASSOCIATE. Po-sitions are now available to join a multidisciplinary groupstudying the structure and regulation ofthe genes for thecatecholamine neurotransmitter biosynthetic enzymes.Applicants should have a strong background in eitherrecombinant DNA technology or neurochemistry/neuro-pharmacology. Send curriculum vitae, statement of re-search interest, and the names of three references to: Dr.Barry B. Kaplan, Molecular Neurobiology Program,Western Psychiatric Institute and Clinic, Universitof Pittsburgh School of Medicine, Pittsburgh, P15213.

PostdoctoralFellow/Scientist

California Biotechnology Inc., a rapidlygrow-ing biotechnology company engaged in the devel-opment of diagnostic and therapeutic products isseeking an outstanding individual to join itsMolecular Genetics group.

Qualified candidates must have a Ph.D. and0 - 2 years postdoctoral experience in the fields ofMolecular Biology, Human Genetics and Statistics.The applicant will have demonstrated scientificcreativity and ability to interact well with others.

We offer a stimulating research environmentwith a competitive compensation and benefits pack-age. For consideration please forward curriculumvitae and names of three references in confidenceto: California Biotechnology Inc., Human Resources,Dept. MF-PF, 2450 Bayshore Parkway, Mountain V'iew,CA 94043. An equal opportunityemployer.

CAL--- BIG

BUILDING ANEW LAB?

LET THE SCIENCE FREE PRODUCTINFORMATION SERVICE PUT YOU INTOUCH WITH THE VENDORS WHOSEPRODUCTS YOU WILL NEED.

SIMPLY WRITE US A LETTER STATINGTHE SPECIFICS ABOUT YOUR PROPOSEDLAB AND WE WILL DO THE REST.

WRITE TO:

SCIENCE MAGAZINENEW LAB SERVICE DEPT.1I515 BROADWAYNEW YORK, N.Y. 10036

POSITIONS OPEN POSITIONS OPEN

OPPORTUNITIES

AT BOENRINGER

MANNHEIMBoehringer Mannheim is a rapidly growing leader inthe field of medical diagnostics and biochemicals.This leadership has been attained through empha-sis on quality and team effort and it's BoehringerMannheim's employees that are responsible forgrowth and leadership. Due to this growth, we arecurrently seeking qualified individuals for excep-tional opportunities in the following areas:

RESEARCH INVESTIGATOR-TEST DEVELOPMENT

Will coordinate and conduct research and develop-ment of clinical chemistry diagnostic tests in novelformats from initial laboratory experiments throughscale-up and evaluation to transfer into production.Requirements include a PhD or equivalent experi-ence in Biochemistry, Chemistry or related area andproven research and development experience in testdevelopment preferably in an industrial setting. Ef-fective oral and written communication skills and su-pervisory skills are also essential.

RESEARCH INVESTIGATORANALYTICAL

Responsibilities include developing specificationsand analytical procedures for characterization of rawmaterials and finished products with regard to theircomposition, reactivity, enzyme activities and stabil-ity. Also will coordinate and develop in process qual-ity control procedures. A PhD in Analytical Chemis-try, Biochemistry or equivalent and knowledge of awide variety of analytical instrumentation is required.Effective oral and written communication skills andsupervisory skills are also essential. Expertise withpolymers would be a definite plus.

RESEARCH INVESTIGATOR-TECHNOLOGY DEVELOPMENT

Will conduct research in new technologies directedtoward test development in novel formats. Will alsoprovide an interface between test developmentscientists and engineers to develop instruments andequipment to bring new technologies on line. A PhDin Chemistry, Biochemistry, Physics or an MS inChemical Engineering or equivalent experience isrequired. Effective oral and written communicationskills are also essential. Experience with film tech-nology is a definite plus.

RESEARCH INVESTIGATOR-IMMUNOASSAY DEVELOPMENT

Will coordinate and conduct research and develop-ment of immunodiagnostic tests in novel formatsfrom initial laboratory experiments through scale-upand evaluation to transfer into production. Require-ments include aPhD orequivalent experience in Bio-chemistry, Chemistry or related area and proven re-search and development experience in test develop-ment, preferably in an industrial setting. Effective oraland written communication skills and supervisoryskills are also essential.

SCIENTISTSThese positions will support the above personnelwith requirements including B.S. or M.S. in Biology,Chemistry, Biochemistry, ImmunochemistryorAna-lytical Chemistry and at least one year of applicableR&D experience.At Boehringer Mannheim we offer an exciting andchallenging work environment as well as an excel-lent compensation and benefit program including a401K. If you meet the above requirements and wouldlike to join an organization that is a leader in itsfield, we invite you to send your resume with salaryhistory to:

HUMAN RESOURCESBOEHRINGER MANNHEIM

Department S * P.O. Box 501009115 Hague Road * Indianapolis, IN 46250

I

The Bionetics Research, Inc. Internal Research and Develop-ment Program is expanding its biotechnology initiativesrelated to diagnostic products and cancer vaccines. We seekindividuals at the Ph.D. and MS levels with established creden-tials to support these on-going projects. Experience applicableto one or several of the following areas is required:Monoclonal Antibody-generation against tumor antigensusing hybridoma fusion techniques.Cancer Biology/Immunology-related to the immunopharma-cology of lymphokines.lmmunohistochemkcal/Flur methodology to eval-uate monoclonal antibody tissue reactivity using Radiobindingor EUSA methods.Molecular Biolgy-research in genetics of gene expressionin Ecoli Eukaryote gene cloning. Development and applicationof expression vectors, construction and analysis of cDNA andgenetic libraries and DNA cloning and chemistry.Biochemsry-protein sequencing, amino acid analysis, pro-tein purification and characterization.Diagnostc Immunology-using monoclonal antibodies forbacterial and viral pathogens and cancer antigens.MonocInal Antibody-production and purification in largescale, using ascites production as well as in vitro methods.Radiolodinaltn Chemisty-using 1251 to label proteins andsmall molecules (cAMP), and to design RIA procedures.These are attractive opportunities for scientists and techni-cians interested in basic research, biotechnology, and tech-nology transfer.Comprehensive compensation package includes paid medi-cal/life/dental insurance premiums for employee, and 401 (K)savings plan with company matching funds.Please send Curriculum Vitae, including salary requirementsin confidence to:

Human Resource Department-ScienceBIONETICS RESEARCH, INC.

1 330-A Piccard DriveRockville, Maryland 20850

BRI is an Equal Opportunity Employer.All applicants welcomed.

* BIONETICS RESEARCH, INC.

IBOEHRINGER IMANNHEIMOIAGNOSTICS

An Equal Opportunity Employer

a

POSITIONS OPEN

POSTDOCTORAL POSMIION IN IMMUNO-BIOLOGY OF CANCER Ribi ImmunoChem Re-search, Inc., Hamilton, Montana, has immediatelyavailable a postdoctoral position to perform basic andfundamental studies regarding immunobiolo$y of can-cer. Applicants should have previous expenence withtumor-associated antigens, therapy of tumors in experi-mental animals, immunoassays and analysis of immuneresponse data. The beginning salary is $20,000 for 1 yearand may be extended for a maximum of one additionalyear if approved by the arch staff and management.Motivated and creative individuals soon tO be awarded orholding recent Ph.D., M.D., D.V.M., or equivalentdegrees are invited to apply. Send curriculum vitae andlist of three references to: Dr. John L. Cantrell, ChiefofImmunology, Ribi ImmunoChem Research, Inc.,P.O. Box 1409, Hamilton, Mont , 59840, tele-phone 406-363-6214. An Equa Opportunity Employer.

POSTDOCTORAL POSMONTUMOR VIROLOGY

Available immediately, we have recently discoveredRNA covalently bound to SV40 TAg and to the onco-gene product p53. The RNAs, the bondin%, and thepossiblesigicance to oncogenic transformation will be

citizenship or residency required, fundingthrough NIH training grant. Send curriculum vitae andnames of three references to:

Dr. Robert CarrollDvrnnof Pathology

New rntyM ediaSchool550 First Avenue

New York, NY 10016

POSTDOCTORAL'RESEARCH ASSOCIATE towork on the immunogenetics of the acute leukemias inrapidly expanding Medical Center. Project involves someknowledge of CGg and Raji cell assays, agarose blockclectrophoresis, SDS-polyacrylamide gel clectrophore-sis, and clectroblotting (Western blot). Experience withmonoclonal antibodies desired. Work would involveclose collaboration with molecular biologist and hema-tologist. Send curriculum vitae, and three letters ofrefcrence to: Dr. Harold R Schumacher, Departmentof Pathology, 2160 South First Avenue, Loyoh Uni-versity Medical Center, Maywood, IL 60153. LyolaUniversy is an Equal Opportunity Employer.

LABORATORY/HEMATOLOGY FELLOWSHIP.Loyola University Medical Center ofChicago is estab-lishing a new program in laboratory hematology forpathologists Board-certified in AP and CP. Internists andpediatricians with comparable Boards interested in morern-depth training in hematology will be considered. Theprogram will be broad based and directed toward sub-specialty Board certification with training in coagulation,peripheral blood analysis, and bone marrow pathologydunng the first year. The second year will be devotedprimarily to research. Interested candidates should send acurriculum vitae and names of references to: Dr. HaroldSchumacher, Prosor and Chief of Heratokgyr, D-parmcs i of Pathokogy, Loyola UnWierty Midkl

2r,2160 SouthPirst Aveue, Maywood, IL60153. Loyoa Unieity is an Equal Oppotunity Empioyer.Individuals with doctorate degree, background and expe-rience in metallothionein, immunochemistry, and mofec-ular biology are being sought to fill two POSTDOC-TORAL RESEARCH ASSOCIATE POSMONS.Send curriculum vitae, a statement of career goals, andthree letters of recommendation to: Dr. . Ebadi,Professor and Chairman, Department of Pharmacol-ogy, University of Nebraska College ofMedicine, 42Street and Dewey Avenue, Omalh, Nebraska 68105.AffimativeAction/Equal Opportunity Employer.

POSTDOCTORAL/SENIOR RESEARCH ASSO-CIATE position available immediately to study proteinsorting in the nervous system. Studies will utilize a multi-discipinary approach to examine cellular and molecularmechanisms responsible for the delivery of proteins byfast axonal transport. Candidates should have a strongbackground in protein chemistry and/or molecular biolo-gy. This opportunity offers potential advancement into apermanent independent staf position. Send curriculumvitae and names of three references to: Dr. GeorgeStone, Division of Molecular Biology, Nathan KlineInsitute, Orangeburg, NY 10962. Equal OpportunityEmployer MIF.

1708

POSTDOCTORAL RESEARCH POSITION avail-able in the laboratory of an NIH-trained investigatorinterested in complement, cellular immunoregulation,and leukocyte metabolism. Experience in cellular andbiochemical techniques, protein chemistry, monoclonaldevelopment, and/or ELISA techniques is preferred butnot essential. Send curriculum vitae to: Dr. ChaimBrickman, Center for Ccll Biology, Sinai Hospitalof Detroit, 6767 West Outer Drive, Dctroit, MI48235- 2899.

RECEPTORS AND G-PROTEINSAn opportunity for POSTDOCTORAL TRAININGwill become available July 1987 in a group investigatingthe cell biology, biochemistry, and molecular biology ofcell-surface receptors and the G-proteins to which theyare linked. Ph.D. or M.D. required, experiencc germaneto these pursuits highly desirable. Send cumculum vitaeand names of three references to: Dr. C. C. Malbon,Department of Pharmacology, Health Science Cen-ter, SUNY/Stony Brook, Stony Brook, Long Island,NY 11794-8651.

RESEARCH ASSISTANT: Sloan-Kettering Institute.We seek a qualified individual for a biomedical technicalsupport position to participate in projects which focus onthe development of anti-cancer therapies utilizing amultidisciplinary approach. Extensive hands-on experi-ence in molecular biology is essential; a thorough work-ing knowledge of biochemistry a must. B.S./B.A., plus 3years of relevant bench research experience required. Weoffer an excellent compensation package, a state-of-the-art working environment, and an excellent opportunityfor career development. Please send r6sumd to: E. L.Kldnert, Personnel Department #060, MemorialSloan-Keteri Cancer Center, 1275 York Avenue,New York, NY 10021. An Equal Opportunity Employer,MIFIHIV.

RESEARCH ASSOCIATEEmployer seeks person with Ph.D. in electrical engineer-ing and2 years of experience to direct advanced researchon fast-structured a[gorithms for statistical signal pro-cessing. Required: a thorough knowledge of the theoryof non-stationary lattice-filter models and their role inlinear estimation, filter synthesis, inverse scattering,adaptive filtering, and computational algebra, as well as adeep understanding of network theory, matrix theory,and systolic array implementation. Salary $52,000 perannum. Job site: Stanford. Send this ad and a resume to:Job number CW1278, P.O. Box 9560, Sacramento,CA 95823-0560 not later dtan 13 April 1987.

RESEARCH ASSOCIATE available for a Ph.D. inphsiology/cell biology to join a group studying theclular regulation of transport processes in airway epi-thleia. Applicants must havc cxperience in either quanti-tative fluorescence microscopy or electrophysiology andshould be willing to master both techniques. Inquesto: Dr. C. 1Vjilam Davis, Division of PulmonaryDiseases, Universit of North Carolina, Chapel Hill,NC. Telephone 919-966-2531. An Equal OppeunityAffirmativ Aation Employer

RESEARCH ASSOCIATE position available immedi-ately to study the regulation and enzymologyofsphingo-lipid synthesis. Ph.D. in biochemistry with 3 years ofpostdoctoral cxpericncc in sphingolipid analysis re-quired. Some experience in microbiology preferred. Sala-ry $22,000 per year, 40 hours per week. Apply to: Dr.M. Lev, Assocate Dean for Basic Sciences, CityUniversity of New York, Medical School, 138 Con-vent Avenue, New York, NY 10031. An Equal Oppor-tunitylAffinnative Actim Employer.

RESEARCH ASSOCIATEPOSTDOCTORAL FELLOW

Research associatc/postdoctoral position available im-mediately to join multidisciplinary group engaged ininsulin growth factor action. Project involves puricationand characterization of growth factor-stimulated P-tyrproteins. Strong background in monoclonal antibodiesand experience with protein peptide purification re-quired. Protein microsequencing, oligonucleotide andpeptide synthesis available via adjacent core laboratory.Send curriculum vitae and three letters of reference to:J. Avruch, Chief, Diabetes Unit, Massachusetts Gen-eral Hospital, Boston, MA 02114 or tdelphone: 617-726-6909.

The University of Adelaide South Australia invitesapplications from both women and men for a RE-SEARCH ASSOCIATESHIP available immediatelyfor up to 2 years in the DEPARTMENT OF BIO-CHEMIS7TRY, at the Waite Agricultural Research Insti-tute. A molecular biologist is required to work on aproject funded by a grant under the Australian ResearchGrants Scheme to analyze the molecular structure of aplant chromosome. The study will concentrate on chro-mosome 1 of rye using wheat/rye addition lines. Thework involves the use of recombinant DNA techniquesand other DNA analysis procedures in conjunction withcytogenetic and cell culture methods.

Applicants should hold a Ph.D. degree and haveexpenence in molecular biology or genetics.

Further information may be obtained from: Dr. P.Langridge, Department of Agricultural Biochemis-tri, (08) 372 2368. Annual salary: A$24,013 x 5 to

Applications in duplicate, quoting reference number4697, giving personal particulars (induding whethercandidates hold Australian permanent residency status),rcsume, and names and addresses ofthrec referecs shouldreach: The Registrar, University of Adelaide, GPOBox 498, Adelaide, South Australia, 5001, TelcxUNIVAD AA 89141 not later than 20 April 1987. TheUniventy is an Equal Opportunity Employer.

RESEARCH PSYCHOLOGISTSUNNYBROOK MEDICAL CENTRE

TORONTO, CANADASunnybrook Medical Centre is an 1180-bed University

of Toronto teaching hospital with major programs inTrauma, Oncology, Diseases of the Aging, and MentalHealth. The Medical Centre is located on 200 acres ofparkland in the heart of Metropolitan Toronto.Sunnybrook seeks an academic psychologist with pri-

mary responsibility for the promotion of research withinthe Departmnent of Psychiatry. It is expected that thecandidate selected will receive a cross appointment to theUnivcrsity of Toronto.Apply to:

Dennis J. EganChairman, Search CommitteeSunnybrook Medical Centre

2075 Bayview AvenueRoom C-1430

Toronto, Ontario M4N 3M5

AMERICAN BIOGENEFICSRESEARCH SCIENTIST

American Biogenetics Corporation, specializing inthe genetic engineering and iodesign of microorga-nisms which produce specialty chemicals, has a positionavailable for a highly motivated MICROBIAL/YEASTGENETICIST/PHYSIOLOGIST. The successful ap-plicant must possess a Ph.D. and have at least 2 years ofpostdoctoral training.American Biogenetics Corporation offers a challenging

and creative working environment, and excellent oppor-tunities for personal and scientific development, and islocated in a desirable coastal area ofsouthern California.Send curriculum vitae and the names of three refer-

ences to: Robert Little, Ph.D., American BiogencticsCorporation, 19732 MacArthur Boulevard, Suite130, Irvine, CA 92715, no later than 24 April 1987.

RESEARCH SCIENTISTSBIOGROWVTH, INC.

BioGrowth, a new biotechnology company, has open-ings for the following scientists:MOLECULAR BIOLOGIST, Ph.D., with 2 years ofadditional experience in developing mammalian expres-sion systems including retroviral and dhfr-amp ablevectors.MOLECULAR BIOLOGIST, B.S./M.S., with 2 addi-tional years of lab experience including cDNA libraryconstruction, mRNA preparation/translation, DNA/RNA sequencing, and expression vector construction.BioGrowth, located in new facilities in the San FranciscoBay area, offers competitive salarics, benefits, and theopportunity to make a major contribution at a newlydeveloping company. Please send your r6sumi, salaryhistory, and list of three references to: BioGrowt, Inc.,Department MB-1, 3065 Atlas Road, Suite 117,Richmond, CA 94806.

SCIENCE, VOL. 235

POSITIONS OPEN POSITIONS OPEN

SEEN TI STSGenentech, Inc., a leader in the field of Biotechnology, seeks highlymotivated Scientists with demonstrated records of accomplishmentfor the following positions:

Process Research& DevelopmentWorking in tandem with an expertteam of biochemists and biochemicalengineers, you'll help develop andscale up methods for the purifica-tion/characterization of recombinantproteins and peptides to be used inhuman pharmaceuticals and animalhealth care products. Specific focusareas will Include recovery processesand rapid protein isolation/charac-terization, therefore knowledge ofHPLC, FPLC, affinity and other pro-tein purification/analysis techniquesis essential. Strong interest in immu-nochemistry, and the ability to thinkcreatively are also required assets.Successful candidate will have a PhDin Biochemistry/Biochemical Engi-neering and at least 2 years relevantpostdoctoral experience in academiaor industry. (#JG-2033)

Biological ChemistryYour responsibility will be to investi-gate basic mechanisms of action ofrelaxin and other proteins at themolecular and cellular level, as wellas develop cell-based assays whichreflect these bioactivities. Cell biol-ogy and biochemistry backgroundwith experience in cefl culture andreceptor binding techniques re-quired. Background experience withimmunoassay development and pro-tein receptor purification highly de-sirable.Successful candidate will have PhDin Cell Biology or related field and atleast 2 years related experience inacademia or industry. (#JG-2006)

Medicinal & AnalyticalChemistryPosition will supervise the testingand release of new products for clini-cal trials. The candidate we seek willhave creative abilities in proteih/peptide characterization, and theexpertise to establish and implementfinal product specs. This positionalso involves writing scientificreports in support of IND submis-sions, so excellent communicationsskills are essential.Successful candidate will have aPhD in Biochemistry or relatedfield and at least 2 years relatedexperience in academia or industry.Pharmaceutical experience highlydesirable. (#JG-1351)

Postdoctoral FellowBiochemicalEndocrinologyA Postdoctoral Fellow in BiochemicalEndocrinology is sought to partici-pate in several projects including theelucidation of growth hormone,relaxin and inhibin mechanisms ofaction. A background In physiologyor second messenger biochemistrywould be helpful. (#1920SW)Genentech, Inc. offers and excellentsalary and benefits package coupledwith the opportunity to make a sig-nificant contribution to our organiza-tion. Please send resume, Indicatingposition title and number, to HumanResources Department, Genentech,Inc., 460 Point San Bruno Boulevard,South San Francisco, CA 94080. Anequal opportunity employer.

(LEsc1=Dnhg UUniEo

Genentech, Inc.SsnsTs(ih,, Anao

POSITIONS OPEN

RESEARCH INORGANIC RADIOCHEMIST:Ph.D. and/or equivalent experience in inorganic chemis-try of actinide elements and radiochemical procedures forseparation and determination of actinides. Strong back-ground and experience in classical inorganic research(not analytical chemistry) required and in electrochemis-try desirable. Salary: $32,000 to $38,000. Only U.S.citizens apply. Send letter and form SF-171 to: XayGilbeit, Personnel Office, U.S. Geological Survey,MS 203, Box 25046, Lakewood, CO 80225. TheFederal Goernment is an Equal Opportunity Employr.

VLEStARCH SCIENTIST. Design and constructionof specialized and complex electromc and optical instru-muets for use in basic research on photosynthesis, and inbiological oceanography; including the interface of theinstruments to existing instruments, and associated soft-ware development. Forty hours, 8:30 a.m. to 5:00 p.m.$2915.67 per month. Doctorate. Major field of study-biophysics, 2 years of experience in fluorescence theoryand detection and instrumentation techniques. Job Or-der No. 0603301, D.O.T. Code 023061014. Rcsumito: NYS Job Service, 55 Medford Avenue, Patchoguc,NY 11772. Equal Opportunity Employr MIF.

SENIOR RESEARCH SCIENTIST, GLYCOPRO-TEIN BIOCHEMIST, full-time research positionavailable for scientist (Ph.D. or M.D.) with expertise in

the biosynthesis of extracellular matrices with emphasisoni basement membranes. Experience in cell biologytechniques would be valuable. The successful candidatewill jom a renal research group, with interests in renalmetabolism and biochemical alterations in diabetes. Ap-plicants must have a publication track record, grantsman-ship abilities, and be capable of independent research.Salary ($35,000 to $50,000 per year) is assured for a 2-to 3-year period and will be coitimensurate with creden-tials. Please send curriculum vitae, publications list, pastand present grant support information, and other sup-portive material to: Mr. David Shepherd,-Division ofNephrolZy and Hypertension, Clara Ford Pavilion5, HIe FPord Hospital, 2799 Wcst Grand Boule-vard, Detroit, MI 48202. Telephone: 313-876-2709.

STAFF RADIATION THERAPISTThc University ofMichigan Medical School, Depart-ment of Radiation Oncology, has an opening for aclinical radiation therapist to work in a commuunihospital in southeastern Michigan. This individual willbe responsible for consulting with and evaluating pa-tients, prescribing treatment, and supervising the admm-istration of that treatmcnt. This will be a non-tenuredposition, rank will depend on qualifications and experi-cncc. Interested persons should send curriculurtm vitae to:Allen S. Lichter, M.D., Chirman, Untiveity of

? tidXn Medical Center, Deprmnt of RadiationOncolog, 1500 East Meicai Center Drive, UH-B2C490/0010, Ann Arbor, MI 48109-0010. TheUniety ofMichban is an Equal OpportunityIAffirativeAction Employcr. PCN 15.

T-CELL CULTURISTS/IMMUNOLOGISTLAB SUPERVISOR

Massachusetts Gencral Hospital, Boston-Seeks asenior level technologist who has extensive cxperience inT-cell culture as well as immunology. You will beresponsible for coordinating all technical activities of thelaboratory. Requirements: 3 to 5 years of direct immu-nology research, plus M.S. in biology, biochemistry, orbiotechnology.

Call, or send r6sumi to:Harold Gregory

Employmcnt Service OfficeMassachusetts Gcneral Hospital

15 Fruit StreetBoston, Massachusetts 02114Telephone: 617-726-2205

We are an Equal Opportunity/Affirmaiv Action Em-ployer.

BIOLOGY: TENURE-TRACK POSMON, Sep-tember 1987. Teach general biology, microbiology, bac-teriology, and genetics. Appreciation of the Liberal Artsphilosophy is important. Interest in intcrdisciplinaryactivities, student advising, and faculty committee workis expected. Ph.D. preferred. Send curriculum vitae andthree letters of reference by 20 April 1987 to: Dr. L N.

Stauffir, Biology Departmcnt, Drnry Collegc,Springficld, MO 65802.

1710

POSITIONS OPEN

The Registry ofAIDS Pathology, American Registryof Pathology, an Equal Oppontunity Employer, invitesimmnediate applications from RESEARCH SCIEN-TISTS AND TECHNICIANS for virology and molec-ular biology section. Candidates for scientist positionmust have a Ph.D. or M.D. and appropriate researchexperience. Preference will be given to applicants withexperience in cell and virus culture, immunoassays, parti-cle isolation and purification, and molecular cloning.Depending on previous expenence, annual salary to$34,000 fror scientists and $23,000 for technicians plusfringe benefits. Submit resumr by 15 April 1987 to: Box34, SCIENCE.

CONFERENCES

INTERNATIONAL CONFERENCE ONREPRODUCTION

AND HUMAN CANCER11 to 13 May 1987

The National Cancer Institute and the NationalInstitute of Child Health and Human Develkpmentare sponsoring an International Cotifcrence on Repro-duction and Human Cancer in Bethesda, Maryland,11 to 13 May 1987, to focus on the effects of cancer andits treatment on reproduction, including possible geneticeffects.The purpose of the conference is to draw together

knowledge and research leaders from multiple disci-plines, such as medical, pediatric, and radiation oncolo-gy; obstetrics and gynecology, endocrinology, epidemi-ology, pharmacology, psychiatry, genetics, and teratolo-gy; and reproductive, mutation, and radiation biology.CME credits applied for. For additional information

telephone: Ms. Mary E. Clark at 301-589-6760.

RADIONUCLIDES IN THE FOOD CHAINA conference entitled "Radionuclides in the Food Chain"wili be held 1 to 5 November 1987 at the LazenburgConference Center near Vienna, Austria. The programis being sponsored by the International Life SciencesInstitute (ILSI) in association with the InternationalInstitute ofApplied Systems Analysis. For more informa-tion and registration materials, contact: Lii C. Merritt,ILSI, 1126 16th Street, NW, Washingon, DC20036; telephone: 202-650-0074.

COU*SES

SOCIETY FOR NEUROSCIENCESHORT COURSE:

COMPUTATIONAL NEUROSCIENCEJUNE 4 to 6, 1987

AT TtIlE UNIVERSITY OF SOUTHERNCALIFORNIA,

LOS ANGELES, CAThis course is intended for graduate students and more

advanced neuroscientists who wish to understand therelevance of cormputational neuroscience to their re-search, and to learn the techniques of computationalneuroscience. Topics and faculty: Singk neurn strucure

andfincazon: C. Koch (Cal Tech), J. Moore (Duke), J.Rosenberg (Glasgow); Percept : M. Arbib (USC), E.Schwartz (NYU), T. Sejnowti (Johns Hopkins), Mo-

tor cntrol C. Atkeson (MIT), D. Hartin (Hawaii), D.Robinson (Johns Hopkins).

Enrollnent limited to 40; registration fee $100. Low-cost accommodation is available on the USC campus;information will be provided to registrants.For information and application form: Society for

Neuroscince, 11 Dupont Circle, 'NW, Washington,DC 20036.

PROGRAM

CAREER CHANGE OPPORTUNITYThis unique program offers the candidate with a doctor-ate-level degree In science the opportunity to earn thedoctor of optometry (O.D.) degree in 2 calendar years.Employment opportunities exist in private practice, in-

dustry, education, and research. Contact: Dr. D. M.Chauncry, Ph.D.-O.D. Prgram Director, The NewEnglad College of Optometry, 424 Beacon Street,Bstoni, MA 02115; telephone: 617-266-2030, ex-tension 147.

ANNOUNCEMENTS

ANNOUNCEMENTTEACHING POSITIONS at Jordan University ofScience and Technology, Irbid, Jordan. The Facultyof Public Health and Allied Health Sciences invitesapplications for posts of professor, associate professor,and assistant professor in the specialties of: environmen-tal health, epidemiology, nutntion, virology, diagnosticendocrinology, instrumental analyses, and health admin-istration. Candidates must hold a Ph.D. degree or equiv-alent and have experience in teaching and research.Applicants should write, enclosing resurne not later than17 April 1987 to: Employee's Affairs Department,Jordan University of Science and Technology, Irbid,Jordan.

FELLOWSHIPSPOSTDOCTORAL FELLOWSHIPS (M.D. orPh.D.) for advanced training involving basic and clinicalresearch of relevance to biological psychiatry availablefrom the Mental Health Clincal Research Center forAffective Disorders at the University of Pittsburgh.$16,000 to $23,000 annually, commensurate with expe-tience. Applications for fall 1987 fellowships should bereceived before 15 April 1987 and include curriculumvitae, statement of research intercsts, and three letters ofrecommendation. Contact: Ms. Hermi Rojahn, West-ern Psychiatric Institute and Clinic, E-1213, 3811O'Hara Street, Pittsburgh, PA 15213.

POSTDOCTORAL FELLOWSHIPS FORRESEARCH IN

NEUROPLASTICITY AND REGENERATIONPositions are available after July, 1987 for interdisciplin-ary studies in neuroplasticity and regeneration. Theprogram is sponsored by the Departnents of Neurosci-ence, Neurology, Neurosurgery, and Otolaryngology atthe University of Virginia School of Medicine. Currentresearch interests ofthe participating faculty focus on theneural mechanisms involved in CNS injury and diseaseand neuromuscular disorders. Participating faculty in-dude J. Benne, E. Lothman, L. Heimer, J. A. Jane,Y. I. Kim, N. J. Lenn, W. B. Levy, 0. Steward, and G.F. Wooten. Applicants should hold either the Ph.D. orM.D. degree, and should be committed to a careerinvolving research. We are particularly interested inclinically trained individuals with a comtnitment to basicresearch. Address inquiiries to:

Oswald Steward, Ph.D.Neuroplasticity and RegenrationTii Pogram

-Department of Neuroscience, Box 230University of Virwgnia School of Medicine

Charlottesville, VA 22908The Unirmity of Vitrinia is an Affirmativc Acton/EqualOpportunity Employer.

LUPUS RESEARCH SCHOLARAWARD PROGRAM

Terri Gotthelf Lupus Research Institute invitesapplications and nominations for five scholarships avail-able 1 July 1988.The purpose of this program is to support research

training at the postdoctoral level in vanous aspects ofclinical and experimental systemic lupus ervthematosusresearch.

Candidates with a Ph.D. or M.D. degree, having U.S.citizenship or residence, are eligible to apply. A candidatemust be nominated by a scientist in whose laboratory theproposed research will be conducted.The award is for a period of 3 years, in the amount of

$90,000.The deadline for filing is 15 August 1987. Information

and specific application requirements are available uponwritten request only from:

Term Gotthelf Lupus Research InstituteAdmninistrative Office50 Washington Street

South Norwalk, CT 06854

PHARMACOLOGY AND TOXICOLOGY FEL-LOWSHIPS: Fellowships are available leading to thePh.D. degree. Stipends range from $7,000 to $10,000plus full tuition remission. Department offers a widevariety of rescarch projects. For furithr informationcontact: Dr. Leonard Waite, Department of Pharma-cooyadTo-xicology, University ofLouisville, Lou-

isv KY 40292.

SCIENCE, VOL. 235

Syva, a subsidiary of Syntex, is a lead-er in medical diagnostics develop-ing. manufacturing and marketing teststo diagnose infectious diseases and todetect and quantify clinically signifi-cant substances in patients' bodyfluids. We provide opportunities forinnovative research few biotechnologycompanies can match...in some of thefinest facilities in the country.

Currently, we have a number of op-portunities at all levels in the followingdisciplines:

.Organic Chemistry*Surface Ing

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hSi. Si x=fiS ->^,;_e', '.- DiL'Ss-9 .'. .-= ;'<A' =t-0 '9- f < ;>aS'"l -.' D ' m - z _ - t- z 0 ;2 t; D - 7 S; i;Creative senior scientists withexperience in the above disciplines areneeded for laboratory positions relatedto new assay development in both ourResearch and Development groups. Toqualify for these key openings, a PhDor equivalent is essential with relatedpost doctoral and/or industrialtraining.

In addition, we are looking forpostdoctoral fellows and BS/MS levelscientists with strong analyticalcapabilities Some positions requireindustrial experience.

Syva's excellent benefit package in-cludes generous relocation assistance.Please send your resume or CV to:Syva, Dept. DPIS, Professional Staff-ing, PO. Box 10058, Palo Alto, CA94303. An equal opportunity employer.

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