p446: usage of potentially inappropriate medications among the hospitalized elderly fallers
TRANSCRIPT
S222 Poster presentations, Friday 19 September 2014 / European Geriatric Medicine 5S1 (2014) S159–S234
would provide prevention/treatment against STDs. Majority of
FGD participants believed in TM efficacy than orthodox-medicine.
Hence, Magun could detect/prevent diseases. FGD participants
opined that TM for-instance: Ale or Erii-in; Ajidewe and Agunmu
are for erection; Ale is for ejaculation and sperm-production, Aseje
and Afaatoo enhance multiple sexual-rounds, Agbo or Ogbolo and
Tude boost sexual-performance.
Most elderly in Nigeria used TM to enhance sexual performance.
However, these products are yet to undergo clinical evaluation for
sexual medicine. There is need to support its clinical investigation
especially the claims in the improvement of sexual health.
P446
Usage of potentially inappropriate medications among the
hospitalized elderly fallers
K. Mamun
Singapore General Hospital, Singapore, Singapore
Introduction: Potentially inappropriate medications (PIMs) are
being prescribed for the elderly patients worldwide at an
alarming rate. These medications may lead to falls and subsequent
hospitalizations. A study was planned to assess the prevalence of
PIMs use in the elderly who have been hospitalized due to falls in
Singapore.
Methods: A single-centre, retrospective cohort study was
conducted at an acute care hospital in Singapore over three months
to assess the prevalence of PIMs use before a fall of community
dwelling elderly (age >65) based on 3 explicit criteria; Beers’
List 2003 & 2012, and STOPP 2008 criteria. Data extracted from
hospital electronic database for all patients with ICD-9 diagnosis of
‘hospitalizations due to falls’ and admitted during the study period
were analysed for PIMs based on above criteria.
Results: Our study included 577 patients, 73.1% of whom were
females. The mean age was 79.3 (±0.3) years, average length
of stay was 10.9 (±0.5) days and the hospitalization cost was
SGD$3011.67 (±155.1) (USD2400). At least one PIMs was prescribed
in 43.3% of our study cohort. Prevalence of PIMs were 32.9%,
41.2% and 12.1% as per Beers 2003, Beers 2012 and STOPP criteria
respectively.
Conclusions: Use of PIMs is high among the community dwelling
elderly in Singapore who were hospitalized after a fall. More
awareness among prescribers about potential side effects of
commonly prescribed medications for the elderly may help reduce
the number of falls in this elderly population.
P447
Efficacy of geriatric intervention on polypharmacy
consumption. Experience in an outpatient geriatric service
J.D. Castro-Alvirena, C. Verdejo-Bravo, P. Gil Gregorio,
A.M. Lebreault Polanco
Hospital Clınico San Carlos, Madrid, Spain
Introduction: The aim of this study was to analyze the relationship
between comorbidity and the number of drugs used among patients
treated (first visit and follow up-visits) in an outpatient clinic of a
geriatric department.
Methods: A cross-sectional, observational study was conducted in
an outpatient geriatric service during June and July 2012. Sample:
consecutively referred patients were included in two groups: First
visit, new patients (group A) and follow up (group B) by random.
Comorbidity (Charlson index), number of medications currently
taken, pharmacological groups, and demographic variables were
analysed. Data was obtained through a personal interview, and
answering a questionnaire.
Statistical analysis was done with STATA 12.
Results: Sample: 108 patients. Group A: 62 patients (57.4%),
women: 48. Mean age: 82.9, drug number (percentile 50th): 8.
Charlson index (percentile 50th): 2. Patients using more than
5 drugs: 52 (83.9%). Most commonly pharmacologic groups used:
PPI: 43 (69%), antihypertensive: 37 (60%), diuretics: 29 (47%),
Antiplatelet: 25 (40%), lipid-lowering drugs: 24 (39%).
Group B: 46 patients (42.6%), women: 34. Mean age: 84.6, drug
number percentile 50th: 6. Charlson index (percentile 50th): 2.
Patients using more than 5 drugs: 25 (54.4%). Most
commonly pharmacologic groups used: antihypertensive: 31 (67%),
PPI: 25 (54%), lipid-lowering drug: 20 (43%), Diuretics: 19 (41%),
NSAID: 17 (37%).
Conclusions: (1) Patients seen as first visit consumed significantly
more drugs in comparison with patients treated as follow up. They
didn’t demonstrate differences in comorbidity.
Table 1. Characteristics and comparison between new patients
(Group A), and follow up patients (Group B) treated in an outpatient
clinic of a geriatric department (total 108 patients)
Group A
(New
patients)
Group B
(Follow up
patients)
Number per group 62 (57.4%) 46 (42.6%)
Age (years) 82.9 84.6
Female, N (%) 48 (77.4%) 34 (73.9%)
Charlson Index, P 50th 2 2
Number of drugs being taken at home, P 50th 8 6
Patients taking more than 5 drugs 53 (83.9%) 25 (54.4%)
Figure 1. Most common pharmacologic groups used in new patients and in follow up
patients.
P448
Potentially inappropriate medications detected by explicit
criteria; are they really inappropriate?
I. Lozano-Montoya, M. Velez-Dıaz-Pallares, E. Delgado-Silveira,
B. Montero Errasquın, A.J. Cruz-Jentoft
Hospital Ramon y Cajal, Spain
Introduction: Explicit criteria to detect potentially inappropri-
ate (PI) drugs in older patients are not always followed by the
attending physician and some may be appropriate for a particular
patient. Our aim was to analyse the appropriateness of the
STOPP-START criteria in older inpatients using a multidisciplinary
comprehensive assessment as gold standard.
Methods: Patients admitted to an acute geriatric unit during 18
months were included. STOPP-START criteria were applied to pre-
admission treatments. A multidisciplinary geriatric team (including
a clinical pharmacist) assessed drug use and decided what drugs
were recommended after discharge. Two researches independently
reviewed when STOPP-START recommendations were not followed
and why.
Results: 388 patients were included (88.8±6.0 years, 68.3% female),
42 of them died in hospital (data excluded from analysis). In those
discharged alive, 284 PI prescriptions were identified (0.8/patient),
of which 247 (87.0%) were followed at discharge. In 37 (13%) cases