p446: usage of potentially inappropriate medications among the hospitalized elderly fallers

1
S222 Poster presentations, Friday 19 September 2014/European Geriatric Medicine 5S1 (2014) S159S234 would provide prevention/treatment against STDs. Majority of FGD participants believed in TM efficacy than orthodox-medicine. Hence, Magun could detect/prevent diseases. FGD participants opined that TM for-instance: Ale or Erii-in; Ajidewe and Agunmu are for erection; Ale is for ejaculation and sperm-production, Aseje and Afaatoo enhance multiple sexual-rounds, Agbo or Ogbolo and Tude boost sexual-performance. Most elderly in Nigeria used TM to enhance sexual performance. However, these products are yet to undergo clinical evaluation for sexual medicine. There is need to support its clinical investigation especially the claims in the improvement of sexual health. P446 Usage of potentially inappropriate medications among the hospitalized elderly fallers K. Mamun Singapore General Hospital, Singapore, Singapore Introduction: Potentially inappropriate medications (PIMs) are being prescribed for the elderly patients worldwide at an alarming rate. These medications may lead to falls and subsequent hospitalizations. A study was planned to assess the prevalence of PIMs use in the elderly who have been hospitalized due to falls in Singapore. Methods: A single-centre, retrospective cohort study was conducted at an acute care hospital in Singapore over three months to assess the prevalence of PIMs use before a fall of community dwelling elderly (age >65) based on 3 explicit criteria; Beers’ List 2003 & 2012, and STOPP 2008 criteria. Data extracted from hospital electronic database for all patients with ICD-9 diagnosis of ‘hospitalizations due to falls’ and admitted during the study period were analysed for PIMs based on above criteria. Results: Our study included 577 patients, 73.1% of whom were females. The mean age was 79.3 (±0.3) years, average length of stay was 10.9 (±0.5) days and the hospitalization cost was SGD$3011.67 (±155.1) (USD2400). At least one PIMs was prescribed in 43.3% of our study cohort. Prevalence of PIMs were 32.9%, 41.2% and 12.1% as per Beers 2003, Beers 2012 and STOPP criteria respectively. Conclusions: Use of PIMs is high among the community dwelling elderly in Singapore who were hospitalized after a fall. More awareness among prescribers about potential side effects of commonly prescribed medications for the elderly may help reduce the number of falls in this elderly population. P447 Efficacy of geriatric intervention on polypharmacy consumption. Experience in an outpatient geriatric service J.D. Castro-Alvirena, C. Verdejo-Bravo, P. Gil Gregorio, A.M. Lebreault Polanco Hospital Cl´ ınico San Carlos, Madrid, Spain Introduction: The aim of this study was to analyze the relationship between comorbidity and the number of drugs used among patients treated (first visit and follow up-visits) in an outpatient clinic of a geriatric department. Methods: A cross-sectional, observational study was conducted in an outpatient geriatric service during June and July 2012. Sample: consecutively referred patients were included in two groups: First visit, new patients (group A) and follow up (group B) by random. Comorbidity (Charlson index), number of medications currently taken, pharmacological groups, and demographic variables were analysed. Data was obtained through a personal interview, and answering a questionnaire. Statistical analysis was done with STATA 12. Results: Sample: 108 patients. Group A: 62 patients (57.4%), women: 48. Mean age: 82.9, drug number (percentile 50 th ): 8. Charlson index (percentile 50 th ): 2. Patients using more than 5 drugs: 52 (83.9%). Most commonly pharmacologic groups used: PPI: 43 (69%), antihypertensive: 37 (60%), diuretics: 29 (47%), Antiplatelet: 25 (40%), lipid-lowering drugs: 24 (39%). Group B: 46 patients (42.6%), women: 34. Mean age: 84.6, drug number percentile 50 th : 6. Charlson index (percentile 50 th ): 2. Patients using more than 5 drugs: 25 (54.4%). Most commonly pharmacologic groups used: antihypertensive: 31 (67%), PPI: 25 (54%), lipid-lowering drug: 20 (43%), Diuretics: 19 (41%), NSAID: 17 (37%). Conclusions: (1) Patients seen as first visit consumed significantly more drugs in comparison with patients treated as follow up. They didn’t demonstrate differences in comorbidity. Table 1. Characteristics and comparison between new patients (Group A), and follow up patients (Group B) treated in an outpatient clinic of a geriatric department (total 108 patients) Group A (New patients) Group B (Follow up patients) Number per group 62 (57.4%) 46 (42.6%) Age (years) 82.9 84.6 Female, N (%) 48 (77.4%) 34 (73.9%) Charlson Index, P 50th 2 2 Number of drugs being taken at home, P 50th 8 6 Patients taking more than 5 drugs 53 (83.9%) 25 (54.4%) Figure 1. Most common pharmacologic groups used in new patients and in follow up patients. P448 Potentially inappropriate medications detected by explicit criteria; are they really inappropriate? I. Lozano-Montoya, M. V ´ elez-D´ ıaz-Pallar ´ es, E. Delgado-Silveira, B. Montero Errasqu´ ın, A.J. Cruz-Jentoft Hospital Ram´ on y Cajal, Spain Introduction: Explicit criteria to detect potentially inappropri- ate (PI) drugs in older patients are not always followed by the attending physician and some may be appropriate for a particular patient. Our aim was to analyse the appropriateness of the STOPP-START criteria in older inpatients using a multidisciplinary comprehensive assessment as gold standard. Methods: Patients admitted to an acute geriatric unit during 18 months were included. STOPP-START criteria were applied to pre- admission treatments. A multidisciplinary geriatric team (including a clinical pharmacist) assessed drug use and decided what drugs were recommended after discharge. Two researches independently reviewed when STOPP-START recommendations were not followed and why. Results: 388 patients were included (88.8±6.0 years, 68.3% female), 42 of them died in hospital (data excluded from analysis). In those discharged alive, 284 PI prescriptions were identified (0.8/patient), of which 247 (87.0%) were followed at discharge. In 37 (13%) cases

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S222 Poster presentations, Friday 19 September 2014 / European Geriatric Medicine 5S1 (2014) S159–S234

would provide prevention/treatment against STDs. Majority of

FGD participants believed in TM efficacy than orthodox-medicine.

Hence, Magun could detect/prevent diseases. FGD participants

opined that TM for-instance: Ale or Erii-in; Ajidewe and Agunmu

are for erection; Ale is for ejaculation and sperm-production, Aseje

and Afaatoo enhance multiple sexual-rounds, Agbo or Ogbolo and

Tude boost sexual-performance.

Most elderly in Nigeria used TM to enhance sexual performance.

However, these products are yet to undergo clinical evaluation for

sexual medicine. There is need to support its clinical investigation

especially the claims in the improvement of sexual health.

P446

Usage of potentially inappropriate medications among the

hospitalized elderly fallers

K. Mamun

Singapore General Hospital, Singapore, Singapore

Introduction: Potentially inappropriate medications (PIMs) are

being prescribed for the elderly patients worldwide at an

alarming rate. These medications may lead to falls and subsequent

hospitalizations. A study was planned to assess the prevalence of

PIMs use in the elderly who have been hospitalized due to falls in

Singapore.

Methods: A single-centre, retrospective cohort study was

conducted at an acute care hospital in Singapore over three months

to assess the prevalence of PIMs use before a fall of community

dwelling elderly (age >65) based on 3 explicit criteria; Beers’

List 2003 & 2012, and STOPP 2008 criteria. Data extracted from

hospital electronic database for all patients with ICD-9 diagnosis of

‘hospitalizations due to falls’ and admitted during the study period

were analysed for PIMs based on above criteria.

Results: Our study included 577 patients, 73.1% of whom were

females. The mean age was 79.3 (±0.3) years, average length

of stay was 10.9 (±0.5) days and the hospitalization cost was

SGD$3011.67 (±155.1) (USD2400). At least one PIMs was prescribed

in 43.3% of our study cohort. Prevalence of PIMs were 32.9%,

41.2% and 12.1% as per Beers 2003, Beers 2012 and STOPP criteria

respectively.

Conclusions: Use of PIMs is high among the community dwelling

elderly in Singapore who were hospitalized after a fall. More

awareness among prescribers about potential side effects of

commonly prescribed medications for the elderly may help reduce

the number of falls in this elderly population.

P447

Efficacy of geriatric intervention on polypharmacy

consumption. Experience in an outpatient geriatric service

J.D. Castro-Alvirena, C. Verdejo-Bravo, P. Gil Gregorio,

A.M. Lebreault Polanco

Hospital Clınico San Carlos, Madrid, Spain

Introduction: The aim of this study was to analyze the relationship

between comorbidity and the number of drugs used among patients

treated (first visit and follow up-visits) in an outpatient clinic of a

geriatric department.

Methods: A cross-sectional, observational study was conducted in

an outpatient geriatric service during June and July 2012. Sample:

consecutively referred patients were included in two groups: First

visit, new patients (group A) and follow up (group B) by random.

Comorbidity (Charlson index), number of medications currently

taken, pharmacological groups, and demographic variables were

analysed. Data was obtained through a personal interview, and

answering a questionnaire.

Statistical analysis was done with STATA 12.

Results: Sample: 108 patients. Group A: 62 patients (57.4%),

women: 48. Mean age: 82.9, drug number (percentile 50th): 8.

Charlson index (percentile 50th): 2. Patients using more than

5 drugs: 52 (83.9%). Most commonly pharmacologic groups used:

PPI: 43 (69%), antihypertensive: 37 (60%), diuretics: 29 (47%),

Antiplatelet: 25 (40%), lipid-lowering drugs: 24 (39%).

Group B: 46 patients (42.6%), women: 34. Mean age: 84.6, drug

number percentile 50th: 6. Charlson index (percentile 50th): 2.

Patients using more than 5 drugs: 25 (54.4%). Most

commonly pharmacologic groups used: antihypertensive: 31 (67%),

PPI: 25 (54%), lipid-lowering drug: 20 (43%), Diuretics: 19 (41%),

NSAID: 17 (37%).

Conclusions: (1) Patients seen as first visit consumed significantly

more drugs in comparison with patients treated as follow up. They

didn’t demonstrate differences in comorbidity.

Table 1. Characteristics and comparison between new patients

(Group A), and follow up patients (Group B) treated in an outpatient

clinic of a geriatric department (total 108 patients)

Group A

(New

patients)

Group B

(Follow up

patients)

Number per group 62 (57.4%) 46 (42.6%)

Age (years) 82.9 84.6

Female, N (%) 48 (77.4%) 34 (73.9%)

Charlson Index, P 50th 2 2

Number of drugs being taken at home, P 50th 8 6

Patients taking more than 5 drugs 53 (83.9%) 25 (54.4%)

Figure 1. Most common pharmacologic groups used in new patients and in follow up

patients.

P448

Potentially inappropriate medications detected by explicit

criteria; are they really inappropriate?

I. Lozano-Montoya, M. Velez-Dıaz-Pallares, E. Delgado-Silveira,

B. Montero Errasquın, A.J. Cruz-Jentoft

Hospital Ramon y Cajal, Spain

Introduction: Explicit criteria to detect potentially inappropri-

ate (PI) drugs in older patients are not always followed by the

attending physician and some may be appropriate for a particular

patient. Our aim was to analyse the appropriateness of the

STOPP-START criteria in older inpatients using a multidisciplinary

comprehensive assessment as gold standard.

Methods: Patients admitted to an acute geriatric unit during 18

months were included. STOPP-START criteria were applied to pre-

admission treatments. A multidisciplinary geriatric team (including

a clinical pharmacist) assessed drug use and decided what drugs

were recommended after discharge. Two researches independently

reviewed when STOPP-START recommendations were not followed

and why.

Results: 388 patients were included (88.8±6.0 years, 68.3% female),

42 of them died in hospital (data excluded from analysis). In those

discharged alive, 284 PI prescriptions were identified (0.8/patient),

of which 247 (87.0%) were followed at discharge. In 37 (13%) cases