Achieving competitive advantage through genomics Genomics and related biosciences are advancing at an extraordinary pace as new discoveries are made that enable the development of innovative products and services. As a consequence, the emergence of new genomics technologies is driving productivity, product commercialisation and commercial competitiveness.

BRISBANE

SYDNEY

PERTH ADELAIDE MELBOURNE

1300 247 301HEAD OFFICE

AUSTRALIAN GENOME RESERACH FACILITY Suite 219, 55 Flemington Road

North Melbourne, VIC 3051 Phone: +61 3 9321 3701 Email: info@agrf.org.au

© Australian Genome Research Facility Ltd 2016 ABN 63 097 086 292

COMMERCIALGENOMICS> ADVANCING INDUSTRIES

> CREATING COMPETITIVE ADVANTAGE

OUR LOCATIONS

www.agrf.org.au www.agrf.org.au

Who we are With facilities in Brisbane, Sydney, Melbourne, Adelaide and Perth, AGRF is Australia’s largest genomics service provider. Along with our state-of-the-art facilities and technologies, we also offer scientific and technical expertise in consultation with users of our services.

As a key enabler of genomic innovation and development, we deliver a unique breadth of services across the entire biological spectrum to over three thousand users spanning academia, industrial and other commercial sectors.

What we do We help our customers accelerate life sciences research, solve challenges, improve diagnostics, develop new products and refine processes to increase productivity. We help bridge the gap between research and the needs of commerce. We work with clients from industries such as; medicine, healthcare, agriculture, bio-products, environment, food, water, energy and mining sectors. Our core business units consist of:

Project design and advice DNA Extraction DNA and RNA sequencing Genotyping Bioinformatics analysis.

Uncovering Insights We support the entire innovation pipeline to discover and translate new knowledge into applied outcomes. Whether it be discovery, development or a service delivery, we can develop applications for you with real world utility. Our technical expertise will enable us to consult with you in a range of areas including:

Advice on genomics approaches to address business challenges

Selecting appropriate technologies, study design, data production and its analysis

Connections with researchers to develop collaborations

Access to new technology and reliable delivery Funding assistance for pilot projects and

contributions to grant programs Planning and the execution of development projects

Custom Solutions We know every project is unique. Our genomic services can be tailored to help you stay ahead of competition in today’s fast paced environment. We help companies with the entire spectrum of services in the genomics value chain - from interpretational needs to complex research projects.

Accesible expertise We believe that the deepest connections come from ongoing collaboration and dialogue. We allocate a dedicated account manager to each industry partner to ensure continuous support.

Networks Highly networked at the national and international level with researchers, institutions, and funding agencies.

R&D with a registeredresearch agency We are a Registered Research Agency (RRA) and therefore registered as Research Service Provider (RSP). This means every dollar spent with AGRF could be eligible for a tax offset.

Commitment to quality Quality and the provision of quality data is an integral part of our everyday routine; our culture and why we take pride in what we do. AGRF has established large-scale logistical and technical systems that ensure quality data and outcomes for projects that are delivered in a timely and cost-effective manner. To ensure our regulated services generate and deliver the highest level of quality to our users, we participate in national and international benchmarking programs (e.g. American College of Pathologists).

Our accreditations We have a number of services accredited by the National Association of Testing Authorities, Australia (NATA) in the field of Biological Testing and we operate in compliance with the international standard ISO/IEC 17025:2005. We are also certified by a number of our technology suppliers as Certified Service Providers.

We welcome user audits We see our clients as valued partners and in order to maintain transparency, operational confidence and service excellence we are routinely audited by our clients including; manufacturers, pharmaceutical groups, clinical genomics groups, government bodies and clinical service providers to comply with their quality management system (QMS) and to ensure all of our services and procedures meet their rigorous regulatory requirements.

Case Examples DIAGNOSTICS - organisations outsource cytogenetic microarray investigations on developmental delay and miscarriage testing that are rebatable through Medicare. AGRF processes supplied genomic DNA samples with NATA accredited processes and provides raw data for interpretation by the client’s in-house cytogenetic experts. TEST DESIGN AND DELIVERY – with a commercial supplier of forensics testing kits, AGRF developed a DNA detection methodology to apply in their supply chain to meet with a new Australian testing standard. AGRF continues to routinely provide this testing to the client for batch verification. SERVICE PRODUCT - A lifestyle genomics company uses AGRF’s microbial services for gut microbiome analysis in conjunction with healthcare practitioners. Stool samples are provided, and the bacteria in the stool are profiled using DNA sequencing which is analysed to provide composition reports based on the scientific literature.

OUR FACILITYWith five laboratories distributed nationally and state-of-the-art genomics equipment we offer innovative capabilities, technology accessibility and comprehensive support.

Access to five PC2 and PC1 laboratories ISO/IEC 17025:2005 accredited protocols 48 laboratory technicians providing comprehensive

support and experience

Over $20 million invested in current genomics platforms

Early access to new technologies Fully integrated LIMS system Equipped with IT and data management systems for

largescale projects Fully integrated LIMS connects projects and

advanced bioinformatics.

ABOUT NATA

Achieving accreditation from NATA means our standards and competences have met those of the international standard ISO/IEC 17025 and formally recognise continuous high quality service and technical competence provided to our clients.

NATA is one of the largest laboratory accreditation bodies in the world and is responsible for the accreditation of laboratories, inspection bodies,

calibration services, producers of certified reference materials and proficiency testing scheme providers throughout Australia.

NATA ensures that member facilities comply with standards and provide reliable testing, calibration, measurement, and inspection data to government, industry, and other markets.

ABOUT US WHY WORK WITH US

BIOMEDICAL

PHARMA

AGRICULTURE

ENVIRONMENT

FORENSICS

GENETIC TESTING

PATHOLOGY

FOOD

DISCOVERY Genomics techniques are used to discover biological markers that can lead to new information, such as therapeutic or diagnostic products.

DEVELOPMENTWe help design, develop, validate and implement novel assays for a broad range of applications relevant to areas such as pharmaceuticals, pathology, agriculture and horticulture, genetic testing and forensics.

DELIVERYA reliable, commercially savvy provider of predesigned assays in business to business contracts to support broader client functions.

From discovery to service delivery, powered with genomics insight.