open source pharma workshop - what is open source pharma?

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“open source pharma” legal, technical, organizational considerations

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Presentation on open source pharmaceutical models from the OSPharma workshop in Bellagio, July 2014.

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Page 1: Open source pharma workshop - what is open source pharma?

“open source pharma” !

legal, technical, organizational considerations

Page 2: Open source pharma workshop - what is open source pharma?

it’s inaccurate to call open source pharma open source…

but i’m ok with that.

Page 3: Open source pharma workshop - what is open source pharma?

it’s inaccurate to call open source pharma open source…

but i’m ok with that.

Page 4: Open source pharma workshop - what is open source pharma?

“open source”

Page 5: Open source pharma workshop - what is open source pharma?

open source is not: a magic spell, a verb, or a guarantee.

Page 6: Open source pharma workshop - what is open source pharma?

commons-based peer production

Page 7: Open source pharma workshop - what is open source pharma?

modular granular

integratable

Page 8: Open source pharma workshop - what is open source pharma?

regularly outperforms both the large “firm” and the “unorganized

market” in creating complex, stable software or cultural artifacts.

Page 9: Open source pharma workshop - what is open source pharma?

regularly fails at:

Page 10: Open source pharma workshop - what is open source pharma?
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inside the firm, modular, granular, integratable.

Page 12: Open source pharma workshop - what is open source pharma?

outside the firm, lots of efforts within the chevrons.

Page 13: Open source pharma workshop - what is open source pharma?

some CBPP, some PP, some fee for service, some “artisan” open.

Page 14: Open source pharma workshop - what is open source pharma?

outside the firm, yet to demonstrate ability to achieve

modular, granular, integratable to create a submittable drug.

Page 15: Open source pharma workshop - what is open source pharma?

the resources required to make open source knowledge need

not be themselves open source…but they must be

commodities.

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knowledge products that come off these platforms are

themselves rarely modular, granular, integratable.

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there is a serious potential conflict between individual

privacy risks and open access to the data.

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(from health records, .25% probability of re-identification

upon directed attack)

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we don’t have a firm to coordinate this process.

Page 27: Open source pharma workshop - what is open source pharma?

which means we are the ones who must build the first version of the modern pharmaceutical system.

Page 28: Open source pharma workshop - what is open source pharma?

which means we must commit to: !

standard formats on our data. investment in annotation.

modularity in our tools. granularity in our tasks.

integration with each other.

Page 29: Open source pharma workshop - what is open source pharma?