No, they wont infect you

Download No, they wont infect you

Post on 19-Jan-2016




0 download


No, they wont infect you. Celline Kim----------------------Final Presentation-----------------------------------2009. - PowerPoint PPT Presentation


  • No, they wont infect youCelline Kim----------------------Final Presentation-----------------------------------2009



  • Influenza A virus


  •, 03

  • Novosad, 2002Acta Medica Journal

  • Idea Summation

    Influenza stimulates 4-NP suppresses

    Gene of interest: Sialic Acid Binding Ig-like lectin 12

    U937 (ATCC) 4-NP + Estrogen

  • Novosad J, Fiala Z, Borska L, Krejsek J. Immunosuppressive effect of polycyclic aromatic hydrocarbons by induction of apoptosis of pre-B lymphocytes of bone marrow. Acta Medica (Hradec Kralove). 2002;45(4):123128.

    Eva C. Bonefeld-Jrgensen,1 Manhai Long,1 Marlene V. Hofmeister,1 and Anne Marie Vinggaard. Endocrine-Disrupting Potential of Bisphenol A, Bisphenol A Dimethacrylate, 4-n-Nonylphenol, and 4-n-Octylphenol in Vitro: New Data and a Brief Review. Environ Health Perspect. 2007 December; 115(S-1): 6976.

    Bonefeld-Jorgensen EC, Ayotte P. AMAP Assessment 2002: Human Health in the Arctic. Oslo, Norway: Arctic Monitoring and Assessment Programme; 2003. Toxicological properties of POPs and related health effects of concern for the Arctic populations; pp. 5774.

    Bjornstrom L, Sjoberg M. Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. Mol Endocrinol. 2005;19(4):833842.

    Fries, E., Puttmann, W. The dissipation, distribution and fate of a branched C14-nonylphenol isomer in lake water/sediment systems.

    Hoponick, Jenny. Nonylphenol Ethoxylates. Sierra Club. 2005.

    Jung, Mi Young, Kim, Tae Sung. Differential modulation of regulatory T cell activities by nonylphenol, octylphenol, and diethylstilbestrol. The Journal of Immunology. 2009. 182:47.3. The American Association of Immunologists.

    Yao, Genhong, and Hou, Yayi. Nonylphenol induces thymocyte apoptosis through Fas/FasL pathway by mimicking estrogen in vivo. Environmental Toxicology and Pharmacology. May 2004. Volume 17, Issue 1. P. 19-27.

    Moran, TM, Isobe, H, Fernandez-Sesma, A, Schulman, JL. Interleukin-4 causes delayed virus clearance in influenza virus-infected mice. Department of Microbiology. Journal of Virology. August 1996, 5230-5235. Vol 70, No.8.

    Ludwig, S, Ehrhardt, C, Neumeier, E.R., Kracht, M., Rapp, U.R., Pleschka, S. Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway. Journal of Biology and Chemistry. April 2001. Vol. 276, Issue 14, 10990-10998.



View more >