niper 2010 q paper

2
NIPER -2010 11 july 2010 1-carbomer composition 2-rifampicin solublity in bbb 3-mao of erythromy cin 4 which drug is safe in renal failure- cloxacillin,streptomycin,cephalorin 5 defination- antibody titer 6 protein precipitation used for a-for estimation of protein from urine b-'' '' '' '' '' serum c- ' '' '' '' '' blood 7- listerine(brand name for a mouth wash) manufac by a johnson and johnson b procter ang gamble 7- i-pill is marketed by-------- 8-in india commodity bussiness sontrolled by a-SEBI b-frm c- d- 9- ist ayush gram located in uttrakhand ,himachal pradesh 10-mao of flouroquinolone 11 teratogenicity of corticosterods ,thalidomide 12-maths question about identification of trapezoid 13-freeze thaw test used for suspension a- for degradation b-crystaliz ation of suspension(i think it is r ight) 14.chem const of atopa belladona many ques are frm cognosy abt biological source chem constituent..n o ques from biosynthesis 14 -how many doublets contains paracetamol? 15-mull used in a-ft ir b-raman 16.mclaffre y ion m/z values 17homoannolar and heteroannular dienes 18-calculation of lambda max using wood word fisher rule of uv 19-carbocation stablity 20.bond energies a- C-H >C- C>C-OH >C -CL b-C-CL>C-H >C-C>C-OH c- d- 21-which is a nucleophile a NH2 b-cooh c - d- 22-enzyme used for cutting dna in biotecnology 23-defination of specific 24-specific activity of enzyme 25-plasmid of bacteria-char acters 26- a lot of cology ques has come about 60 in no. drug used in glycemic control in diabetes a pioglitazone b- 27-insulin contraindicated with a-propranol b- c - d- 28-in hypertension whi ch drug give immediate relief? a- nitroprusside b-prazocin 29-interaction ofsildenafil and nitroglycerin e 30 types of bond in antigen and antibody interaction a-hydrophobic b- vander waal c-covalent bond 31-heparin action blocked byquinidine 32-drugs that stimulate CTZ zone – morphine, apomorphine, serotonin 33-antidote of cyanide 34-which process no t blocked by cyanide hmp pathway.kre bs cycle, glycolysis 35-which process ds not occur in mitochondria kreb cycle lipid biosynthesis 36-cholestrol on dehydrogenation yields --- 37-wittg reaction 38-Wolf kishner reaction 39-clemmenson reaction 40-friedal craft acylation 41-mobile phase used in reverse phase chromatography 42-Stomata in senna? 43-Borntrager test is used for? 44-FDA approved drug for Osteoporosis in2010? Ans-DENOSUMAB 45-FDA approved drug for Gout IN 2OO9? FEBUSTAT 46-Chief constituent of Dill? 47-Ribosomes are synthesized in? 48-What happens in inetrphase? 49-Cis and trans are ?(Distereomer s/Enantiomers) ? 50-Adrenergic blockers are also called as? Sympatholytics Parasympathomimeics sympathommimetics 51-Cipla has recently sold iits i-pill to which company? 52-Nobleprize winner for medicine in 2009? 53-COMFA is used for? a-3d qsar b-docking

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Page 1: NIPER 2010 Q paper

8/7/2019 NIPER 2010 Q paper

http://slidepdf.com/reader/full/niper-2010-q-paper 1/2

NIPER -2010 11 july 20101-carbomer composition2-rifampicin solublity in bbb

3-mao of erythromycin

4 which drug is safe in renal failure-

cloxacillin,streptomycin,cephalorin

5 defination- antibody titer 

6 protein precipitation used for a-for estimation of protein from urine

b-'' '' '' '' '' serumc- ' '' '' '' '' blood

7- listerine(brand name for a mouth wash) manufac by

a johnson and johnson

b procter ang gamble

7- i-pill is marketed by--------

8-in india commodity bussiness sontrolled by

a-SEBI

b-frmc-

d-

9- ist ayush gram located inuttrakhand ,himachal pradesh

10-mao of flouroquinolone

11 teratogenicity of corticosterods ,thalidomide

12-maths question about identification of trapezoid

13-freeze thaw test used for suspension

a- for degradation

b-crystalization of suspension(i think it is right)14.chem const of atopa belladona

many ques are frm cognosy abt biological source chem

constituent..no ques from biosynthesis

14 -how many doublets contains paracetamol?

15-mull used in a-ft ir b-raman

16.mclaffrey ion m/z values17homoannolar and heteroannular dienes

18-calculation of lambda max using wood word fisher rule of uv

19-carbocation stablity

20.bond energies a- C-H >C-C>C-OH >C-CL

b-C-CL>C-H >C-C>C-OH

c-

d-

21-which is a nucleophile

a NH2 b-cooh c - d-

22-enzyme used for cutting dna in biotecnology23-defination of specific

24-specific activity of enzyme

25-plasmid of bacteria-characters26- a lot of cology ques has come about 60 in no.

drug used in glycemic control in diabetes

a pioglitazone

b-

27-insulin contraindicated with

a-propranol b- c - d-28-in hypertension which drug give immediate relief?

a- nitroprusside b-prazocin29-interaction ofsildenafil and nitroglycerine

30 types of bond in antigen and antibody interaction

a-hydrophobic b- vander waal c-covalent bond

31-heparin action blocked byquinidine

32-drugs that stimulate CTZ zone – 

morphine,

apomorphine,

serotonin33-antidote of cyanide

34-which process not blocked by cyanide hmp

pathway.krebs cycle, glycolysis35-which process ds not occur in mitochondria

kreb cycle

lipid biosynthesis

36-cholestrol on dehydrogenation yields ---

37-wittg reaction

38-Wolf kishner reaction

39-clemmenson reaction40-friedal craft acylation

41-mobile phase used in reverse phase chromatography

42-Stomata in senna?

43-Borntrager test is used for?

44-FDA approved drug for Osteoporosis in2010?Ans-DENOSUMAB

45-FDA approved drug for Gout IN 2OO9?

FEBUSTAT

46-Chief constituent of Dill?

47-Ribosomes are synthesized in?

48-What happens in inetrphase?

49-Cis and trans are ?(Distereomers/Enantiomers)?

50-Adrenergic blockers are also called as?

SympatholyticsParasympathomimeics

sympathommimetics51-Cipla has recently sold iits i-pill to which company?

52-Nobleprize winner for medicine in 2009?

53-COMFA is used for?

a-3d qsar 

b-docking

Page 2: NIPER 2010 Q paper

8/7/2019 NIPER 2010 Q paper

http://slidepdf.com/reader/full/niper-2010-q-paper 2/2

54-SWs for Docking?

a-gold

b-glide

c-

d-all of above

55-Which detector in HPLC is most temprature sensative?56-Epigenetic DNA?

57-Scientific name of clove?

58-NF kappa is used in?

59-What are Paratopes?

60-Acid fast stains which part of mycobacterias?

61-Histones are present?

a-Eukaroyotes

b-Prokaryotesc-both

62-Nilkeni's UIC is now called as?

Pankh

AADHAR 

63-Orthostatic hypertension is a side effect of?

Methyldopa

reserpine64-Chloramphenicol is used as?antibiotic

65-indication for reserpine?

Ans-hypertension

66-sennosides present in?

67-Chief constituent of Dill?

carvone

68-dsc in anal

69- which of the line abt disintegration test is right?

A-it is not for delayed release dosage form

b-if in monograph of capsule DT is not mentioned, it is not donec-both are wrong

70- for tab below 300 mg weight variation shld bea-7.5%

b-10%

c-5%

71-detector used in hplc?

73-which of the following is a mucoadhesive?

74-Cipla has recently sold iits i-pill to which company?75-the lag phase in growth of bacteria can be prevented by?

a-replacing with new media

b-replacing with alive bacteria

76-paracetamol most severe sideffect?

Ans-nephrotoxicity

78- water immiscible non polar solvent?A-Isopropyl myristitateb-PEG

 

79-PEG coating done on lipsome

a- to obtain delayed release

80- in myasthenia gravis the receptor damaged by autoimmunue

process are?

81- name the propellant 152

82-IND stand for?

83-drug used for schizophrenia?

85-the base peak has?

a-low intensity

b-highest intensity

86-the effect of conjugation on IR absorbtion?

87-scientist name for discovery of quartlet stereochemistry incarbon?

88-structure of d-valine

89-essential fatty acids

90-epimers definition

91-anomers

92-diasteriomers and enantiomers definition

93- sn2 reaction

94-the effect of plant forskolin is due toAns stimulation of adenyl cyclase

95-aflatoxin presenting

a-fungi

b-algae

96-trypsin obtained from

a-pig stomach

b-ox stomach

97-for taste masking of bitter orals which of following used

a-citrus fruits

b-liquorice

98-the sulfasalazine consist of 

A-PAS + SULPHAPYRIDINE

B-PAS +SULPHASALAZINE

99-H.PYROLI cause

Ans ulcers

100- which of the following is a motile bacteria

a-shegalab-lactobacilus

101-the capsules are washed with

a-acetone

B

C

d

102-recinoleic acid present inAns nutmeg

103-stereoisomerism of cinnamic acid

104-tocopherol an antioxidant act as a --------

Ans-reducing agent

105 general method for sterilization of glass is-

a-autoclavinb-gamma radiationc-dry heat method

106-which of the following can’t be autoclaved-

a-polypropylene

b-teflon

c-nylon

no ques from English and bank