nimh/dar research priorities and funding opportunities

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NIMH/DAR Research Priorities and Funding Opportunities Christopher Gordon, Ph.D. Branch Chief, NIMH Division of AIDS Research Johns Hopkins CFAR November 5, 2014

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Christopher Gordon, Ph.D. Branch Chief, NIMH Division of AIDS Research

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Page 1: NIMH/DAR Research Priorities and Funding Opportunities

NIMH/DARResearch Priorities and Funding Opportunities

Christopher Gordon, Ph.D.

Branch Chief,

NIMH Division of AIDS Research

Johns Hopkins CFAR

November 5, 2014

Page 2: NIMH/DAR Research Priorities and Funding Opportunities

Toward Combination HIV Prevention

Coates 2008 Lancet

Page 3: NIMH/DAR Research Priorities and Funding Opportunities

Selected NIMH HIV Research Priorities

Targets Funding Opps

Adherence to ART and PrEP PA-14-126

Steps in HIV care continuum PA-14-132

Approaches

Social determinants and structural interventions PA-14-133

Addressing stigma and health PA-13-248

Mental health and syndemic factors Stay tuned

Basic behavioral and social science PA-14-127

Implementation science PA-14-131

Populations

Key populations evidencing disparities Throughout

Page 4: NIMH/DAR Research Priorities and Funding Opportunities

Adherence to ART and PrEPNIMH PA-14-126

Improve adherence monitoring

Novel approaches/technologies for:-- Timely detection of non-adherence -- Triaging those in need to intervention-- Empower patients via real-time feedback loops

Test novel interventions to improve PrEP and ART outcomes

-- Technology-assisted approaches-- Targeting syndemic factors (e.g. depression)-- Structural/social determinants approaches

(e.g. microeconomic, food security, anti-stigma)

WisepillHaberer 2010 AIDS Behav

CBT-ADSafren 2009 Health Psy

NIMH Contact:Dr. Michael Stirratt

Page 5: NIMH/DAR Research Priorities and Funding Opportunities

Improving the HIV Care ContinuumNIMH PA-14-130

Study pathways through the care continuum

-- longitudinal studies-- disparities populations

Identify determinants and evaluate approaches to strengthen…

-- HIV testing (inc. home-testing)-- Linkage to care-- Retention in care

Requires research teams to be academic & DoH partnerships.

NIMH Contact:Dr. Christopher Gordon

Wel-Tel Retain InterventionVan der Kop + Lester 2013 BMJ Open

Determinants of Care EngagementMugavero 2011 CID

Page 6: NIMH/DAR Research Priorities and Funding Opportunities

Social Determinants/Structural Interventions NIMH PA-14-133

Target areas include… -- Stigma and discrimination -- Social violence-- Economic factors -- Legal factors

Emphasis on… -- mechanisms by which social determinants shape prevention and treatment

-- informing structural interventions to ameliorate these processes and improve outcomes

Sociocultural

Community

Interpersonal

Individual

NIMH Contact:Dr. Cynthia Grossman

Socio-Ecologic PerspectivesFood Insecurity / Income Generation

Weiser 2011 Am J Clin NutrTsai 2013 PLoS Med

Page 7: NIMH/DAR Research Priorities and Funding Opportunities

Implementation Science and Translational Research NIMH PA-14-129/131

Key Highlights

Program Officer: Christopher Gordon

Mechanism(s): R01 (131) R21 (129)

Objectives and Scope

Maximize the public health impact of

available interventions

- Deliver interventions efficiently and effectively- Transfer from one setting/population others- Better-informed public health decisions

Projects include, but are not limited to:

- Dissemination Research- Research Syntheses- Cost-effectiveness- Health Systems- Comparative Effectiveness- Policy Analysis

Page 8: NIMH/DAR Research Priorities and Funding Opportunities

NIMH Division of AIDS Research –

Contact Information

Susannah Allison, Ph.D. [email protected]

Pim Brouwers Ph.D. [email protected]

Deborah Colosi, Ph.D. [email protected]

Rebecca DelCarmen-Wiggins, Ph.D. [email protected]

Christopher Gordon, Ph.D. [email protected]

Cynthia Grossman, Ph.D. [email protected]

Jeymohan Joseph, Ph.D. [email protected]

Willo Pequegnat, Ph.D. [email protected]

Dianne Rausch, Ph.D. [email protected]

Michael Stirratt, Ph.D. [email protected]

David Stoff, Ph.D. [email protected]

5601 Fishers Lane

Rockville, MD 20852

THANKS!