Upload File

news from singapore: serious skin reactions

1
Reactions 1015 - 21 Aug 2004 ■ In the latest Adverse Drug Reaction News from Singapore, serious drug-induced skin reactions are discussed. Overall, dermatological adverse drug reactions accounted for 46% of all adverse reactions reported to Singapore’s Health Sciences Authority in 2003, although most were nonserious reactions, such as urticaria, erythema and rashes. However, between January 1997 and May 2004, there were a significant number of serious reactions, with 35 reports of toxic epidermal necrolysis (TEN) and 111 of Stevens- Johnson syndrome (SJS). Patients involved were aged 1–89 years, and most were females (n = 79). The top five drugs suspected of causing TEN and SJS were carbamazepine (n = 24), cotrimoxazole [trimethoprim/ sulfamethoxazole; 21], phenytoin (14), amoxicillin (12) and allopurinol (11). Serious drug-induced skin reactions. Adverse Drug Reaction News 6: 1 & 5, No. 2, Jul 2004 800967278 1 Reactions 21 Aug 2004 No. 1015 0114-9954/10/1015-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

Upload: vuonghanh

Post on 17-Mar-2017

214 views

Category:

Documents


2 download

Report

TRANSCRIPT

Page 1: News from Singapore: serious skin reactions

Reactions 1015 - 21 Aug 2004

■ In the latest Adverse Drug Reaction News fromSingapore, serious drug-induced skin reactions arediscussed. Overall, dermatological adverse drugreactions accounted for 46% of all adverse reactionsreported to Singapore’s Health Sciences Authority in2003, although most were nonserious reactions, suchas urticaria, erythema and rashes. However, betweenJanuary 1997 and May 2004, there were a significantnumber of serious reactions, with 35 reports of toxicepidermal necrolysis (TEN) and 111 of Stevens-Johnson syndrome (SJS). Patients involved were aged1–89 years, and most were females (n = 79). The topfive drugs suspected of causing TEN and SJS werecarbamazepine (n = 24), cotrimoxazole [trimethoprim/sulfamethoxazole; 21], phenytoin (14), amoxicillin (12)and allopurinol (11).Serious drug-induced skin reactions. Adverse Drug Reaction News 6: 1 &5, No. 2, Jul 2004 800967278

1

Reactions 21 Aug 2004 No. 10150114-9954/10/1015-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

Mandatory reporting of serious adverse drug reactions and ... · can cause serious adverse drug reactions (ADRs) and medical device incidents (MDIs), and Canadians can be hospitalized

Serious Cardiovascular Reactions: Sudden death …Stimulants used to treat ADHD are associated with peripheral vasculopathy, including Raynaud’s phenomenon. Careful observation for

zdravlje.gov.hr razni/SARE... · REPORT TEMPLATE : Serious Adverse Reaction(s) and Event(s) Annual notification for Serious Adverse Reactions Number Ad Description/Comments SAR te

Getting Started on Tresiba FlexTouch - NovoMedLink...Common side effects may include reactions at the injection site, itching, rash, serious allergic reactions (whole body reactions),

HIGHLIGHTS OF PRESCRIBING INFORMATION Major hemorrhagic ... · Perform ophthalmologic evaluation for any visual disturbances. (5.5, 2.7) Serious Febrile Reactions: Incidence and severity

Guidance Document For Reporting Serious Adverse Reactions in

Mandatory Reporting of Serious Adverse Drug Reactions and

UNIT KAJIAN DAN MAKLUMAT DRUG JABATAN FARMASI … · 2. Global Rph : Warning labels due to serious adverse skin reaction Due to serious adverse skin reactions National Pharmaceuti-cal

2019 LUMASON ULTRASOUND CONTRAST AGENT …...Serious cardiopulmonary reactions, including fatalities, have occurred uncommonly during or following the injection of ultrasound contrast

HIGHLIGHTS OF PRESCRIBING INFORMATION Serious ... · 5.3 Hypersensitivity Reactions Anaphylaxis and other serious hypersensitivity reactions can occur during treatment and upon re-initiation

Going the Distance – Towards 2010 - Sport Singapore...Here at Singapore Sports Council (SSC), we’re serious about sports and are in this game for the long haul. As such, Going

Toward Mandatory Reporting of Serious Adverse Drug ......Toward Mandatory Reporting of Serious Adverse Drug Reactions and Medical Device Incidents by Health Care Institutions . A Consultation

Adverse Events/Adverse Reactions/Serious Adverse … · Adverse Events/Adverse Reactions/Serious Adverse Reactions/ Serious Adverse Events and Suspected Unexpected Adverse ... ADR

Mandatory reporting of serious adverse drug reactions and ... · 57 5.3 In order for a serious ADR or MDI to be reported, does causality between the therapeutic product and an 58

HIGHLIGHTS OF PRESCRIBING INFORMATION - Food … · 2012-08-15 · adverse reactions, including serious adverse reactions, have been HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights

Additional File 1 Serious adverse drug reactions at two children’s …10.1186... · 2020-01-04 · 1 . Additional File 1 . Serious adverse drug reactions at two children’s hospitals

WARNING: HYPERSENSITIVITY REACTIONS, AND TRIUMEQ€¦ · Hypersensitivity Reactions • Serious and sometimes fatal hypersensitivity reactions have occurred with abacavir -containing

Metabolic acidosis: baseline and periodic …...5.6 Cognitive/Neuropsychiatric Adverse Reactions 5.7 Fetal Toxicity 5.8 Withdrawal of Antiepileptic Drugs 5.9 Serious Skin Reactions

Singapore serious games and social connect 2012

Adverse Reactions Drugs* - europepmc.orgeuropepmc.org/articles/pmc1846898/pdf/brmedj02601-0027.pdf · majority of adverse reactions are less serious than this, ... impurities which

Blood Transfusion Reactions Haemovigilance Serious Hazards of Transfusion ( SHOT )

Long-term safety and efficacy of sarilumab plus methotrexate ...serious adverse events (SAEs), serious infections, malig-nancies, MACE, injection-site reactions, ANC

Mandatory Reporting of Serious Adverse Drug Reactions and ... · Result of the serious adverse drug reaction on the patient’s health. Draft for Pilot Test Only Required Data Elements

Serious Cardiovascular Reactions: Sudden death has …dyanavelxr.com/pdfs/pi.pdfFULL PRESCRIBING INFORMATION: CONTENTS* WARNING: ABUSE AND DEPENDENCE CNS stimulants, including DYANAVEL

WARNING: PROGRESSIVE MULTIFOCAL … USPI - March 2018... · 5.2 Anaphylaxis and Infusion Reactions 5.3 Hematologic Toxicities 5.4 Serious Infections and Opportunistic Infections 5.5

Intermediate Lesson Plan · 3) Allergic reactions can be much more serious than environmental allergies/sneezing. 4) The immune system is responsible for allergic reactions. 5) People

ADVERSE REACTIONS RECENT MAJOR CHANGES DRUG …• Known hypersensitivity (e.g., anaphylactic reactions and serious skin reactions) to diclofenac or any components of the drug product

Hemolytic Transfusion Reactions · molytic transfusion reactions account for 4.3% of all transfusion reactions and 16% of all serious reactions.17,18 Pathophysiological and Clinical

ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS · General allergic reactions, including pruritus, as well as rare and sometimes serious allergic reactions such as hypersensitivity, nummular

livrepository.liverpool.ac.uklivrepository.liverpool.ac.uk/3004887/1/Post_review_PandT... · Web viewAdverse drug reactions affecting the gastrointestinal (GI) tract are a serious

WARNING: HYPERSENSITIVITY REACTIONS, AND ... · Hypersensitivity Reactions • Serious and sometimes fatal hypersensitivity reactions have occurred with abacavir -containing products

WARNING: SERIOUS ADVERSE REACTIONS INCLUDING …€¦ · TENDINITIS, TENDON RUPTURE, PERIPHERAL NEUROPATHY, CENTRAL NERVOUS SYSTEM EFFECTS AND EXACERBATION OF MYASTHENIA GRAVIS 1

Serious adverse reactions associated with ivermectin : a

Diffuse Large B-cell Lymphoma IAM KYMRIAH · • Allergic Reactions: Serious allergic reactions, including anaphylaxis, which is a life-threatening allergic reaction, may occur after

SINGAPORE DENTAL COUNCIL - MOH · Council as the guardian of professional ethics and regulatory body of the profession. It is the view of the Singapore Dental Council that serious