neuroanatomy - overview

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Neuroanatomy - overview Lennart Brodin

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Page 1: Neuroanatomy - overview

Neuroanatomy - overview

Lennart Brodin

Page 2: Neuroanatomy - overview

brain

spinal cord

cranial nerves

spinal nerves

Page 3: Neuroanatomy - overview

The components of the CNS

Telencephalon

Diencephalon

Brainstem

Cerebellum

Spinal cord

Page 4: Neuroanatomy - overview

Telencephalon

Cerebellum

Cerebral Cortex

Brainstem

Page 5: Neuroanatomy - overview

Telencephalon:

Hemispheres

Cerebral Cortex

Page 6: Neuroanatomy - overview

Cerebellum

Telencephalon

Brainstem

Spinal cord

Page 7: Neuroanatomy - overview

Sectioning the brain - nomenclature

Page 8: Neuroanatomy - overview

Coronal section

Grey matter: cell bodies

of neurons White matter: nerve tracts,

Myelin gives the white color

Page 9: Neuroanatomy - overview

Thalamus

Spinal cord

Cerebellum Hypothalamus

Die

nce

ph

alo

n

Telencephalon

Brainstem

Sagittal section

Corpus callosum:

Connects the hemi-

spheres

Page 10: Neuroanatomy - overview

Telencephalon

Thalamus

Cerebellum Hjärnstammen

Ryggmärgen

Hypothalamus

From CNS Visual Perspectives: www.3d-brain.ki.se

© Anna Josephsson

Die

nce

ph

alo

n

Page 11: Neuroanatomy - overview

Sulcus Gyrus

The Cerebral Cortex

Grey matter

White matter

Page 12: Neuroanatomy - overview

Gyrus precentralis:

Motor functions

Gyrus postcentralis:

Sensory functions

Sulcus centralis

Page 13: Neuroanatomy - overview

moto

r

sensory

vision

Primary areas

hearing

Association areas

The Cerebral Cortex – Division into Functional Areas

Page 14: Neuroanatomy - overview

Temporal lobe

Occipital lobe

Sulcus centralis

The Cerebral Cortex – Division into Lobes

Frontal lobe

Parietal lobe

Page 15: Neuroanatomy - overview

Frontal lobe

Occipital lobe

Temporal lobe

Parietal lobe

The Cerebral Cortex – Division into Lobes

Page 16: Neuroanatomy - overview

Tinninglob

Hjässlob

Nacklob

Localization of functions to lobes

Page 17: Neuroanatomy - overview

The Frontal lobe

1848: The famous case of the

railway worker Phineas Gage

gave the first insigths into the

functions of the frontal lobe

Page 18: Neuroanatomy - overview

The Frontal lobe

Page 19: Neuroanatomy - overview

Personality

Motivation

Planning

Decision-making

Social skills

The Frontal lobe

Page 20: Neuroanatomy - overview

Temporallob The temporal lobe recognition

Page 21: Neuroanatomy - overview

Activation of the temporal lobe during

recognition of a known face

fMRI signal indicates

increased activity

Page 22: Neuroanatomy - overview

Temporallob

The parietal lobe

attention

Page 23: Neuroanatomy - overview

Damage of the right parietal lobe

Page 24: Neuroanatomy - overview

Damage of the right parietal lobe

Page 25: Neuroanatomy - overview

Temporallob

The parietal lobe

attention

The posterior

temporal lobe

Recent data: The temporal lobe is also involved

Page 26: Neuroanatomy - overview

Temporallob

The occipital lobe

Receives and

processes

visual information

Page 27: Neuroanatomy - overview

Language: specific regions in the

frontal and temporal lobes

Page 28: Neuroanatomy - overview

Wernickes area: language perception

Damage results in sensory aphasia

Broca´s area: language expression

Damage results in motor aphasia

Language: specific regions in the

frontal and temporal lobes

Page 29: Neuroanatomy - overview

Nucleus caudatus

Putamen

Globus pallidus

Motor control

Cognition

Emotions

Telencephalon:

The basal ganglia

Striatum

Subcortikal nuclei

Page 30: Neuroanatomy - overview

Nucleus caudatus

Putamen

The Basal Ganglia

Page 31: Neuroanatomy - overview

Putamen

Nucleus

caudatus

The Basal Ganglia coronal section

Page 32: Neuroanatomy - overview

putamen

globus

pallidus

nucleus

caudatus

The Basal Ganglia coronal section

Page 33: Neuroanatomy - overview

The Basal Ganglia coronal section

Page 34: Neuroanatomy - overview

Nucleus

caudatus

Putamen

Globus

pallidus

The Basal Ganglia horisontal section

Page 35: Neuroanatomy - overview

Thalamus

Diencephalon horisontal section

Page 36: Neuroanatomy - overview

Nucleus caudatus

Putamen

Diencephalon

Thalamus

Page 37: Neuroanatomy - overview

Diencephalon

Thalamus

Hypothalamus

Diencephalon coronalsnitt

Page 38: Neuroanatomy - overview

Thalamus

From CNS Visual Perspectives: www.3d-brain.ki.se

© Anna Josephsson

Hypothalamus

Page 39: Neuroanatomy - overview

the brains “switch board”:

relays sensory input to the

cerebral cortex

Diencephalon

Thalamus:

Page 40: Neuroanatomy - overview

Thalamus relays sensory input to the cerebral cortex

cortex

thalamus

nerve fiber from the skin

Page 41: Neuroanatomy - overview

Hypothalamus

Homeostasis

Emotions

Diencephalon

The pituitary gland

Page 42: Neuroanatomy - overview

The “old” view of the limbic system

The anatomy of emotions

Page 43: Neuroanatomy - overview

The “modern” view of the limbic system:

Anterior part: emotions; Posterior part: memory

Amygdala

The anatomy of emotions

Page 44: Neuroanatomy - overview

The anatomy of emotions

The “modern” view of the limbic system:

Anterior part: emotions; Posterior part: memory

Page 45: Neuroanatomy - overview

Different Forms of Memory

Declarative memory Non-declarative memory

Memories that can be

described in words

Can not be described

(e.g how to ride a

bicycle)

Page 46: Neuroanatomy - overview

Brain structures participating in declarative memory:

The posterior part of the limbic system

Hippocampus

Page 47: Neuroanatomy - overview

Brain structures participating in declarative memory:

The posterior part of the limbic system

Page 48: Neuroanatomy - overview

Hippocampus seen from below (parts of the temporal lobes removed)

Page 49: Neuroanatomy - overview

The Brainstem

Mesencephalon

Pons

Medulla oblongata

Page 50: Neuroanatomy - overview

(I. N. Olfactorii)

(II. N. Opticus)

III. N.Oculomotorius

IV. N.Trochlearis

V. N.Trigeminus

VI. N. Abducens

VII. N. Facialis

VIII. N.Vestibulo-

cochlearis

IX. N. Glosso

-pharyngeus

X. N. Vagus

XI. N. Accesorius

XII. N. Hypoglossus

Cranial nerves emerging from the

brainstem mediate sensory and motor

functions in the head

Page 51: Neuroanatomy - overview

The Reticular Formation

Descending part:

Motor functions

Ascending part:

Conciousness

Page 52: Neuroanatomy - overview
Page 53: Neuroanatomy - overview

The Brainstem - Summary

Cranial nerves: sensory and motor functions in the head incl eye

movements, hearing, balance, inner organs

Reticular

Formation: consciousness, motor functions

Dopamine

systems: motivation, reward, motor functions

Serotonin

systems: mood, emotions, hunger-satiety, motor functions

Other

functions: breathing, swalloving

Page 54: Neuroanatomy - overview

Cerebellum

Page 55: Neuroanatomy - overview

Cerebellum: connected to pons via the peduncles

Page 56: Neuroanatomy - overview

Pons

Medulla

oblongata

Peduncle

Page 57: Neuroanatomy - overview

Peduncle

Page 58: Neuroanatomy - overview

Cerebellum

Fine-tuning

of motor

functions

Motor

learning

Cognition

Page 59: Neuroanatomy - overview

The Spinal Cord

Grey matter

White matter

Dorsal horn - sensory

Ventral horn - motor

cervical

lumbar

thoracic

sacral

Page 60: Neuroanatomy - overview

sensory nerves

motor nerves

The Spinal Cord