Neural Basis of the Perceptionand Estimation of Time

SE367 Homework 3

Previous works

Scalar timing theory(Gibbon et al.1984)

Neurophysiological model of timing(Matell &Meck 2004)

EVIDENCE FAVORING ACOMMON TIMING MECHANISM

Work started in late 19th century

Time dependent and time independent sources

Temporal processing

EVIDENCE FAVORING AUBIQUITOUS TIMING ABILITY

OF CORTICAL NETWORKS

Timing is an inherent computational ability of every cortical circuit

Psychophysical experiments suggest that sensory timing is local.

AN INTERMEDIATEHYPOTHESIS

Merchant and colleagues (2008c)

NEUROPHYSIOLOGICAL BASISOF TIME ESTIMATION:

RAMPING ACTIVITY IN THECORE TIMING CIRCUIT

Most studies report climbing activity during a variety of timing tasks.

NEUROANATOMICAL ANDNEUROCHEMICAL SYSTEMS

FOR INTERVAL TIMING

The centrality of the striatum and dopamine (DA) neurotransmission in explicit timing. Frontoparietal systems may govern attention and working memory, which interact with timekeeping processes

FUNCTIONAL SIGNIFICANCE OFBRAIN CIRCUITS THAT GOVERN

INTERVAL TIMING

Pairwise subtractions of brain activation during time discrimination (T), pitch discrimination (P), and the sensorimotor control (C) tasks were conducted for each period.

ILLUSIONS OF TIMEEmerging neuroimaging research suggests that the mechanisms may be partially context dependent.

CONCLUSIONS

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