Nelson's Club Repro Lecture

Download Nelson's Club Repro Lecture

Post on 04-Jul-2015

121 views

Category:

Documents

1 download

Embed Size (px)

TRANSCRIPT

Gynecologic Problems of ChildhoodNelsons Club April 2011

Free Powerpoint Templates

Page 1

Neoplasms Most common gynecologic neoplasm found in children of ovarian origin usually presents as an abdominal mass Ovarian neoplasms constitute 1% of all childhood malignancies 8% of all malignant and abdominal tumors in childrenFree Powerpoint Templates Page 2

Neoplasms Ovarian neoplasms 10-30% of the ovarian neoplasms operated on during childhood or adolescence are malignant Other common neoplasms: Paraovarian tumors Uterine neoplasms

Free Powerpoint Templates

Page 3

Neoplasms Vagina or vulva may also be the site of a benign or malignant lesion in children Cervical dysplasia may occur in adolescents Chemotherapy, especially with alkylating agents is associated with germ cell damage in the postpubertal ovary

Free Powerpoint Templates

Page 4

Neoplasms Prepubertal ovary, on the other hand, is markedly resistant to chemotherapeutic damage of germ cells Survivors of childhood cancer who previously underwent abdominal or gonadal irradiation have an increased rate of spontaneous abortions

Free Powerpoint Templates

Page 5

Ovaries Neonatal and Pediatric Ovarian cysts o most often clinical manifestations of ovarian tumors are abdominal pain, mass, or both Teratoma the most common neoplasm in adolescents; are usually benign -Calcification on abdominal roentgenogram is often a hallmark of a benign teratomaFree Powerpoint Templates Page 6

Ovaries Ovarian adenomas are the second most common benign tumor Ovarian cancers are extremely uncommon in children, but are responsible for 1:500 ovarian malignancies; affect only 4% of women

Free Powerpoint Templates

Page 7

OvariesDysgerminoma - The most common germ cell tumor - Other germ cell tumors are malignant teratomas, endodermal sinus tumors, embryonal carcinomas, mixed cell neoplasms, and gonadoblastomas

Free Powerpoint Templates

Page 8

OvariesImmature teratomas and endodermal sinus tumors - more aggressive malignancies than dysgerminomas - occur in a significantly higher proportion of younger girls (