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NCI Director’s Update National Cancer Advisory Board September 4, 2019 Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Page 1: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

NCI Director’sUpdateNational Cancer Advisory BoardSeptember 4, 2019

Douglas R. Lowy, M.D.Acting Director

@TheNCI@NCIDrDougLowy

Page 2: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Competing R01 applications vs. budgets for NCI & RPGs: Percent change since FY 2013

-10%

0%

10%

20%

30%

40%

50%

60%

2013 2014 2015 2016 2017 2018 2019

NCI R01 Applications

NCI Budgetup 20%

R01 Applications source: NIH RePORTER. 2019 applications estimated.NCI budget shown here is the base appropriation; does not include Cancer Moonshot.

Page 3: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Success Rates for NIH & NCI Grant ApplicationsData include all RPGs, including SBIR/STTR

0%

5%

10%

15%

20%

25%

30%

35%

NCI

24%

Sources: NIH Data Book http://report.nih.gov/nihdatabook/index.aspxand supplemental tables available in RePORT, and NCI DEA.

NIH

32%

27%

21%

Fiscal Year

11%

22%

Page 4: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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What factors have contributed to the dramatic increase in applications to NCI?

Number of unique PI applicants

• Some migrating from other NIH ICs

• Multi-PIs

Applicant Behavior

• Applications per PI

• More PIs with >2 applications per year

Applications to PARs

Low Paylines

Page 5: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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21st Century Cures Act - orangeChildhood Cancer Initiative - green

$4,950$5,215 $5,389

$5,665 $5,744

$5,002

$0

$1,000

$2,000

$3,000

$4,000

$5,000

$6,000

FY 2015 FY 2016 FY 2017 FY 2018 FY 2019 President’s FY 2020 Budget Proposal

FY 2020 HouseMark-up (4/30/2019)

$6,199$400$300

$5,965

NCI Appropriations FY 2015 – 2020 (in millions)

$5,689 $50

$195$5,247

$6,444$195

$50$300

$6,144

Presenter
Presentation Notes
Page 6: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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• Launch date: September 10, 2019

• Primary target audience: NCI grantees, administrators, research grant applicants

• Primary Focus: NCI grants and funding policy updates, fiscal reports and milestones, research activities or priorities that may affect grantees and research applicants

New blog: NCI Bottom Line: A Blog About Grants & More!

Page 7: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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NCI Annual Plan & Budget Proposal (“Bypass”)

Presenter
Presentation Notes
Animated; no click needed. Covers appear in chronological order – oldest first. Just a backdrop to remind participants that we have this opportunity and process each year. These are the past 5 years…put in order. Animate, make current bigger over all of them.
Page 8: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Page 9: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Professional Judgment Budget Proposal Fiscal Year 2021

Page 10: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Highlighted Areas

Page 11: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Ross Brownson, Ph.D.Steven H. and Susan U. Lipstein Distinguished Professor Washington University in St. Louis

Tomi Akinyemiju, Ph.D.Associate ProfessorDuke University

Mark Schiffman, M.D., M.P.H.Senior InvestigatorNational Cancer Institute

Featured Researchers

Page 12: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Childhood Cancer Data Initiative

Tony Kerlavage, Ph.D.Director

Center for Bioinformatics and Information Technology

Jaime Guidry-Auvil, Ph.D.Director

Office of Data Sharing

Presenter
Presentation Notes
Better photo of Tony needed - resolution
Page 13: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Data Registry for Medicare CAR-T patients

“CAR-T cell patient data housed in the Center for International Blood and

Marrow Transplant Research (CIBMTR),

supported by NCI and NHLBI, includes treated patients of Medicare age whoseresults can provide evidence for efficacy

in that population.”

- Jim Doroshow, M.D.,Deputy Director, Clinical

and Translational Research

Page 14: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy
Page 15: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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16 AUGUST 2019VOL 365, ISSUE 6454

Open Access to Cancer Moonshot Publications

Page 16: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Cancer Centers News

IU Simon Cancer Center

Presenter
Presentation Notes
New slide? Better photo of Loehrer, eyes closed in this one. Ask HOllyG.
Page 17: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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https://thehill.com/opinion/education/458292-americas-colleges-and-universities-are-aggressively-addressing-foreign

August 22, 2019By Michael A. McRobbie, President of Indiana University and Morton Schapiro, President of Northwestern University

Page 18: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Recent Leadership Appointments

Deputy Director, NCI – Dinah SingerDirector, Committee Management Office – Joy WiszneauckasDeputy Executive Officer – Eric ColeChief of Staff – Anne Lubenow

Page 19: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Leadership VacanciesDirector, Center for Global Health (CGH)Bob Croyle, Acting

Associate Director, Cancer Therapy Evaluation Program (CTEP)Meg Mooney, Acting

Director, Division of Cancer Prevention (DCP)Debbie Winn, Acting

Director, Division of Cancer BiologyDaniel Gallahan, Acting

Page 20: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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Division of Cancer Biology, Director

•Executive Level Recruitment •The announcement will be open from September 3, 2019 to November 1, 2019.

•https://hr.nih.gov/jobs/search/job-1560101

Page 21: NCI Director’s Update · NCI Director’s Update National Cancer Advisory Board September 4, 2019. Douglas R. Lowy, M.D. Acting Director @TheNCI @NCIDrDougLowy

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