microbial diseases of the skin and eyes
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21. Microbial Diseases of the Skin and Eyes. Warts. Papillomaviruses Treatment Removal – by freezing, burning, or drying Imiquimod (stimulates interferon production) Interferon. Poxviruses. Smallpox (variola) Smallpox virus (orthopox virus) First artificially immunization Monkeypox - PowerPoint PPT PresentationTRANSCRIPT
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings
PowerPoint® Lecture Slide Presentation prepared by Christine L. Case
M I C R O B I O L O G Ya n i n t r o d u c t i o n
ninth edition TORTORA FUNKE CASE
Part B21Microbial
Diseases of the Skin and Eyes
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Warts
Papillomaviruses
Treatment
Removal – by freezing, burning, or drying
Imiquimod (stimulates interferon production)
Interferon
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Poxviruses
Smallpox (variola)
Smallpox virus (orthopox
virus)
First artificially
immunization
Monkeypox
Prevention by smallpox
vaccination
Figure 21.9
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Herpesviruses
Chickenpox
Varicella-zoster virus
(human herpes virus 3)
Transmitted by the
respiratory route
Virus may remain latent
in dorsal root ganglia
Figure 21.10a
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Shingles
Reactivation of latent
HHV-3 releases viruses
that move along
peripheral nerves to skin.
Figure 21.10b
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Herpes Simplex 1 and Herpes Simplex 2
Human herpes virus 1 and HHV-2
Cold sores or fever blisters (vesicles on lips) HHV-1
Herpes gladiatorum
Herpes whitlow
Herpes encephalitis (HHV-2 has up to a 70%
fatality rate)
HHV-1 can remain latent in trigeminal nerve ganglia.
HHV-2 can remain latent in sacral nerve ganglia.
Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings Figure 21.11
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Measles (Rubeola)
Measles virus
respiratory route
Macular rash
Prevented by vaccination.
MMR
(Measles, Mumps, Rubella)
Figure 21.14
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Measles (Rubeola)
Figure 21.13
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Rubella (German Measles)
Rubella virus
Macular rash and fever
Congenital rubella
syndrome causes severe
fetal damage.
Prevented by vaccination
Figure 21.15
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Cutaneous Mycoses
Dermatomycoses: Tineas or ringworm
Metabolize keratin
Treatment
Oral griseofulvin
Topical miconazole and clotrimazole
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Candidiasis
Candida albicans (yeast)
Candidiasis may result from suppression of competing
bacteria by antibiotics.
Occurs
Skin, mucous membranes, and mouth
Thrush
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Candidiasis
Figure 21.17
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Scabies
Sarcoptes scabiei burrows in the skin to lay eggs
Treatment with topical insecticides
Figure 21.18
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Pediculosis
Pediculus humanus
capitis (head louse)
P. h. corporis (body louse)
Feed on blood.
Lay eggs (nits) on hair.
Treatment with topical
insecticides.
Figure 21.19
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Bacterial Diseases of the Eye
Conjunctivitis (pinkeye)
Haemophilus influenzae
Various microbes
Associated with unsanitary contact lenses
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Bacterial Diseases of the Eye
Chlamydia trachomatis
Trachoma
Leading cause of blindness worldwide
Infection causes permanent scarring; scars
abrade the cornea leading to blindness