metabolisme lysine 2

7/26/2019 Metabolisme Lysine 2

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METABOLISMELYSINEOleh :

Helda Dwi H 081524253003

Denok Risky A.P 081524253007


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Gambaran Umum

Asam amino:asamoranik yan menand!n:

"gugus amino"gugus karboksil."atom hidrogn dan"gugus !#ran$aisam%in& %em'eda

Asam amino snsial


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Biosintsis Lisin

(!m'

er : )O*R+A, O- A/RO,O )!ly 2010 %. 330463310


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Biosintsis Lisin "adaukar#oti$ alga

(!m'er : Reiew e$a'oli$es 2013 3 294311; doi:10.3390


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halassiosira %se!donana

Phaeodactylum tricornutum

Amino A$id Bios#nthsis%ath(a#s in )iatoms

e$a'oli$es 2013 3 294311;doi:10.3390


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Biosintsis Lisin "adabaktri

(!m'er : )O*R+A, O- A/RO,O )!ly 2010 %. 330463310


7/26(!m'er : )O*R+A, O- A/RO,O )!ly 2010 %. 330463310

Lanjutan BiosintsisLisin "ada baktri


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En*#m )+)%S


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Mkanism katalitik En*im)+)%S


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,ontrol !gulasi Biosintsis AALisin


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-eed'a=knhi'i$ion

,ontrol !gulasi Biosintsis AA Lisin


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-ungsi Lisin

!n$!k sin$esis %ro$ein

'er%eran %en$in dalam %enyediaan eneri%er$!m'!han $!lan dan %em'en$!kan o$o$

(e'aai %re=!rsor %em'en$!kan karnitin


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arnitin


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Dies$ion o>Pro$eins


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n h!mans ,ysine is an essen$ial amino a=id and$here is no ,ysine 'iosyn$he$i= ma=hinery. Howeerh!mans do derade ,ysine.

he main =a$a'oli= %a$hway >or ,ysine ia(a==haro%ine #e+#,l!$aryl2&,lysine& is ami$o=hondrial %a$hway leadin $o $he >orma$ion o>A=e$yl/oA #A=e$yl/oen?ymeA&.

Deradasi ,isin dalam !'!h an!sia


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L#sin atabolismSa$$haro"in "ath(a# in Li&r +uman

(!m'er : hesis. 2011. P!'lished arenPa$ri=ia /ha%man.


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Pro$ein and lysine reB!iremen$s o>in>an$s =hildren adoles=en$s and

ad!l$s

he lysinereB!iremen$ ishiher in in>an$s

$han in ad!l$s andre=en$re=ommenda$ionsindi=a$ed a lysinereB!iremen$ $ha$ranes >rom C4man$and ad!l$ #18 y&.

(!m'er : he )o!rnal o> +!$ri$ion. 2007. P!'lished 'y Ameri=an (o=ie$y >or +!$ri$ion.


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,atabolism L#sin

2)O*R+A, O- A/RO,O +o. 2005 %. 750067510. Ameri=an (o=ie$y >or i=ro'ioloy.(!m'er :

1

)O*R+A, O- A/RO,O +o. 2005 %. 750067510. Ameri=an (o=ie$y >or i=ro'ioloy.


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L#sin atabolism "ath(a#

(!m'er : he ( )o!rnal #2013& 7 240062410 E 2013 n$erna$ional (o=ie$y >or i=ro'ial =oloy All rih$sresered


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L#sin atabolism AM/ "ath(a#

(!m'er : )O*R+A, O- A/RO,O +o. 2005 %. 750067510. Ameri=an (o=ie$y >or i=ro'ioloy.


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L#sin atabolismSa$$haro"in "ath(a# in ba$tria

(!m'er : -edera$ion o> !ro%ean io=hemi=al (o=ie$ies. 2012. P!'lished 'y lseier .F. All rih$s


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L#sinatabolism

Sa$$haro"in"ath(a# in %lant

1& lysine6ke$ol!$ari=a=id red!=$ase #,R& sa==haro%inedehydroenase #(DH& aminoadi%i= a=idsemialdehydedehydroenase#AADH& aminoadi%i= a=idamino$rans>erase#AAA& eneral aamino

a=id $ransaminase.

(!m'er : Reiew. 2000. P!'lished 'ylseier .F. All rih$s resered.


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(!mmary o> derada$ion

lysine in %lan$ and animal he sa==haro%ine %a$hway also eGis$s in %lan$s and

animals '!$ ins$ead o> >!n=$ionin in lysinesyn$hesis i$ works in $he reerse rea=$ion leadin

$o lysine derada$ion. n $he dire=$ion o>derada$ion $he rs$ $wo en?yma$i= s$e%s =an 'eiewed as an a$y%i=al $ransamina$ion rea=$ion inwhi=h $he aamino ro!% o> lysine is $rans>erred $oake$ol!$ara$e $o >orm l!$ami= a=id.


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RA A(Hy : Helda dan Denok

metabolisme lysine 2

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