may 2014 new in review

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FROM THE ACADEMY New in Review PERIODICALS BUSINESS AND INDUSTRY The new food package and breastfeed- ing outcomes among women, infants, and children participants in Los Angeles County. Langellier BA, Chaparro P, Wang MC, Koleilat M, Whaley SE. Am J Public Health. 2014;104(S1): S112-S118. Modeling potential effects of reduced calories in kidsmeals with toy giveaways. Freij MY, Sell RL, Bozack AK, Weiss LJ, Garcia AC. Childhood Obesity. 2014;10(1):58-63. Abstract. Fast-food marketing directed to children often includes a toy as an incentive, but little research is available to understand this policy in conjunction with reduced calorie content. This dy- namic model study created a potential mathematical model derived after an intensive literature review of the effect of a theoretical legal ordinance of calorie reduction of childrens fast-food meals on childhood obesity. The authors ap- plied their model to New York City, where 33% of children are obese. Se- lected assumptions were used to drive the data collection, including limiting the data to children 12 years of age, pro- jecting consumption of fast food similar to the National Health and Nutrition Ex- amination Survey (NHANES) 2007-2008, using marketing data of toy giveaway childrens meals sold in 2009, and noting frequency of purchase. Using these rules, a model was created based on approxi- mately 163,571 New York City children who would save 66 calories per meal (based on a theoretical 616 calories in a regular meal now reduced to 550 to qualify for a toy giveaway), weighted by estimated frequency of weekly meal consumption stratied by age groups. The dynamic model estimated children could avert a weight gain of approxi- mately 27 pounds per year assuming all other food intake remained the same if toys were used only as an incentive for reduced-calorie childrens fast food meals. Limitations included inability to assess nutritional value, true consump- tion of lower calorie meal option, and true effect based on unknown body weight of actual children. Funding was provided by the New York State Depart- ment of Health to the New York Academy of Medicine. Nutrition labeling and the choices logo in Israel: Positions and perceptions of leading health policy makers. Gesser-Edelsburg A, Endevelt R, Tirosh- Kamienchick Y. J Hum Nutr Diet. 2014;27(1): 58-68. Choosing the right customer: The rst step in winning strategy. Simons R. Harv Bus Rev. 2014;92(3):49-55. CLINICAL NUTRITION Effectiveness of Tai Chi and Qigong on chronic obstructive pulmonary disease: A systematic review and meta-analysis. Ding M, Zhang W, Li K, Chen X. (Systematic Review, Meta-Analysis). J Alternative Comple- mentary Med. 2014;20(2):79-86. Conclusiveness of the Cochrane Re- views in Nutrition: A systematic review. Cohen S, Mandel D, Minouni FB, Marom R, Lubetzky R. (Systematic Review). Eur J Clin Nutr. 2014;68(2):143-145. (OPEN ACCESS) Habitual diets rich in dark-green vege- tables are associated with an increased response to u-3 fatty acid supplemen- tation in Americans of African American ancestry. OSullivan A, Armstrong P, Schuster GU, et al. J Nutr. 2014;144(2):123-131. Abstract. Cultural food habits may have actual genetic origins in absorption and bioavailability of selected nutrients. This secondary analysis of a 6-week random- ized, double-blind, placebo-controlled prospective interventional trial examined the variation of gene response to n-3 fatty acid supplementation or placebo in a cohort of 83 healthy adult African Americans with low habitual n-3 dietary intake. Food intake was assessed by the Block food frequency questionnaire version 2005. Baseline and end-of-study data were collected for serum lipids, monocyte 5-lipoxygenase, anthropomet- rics, and blood pressure. Low and high responders were determined by change in red blood cell counts and erythrocyte lipid levels. Data were analyzed using a mixed-mode linear regression model. Results showed similar total diet quality among groups, but the low responders were more likely to consume decreased amounts of dark green vegetables, or- ange vegetables, and legumes at base- line. (P¼0.01 to 0.002) High responders were more likely to show decreases in plasma triglycerides and very-low- density lipoprotein particles size. The mechanism for this variation is un- known. Due to the associative nature of the ndings, prospective research is required to conrm. Funding was pro- vided by the National Institutes of Health through the University of California- Davis Center of Excellence in Nutritional Genomics. Irisin in humans: Recent advances and questions for future research. Boström PA, Fernández-Real JM, Mantzoros C. (Editorial). Metabolism. 2014;63(2):178-180. Diet quality is associated with circu- lating C-reactive protein but not irisin levels in humans. Park KH, Zaichenko L, Peter P, Davis CR, Crowell JA, Mantzoros CS. Metabolism. 2014; 63(2):233-241. IN THIS ISSUE PERIODICALS................................................................................................. page 812 SITES IN REVIEW ......................................................................................... page 819 New in Review Editor: Judith Beto, PhD, RD, FADA Sites in Review Editor: Donna L. Hollinger, MS, RDN, LD Order Abstracted Articles at a Discount Did you know you can order the articles listed in New in Review through the Academy? You can for a nominal charge of $10. Simply e-mail a citation from New in Review (eg, Stensland SH, Sobal J. Dietary practices of ballet, jazz, and modern dancers. J Am Diet Assoc. 1992;92(3):319-324) to [email protected]. You will then be sent a link to pay for your article using a credit card. Articles are sent via e-mail and generally arrive within 3 business days. 812 JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS ª 2014 by the Academy of Nutrition and Dietetics.

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Page 1: May 2014 New in Review

FROM THE ACADEMY

IN THIS ISSUEPERIODICALS...................SITES IN REVIEW ...........New in Review Editor: JuSites in Review Editor: D

Order Abstracted ArticleDid you know you can oAcademy? You can for ain Review (eg, Stenslanddancers. J Am Diet Assocbe sent a link to pay forand generally arrive wit

812 JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS

New in Review

PERIODICALS

BUSINESS AND INDUSTRY

.............................................................................. page 812.............................................................................. page 819dith Beto, PhD, RD, FADAonna L. Hollinger, MS, RDN, LD

s at a Discountrder the articles listed in New in Review through thenominal charge of $10. Simply e-mail a citation from NewSH, Sobal J. Dietary practices of ballet, jazz, and modern

. 1992;92(3):319-324) to [email protected]. You will thenyour article using a credit card. Articles are sent via e-mailhin 3 business days.

The new food package and breastfeed-ing outcomes among women, infants,and children participants in Los AngelesCounty.Langellier BA, Chaparro P, Wang MC, Koleilat M,Whaley SE. Am J Public Health. 2014;104(S1):S112-S118.

Modeling potential effects of reducedcalories in kids’ meals with toygiveaways.Freij MY, Sell RL, Bozack AK, Weiss LJ, Garcia AC.Childhood Obesity. 2014;10(1):58-63.Abstract. Fast-food marketing directedto children often includes a toy as anincentive, but little research is availableto understand this policy in conjunctionwith reduced calorie content. This dy-namic model study created a potentialmathematical model derived after anintensive literature review of the effectof a theoretical legal ordinance of caloriereduction of children’s fast-food mealson childhood obesity. The authors ap-plied their model to New York City,where 33% of children are obese. Se-lected assumptions were used to drivethe data collection, including limiting thedata to children �12 years of age, pro-jecting consumption of fast food similarto the National Health and Nutrition Ex-amination Survey (NHANES) 2007-2008,using marketing data of toy giveawaychildren’s meals sold in 2009, and notingfrequency of purchase. Using these rules,a model was created based on approxi-mately 163,571 New York City childrenwho would save 66 calories per meal(based on a theoretical 616 calories in aregular meal now reduced to 550 toqualify for a toy giveaway), weightedby estimated frequency of weekly mealconsumption stratified by age groups.The dynamic model estimated childrencould avert a weight gain of approxi-mately 27 pounds per year assumingall other food intake remained the sameif toys were used only as an incentivefor reduced-calorie children’s fast foodmeals. Limitations included inability toassess nutritional value, true consump-tion of lower calorie meal option, andtrue effect based on unknown bodyweight of actual children. Funding wasprovided by the New York State Depart-ment of Health to the New York Academyof Medicine.

Nutrition labeling and the choices logoin Israel: Positions and perceptions ofleading health policy makers.Gesser-Edelsburg A, Endevelt R, Tirosh-Kamienchick Y. J Hum Nutr Diet. 2014;27(1):58-68.

Choosing the right customer: The firststep in winning strategy.Simons R. Harv Bus Rev. 2014;92(3):49-55.

CLINICAL NUTRITION

Effectiveness of T’ai Chi and Qigong onchronic obstructive pulmonary disease:A systematic review and meta-analysis.Ding M, Zhang W, Li K, Chen X. (SystematicReview, Meta-Analysis). J Alternative Comple-mentary Med. 2014;20(2):79-86.

Conclusiveness of the Cochrane Re-views in Nutrition: A systematic review.Cohen S, Mandel D, Minouni FB, Marom R,Lubetzky R. (Systematic Review). Eur J ClinNutr. 2014;68(2):143-145. (OPEN ACCESS)

Habitual diets rich in dark-green vege-tables are associated with an increasedresponse to u-3 fatty acid supplemen-tation in Americans of African Americanancestry.O’Sullivan A, Armstrong P, Schuster GU, et al.J Nutr. 2014;144(2):123-131.Abstract. Cultural food habits may haveactual genetic origins in absorption andbioavailability of selected nutrients. Thissecondary analysis of a 6-week random-ized, double-blind, placebo-controlled

ª 2

prospective interventional trial examinedthe variation of gene response to n-3fatty acid supplementation or placebo ina cohort of 83 healthy adult AfricanAmericans with low habitual n-3 dietaryintake. Food intake was assessed bythe Block food frequency questionnaireversion 2005. Baseline and end-of-studydata were collected for serum lipids,monocyte 5-lipoxygenase, anthropomet-rics, and blood pressure. Low and highresponders were determined by changein red blood cell counts and erythrocytelipid levels. Data were analyzed using amixed-mode linear regression model.Results showed similar total diet qualityamong groups, but the low responderswere more likely to consume decreasedamounts of dark green vegetables, or-ange vegetables, and legumes at base-line. (P¼0.01 to 0.002) High responderswere more likely to show decreasesin plasma triglycerides and very-low-density lipoprotein particles size. Themechanism for this variation is un-known. Due to the associative nature ofthe findings, prospective research isrequired to confirm. Funding was pro-vided by the National Institutes of Healththrough the University of California-Davis Center of Excellence in NutritionalGenomics.

Irisin in humans: Recent advances andquestions for future research.Boström PA, Fernández-Real JM, Mantzoros C.(Editorial). Metabolism. 2014;63(2):178-180.

Diet quality is associated with circu-lating C-reactive protein but not irisinlevels in humans.Park KH, Zaichenko L, Peter P, Davis CR,Crowell JA, Mantzoros CS. Metabolism. 2014;63(2):233-241.

014 by the Academy of Nutrition and Dietetics.

Page 2: May 2014 New in Review

FROM THE ACADEMY

Ability of vitamin D to reduce in-flammation in adults without acuteillness.Zanetti M, Harris SS, Sawson-Hughes B.(Review). Nutr Rev. 2014;72(2):95-98.

COMMUNICATION/PUBLICATION

Effective writing and publishing scien-tific papers, part XI: Submitting a paper.Kotz D, Cals JW. J Clin Epidemiol. 2014;67(2):123.

Socialmediaandmedicalprofessionalism.Cunningham A. Med Educ. 2014;48(2):110-112.

What is appropriate to post on socialmedia? Ratings from students, facultymembers, and the public.Jain A, Petty EM, Jaber RM, et al. Med Educ.2014;48(2):157-169.

COMMUNITY NUTRITION

The effects of breastfeeding exclusivityon early childhood outcomes.Jenkins JM, Foster EM. Am J Public Health.2014;104(S1):S128-S135.Abstract. Community-based interventionscan have measurable effects on long-termoutcomes but are difficult to measure dueto uncontrolled free-living environment.This secondary analysis of the Early Child-hood Longitudinal StudyeBirth Cohortdatabase evaluated the effect of exclusivebreastfeedingdurationonchildhoodhealthand cognitive measures at 2 and 4 yearsof age. Data were collected from parentinterviews and childhood assessments atages of 9 months, 2 years, 4 years, andkindergarten entrance. Statistical analysisused a weighted inverse probability least-squares regression treatment propensityscore method to adjust for duration ofbreastfeeding on outcomes. Nine exclusivecategories of breastfeeding were used,ranging from never (including nonexclu-sive) to>7months. Sensitivity analysis wasused to evaluate for effect of low birthweight and maternal obesity. Data wereavailable for 10,700 nationally-representedchildren born in the year 2001 at 9 monthswith decreased complete data in subse-quent time intervals varying from 7,150 to8,700 children. Results showed no conclu-sive relationship with duration of breast-feeding at age 4 years, with some effect atage 2 years. No doseeresponse relationshipwas seen for mental, motor, body mass in-dex, math, or reading. The lack of a clearrelationship may be confounded by thewide array of uncontrolled variables duringthe more than 4 years of study. No fundingwas provided for this analysis.

May 2014 Volume 114 Number 5

A pilot study of the effecs of a tailoredweb-based intervention on promotingfruit and vegetable intake in AfricanAmerican families.Wilson DW, Alia KA, Kitzman-Ulrich H, Resnicow K.Childhood Obesity. 2014;10(1):77-84.

CONSULTATION AND PRIVATEPRACTICE

View of patients and general dentalpractitioners on the organizational as-pects of a general dental practice.Sonneveld R, Brands W, Vronkhorst E, Truin GJ.Health Expectations. 2014;17(1):129-137.

A comparison of general practitionersprescribing of gluten-free foods forthe treatment of coeliac disease withnational prescribing guidelines.Martin U, Mercer SW. J Hum Nutr Diet. 2014;27(1):96-104.

CULINARY

Pairing vegetableswith a liked food andvisually appealing presentation: Prom-ising strategies for increasing vegetableconsumption among preschoolers.Correia DC, O’Connell M, Irwin ML, HendersonKE. Childhood Obesity. 2014;10(1):72-76.Abstract. Children as well as adultsare affected by the visual presentationof food, but less research has been con-ducted on children regarding changesin intake. This community-based ran-domized clinical study compared theeffectiveness of two presentation inter-ventions (pairing of a vegetable with aknown, familiar liked food or enhancingthe visual presentation of that food) onthe consumption and willingness to trya cohort of vegetables in a preschoolsetting. The study was conducted in asingle racially diverse Connecticut USDepartment of Agriculture Child andAdults Care Food Program (CACFP). Theoutcome measures were willingness totaste of at least 3 g of a presented fooditem and total consumption of the testvegetable in grams. Samples were pre-weighed and plated for presentation,then post-weighed after consumption onelectronic scales. Children were servedboth a lunch and snack presentation.Lunch included a small pizza with eitherbroccoli on the side (control) or onthe pizza (intervention). The snack wascucumber circles on a dish (control) orarranged as a caterpillar with a chiveantennae and an olive eye (intervention).A one-factor, two-level within-subjectsdesign was used with McNemar’s testfor paired proportions and paired t-testsbetween control/intervention. Results

JOURNAL OF THE ACAD

were available for 42 children (mean age4.4 years, 16.4% obese or overweight,41% African American, 14% Hispanic, 66%male) from a sample of 57. Consumptionwas not statistically significant betweencontrol and intervention, but trended to-ward intervention. A greater willingnessto try (95% vs 79%) was seen with in-tervention. Funding was provided bythe Robert Wood Johnson FoundationHealthy Eating Research program as partof a larger study protocol.

Effects of improved fat content onfrankfurters and pates on lipid and lipo-protein profile of volunteers at increasedcardiovascular risk: Aplacebo-controlledtrial.Delgado-Pando G, Celanda P, Sánchez-Muniz F,Jiménez-Colmenero F, Olmedilla-Alonso B. EurJ Nutr. 2014;53(1):83-93.

Different postprandial actue responsein healthy subjects to three strawberryjams varying in carbohydrate and anti-oxidant content: A randomized, cross-over trial.Ibero-Baraibar I, Cuervo M, Navas-Carretero S,et al. Eur J Nutr. 2014;53(1):201-210.

DIABETES CARE

Diabetes: Complications and theeconomic burden.Meetoo D. Brit J Healthcare Manage. 2014;20(2):60-67.

Higher magnesium intake reducesrisk of impaired glucose and insulinmetabolism and progression fromprediabetes to diabetes in middle-aged Americans.Hruby A, Meigs JB, O’Donnell CJ, Jacquews PF,McKeown NM. Diabetes Care. 2014;37(2):419-427.Abstract. Magnesium may be a key nu-trient in glucose metabolism, and ade-quate intake may affect pre-diabetesprogression. This secondary analysisof the Framingham Heart Study Off-spring Cohort database representing2,582 community-dwelling adults (aged26 to 81 years at baseline, mean age 54years, 55% women, 42% overweight, 21%obese) examined changes over 7 yearsbetween magnesium intake, diabetesincidence, and key metabolic variables(glucose, insulin, insulin sensitivity). Aglucose tolerance test was administeredat exam 5 of the protocol. Magnesiumintake was assessed using a semi-quantitative 126-item validated food fre-quency questionnaire at each protocolvisit. Data analysis included use of mag-nesium intake quintiles adjusted by

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FROM THE ACADEMY

814 JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS

energy intake with adjustment for po-tential confounding variables, withglucose intolerance as a grouping variableusing linear regression modeling. Resultscalculated average daily magnesiumintake as 308 mg/d, with 50% of womenand 75% of men consuming below Rec-ommended Dietary Allowance level. Sta-tistical adjustment for dietary fiber didnot alter the results. A longitudinal asso-ciation between higher dietary magne-sium intake and a 37% lower risk of type 2diabetes was identified. Funding wasprovided by the National Heart, Lung, andBlood Institute and the US Department ofAgriculture.

Dietary patterns and glycemic controland compliance todietary advice amongfasting patients with diabetes duringRamadan.Hakeem R, Ahmedani MY, Alvi SF, UlhaqueMS, Basit A, Fawwad A. Diabetes Care. 2014;37(2):e47-e48.

Type 1 diabetes, metabolic syndromeand cardiovascular disease.Chillardin JJ, Le-Roux JA, Benaiges D,Pedro-Bolet J (Review). Metabolism. 2014;63(2):181-187.

EDUCATION

Making students do the thinking:Team-based learning in a laboratorycourse.Simonson SR. Adv Physiol Educ. 2014;38(1):49-55.Abstract. Team-based learning (TBL) is apedagogy that focuses on four steps: 1)student teams, 2) accountability as aunit, 3) constant feedback cycles, and4) common assignments. This researchreport describes TBL within a graduateexercise physiology laboratory courseat Boise State University, Boise, ID, usinga two-step readiness assurance testing(RAT) strategy. RAT consisted of a shortmultiple-choice test, first taken as an in-dividual (iRAT) and then as a team (tRAT).A scoring system of 1 to 4 points was usedto rate how many attempts were neededto select the correct answer. Immediateanswers were assessed using a scratch-off system in conjunction with an ap-peals procedure. Teams also collaboratedon how to rate their participation andgrade weighing. The final exam wasindividually completed as an open book,cumulative, practical application directedformat. Evaluation used both studentand instructor qualitative responses. Stu-dents felt the RAT system was more time-intensive but allowed more connectivelearning. Instructors also believed theinitial time investment was very high. Theneed to write excellent questions to meet

May 2014 Volume 114 Number 5

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FROM THE ACADEMY

the RAT format and content was crucial.No funding support was identified.

Authentic clinical experiences anddepth in systems: Toward a 21st centurycurriculum.Gonzalo JD, Haidet P,WolpawDR. (Commentary).Med Educ. 2014;48(2):104-105.

Methods of teaching medical traineesevidence-based medicine: A systematicreview.Ilis D, Maloney S. (Systematic Review). MedEduc. 2014;48(2):124-135.

GERONTOLOGY

Type 2 diabetes is associated with lowmuscle mass in older adults.Kim KS, Park KS, Kim MJ, Kim SK, Cho YW, ParkSW. Geriatr Gerontol Int. 2014;14(S1):115-121.

Construct validity and reliability of atwo-step tool for the identification offrail older people in primary care.van Kempen JA, Schers HJ, Melis RJ, RikkertMG. J Clin Epidemiol. 2014;67(2):176-189.

LONG-TERM CARE

Body mass index, weight change, andclinical progression in mild cognitiveimpairment and Alzaheimer disease.Besser LM, Gill DP, Monsell SE, et al. AlzheimerDis Assoc Disorders. 2014;28(1):36-43.

The effect of posture on body circum-ference in older adults.Sousa AS, de Sousa OL, Amaral TF. J HumanNutr Diet. 2014;27(1):80-87.Abstract. Changes inbodycomposition areimportant tracking measures in long-termcare, but accurate assessment is essentialto data collection. This cross-sectionalstudy of 102 older adults (mean age 77years, 67% women) residing in care homes(n¼69) or tertiary hospitals (n¼35) inPortugal was conducted to determine theeffect of body position and symmetry ongirth measurement. Measures were takenof left and right arms, waist, hip mid-thigh,and calf, with each subject both standingand in a supine position. Height andweightwere measured using a wall stadiometeror a digital scale. The Mini-Nutritional As-sessment (MNA) short-form score andNHANES IV percentiles were used as com-parison references. Data were comparedbetween body positions using c2 and Stu-dent’s paired t-tests along with intraclasscorrelation coefficients. Participants wereclassified by the MNA as undernourished(23.5%) or at risk for undernutrition (51%)at the time of measurement. Resultsshowed no statistical differences between

May 2014 Volume 114 Number 5

body position on intraclass correlation co-efficients for all measures. No fundingsupport was identified.

MANAGEMENT/ADMINISTRATION

Manage your work, manage your life.Groysberg B, Abrahams R. Harv Bus Rev.2014;92(3):58-66.

Who’s got those top jobs? Executiveprofiles and career paths continue toevolve.Cappelli P, Hamori M, Bonet R. Harv Bus Rev.2014;92(3):75-79.

A performance-based approach toproject assignment and performanceevalution.Xu Y, Yeh CH. Int J Project Manage. 2014;32(2):218-222.

Project risk management methodologyfor small firms.Marcelino-S�adaba S, Pérez-Ezcurdia A, LazcanoAM, Villanueva P. Int J Project Manage.2014;32(2):327-340.

NUTRITION SUPPORT

Enteral zinc supplementationandgrowthin extremely-low-birth-weight infantswith chronic lung disease.Shaikhkhalil AK, Curtiss J, Puthoff TD, Valentine CJ.J Pediatr Gastroenterol Nutr. 2014;58(2):183-187.

Intestinal alkaline phosphatase: Novelfunctions and protective effects.Lallés JP. (Review). Nutr Rev. 2014;72(2):82-94.

Pediatric palliative care and pediatricmedical ethics: Opportunities andchallenges.Supplement. Pediatrics. 2014;133(S1):S1-S49.

ONCOLOGY

Costs and outcomes evaluation of pa-tient navigation after abnormal cancerscreening. Evidence from the PatientNavigation Research Program.Bensink ME, Ramsey SD, Battaglia T, et al.Cancer. 2014;120(4):570-578.Abstract. The Patient Navigator ResearchProgram is a government-sponsoredresearch initiative to study whether pa-tient navigators (professional healthworkers or trained laymen) paired withpotentially underserved patients wouldreduce health access disparities by in-creasing cancer screening. This analysisfocused on the economic impact of this

JOURNAL OF THE ACAD

patient navigator concept within a 2006-2010 multi-centered (n¼9) prospectiverandomized study between the navigatorgroup (n¼5,063) and the usual-caregroup (n¼5,458). Outcome cost variableswere direct medical expenses, patienttime and travel, and time from screeningto treatment. Data were analyzed usingindependent c2 between groups alongwith multi-level mixed-effects linearregression models using probability ofresolution with time duration categories.Costs were estimated for training, di-rect use, and future maintenance.The demographics included 32% AfricanAmerican and 39% Hispanic patients.Approximately 11% to 12% of screeningpatients had a cancer diagnosis. The costto train a navigator was $2,460, with amean per patient cost of $130 to $190(range $60 to $450). Navigated patientshad trends of higher mean testing costs,higher patient time costs, and lower daysto resolution duration compared with theusual care group. The small increase inbenefit with navigators did not changecancer outcome. Funding support wasprovided from the National Cancer Insti-tute Center to Reduce Cancer Health Dis-parities contract grant.

Acceptance of a community-basednavigator program for cancer controlamong urban African Americans.Halbert CH, Briggs V, Bowman M, et al. HealthEduc Res. 2014;29(1):97-108.

Effective communication about theuse of complementary and integrativemedicine in cancer care.Frenkel M, Cohen L. (Review). J AlternativeComplementary Med. 2014;20(1):12-18.

PEDIATRIC

Diagnostic and prognostic value ofprocalcitonin and C-reactive protein inmalnourished children.Page AL, de Rekeneire N, Sayadi S, et al.Pediatrics. 2014;133(2):e363-e370.Abstract. The biomarkers of procalcitoninand C-reactive protein often denoteinflammation, but have never beenclearly correlated to childhood malnutri-tion as a potential marker of increasedrisk for infection. This prospectiveconsecutively-enrolled clinical study wasconducted within a single inpatient ther-apeutic feeding center in Maradi, Niger,from 2007 to 2008. This secondary anal-ysis reviewed the baseline data for all311 enrolled children (aged 6 to 39months, median age 13 months) hospi-talized with severe acute malnutrition(defined as weight-for-height <3 z-score,and/or mid-upper arm circumference<110 mm and/or bilateral edema)with at least one additional medical

EMY OF NUTRITION AND DIETETICS 815

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FROM THE ACADEMY

complication. Data were available forclinical exam upon admission; laboratoryparameters (blood, urine, stool), chestx-ray, and blood cultures. Statistical anal-ysis grouped the children by five infectiongroups determined by culture of stool orblood. Groups were compared by c2,Fisher’s exact, and Kruskall-Wallis tests.Receiver operating characteristic (ROC)curves were plotted using procalcitoninand C-reactive levels. A total of 256 chil-dren had complete data for analysis. Thehighest biomarker levels were seenwith bacteremia or pneumonia. C-reactiveprotein threshold of 40 mg/L was thestrongest predictor of mortality (81%sensitivity, 58% specificity). These twobiomarkers were not statistically valid fordiagnosing invasive bacterial infections,but C-reactive protein could be useful inassessing severity of prognosis. Fundingfor this analysis was supported by theMédecins Sans Frontiéres and Epicentreteams in both Paris, France, and Maradi,Niger.

Intermittent maple syrup urine disease:Two case reports.Axler O, Holmquist P. Pediatrics. 2014;133(2):e458-e460.

POLICY & ADVOCACY

Fortification: New findings andimplications.Dwyer JT, Woteki C, Bailey R, et al. (Review).Nutr Rev. 2014;72(2):127-141.

PUBLIC HEALTH

Toward a national strategy on infantmortality.Lu MC, Johnson KA. Am J Public Health.2014;104(S1):S13-S16.

Moving towards evidence-based Fed-eral Healthy Start Program evaluations:Accounting for bias in birth outcomesstudies.Meghea CI, Raffo JE, VanderMeulen P, Roman LA.Am J Public Health. 2014;104(S1):S25-S27.

RENAL NUTRITION

L-carnitine supplementation for adultswith end-stage kidney disease requiringmaintenance hemodialysis: A system-atic review and meta-analysis.Chen Y, Abbate M, Tang L, et al. (SystematicReview, Meta-analysis). Am J Clin Nutr. 2014;99(2):408-422.

May 2014 Volume 114 Number 5

Effect of a cooked meat meal on serumcreatinine and estimated glomerfularfiltration rate in diabetes-related kid-ney disease.Nair S, O’Brien SV, Hayden K, et al. DiabetesCare. 2014;37(2):483-487.Abstract. Serum creatinine is an impor-tant laboratory test to assess renal func-tion by estimating glomerular filtrationrate (GFR), but fasting prior to blooddraw is seldom instructed. This prospec-tive four-factor experimental clinicalstudy compared the calculated GFR be-tween diabetics in four stages (1-4) ofchronic kidney disease (n¼60) and acohort of non-diabetic healthy controls(n¼20) with and without a pre-lab drawstandardized cooked-meat meal. Testmeals each contained 44 g protein meal asa beef burger or a vegetarian burger alongwith buns, vegetable salad, and water(total 54 g protein). Meals were servedeither the evening before blood draw orthe morning of a blood draw after anovernight fast. Data were compared byWilcoxon signed rank test and paired t-tests. Results showed meat consumptionsignificantly increased serum creatinineand estimated a significantly lower GFRestimation in all stages of chronic kidneydisease, particularly in stage 3. GFR esti-mate variation at stage 4 was least vari-able. Similar increases were seen inhealthy volunteers. Differences abated af-ter 4 hours post ingestion and werenot detectable after 12 hours. No differ-ences were seen after a nonmeat meal. Nofunding source was identified; researchwas conducted in Liverpool, UK, withinNational Health Service Foundation TrustHospitals.

RESEARCH

Review of mixed treatment com-parisons in published systematicreviews shows marked increasesince 2009.Lee AW. (Review). J Clin Epidemiol. 2014;67(2):138-143.

“Bird in hand” cash was more effec-tive than prize draws in increasingphysician questionnaire response.Drummond FJ, O’Leary E, O’Neill C, Burns R,Sharp L. J Clin Epidemiol. 2014;67(2):228-231.

Identification and pharmacokinetics ofnovel alkylresorcinol metabolites in hu-man urine, new candidate biomarkersfor whole-grain wheat and rye intake.Zhu Y, Skurlknight KL, Chen X, Sang S. J Nutr.2014;144(2):114-122.

JOURNAL OF THE ACAD

Predicting muscle mass from anthop-ometry using magnetic resonanceimaging as a reference: A systematicreview.Al-Gindan YY, Hankey CR, Leslie W, Govan L,Lean ME. (Systematic Review). Nutr Rev. 2014;72(2):113-126.

SCHOOL NUTRITION

School year versus summer differencesin child weight gain: A narrative review.Baranowksi T, O’Connor T, Johnston C, et al.(Review). Childhood Obesity. 2014;10(1):18-24.

School-based health promotion andphysical activity during and afterschool hours.Vander Ploeg KA, McGavock J, Maximova K,Veugelers PJ. Pediatrics. 2014;133(2):e371-e378.

SPORTS NUTRITION

The effects of high-intensity exerciseon neural responses to images offood.Crabtree DR, Chambers ES, Hardwick RM,Blannin AK. Am J Clin Nutr. 2014;99(2):258-267.

Leucine supplementation of a low-protein mixed macronutrient beverageenhances myofibrillar protein synthesisin young men: A double-blind, ran-domized trial.Churchward-Venne TA, Breen L, Donato DM,et al. Am J Clin Nutr. 2014;99(2):276-286.

Contribution of creatine to proteinhomeostasis in athletes after endur-ance and sprint running.Tang, FC, Chan CC, Kuo PL. Eur J Nutr.2014;53(1):61-71.

WEIGHT MANAGEMENT

Willingness to pay as patient prefer-ence to bariatric surgery.Khawali C, Ferraz MB, Zanella MT, Ferreira SR.Health Expectations. 2014;17(1):73-81.

Interacting inflammatory and growthfactor signals underlie the obesity-cancer link.Lashinger LM, Ford NA, Hursting SD. (Review).J Nutr. 2014;144(2):109-113.

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FROM THE ACADEMY

Laboratory testing for and diagnosis ofnutritional deficiences in pregnancybefore and after bariatric surgery.Gadgil MD, Chang HY, Richards TM et al.J Women’s Health. 2014;23(2):129-137.

No effect of caloric restriction on sali-vary cortisol levels in overweight menand women.Tam CS, Frost EA, Xie W, Rood J, Ravussin E,Redman LM, for the Pennington CALERIETeam. Metabolism. 2014;63(2):194-198.Abstract. Cyclic variation in salivarycortisol levels, a measure of hypothalamicpituitary adrenal activity, may be impor-tant in overweight individuals duringweight loss. This 24-week randomizedcontrolled CALERIE (ComprehensiveAssessment of Long-Term Effects ofReducing Intake of Energy) study in35 healthy overweight adults (meanbodymass index 27.8, 45%male, mean age38.1 years) measured salivary cortisollevels on the 4th inpatient day atbaseline and end of study to assess differ-ences across weight-loss groups (controlweight maintenance, 25% calorie restric-tion, 12.5% calorie restriction with 12.5%exercise calorie exertion). Samples werecollected at frequent intervals while par-ticipants consumed standardized mealsand supervised exercise, as indicated byrandomized treatment. Data wereanalyzed usingmixed model regression orpaired t-tests as appropriate. Resultsshowed highermeanmorning and diurnalcortisol saliva levels were strongly corre-lated at baseline to lower insulin sensi-tivity. This relationshipwas also correlatedto loss of visceral adipose tissue. Nochange was observed in the control group.A 10% change in body weight had littleoverall effect in total levels after mixedeffects analysis. Funding was provided bythe National Institutes of Health.

WELLNESS/PREVENTION

High dietary phosphorus intake isassociated with all-cause mortality:Results from NHANES III.Change AR, Lazo M, Appel LJ, Gutiérrez OM,Grams ME. Am J Clin Nutr. 2014;99(2):320-327.

Diet, cognition, and Alzheimer’s dis-ease: Food for thought.Otaegui-Arrazola A, Amiano P, Elbusto A,Urdaneta E, Martinez-Lage P. (Review).Eur JNutr. 2014;53(1):1-23.

May 2014 Volume 114 Number 5

WOMEN’S HEALTH

Intakes of anthocyanins and flavonesare associated with biomarkers of in-sulin resistance and inflammation inwomen.Jennings A, Welch AA, Spector T, Mac-gregor A, Cassidy A. J Nutr. 2014;144(2):202-208.

Weight and body compositionchanges during oral contraceptiveuse in obese and normal weightwomen.Mayeda ER, Torgal AH Westcoff CL. J Women’sHealth. 2014;23(1):38-43.

Apparent insufficiency of iodine sup-plementation in pregnancy.Pessah-Pollack R, Eschler DC, Pozhamy Z,Davies T. J Women’s Health. 2014;23(1):51-56.

SITES IN REVIEW

These web resources complement the orig-inal research article “Cruciferous Vegetable

Intake Is Inversely Correlated with CirculatingLevels of Proinflammatory Markers in Women”published in the May issue of the Journal(pp 700-708).

American Institute for CancerResearch: Broccoli & CruciferousVegetableshttp://www.aicr.org/foods-that-fight-cancer/broccoli-cruciferous.html

According to American Institute for Can-cer Research (AICR) estimates, ap-proximately one third of the annualcancer occurrences in the UnitedStates are preventable. Health-promotinglifestyle behaviors in the nutrition andphysical activity arenas play an integralrole in reducing cancer risk. The AICR’sBroccoli and Cruciferous Vegetableswebpage serves as a gateway to a varietyof resources highlighting the link be-tween cruciferous vegetable consumptionand cancer prevention.

JOURNAL OF THE ACAD

For ease of navigation, the webpage isorganized into six major sections: Intro-duction, Research, Tips, Recipes, Ask theExpert, and References, prominently dis-played via tabular graphic headings. TheIntroduction section features the origin ofthe cruciferous vegetable nomenclature aswell as nutrient and phytochemical profilesof select cruciferous vegetables. Definitionsfor highlighted phytochemicals are avail-able via balloon help.

The Research section summarizes andrates the existing evidence linking spe-cific food categories with reduced cancerrisk. Current areas of laboratory and hu-man research involving cruciferous vege-tables are presented. The Tips sectionprovides practical information regardingthe selection, storage, and preparation ofcruciferous vegetables. In the Recipessection, site users can browse a variety ofquick and easy cruciferous vegetable rec-ipes. Each recipe includes nutrient infor-mation per serving, and most includecolorful photos as well. The Ask theExpert section provides a forum for con-sumers to submit diet- and food-relatedcancer prevention questions. Responsesto previous frequently asked questionsare posted as well. A compilation ofpertinent research citations is provided inthe References section.

Oregon State University Linus PaulingInstitute Micronutrient InformationCenter: Cruciferous Vegetableshttp://lpi.oregonstate.edu/infocenter/foods/cruciferous/

The Cruciferous Vegetables webpage fromthe Oregon State University Linus PaulingMicronutrient Center offers extensive re-search findings on the topic of cruciferousvegetables and health. Commonly con-sumed cruciferous vegetables such as bokchoy, broccoli, Brussels sprouts, cauli-flower, and kale are identified along withtheir unique phytochemical properties.Research results for the role of cruciferousvegetables in disease prevention areorganized by disease state including can-cer overall as well as lung, colorectal,breast, and prostate cancer specifically.

Genetic variations and their potentialrole in modifying the effects of consumingcruciferous vegetables on cancer risk areaddressed. While specific intake recom-mendations for these vegetables haveyet to be established, potential minimumintakes are explored. In addition, specificvitamins, minerals, and phytochemicalsfound in cruciferous vegetables aredelineated.

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