matrix degradation of a small intestinal submucosa patch seeded with mitral valve interstitial cells...

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The Association for Academic Surgery and the Society of University Surgeons Are Proud to Present the Abstracts for the Sixth Annual Academic Surgical Congress Full text of all abstracts is available at www.academicsurgicalcongress.org February 1-3, 2011 Huntington Beach, California QUICKSHOT SESSION: TUESDAY, FEB 1, 2011 7:30 - 9:30 AM CARDIOTHORACIC 1: ADULT & CONGENITAL CARDIAC 1.1. Utilization of Permanent Epicardial Cardiac Pacing in Ultra-low Weight Premature Neonates with Congenital Heart Block. C. W. Shepard, B. A. Harvey, R. Bryant, J. D. St.Louis; University of Minnesota Amplatz Children’s Hospital, Minneapolis, MN 1.2. Impact Of An Intraoperative Improvement Initiative On Outcomes Following Pediatric Cardiac Surgery. P. Eghtesady, R. Pruett, T. Ashcraft, M. Miller, A. Gardner, A. Brar, P. Manning; Cincinnati Childrens Hospital Medical Center, Cincinnati, OH 1.3. Defining the Therapeutic Window for Pharmacologic Pre- and Post-Conditioning with the Gasotransmitter Hydro- gen Sulfide. M. A. Green, A. J. Reiffel, P. W. Henderson, D. D. Krijgh, N. Jimenez, J. A. Spector; Weill Cornell Medical College, Department of Plastic Surgery, New York, NY 1.4. Systemic Pretreatment With Dimethyloxalylglycine Increases Myocardial HIF-1a And VEGF Production And Improves Functional Recovery After Acute Ischemia/ Reperfusion. J. A. Poynter, 1 M. C. Manukyan, 1 Y. Wang, 1 B. D. Brewster, 1 D. R. Meldrum 1,2 ; 1 Dept. Of Surgery, Indiana University School of Medicine, Indianapolis, IN; 2 Cardiovascular Surgery, Methodist Hospital, Indianapolis, IN 1.5. Pretreatment With Intracoronary Mimosine Improves Post-ischemic Myocardial Functional Recovery. B. J. Crowe, 1 J. A. Poynter, 1 M. C. Manukyan, 1 Y. Wang, 1 B. D. Brewster, 1 C. H. Alvernaz, 1 A. C. Keck, 1 D. R. Meldrum 1,2 ; 1 Dept. Of Surgery, Indiana University School of Medicine, Indianapolis, IN; 2 Cardiovascular Surgery, Methodist Hospital, Indianapolis, IN 1.6. TGF-Alpha Does Not Protect Myocardium After Acute Ischemia/Reperfusion. A. C. Keck, 1 M. C. Manukyan, 1 J. A. Poynter, 1 Y. Wang, 1 B. D. Brewster, 1 D. R. Meldrum 1,2 ; 1 Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana; 2 Cardiovascular Surgery, Methodist Hospital, Indianapolis, Indiana 1.7. Interleukin-10 Protects The Ischemic Heart From Reper- fusion Injury. C. Alvernaz, 1 M. C. Manukyan, 1 J. A. Poynter, 1 Y. Wang, 1 B. D. Brewster, 1 B. R. Weil, 1 A. M. Abarbanell, 1 J. L. Herrmann, 1 B. J. Crowe, 1 A. C. Keck, 1 D. R. Meldrum 1,2 ; 1 Department of Surgery, Indiana School of Medicine, Indianapolis, Indiana; 2 Cardiovascular Surgery, Methodist Hospital, Indianapolis, Indiana 1.8. Mitral Valve Prolapse Gene Expression Profiling: A Microarray Study. D. G. Greenhouse, A. J. Murphy, G. Pintucci, P. Mignatti, A. C. Galloway, L. B. Balsam; New York University School of Medicine, New York, NY 1.9. Matrix Degradation of a Small Intestinal Submucosa Patch Seeded with Mitral Valve Interstitial Cells Facili- tates Tissue Remodeling: An In Vitro Study with a Novel Bioreactor. B. B. Scully, 1,2 K. N. Erskine, 2 C. Fan, 2 C. A. Durst, 2 M. Kwak, 2 J. Barzilla, 2 K. J. Grande-Allen, 2 D. L. S. Morales 1 ; 1 Baylor College of Medicine, Houston, TX; 2 Rice University, Houston, TX 1.10. What are the Impact of Cardiac Output and Left Ven- tricular Pressure on Coronary Flow and on Diastolic Coronary Perfusion? A Quantitative Coronary Flow Analysis Model for Cardiovascular Surgical Research. N. Tsirikos Karapanos, 1,2,3 D. Bramos, 2 A. Tsiftsi, 3 G. Saatsakis, 3 E. Skaltsiotis, 2,3 A. Kalantaridou, 2 D. Takos, 2 A. Tsaroucha, 3 E. Kairi, 3 G. Kottis, 3 S. Moulopoulos, 2 S. Toumanidis 2 ; 1 Mayo Clinic, Rochester, MN; 2 Department of Clinical Therapeutics, Alexandra Hospital, University of Athens, Athens, Athens; 3 2nd Surgical Department, Aretaieion Hospital, University of Athens, Athens, Athens 1.11. Cardiac Regeneration Following In Utero Fetal Sheep Myocardial Infarction Is Associated With Increased Cardiac Progenitor Cell Recruitment And Nkx2.5 Gene Expression Compared To Adult Infarcts. M. Allukian, 1 B. J. Herdrich, 1 D. M. Bermudez, 1 B. C. Chin, 1 L. Zhang, 2 X. Junwan, 2 W. Dorsett-Martin, 2 M. E. Mitchell, 2 J. H. Gorman, 1 R. C. Gorman, 1 K. W. Liechty 2 ; 1 Hospital of the University of Pennsylvania, Philadelphia, PA; 2 University of Mississippi Medical Center, Jackson, MS 0022-4804/$36.00 Ó 2011 Elsevier Inc. All rights reserved. 171 Journal of Surgical Research 165, 171–343 (2011)

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Page 1: Matrix Degradation of a Small Intestinal Submucosa Patch Seeded with Mitral Valve Interstitial Cells Facilitates Tissue Remodeling: An In Vitro Study with a Novel Bioreactor

Journal of Surgical Research 165, 171–343 (2011)

The Association for Academic Surgery and the Society of UniversitySurgeons Are Proud to Present the Abstracts for the Sixth Annual

Academic Surgical CongressFull text of all abstracts is available at www.academicsurgicalcongress.org

February 1-3, 2011Huntington Beach, California

QUICKSHOT SESSION: TUESDAY, FEB 1, 20117:30 - 9:30 AM

CARDIOTHORACIC 1: ADULT & CONGENITALCARDIAC

1.1. Utilization of Permanent Epicardial Cardiac Pacing inUltra-low Weight Premature Neonates with CongenitalHeart Block. C. W. Shepard, B. A. Harvey, R. Bryant, J. D.St.Louis; University of Minnesota Amplatz Children’s Hospital,Minneapolis, MN

1.2. Impact Of An Intraoperative Improvement InitiativeOn Outcomes Following Pediatric Cardiac Surgery.P. Eghtesady, R. Pruett, T. Ashcraft, M. Miller, A. Gardner,A. Brar, P. Manning; Cincinnati Childrens Hospital MedicalCenter, Cincinnati, OH

1.3. Defining theTherapeuticWindow forPharmacologicPre-and Post-Conditioning with the Gasotransmitter Hydro-gen Sulfide. M. A. Green, A. J. Reiffel, P. W. Henderson, D. D.Krijgh, N. Jimenez, J. A. Spector; Weill Cornell MedicalCollege, Department of Plastic Surgery, New York, NY

1.4. Systemic Pretreatment With DimethyloxalylglycineIncreases Myocardial HIF-1a And VEGF Production AndImproves Functional Recovery After Acute Ischemia/Reperfusion. J. A. Poynter,1 M. C. Manukyan,1 Y. Wang,1

B. D. Brewster,1 D. R. Meldrum1,2; 1Dept. Of Surgery,Indiana University School of Medicine, Indianapolis, IN;2Cardiovascular Surgery, Methodist Hospital, Indianapolis, IN

1.5. Pretreatment With Intracoronary Mimosine ImprovesPost-ischemic Myocardial Functional Recovery. B. J.Crowe,1 J. A. Poynter,1 M. C. Manukyan,1 Y. Wang,1 B. D.Brewster,1 C. H. Alvernaz,1 A. C. Keck,1 D. R. Meldrum1,2;1Dept. Of Surgery, Indiana University School of Medicine,Indianapolis, IN; 2Cardiovascular Surgery, Methodist Hospital,Indianapolis, IN

1.6. TGF-Alpha Does Not Protect Myocardium After AcuteIschemia/Reperfusion. A. C. Keck,1 M. C. Manukyan,1 J. A.Poynter,1 Y. Wang,1 B. D. Brewster,1 D. R. Meldrum1,2;1Department of Surgery, Indiana University School ofMedicine, Indianapolis, Indiana; 2Cardiovascular Surgery,Methodist Hospital, Indianapolis, Indiana

171

1.7. Interleukin-10 Protects The Ischemic Heart From Reper-fusion Injury. C. Alvernaz,1 M. C. Manukyan,1 J. A. Poynter,1

Y. Wang,1 B. D. Brewster,1 B. R. Weil,1 A. M. Abarbanell,1 J. L.Herrmann,1 B. J. Crowe,1 A. C. Keck,1 D. R. Meldrum1,2;1Department of Surgery, Indiana School of Medicine,Indianapolis, Indiana; 2Cardiovascular Surgery, MethodistHospital, Indianapolis, Indiana

1.8. Mitral Valve Prolapse Gene Expression Profiling: AMicroarray Study.D. G. Greenhouse, A. J. Murphy, G. Pintucci,P. Mignatti, A. C. Galloway, L. B. Balsam; New York UniversitySchool of Medicine, New York, NY

1.9. Matrix Degradation of a Small Intestinal SubmucosaPatch Seeded with Mitral Valve Interstitial Cells Facili-tates Tissue Remodeling: An In Vitro Study with a NovelBioreactor. B. B. Scully,1,2 K. N. Erskine,2 C. Fan,2 C. A.Durst,2 M. Kwak,2 J. Barzilla,2 K. J. Grande-Allen,2 D. L. S.Morales1; 1Baylor College of Medicine, Houston, TX; 2RiceUniversity, Houston, TX

1.10. What are the Impact of Cardiac Output and Left Ven-tricular Pressure on Coronary Flow and on DiastolicCoronary Perfusion? A Quantitative Coronary FlowAnalysis Model for Cardiovascular Surgical Research.N. Tsirikos Karapanos,1,2,3 D. Bramos,2 A. Tsiftsi,3

G. Saatsakis,3 E. Skaltsiotis,2,3 A. Kalantaridou,2 D. Takos,2

A. Tsaroucha,3 E. Kairi,3 G. Kottis,3 S. Moulopoulos,2 S.Toumanidis2; 1Mayo Clinic, Rochester, MN; 2Department ofClinical Therapeutics, Alexandra Hospital, University ofAthens, Athens, Athens; 32nd Surgical Department,Aretaieion Hospital, University of Athens, Athens, Athens

1.11. Cardiac Regeneration Following In Utero Fetal SheepMyocardial Infarction Is Associated With IncreasedCardiac Progenitor Cell Recruitment And Nkx2.5 GeneExpression Compared To Adult Infarcts. M. Allukian,1

B. J. Herdrich,1 D. M. Bermudez,1 B. C. Chin,1 L. Zhang,2

X. Junwan,2 W. Dorsett-Martin,2 M. E. Mitchell,2 J. H.Gorman,1 R. C. Gorman,1 K. W. Liechty2; 1Hospital of theUniversity of Pennsylvania, Philadelphia, PA; 2University ofMississippi Medical Center, Jackson, MS

0022-4804/$36.00� 2011 Elsevier Inc. All rights reserved.