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“MAP’s GROUP” Faculty of Pharmacy, SS Cyril & Methodius University SKOPJE, RM

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Page 1: “MAP’s GROUP” · professors) and 12 PhD students as ... SEE-ERA.NET Research Project: ... TRADITIONAL FOOD PRESERVATIVES AND SPICES

“MAP’s GROUP”

Faculty of Pharmacy,

SS Cyril & Methodius University

SKOPJE, RM

Page 2: “MAP’s GROUP” · professors) and 12 PhD students as ... SEE-ERA.NET Research Project: ... TRADITIONAL FOOD PRESERVATIVES AND SPICES

Institution The Faculty of Pharmacy is the most prominent high educational institution in the

field of pharmacy in the country, founded in 1977.

Undergraduate studies

Master in pharmacy (5 years)

Diploma in laboratory biomedicine (3 years)

Postgraduate studies

Master of sciences (M.Sci degree)

Doctor of philosophy (Ph.D. degree)

Specialization in 8 fields: Pharmaceutical technology

Toxicological chemistry

Medical biochemistry

Medicinal and aromatic plants (Pharmacognosy)

Sanitary chemistry

Examination and control of drug

Clinical pharmacy

Pharmaceutical informatics

One/Two years specialisation (Academic): • Phytotherapy • Cosmetology • Pharmacy legislation • Farmacoeconomy

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Infrastructure

It employs: 18 PhD holders (9 full professors, 4 associate and 4 assistant professors) and 12 PhD students as

permanent staff = 30.

http://www.ff.ukim.edu.mk.

Laboratories: 15

Amphitheaters: 1

Class-room: 3

All standard laboratory equipment

GC-FID-headspace (Clarus, Perkin Elmer)

GC-FID-MS, (Agilent Technologies)

Semipreparative HPLC –DAD

HPLC –DAD (4), (Waters, Agilent Technologies)

HPLC RR – DAD (1)

UV/VIS spektrofotometar, (Agilent Technologies)

Capillary Electrophoresis system,

IR spektrometar Perkin Elmer 1310,

ELISA reader,

PCR reader

Real Time PCR,,

….etc.

Page 4: “MAP’s GROUP” · professors) and 12 PhD students as ... SEE-ERA.NET Research Project: ... TRADITIONAL FOOD PRESERVATIVES AND SPICES

Infrastructure

Departments:

Institute of pharmaceutical chemistry

Institute of pharmacognosy Institute of pharmaceutical technology

Institute of applied chemistry and instrumental analysis

Institute of applied biochemistry

Centers:

7 different centers (drug quality control, pharmacoinformatics, natural products research, nanoscience technology in pharmacy, etc.).

Applied activity - (expertise, routine testing, expert reports, applicative projects, …etc.)

Research

Educations

• Educations • Research

Page 5: “MAP’s GROUP” · professors) and 12 PhD students as ... SEE-ERA.NET Research Project: ... TRADITIONAL FOOD PRESERVATIVES AND SPICES

MAP’s group Svetlana Kulevanova, Ph.D., Professor. [email protected]

Aneta Dimitrovska Ph.D., Professor. [email protected]

Tatjana Kadifkova Panovska, Ph.D., Assosiate Professor, [email protected]

Gjoshe Stefkov, Ph.D., Assistant Professor, [email protected]

Marija Karapandzova, Ph.D. student. [email protected]

Jelena Acevska Ph.D. student. [email protected]

Flora Sela Ph.D. student. [email protected]

Ivana Cvetkovic Ph.D. student. [email protected]

Institute of Pharmacognosy

Page 6: “MAP’s GROUP” · professors) and 12 PhD students as ... SEE-ERA.NET Research Project: ... TRADITIONAL FOOD PRESERVATIVES AND SPICES

Research interest

Exploring MAPs (domestic and regional).

Inventorisation of MAPs (mapping and resource assessment)

Conservation of MAPs (in situ and ex situ)

Chemical characterization of MAPs

Natural products chemistry

(essential oils and polyphenols in plants, fruits and food products)

Assessment of biological/pharmacological activity

Antioxidant activity (in vitro)

Antimicrobial activity (in vitro)

Antidiabetic activity (in vivo)

Antilipidemic activity (in vivo)

Antiinflamatory activity (in vivo)

Hepatoprotective activity (in vivo) Histomorfology of kidney and liver (in vivo)

Collaboration with other

members of the

University and

Institutions from the

region and Europe!

Page 7: “MAP’s GROUP” · professors) and 12 PhD students as ... SEE-ERA.NET Research Project: ... TRADITIONAL FOOD PRESERVATIVES AND SPICES

MAPs of interest - up to now

Teucrium polium Teucrium chamaedrys Teucrium montanum Centaurium erythrea Vaccinium myrthilus Vaccinium vitis-idaea Arctostaphylos uva-ursi Gentiana lutea L. Helichrysum plicatum DC

Lamiaceae Thymus sp. (18) Calamintha grandifolia (L.) Moench Calamintha nepeta (L.) Savi Clinopodium vulgare L. Acinos alpinus (L.) Moench Satureja montana L. Micromeria cristata (Hampe) Briseb.

Pinus peuce

Pinus nigra

Pinus silvestrys

Pinus mugo

Juniperus communis/Juniperus sp.

Sideritis scardica

Sideritis raeseri

Salvia off.

Origanum vulgare

Papaver somniferum

Craetegus sp.

Hypericum perforatum L.

….etc.

regional

level

national

level

antidiabetic

Page 8: “MAP’s GROUP” · professors) and 12 PhD students as ... SEE-ERA.NET Research Project: ... TRADITIONAL FOOD PRESERVATIVES AND SPICES

Completed and ongoing projects:

Pharmacognosy and Taxonomy of the species of Lamiaceae in the flora of Rebublic of Macedonia, (1994 – 1996), Institute of Pharmacognosy, Faculty of Pharmacy, Skopje, Ministry of Science, R. of Macedonia.

Chemotaxonomy, phytochemistry and pharmacognosy of the species: Teucrium, Calamintha, Acinos, Satureja, Clinopodium and Micromeria in the flora of Republic of Macedonia, Ministry of Science, R. of Macedonia, 1999-2001.

Antioxidant activity of the plant species from Macedonian flora and their possible use as hepatoprotective agents, Ministry of Science, R. of Macedonia, 2003-2006. COST action 926: EU Commission, Brussels, 2005-2008. Impact of new technologies on the health benefits and safety of bioactive plant compounds,

SEE-ERA.NET Research Project: Exploring the molecular biodiversity of

medicinal and aromatic plants; 2007-2008;

Characterization of chemical composition and biological activity of

Pinus (Pinaceae) and Juniperus (Cupresaceae) species from

Macedonian flora and evaluation of possibilities for their medicinal

and/or commercial use (national level)

Page 9: “MAP’s GROUP” · professors) and 12 PhD students as ... SEE-ERA.NET Research Project: ... TRADITIONAL FOOD PRESERVATIVES AND SPICES

Projects

4 SEE-ERA.NET Plus aplications:

AROMATIC AND MEDICINAL PLANTS - MARKET-ORIENTED ON-FARM DEVELOPMENT OF MORE SUSTAINABLE CULTIVATION TECHNIQUES FOR AROMATIC AND MEDICINAL PLANTS TO BE GROWN IN ALBANIA AND MACEDONIA.

SEE-ERA.NET PLUS JOINT CALL - SEEERAPLUS (2010)

ASSESSMENT AND COMPARISON OF THE BIOLOGICAL ACTIVITIES OF NATURAL TRADITIONAL FOOD PRODUCTS FROM DIFFERENT WESTERN BALKAN REGIONS.

SEE-ERA.NET PLUS JOINT CALL – SEEERAPLUS (2010)

A MODEL APPROACH FOR THE CONSERVATION AND THE SUSTAINABLE EXPLOITATION OF THE INDIGENOUS SIDERITIS SPP. (MOUNTAIN TEA) TRADITIONALLY USED IN THE SEE, WB COUNTRIES.

SEE-ERA.NET PLUS JOINT CALL - SEEERAPLUS (2011-12)

CONSERVATION AND UTILIZATION OF THE DIVERSITY OF SAGE SPECIES (SALVIA SPP.) – TRADITIONAL FOOD PRESERVATIVES AND SPICES.

SEE-ERA.NET PLUS JOINT CALL – SEEERAPLUS (2011-12)

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RESOUCE ASSESMENT OF

BLUBERRIES ON OSOGOVO MTN

FUTURE PERSPECITVES OF

POPPY IN R. MACEDONIA

Page 11: “MAP’s GROUP” · professors) and 12 PhD students as ... SEE-ERA.NET Research Project: ... TRADITIONAL FOOD PRESERVATIVES AND SPICES

Thank you for your

attention !