Lupus Nephritis

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Post on 07-May-2015

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<ul><li>1.Lupus Nephritis</li></ul> <p>2. 3. RBC Casts 4. WHO Class I Lupus Nephritis Minimal Mesangial Immunoperoxidase staining shows C1q 5. WHO Class II Immunoperoxidase stain: Mesangial IgG deposits 6. WHO Class II Lupus Nephritis Mesangial Proliferative 7. WHO Class III Lupus Nephritis (Focal Proliferative) Hematoxylin/Lissamine Green Stain: 50% of the glomerular tuft involvement With areas of focal necrosis 8. WHO Class III Lupus Nephritis 9. WHO Class III Lupus Nephritis 10. WHO Class IV Lupus Nephritis Diffuse Proliferative Immunoperoxidase Stain: 50% of the Glomerular Tuft involved 11. WHO Class IV Lupus Nephritis H &amp; E Stain: Diffuse increase in matrix and hypercellularity 12. WHO Class VMembranous EM: Electron-dense immune deposits on the outer surface of BM, separated by spikes of exuberant BM-like material (mainly laminin) 13. WHO Class V Lupus Nephritis Silver Methenamine Stain: Silver positive spikes along the peripheral capillary wall 14. WHO Class V Lupus Nephritis 15. WHO Class VI Lupus Nephritis Advanced Sclerosis Hematoxylin/Lissamine Green Stain: Sclerosis of 90% of the glomerulus 16. WHO Class VI Lupus Nephritis </p>