low dose nifedipine controls hypertension
TRANSCRIPT
Low dose nifedipine controls hypertension
Few studies have assessed the effects of low doses of nifedipine. In an open study, a significant reduction in BP was observed in 47/52 patients with essential hypertension within 5 min of administration of oral nifedipine 5mg. Five patients failed to respond despite a repeat nifedipine dose. Transient headache and mild headache were reported in 3 patients each.
lerjes-Sanchez, et al. ' ... believe that the use of the Smg dose of oral nifedipine, alone or in conjunction with other drugs, could be extended to other hypertensive syndromes . .. ' Jerjes-Sanchez C, Ibarra-Perez C. Velazquez-Rodriguez E, De los RiosIbarra MO, Rosado-Buzzo A. et al. Short-term efficacy and safety of a single five-milligram dose of oral nifedipine in uncontrolled essential systemic hypertension. American Journal of Cardiology 68: 123-125. 1 Jul 1991 7001
ISSN 0156-2703/91/07/3·0007/0$01.00/0 e Adis I11tmllltio1llll Ltd 7
INPHARMA®/3 Jul 1991