lltech brain imaging july 2012
TRANSCRIPT
1 © LLTECH 2011 Copyright LLTech 2012 – www.lltech.fr
LLTECH Brain images
2 © LLTECH 2011 Copyright LLTech 2012 – www.lltech.fr
Rat brain
Architectural and cellular informa;on seen at various scales
Myelinated fibers visible
1 mm
500 µm
100 µm
3 © LLTECH 2011 Copyright LLTech 2012 – www.lltech.fr
Neurons cell bodies (dark dots)
Axons/myelin fibers
Capillary
50µm
50µm
50µm 500µm
Human epilep;c parenchyma
Cortex
White maHer
Axons bundles
4 © LLTECH 2011 Copyright LLTech 2012 – www.lltech.fr
Stratum granulosum of the gyrus dentatus
Hippocampus : Coronal sec;on (leK side)
100µm
500µm
CA4 Field
CA1 field of the cornus ammonis
Hippocampal sulcus
Stratum radiatus of the CA1 field
Pyramidal neurons of the
CA4 field 50µm
5 © LLTECH 2011 Copyright LLTech 2012 – www.lltech.fr © LLTECH 2011
Collagen-‐rich matrix Wide fascicles of tumour cells
Large capillary
Fibroblas;c meningioma grade I
500µm
100µm 200µm 200µm
6 © LLTECH 2011 Copyright LLTech 2012 – www.lltech.fr
Transi;onal meningioma grade I
Psammoma surrounding a calcifica;on
Whorls forma;on
Collagen-‐rich matrix
500µm
100µm
50µm
50µm
71679
7 © LLTECH 2011 Copyright LLTech 2012 – www.lltech.fr
Choroid Plexus Papilloma : Xanthomatous changes
Characteris;c cauliflower-‐like masses
Papilla filled with blood
Empty papilla
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Arrows: Fibers transverse cut
Spinal cord : normal ;ssue
500 µm
100 µm
100 µm
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Spinal cord with Iysolecithin-‐induced injury
Lesion
500 µm
10 © LLTECH 2011 Copyright LLTech 2012 – www.lltech.fr
Healthy area: -‐ regular architecture -‐ longitudinally packed fibers
Injured spinal cord – longitudinal cut
Injured area: -‐ disorganized architecture -‐ no visible regular fiber arrangement
-‐ modified contrast 100 µm
100 µm